Rousettus aegyptiacus (Egyptian rousette): 107507294
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Entry
107507294 CDS
T06036
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521
EGFR tyrosine kinase inhibitor resistance
ray04062
Chemokine signaling pathway
ray04148
Efferocytosis
ray04151
PI3K-Akt signaling pathway
ray04217
Necroptosis
ray04550
Signaling pathways regulating pluripotency of stem cells
ray04630
JAK-STAT signaling pathway
ray04658
Th1 and Th2 cell differentiation
ray04659
Th17 cell differentiation
ray04725
Cholinergic synapse
ray04917
Prolactin signaling pathway
ray04920
Adipocytokine signaling pathway
ray04933
AGE-RAGE signaling pathway in diabetic complications
ray04935
Growth hormone synthesis, secretion and action
ray05140
Leishmaniasis
ray05145
Toxoplasmosis
ray05152
Tuberculosis
ray05161
Hepatitis B
ray05164
Influenza A
ray05167
Kaposi sarcoma-associated herpesvirus infection
ray05168
Herpes simplex virus 1 infection
ray05200
Pathways in cancer
ray05207
Chemical carcinogenesis - receptor activation
ray05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ray05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107507294 (JAK2)
04151 PI3K-Akt signaling pathway
107507294 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
107507294 (JAK2)
09143 Cell growth and death
04217 Necroptosis
107507294 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
107507294 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
107507294 (JAK2)
04659 Th17 cell differentiation
107507294 (JAK2)
04062 Chemokine signaling pathway
107507294 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
107507294 (JAK2)
04917 Prolactin signaling pathway
107507294 (JAK2)
04935 Growth hormone synthesis, secretion and action
107507294 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
107507294 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107507294 (JAK2)
05207 Chemical carcinogenesis - receptor activation
107507294 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
107507294 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
107507294 (JAK2)
05164 Influenza A
107507294 (JAK2)
05168 Herpes simplex virus 1 infection
107507294 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
107507294 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
107507294 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107507294 (JAK2)
05140 Leishmaniasis
107507294 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
107507294 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
107507294 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107507294 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ray01001
]
107507294 (JAK2)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107507294 (JAK2)
Protein kinases [BR:
ray01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107507294 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
107507294
NCBI-ProteinID:
XP_015993839
LinkDB
All DBs
Position
Unknown
AA seq
1132 aa
AA seq
DB search
MEMACLTMTEMEGTSMSPVHQNGDIPGNANSVKQIDPVLQVYLYHSLGKTEGDYLKFPSG
EYVAEEICVAASKACGITPVYHNMFALMNETERMWYPPNHVFHVDDSARHNVLYRIRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQEYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESDTLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKNLEVELNSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQT
GLYVLRCNPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLSGTKKNFSNLKDLLNC
YQMETVRSDNIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLLRHNNVNQMVFHKI
RNEDLIFNESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKILIHGNVCAKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKILNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYEDRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKDRIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRHLALRVDQIRDSMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atggaaatggcttgccttacaatgacggaaatggaaggaacatccatgtctcctgtacat
cagaatggtgatattcctggaaatgccaattctgtgaagcaaatagacccagttctacag
gtgtatctttatcattcccttgggaaaactgaaggcgattacctgaagtttccaagtggg
gagtatgttgcagaagaaatttgtgttgctgcttctaaagcctgtggaatcacacctgtg
tatcataatatgtttgctttaatgaatgaaacagaaaggatgtggtatccacccaaccat
gtcttccatgtagatgactcagccagacataatgtactctacagaataagattttacttt
ccttactggtattgtaatggcagcaacagaacctatcgacatggaatatctcgaggtgct
gaagctcctcttcttgacgactttgtcatgtcatacctttttgctcagtggcgtcatgat
tttttgcatggatggataaaagtacctgtgactcatgaaacacaggaagaatgtcttggg
atggcagtgctagatatgatgagaatagctaaagaaaaggatcaaaccccactggacatc
tatagctctgtcagctacaagacattcttaccaaaatgtgttcgagcaaagatccaagaa
tatcatattttgacaaggaagagaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgcattctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgatacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaagcaggcaaaccaggaaggctcaaatgaaagcaga
attgtcactatccataagcaagatggtaaaaatctggaagttgaacttaactcattaaga
gaagctttgtcttttgtgtcattaattgatggatattatagactaactgcagatgcacat
cattacctctgtaaagaagtagcacctccaacggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccatcagtaaactgaagaaagcaggtaatcagact
ggactctatgtacttcgatgcaatcctaaggactttaataaatattttttgacttttgct
gtagagcgagaaaatgtcattgaatataagcattgtttgattacaaaaaatgaaaatgga
gaatacaacctaagcgggactaagaagaacttcagtaatcttaaagatcttttgaattgc
taccagatggaaactgttcgctcagacaatataattttccagtttacgaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtctttagaaccaatggtatttctgatgta
ccaacctcaccaacattactgaggcataataatgtgaaccaaatggtttttcacaaaatt
agaaatgaagatttgatatttaatgaaagccttggccaaggcactttcacaaaaattttt
aaaggtgtaagaagagaagtgggagactatggtcaactgcatgaaacagaagtcctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagtatg
atgagccagctttctcacaagcatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtgaaatttggatcattagacacatatttgaaaaag
aataaaaattctatcaatatattatggaaacttgaagtggctaaacaattggcatgggcc
atgcattttctagaagaaaaaatccttattcatgggaatgtgtgcgccaaaaatattcta
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatccc
ggcattagtattacagttttgccaaaggacattcttcaagagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaattctaaacttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcctctcagtgctttggattctcaa
agaaaactacagttttatgaagataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattatgaaccagattttagaccttctttcagagcc
attatacgagatcttaatagtttgtttactccagattatgaactattaacagaaaatgac
atgttaccaaatatgaggataggtgccctggggttttctggtgcttttgaagaccgagac
cctacacagtttgaagagagacacttgaaatttctgcagcaactgggcaagggtaatttt
gggagtgtggagatgtgccggtatgaccctctacaagacaatactggggaggtggtggct
gtgaaaaagcttcagcacagtactgaagagcacctcagagattttgaaagggaaattgaa
atccttaaatctctacagcatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaacctaagattaattatggaatatttaccatatggaagtttacgagactat
cttcaaaagcataaagaccggatagatcataaaaaacttctgcagtacacatctcaaata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacaagg
aatatattggtggagaatgaaaacagagttaaaattggagattttgggttaaccaaagtc
ttgccacaagacaaagaatactataaagtgaaagaacctggcgaaagtcccatattctgg
tatgctccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtagttctgtatgaacttttcacatatattgagaagagtaaaagtcctccagcggaa
ttcatgcgtatgattggcaatgacaaacaagggcagatgattgtatttcatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgta
atcatgacagaatgctggaacaataatgtaaatcaacgcccctctttcagacacctcgct
cttcgagttgatcaaataagggacagcatggctggataa
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integrated database retrieval system
