Rousettus aegyptiacus (Egyptian rousette): 107503061 Help Entry 107503061         CDS       T06036                                  Gene name PRKCG Definition (RefSeq) protein kinase C gamma type isoform X1   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray01521   EGFR tyrosine kinase inhibitor resistance ray04010   MAPK signaling pathway ray04012   ErbB signaling pathway ray04014   Ras signaling pathway ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04066   HIF-1 signaling pathway ray04070   Phosphatidylinositol signaling system ray04071   Sphingolipid signaling pathway ray04150   mTOR signaling pathway ray04270   Vascular smooth muscle contraction ray04310   Wnt signaling pathway ray04370   VEGF signaling pathway ray04510   Focal adhesion ray04540   Gap junction ray04613   Neutrophil extracellular trap formation ray04650   Natural killer cell mediated cytotoxicity ray04666   Fc gamma R-mediated phagocytosis ray04670   Leukocyte transendothelial migration ray04713   Circadian entrainment ray04720   Long-term potentiation ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04726   Serotonergic synapse ray04727   GABAergic synapse ray04728   Dopaminergic synapse ray04730   Long-term depression ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04919   Thyroid hormone signaling pathway ray04921   Oxytocin signaling pathway ray04925   Aldosterone synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04929   GnRH secretion ray04935   Growth hormone synthesis, secretion and action ray04960   Aldosterone-regulated sodium reabsorption ray04961   Endocrine and other factor-regulated calcium reabsorption ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray05017   Spinocerebellar ataxia ray05022   Pathways of neurodegeneration - multiple diseases ray05031   Amphetamine addiction ray05032   Morphine addiction ray05143   African trypanosomiasis ray05146   Amoebiasis ray05161   Hepatitis B ray05163   Human cytomegalovirus infection ray05170   Human immunodeficiency virus 1 infection ray05171   Coronavirus disease - COVID-19 ray05200   Pathways in cancer ray05205   Proteoglycans in cancer ray05206   MicroRNAs in cancer ray05214   Glioma ray05223   Non-small cell lung cancer ray05225   Hepatocellular carcinoma ray05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ray00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     107503061 (PRKCG)    04012 ErbB signaling pathway     107503061 (PRKCG)    04014 Ras signaling pathway     107503061 (PRKCG)    04015 Rap1 signaling pathway     107503061 (PRKCG)    04310 Wnt signaling pathway     107503061 (PRKCG)    04370 VEGF signaling pathway     107503061 (PRKCG)    04066 HIF-1 signaling pathway     107503061 (PRKCG)    04020 Calcium signaling pathway     107503061 (PRKCG)    04070 Phosphatidylinositol signaling system     107503061 (PRKCG)    04071 Sphingolipid signaling pathway     107503061 (PRKCG)    04150 mTOR signaling pathway     107503061 (PRKCG)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     107503061 (PRKCG)    04540 Gap junction     107503061 (PRKCG)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     107503061 (PRKCG)    04650 Natural killer cell mediated cytotoxicity     107503061 (PRKCG)    04666 Fc gamma R-mediated phagocytosis     107503061 (PRKCG)    04670 Leukocyte transendothelial migration     107503061 (PRKCG)   09152 Endocrine system    04911 Insulin secretion     107503061 (PRKCG)    04929 GnRH secretion     107503061 (PRKCG)    04921 Oxytocin signaling pathway     107503061 (PRKCG)    04935 Growth hormone synthesis, secretion and action     107503061 (PRKCG)    04918 Thyroid hormone synthesis     107503061 (PRKCG)    04919 Thyroid hormone signaling pathway     107503061 (PRKCG)    04928 Parathyroid hormone synthesis, secretion and action     107503061 (PRKCG)    04916 Melanogenesis     107503061 (PRKCG)    04925 Aldosterone synthesis and secretion     107503061 (PRKCG)   09153 Circulatory system    04270 Vascular smooth muscle contraction     107503061 (PRKCG)   09154 Digestive system    04970 Salivary secretion     107503061 (PRKCG)    04971 Gastric acid secretion     107503061 (PRKCG)    04972 Pancreatic secretion     107503061 (PRKCG)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     107503061 (PRKCG)    04961 Endocrine and other factor-regulated calcium reabsorption     107503061 (PRKCG)   09156 Nervous system    04724 Glutamatergic synapse     107503061 (PRKCG)    04727 GABAergic synapse     107503061 (PRKCG)    04725 Cholinergic synapse     107503061 (PRKCG)    04728 Dopaminergic synapse     107503061 (PRKCG)    04726 Serotonergic synapse     107503061 (PRKCG)    04720 Long-term potentiation     107503061 (PRKCG)    04730 Long-term depression     107503061 (PRKCG)    04723 Retrograde endocannabinoid signaling     107503061 (PRKCG)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107503061 (PRKCG)   09159 Environmental adaptation    04713 Circadian entrainment     107503061 (PRKCG)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107503061 (PRKCG)    05206 MicroRNAs in cancer     107503061 (PRKCG)    05205 Proteoglycans in cancer     107503061 (PRKCG)    05231 Choline metabolism in cancer     107503061 (PRKCG)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     107503061 (PRKCG)    05214 Glioma     107503061 (PRKCG)    05223 Non-small cell lung cancer     107503061 (PRKCG)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     107503061 (PRKCG)    05022 Pathways of neurodegeneration - multiple diseases     107503061 (PRKCG)   09165 Substance dependence    05031 Amphetamine addiction     107503061 (PRKCG)    05032 Morphine addiction     107503061 (PRKCG)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     107503061 (PRKCG)    05161 Hepatitis B     107503061 (PRKCG)    05171 Coronavirus disease - COVID-19     107503061 (PRKCG)    05163 Human cytomegalovirus infection     107503061 (PRKCG)   09174 Infectious disease: parasitic    05146 Amoebiasis     107503061 (PRKCG)    05143 African trypanosomiasis     107503061 (PRKCG)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     107503061 (PRKCG)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ray01001]     107503061 (PRKCG) Enzymes [BR:ray01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      107503061 (PRKCG) Protein kinases [BR:ray01001]  Serine/threonine kinases: AGC group   PKC family [OT]    107503061 (PRKCG) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C Kinase-like APH Motif Other DBs NCBI-GeneID:  107503061 NCBI-ProteinID:  XP_015986402 LinkDB All DBs Position Unknown AA seq 697 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTADEIHITVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKENVFPGTTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPAKRLGS GLDGEPTIRAHGFFRWIDWDRLERLEIPPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPISPTPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atggcaggcctgggccccggcggcggcgattcagagggggggccccggcccctattttgt agaaagggggctctgaggcagaaggtggtccacgaagtcaagagccacaagttcaccgct cgcttcttcaagcagccaaccttctgcagccactgcaccgacttcatctgggggattgga aaacagggcctgcaatgtcaagtctgcagttttgtggttcatcggcgatgccacgaattt gtgaccttcgagtgtccaggcgcggggaagggcccccagacggacgatccccggaacaag cacaagttccgcctgcacagctacagtagccccaccttctgcgaccactgcggctccctc ctttacgggctggtacatcagggcatgaaatgctcctgctgcgagatgaacgtgcatcgg cgctgcgtgcgcagcgtgccctctctgtgcggcgtggaccacacagagcgtcgcgggcgc ctgcagttggaaatccgggctccgaccgcagatgagatccacatcacggttggtgaggcc cggaatctcatcccaatggaccccaatggtctgtctgacccttatgtgaaactgaagctc attccagaccctcggaacttgacaaaacagaagacccggaccgtgaaagccactctgaac cctgtgtggaacgagacctttgtgttcaacctgaagcctggggatgtggaacgccggctc agtgtggaggtgtgggactgggaccggacctcccgcaatgacttcatgggtgccatgtct tttggggtctcagagctgctcaaggcaccagtggatggatggtacaagttactgaaccag gaggagggcgaatattacaatgtgccggtggctgatgctgacaactgcagcctcctccag aagtttgaggcctgtaactaccccctggaactatatgagcgagtgcggatgggtccttcc tcctctcccatcccctccccatcccctagtcccaccgactccaagcgctgtttctttggg gcaagtcctggacgtctgcacatctctgacttcagcttcctcatggttctggggaaaggc agctttgggaaggtgatgctggccgagcgtaggggctccgatgagctctacgccatcaag atcctgaagaaagacgtgatcgtacaggatgatgatgtggactgcaccctggtggagaaa cgcgtgctggccctgggaggcagaggccccggaggccggccccactttctcacccagctc cactccaccttccagaccccggatcgcttgtattttgtgatggaatatgtcaccgggggc gacttgatgtaccacattcagcagctgggcaaatttaaggagccccatgcagcgttctat gcagcggaaatcgccatcggcctcttcttccttcacaatcagggcatcatctaccgggac ctgaaattggacaatgtgatgctcgacgcggaaggacacatcaaaatcactgacttcggc atgtgtaaagaaaacgttttccccgggaccacaacccgcactttctgcgggaccccagac tacatagccccggagattattgcctaccagccctatgggaaatctgttgactggtggtcc tttggggtgctgctgtatgaaatgttggcaggacagcccccctttgatggggaggatgaa gaggagctgtttcaggctatcatggaacaaaccgtcacctaccccaagtctctctccagg gaagccgtggccatctgcaaggggtttctaaccaaacaccctgcaaagcgcctgggttca gggcttgacggggagcccaccatccgtgcccatggctttttccgctggatcgactgggac cggctggaacggttggagatcccacctccgtttagaccccgcccgtgtggccgcagcggc gagaacttcgacaagttcttcacgcgggcggcgccagcgctgacgcccccggaccgccta gttctggccagcatcgaccaggcagatttccaaggcttcacctacgtaaacccggatttc gtgcacccggatgcccgcagccccatcagcccaacgcctgtgccagtcatgtaa

Rousettus aegyptiacus (Egyptian rousette): 107510307 Help Entry 107510307         CDS       T06036                                  Gene name PRKCA Definition (RefSeq) protein kinase C alpha type isoform X1   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray01521   EGFR tyrosine kinase inhibitor resistance ray04010   MAPK signaling pathway ray04012   ErbB signaling pathway ray04014   Ras signaling pathway ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04066   HIF-1 signaling pathway ray04070   Phosphatidylinositol signaling system ray04071   Sphingolipid signaling pathway ray04072   Phospholipase D signaling pathway ray04150   mTOR signaling pathway ray04151   PI3K-Akt signaling pathway ray04261   Adrenergic signaling in cardiomyocytes ray04270   Vascular smooth muscle contraction ray04310   Wnt signaling pathway ray04360   Axon guidance ray04370   VEGF signaling pathway ray04510   Focal adhesion ray04540   Gap junction ray04613   Neutrophil extracellular trap formation ray04650   Natural killer cell mediated cytotoxicity ray04664   Fc epsilon RI signaling pathway ray04666   Fc gamma R-mediated phagocytosis ray04670   Leukocyte transendothelial migration ray04713   Circadian entrainment ray04720   Long-term potentiation ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04726   Serotonergic synapse ray04727   GABAergic synapse ray04728   Dopaminergic synapse ray04730   Long-term depression ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04919   Thyroid hormone signaling pathway ray04921   Oxytocin signaling pathway ray04925   Aldosterone synthesis and secretion ray04926   Relaxin signaling pathway ray04928   Parathyroid hormone synthesis, secretion and action ray04929   GnRH secretion ray04933   AGE-RAGE signaling pathway in diabetic complications ray04935   Growth hormone synthesis, secretion and action ray04960   Aldosterone-regulated sodium reabsorption ray04961   Endocrine and other factor-regulated calcium reabsorption ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray05017   Spinocerebellar ataxia ray05022   Pathways of neurodegeneration - multiple diseases ray05031   Amphetamine addiction ray05032   Morphine addiction ray05143   African trypanosomiasis ray05146   Amoebiasis ray05161   Hepatitis B ray05163   Human cytomegalovirus infection ray05164   Influenza A ray05170   Human immunodeficiency virus 1 infection ray05171   Coronavirus disease - COVID-19 ray05200   Pathways in cancer ray05205   Proteoglycans in cancer ray05206   MicroRNAs in cancer ray05214   Glioma ray05223   Non-small cell lung cancer ray05225   Hepatocellular carcinoma ray05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ray00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     107510307 (PRKCA)    04012 ErbB signaling pathway     107510307 (PRKCA)    04014 Ras signaling pathway     107510307 (PRKCA)    04015 Rap1 signaling pathway     107510307 (PRKCA)    04310 Wnt signaling pathway     107510307 (PRKCA)    04370 VEGF signaling pathway     107510307 (PRKCA)    04066 HIF-1 signaling pathway     107510307 (PRKCA)    04020 Calcium signaling pathway     107510307 (PRKCA)    04070 Phosphatidylinositol signaling system     107510307 (PRKCA)    04072 Phospholipase D signaling pathway     107510307 (PRKCA)    04071 Sphingolipid signaling pathway     107510307 (PRKCA)    04151 PI3K-Akt signaling pathway     107510307 (PRKCA)    04150 mTOR signaling pathway     107510307 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     107510307 (PRKCA)    04540 Gap junction     107510307 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     107510307 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     107510307 (PRKCA)    04664 Fc epsilon RI signaling pathway     107510307 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     107510307 (PRKCA)    04670 Leukocyte transendothelial migration     107510307 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     107510307 (PRKCA)    04929 GnRH secretion     107510307 (PRKCA)    04912 GnRH signaling pathway     107510307 (PRKCA)    04921 Oxytocin signaling pathway     107510307 (PRKCA)    04926 Relaxin signaling pathway     107510307 (PRKCA)    04935 Growth hormone synthesis, secretion and action     107510307 (PRKCA)    04918 Thyroid hormone synthesis     107510307 (PRKCA)    04919 Thyroid hormone signaling pathway     107510307 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     107510307 (PRKCA)    04916 Melanogenesis     107510307 (PRKCA)    04925 Aldosterone synthesis and secretion     107510307 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     107510307 (PRKCA)    04270 Vascular smooth muscle contraction     107510307 (PRKCA)   09154 Digestive system    04970 Salivary secretion     107510307 (PRKCA)    04971 Gastric acid secretion     107510307 (PRKCA)    04972 Pancreatic secretion     107510307 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     107510307 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     107510307 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     107510307 (PRKCA)    04727 GABAergic synapse     107510307 (PRKCA)    04725 Cholinergic synapse     107510307 (PRKCA)    04728 Dopaminergic synapse     107510307 (PRKCA)    04726 Serotonergic synapse     107510307 (PRKCA)    04720 Long-term potentiation     107510307 (PRKCA)    04730 Long-term depression     107510307 (PRKCA)    04723 Retrograde endocannabinoid signaling     107510307 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107510307 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     107510307 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     107510307 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107510307 (PRKCA)    05206 MicroRNAs in cancer     107510307 (PRKCA)    05205 Proteoglycans in cancer     107510307 (PRKCA)    05231 Choline metabolism in cancer     107510307 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     107510307 (PRKCA)    05214 Glioma     107510307 (PRKCA)    05223 Non-small cell lung cancer     107510307 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     107510307 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     107510307 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     107510307 (PRKCA)    05032 Morphine addiction     107510307 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     107510307 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     107510307 (PRKCA)    05161 Hepatitis B     107510307 (PRKCA)    05171 Coronavirus disease - COVID-19     107510307 (PRKCA)    05164 Influenza A     107510307 (PRKCA)    05163 Human cytomegalovirus infection     107510307 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     107510307 (PRKCA)    05143 African trypanosomiasis     107510307 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     107510307 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ray01001]     107510307 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ray04131]     107510307 (PRKCA) Enzymes [BR:ray01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      107510307 (PRKCA) Protein kinases [BR:ray01001]  Serine/threonine kinases: AGC group   PKC family [OT]    107510307 (PRKCA) Membrane trafficking [BR:ray04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     107510307 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 C1_2 Kinase-like Motif Other DBs NCBI-GeneID:  107510307 NCBI-ProteinID:  XP_015999180 LinkDB All DBs Position Unknown AA seq 719 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMEGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVVSQGRSPFPEPQSPQSWRCPTHPPSWREEASDPRPPQGKRLP LPSVLWSEQGQTRPRGGCGSSVLTELSNSVAAESPPPARLNSKGGLLGVWILWTRNSWL NT seq 2160 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgattccacggcgtctcaggacgtggccaaccgcttc gcgcgcaaaggggcgctgagacagaagaacgtgcatgaggtgaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgtcactttttcctgtccgggtgcggataagggacccgacactgatgaccccaggagc aagcacaagtttaaaatccacacttacggaagccccaccttctgcgatcactgtgggtca ctgctgtacggacttatccaccaagggatgaaatgcgacacctgcgacatgaacgtgcac aagcagtgcgtaataaacgtccccagcctctgcgggatggaccacacagagaagcggggg cggatctacctgaaggccgaggtcaccgacgaaaagctccacgtcacagtacgagatgca aagaatctcatccctatggatccaaatggactctcagacccttacgtgaagctgaaactt attcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactgaac ccccagtggaatgagtcgttcaccttcaaattaaaaccttcggataaagaccgacgactg tccgtggaaatctgggattgggatcgcacaacaaggaacgacttcatgggctccctttcc ttcggcgtttcggagctgatgaagatgccggccagtggatggtacaagctgcttaaccaa gaagaaggtgagtactacaacgtgcccattccagaaggagacgaagaagggaacgcggag ctccggcagaaattcgagaaagccaagcttggccccgctggtaacaaagtaatcagtcct tcagaagacaggagacaaccttccaacaaccttgacagggtgaagctcacggacttcaat ttcctcatggtcctggggaaggggagttttggaaaggtgatgctggccgacaggaaggga acagaagaactgtacgctatcaagatcctgaagaaggacgtggtgatccaggacgatgac gtggaatgcaccatggtagagaagcgagtgctggctttgctcgacaagccgccgttcctg acacagctgcactcctgcttccagacggtggatcggctctacttcgtcatggaatacgtc aacggcggggacctcatgtaccacatccagcaagtaggaaaatttaaggaaccccaagca gtattctatgcagcagagatttccattggattgttctttcttcataaacgaggaatcatt tatagggacctgaagttagataacgtcatgctggattcggaagggcacatcaagatcgcc gacttcgggatgtgcaaggagcacatgatggagggagtcacaaccaggaccttctgcggg accccagactacatcgccccggagataatcgcttatcagccgtacgggaaatctgtggac tggtgggcctacggcgtcctgttatatgaaatgctggctgggcagcccccattcgatggt gaagatgaagacgagctgtttcagtctataatggagcacaacgtttcttatccgaaatct ttatccaaggaggccgtttccatctgcaaaggactgatgaccaaacatcccggcaagcgt ctgggctgcgggcccgagggggaacgggacgtgcgagaacacgccttcttccggaggatc gactgggagaaactggagaacagggagatccagccgccgttcaagcccaaagtggtgagc caagggcgcagcccgtttcctgagccccagtccccccaatcctggaggtgtcccacccac cctccttcttggagagaggaggccagtgacccccggcctccacagggcaagcgcctgccc ttgccgtcggttctgtggtccgagcaagggcagaccaggccgcgaggcgggtgcgggtct tctgtcctcacagagctgtccaatagcgtggctgcagagagccccccaccagcccgatta aacagcaagggaggtctgcttggggtttggattttgtggactcggaattcctggctctga

Rousettus aegyptiacus (Egyptian rousette): 107516091 Help Entry 107516091         CDS       T06036                                  Gene name PRKCB Definition (RefSeq) protein kinase C beta type isoform X1   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism ray  Rousettus aegyptiacus (Egyptian rousette) Pathway ray01521   EGFR tyrosine kinase inhibitor resistance ray04010   MAPK signaling pathway ray04012   ErbB signaling pathway ray04014   Ras signaling pathway ray04015   Rap1 signaling pathway ray04020   Calcium signaling pathway ray04062   Chemokine signaling pathway ray04064   NF-kappa B signaling pathway ray04066   HIF-1 signaling pathway ray04070   Phosphatidylinositol signaling system ray04071   Sphingolipid signaling pathway ray04150   mTOR signaling pathway ray04270   Vascular smooth muscle contraction ray04310   Wnt signaling pathway ray04370   VEGF signaling pathway ray04510   Focal adhesion ray04540   Gap junction ray04613   Neutrophil extracellular trap formation ray04650   Natural killer cell mediated cytotoxicity ray04662   B cell receptor signaling pathway ray04666   Fc gamma R-mediated phagocytosis ray04670   Leukocyte transendothelial migration ray04713   Circadian entrainment ray04720   Long-term potentiation ray04723   Retrograde endocannabinoid signaling ray04724   Glutamatergic synapse ray04725   Cholinergic synapse ray04726   Serotonergic synapse ray04727   GABAergic synapse ray04728   Dopaminergic synapse ray04730   Long-term depression ray04750   Inflammatory mediator regulation of TRP channels ray04911   Insulin secretion ray04912   GnRH signaling pathway ray04916   Melanogenesis ray04918   Thyroid hormone synthesis ray04919   Thyroid hormone signaling pathway ray04921   Oxytocin signaling pathway ray04925   Aldosterone synthesis and secretion ray04928   Parathyroid hormone synthesis, secretion and action ray04929   GnRH secretion ray04931   Insulin resistance ray04933   AGE-RAGE signaling pathway in diabetic complications ray04935   Growth hormone synthesis, secretion and action ray04960   Aldosterone-regulated sodium reabsorption ray04961   Endocrine and other factor-regulated calcium reabsorption ray04970   Salivary secretion ray04971   Gastric acid secretion ray04972   Pancreatic secretion ray04973   Carbohydrate digestion and absorption ray05017   Spinocerebellar ataxia ray05022   Pathways of neurodegeneration - multiple diseases ray05031   Amphetamine addiction ray05032   Morphine addiction ray05140   Leishmaniasis ray05143   African trypanosomiasis ray05146   Amoebiasis ray05161   Hepatitis B ray05163   Human cytomegalovirus infection ray05164   Influenza A ray05170   Human immunodeficiency virus 1 infection ray05171   Coronavirus disease - COVID-19 ray05200   Pathways in cancer ray05205   Proteoglycans in cancer ray05206   MicroRNAs in cancer ray05214   Glioma ray05223   Non-small cell lung cancer ray05225   Hepatocellular carcinoma ray05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:ray00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     107516091 (PRKCB)    04012 ErbB signaling pathway     107516091 (PRKCB)    04014 Ras signaling pathway     107516091 (PRKCB)    04015 Rap1 signaling pathway     107516091 (PRKCB)    04310 Wnt signaling pathway     107516091 (PRKCB)    04370 VEGF signaling pathway     107516091 (PRKCB)    04064 NF-kappa B signaling pathway     107516091 (PRKCB)    04066 HIF-1 signaling pathway     107516091 (PRKCB)    04020 Calcium signaling pathway     107516091 (PRKCB)    04070 Phosphatidylinositol signaling system     107516091 (PRKCB)    04071 Sphingolipid signaling pathway     107516091 (PRKCB)    04150 mTOR signaling pathway     107516091 (PRKCB)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     107516091 (PRKCB)    04540 Gap junction     107516091 (PRKCB)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     107516091 (PRKCB)    04650 Natural killer cell mediated cytotoxicity     107516091 (PRKCB)    04662 B cell receptor signaling pathway     107516091 (PRKCB)    04666 Fc gamma R-mediated phagocytosis     107516091 (PRKCB)    04670 Leukocyte transendothelial migration     107516091 (PRKCB)    04062 Chemokine signaling pathway     107516091 (PRKCB)   09152 Endocrine system    04911 Insulin secretion     107516091 (PRKCB)    04929 GnRH secretion     107516091 (PRKCB)    04912 GnRH signaling pathway     107516091 (PRKCB)    04921 Oxytocin signaling pathway     107516091 (PRKCB)    04935 Growth hormone synthesis, secretion and action     107516091 (PRKCB)    04918 Thyroid hormone synthesis     107516091 (PRKCB)    04919 Thyroid hormone signaling pathway     107516091 (PRKCB)    04928 Parathyroid hormone synthesis, secretion and action     107516091 (PRKCB)    04916 Melanogenesis     107516091 (PRKCB)    04925 Aldosterone synthesis and secretion     107516091 (PRKCB)   09153 Circulatory system    04270 Vascular smooth muscle contraction     107516091 (PRKCB)   09154 Digestive system    04970 Salivary secretion     107516091 (PRKCB)    04971 Gastric acid secretion     107516091 (PRKCB)    04972 Pancreatic secretion     107516091 (PRKCB)    04973 Carbohydrate digestion and absorption     107516091 (PRKCB)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     107516091 (PRKCB)    04961 Endocrine and other factor-regulated calcium reabsorption     107516091 (PRKCB)   09156 Nervous system    04724 Glutamatergic synapse     107516091 (PRKCB)    04727 GABAergic synapse     107516091 (PRKCB)    04725 Cholinergic synapse     107516091 (PRKCB)    04728 Dopaminergic synapse     107516091 (PRKCB)    04726 Serotonergic synapse     107516091 (PRKCB)    04720 Long-term potentiation     107516091 (PRKCB)    04730 Long-term depression     107516091 (PRKCB)    04723 Retrograde endocannabinoid signaling     107516091 (PRKCB)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     107516091 (PRKCB)   09159 Environmental adaptation    04713 Circadian entrainment     107516091 (PRKCB)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     107516091 (PRKCB)    05206 MicroRNAs in cancer     107516091 (PRKCB)    05205 Proteoglycans in cancer     107516091 (PRKCB)    05231 Choline metabolism in cancer     107516091 (PRKCB)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     107516091 (PRKCB)    05214 Glioma     107516091 (PRKCB)    05223 Non-small cell lung cancer     107516091 (PRKCB)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     107516091 (PRKCB)    05022 Pathways of neurodegeneration - multiple diseases     107516091 (PRKCB)   09165 Substance dependence    05031 Amphetamine addiction     107516091 (PRKCB)    05032 Morphine addiction     107516091 (PRKCB)   09167 Endocrine and metabolic disease    04931 Insulin resistance     107516091 (PRKCB)    04933 AGE-RAGE signaling pathway in diabetic complications     107516091 (PRKCB)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     107516091 (PRKCB)    05161 Hepatitis B     107516091 (PRKCB)    05171 Coronavirus disease - COVID-19     107516091 (PRKCB)    05164 Influenza A     107516091 (PRKCB)    05163 Human cytomegalovirus infection     107516091 (PRKCB)   09174 Infectious disease: parasitic    05146 Amoebiasis     107516091 (PRKCB)    05140 Leishmaniasis     107516091 (PRKCB)    05143 African trypanosomiasis     107516091 (PRKCB)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     107516091 (PRKCB)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ray01001]     107516091 (PRKCB) Enzymes [BR:ray01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      107516091 (PRKCB) Protein kinases [BR:ray01001]  Serine/threonine kinases: AGC group   PKC family [OT]    107516091 (PRKCB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like C1_2 CEP76-C2 APH Motif Other DBs NCBI-GeneID:  107516091 NCBI-ProteinID:  XP_016010998 LinkDB All DBs Position Unknown AA seq 673 aa AA seqDB search MAEPAAGPPPGEGEEGAVRFARKGALRQKNVHEVKDHKFTARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRISIKAQIEKEVLTVVVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEAGECDDD LRQKFERAKIGQAPKTPEEKTTNATSKCDTNGSKDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHV KIADFGMCKENMWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHTVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDVKEHAFF RYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDHEVIRNIDQSEFEGFS FVNSEFLKPEVKS NT seq 2022 nt NT seq  +upstreamnt  +downstreamnt atggctgagccggccgcgggcccgccgccgggcgagggcgaggagggcgccgtgcgcttc gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaaggaccacaaattcacc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatctggggcttc gggaagcaaggatttcagtgccaagtctgctgtttcgtcgtgcacaagcggtgccatgag tttgtcaccttctcctgcccgggcgctgacaagggccccgcctccgacgacccccggagc aaacacaagttcaagatccacacgtactccagccccacgttctgcgaccactgcgggtcc ctgctgtacgggctcatccaccagggcatgaaatgcgacacctgcatgatgaacgtgcac aaacgctgcgtgatgaacgtgccgagcctctgcggcacggaccacacggagcgccgcggc cgcatctccatcaaggcacagatcgagaaggaagtgctcaccgtggtcgtgagagacgct aaaaacctcgtccccatggaccccaacggcttgtcagacccctacgtgaagctgaaactc attcccgaccccaaaagcgagagcaagcagaagaccaaaaccatcaagtgctccctgaac cccgagtggaacgagaccttcagattccagctgaaggaatcggacaaggaccggaggctg tccgtggagatctgggactgggacctgaccagccggaacgacttcatggggtccttgtcg ttcgggatctccgagctgcagaaggccggcgtcgacggctggttcaagctgctgagccag gaggagggcgagtacttcaacgtgccggtgccgcccgaggccggcgagtgcgacgacgac ctgcgccagaagttcgagagggccaagatcggtcaggcgcccaagaccccggaggagaag acgaccaatgccacctccaagtgcgacaccaacggcagcaaggaccggatgaagctgacc gacttcaacttcctgatggtgctgggcaagggcagcttcggcaaggtcatgctctcagag cggaagggcacggacgagctgtacgccgtcaagatcctgaagaaggacgtggtgatccag gacgacgacgtggagtgcacgatggtggagaagcgcgtgctcgcgctgcccgggaagccg cccttcctcacacagctgcactcctgcttccagaccatggaccgcctgtacttcgtgatg gagtatgtgaacggcggggacctcatgtaccacatccagcaggtcggccggttcaaggag cctcacgccgtattctacgccgcagaaatcgccatcgggctgttcttcctgcagagcaag ggcatcatttaccgcgacctgaaactcgacaacgtgatgctggactctgagggccacgtg aagatcgccgacttcggcatgtgcaaggagaacatgtgggacggggtgaccaccaagacc ttctgcggcaccccggactacatcgcccccgagatcatcgcttaccagccctacgggaag tcggtggactggtgggcgttcggcgtcctgctctacgaaatgctggccgggcaggcgccg ttcgaaggggaggacgaggacgagctcttccagtccatcatggagcacaccgtggcctac ccgaagtccatgtccaaggaggccgtggccatctgcaaagggctgatgaccaagcacccg ggcaagcgcctgggctgcgggcccgaaggcgagcgcgatgtcaaggagcatgcgttcttc cggtacatcgactgggagaagctggagcgcaaggagatccagccgccgtacaagccgaaa gcctgtgggcgaaacgccgaaaacttcgaccggtttttcacccgccaccctccagtccta actcctcccgaccacgaagtcatcaggaacattgaccaatcagaatttgaaggattttcc tttgttaactctgagtttctaaaacccgaagtcaagagctga

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