Rousettus aegyptiacus (Egyptian rousette): 107508222
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Entry
107508222 CDS
T06036
Gene name
TBK1
Definition
(RefSeq) serine/threonine-protein kinase TBK1 isoform X1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04014
Ras signaling pathway
ray04137
Mitophagy - animal
ray04140
Autophagy - animal
ray04620
Toll-like receptor signaling pathway
ray04621
NOD-like receptor signaling pathway
ray04622
RIG-I-like receptor signaling pathway
ray04623
Cytosolic DNA-sensing pathway
ray04657
IL-17 signaling pathway
ray05014
Amyotrophic lateral sclerosis
ray05022
Pathways of neurodegeneration - multiple diseases
ray05135
Yersinia infection
ray05160
Hepatitis C
ray05161
Hepatitis B
ray05162
Measles
ray05163
Human cytomegalovirus infection
ray05164
Influenza A
ray05165
Human papillomavirus infection
ray05167
Kaposi sarcoma-associated herpesvirus infection
ray05168
Herpes simplex virus 1 infection
ray05169
Epstein-Barr virus infection
ray05170
Human immunodeficiency virus 1 infection
ray05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
107508222 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
107508222 (TBK1)
04137 Mitophagy - animal
107508222 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
107508222 (TBK1)
04621 NOD-like receptor signaling pathway
107508222 (TBK1)
04622 RIG-I-like receptor signaling pathway
107508222 (TBK1)
04623 Cytosolic DNA-sensing pathway
107508222 (TBK1)
04657 IL-17 signaling pathway
107508222 (TBK1)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
107508222 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
107508222 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
107508222 (TBK1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
107508222 (TBK1)
05161 Hepatitis B
107508222 (TBK1)
05160 Hepatitis C
107508222 (TBK1)
05171 Coronavirus disease - COVID-19
107508222 (TBK1)
05164 Influenza A
107508222 (TBK1)
05162 Measles
107508222 (TBK1)
05168 Herpes simplex virus 1 infection
107508222 (TBK1)
05163 Human cytomegalovirus infection
107508222 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
107508222 (TBK1)
05169 Epstein-Barr virus infection
107508222 (TBK1)
05165 Human papillomavirus infection
107508222 (TBK1)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
107508222 (TBK1)
Protein kinases [BR:
ray01001
]
Serine/threonine kinases: Other
IKK family [OT]
107508222 (TBK1)
Membrane trafficking [BR:
ray04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
107508222 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
Kinase-like
DUF713
CEP63
ubiquitin
Motif
Other DBs
NCBI-GeneID:
107508222
NCBI-ProteinID:
XP_015995388
LinkDB
All DBs
Position
Unknown
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSQEPLNTIGLTYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDHNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELDEISDIHTKLLRLSSSQGTIETNLQDIESRLSPGGLLADTWAHQE
GTHPKDRHVEKLQVLLNYITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLIKSEEWVRKMLHLRKQLLSLANQCLDIEEEVSKYQDYTNELQETLPQ
KMIAASSGIKHAMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLHNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcgaatgtctttcgtggaagacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttccttcgcccagtagatgttcaaatgagagaattcgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtccttattatggaattttgtccatgtgggagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagagaacggcatagtgcatcgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtactaagaaaagatcaccagaagaaatacggagca
acagttgatctttggagcattggggtaacgttttaccatgcagctaccggatcactgccg
tttagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccatctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctgtttcttgtagtctttctcggggtcttcaagttctacttactcctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcgctgcaacaaatgaca
gctcacaagatttatattcatagttataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgaaggacgacgcttagtt
cttgaacctggaagactggcacagcatttccctaaaactactgaggaaaaccctatcttt
gtagtaagccaggaacccctaaataccataggactgacatatgaaaaaatctcccttcct
aaagtacatccacgttatgatttagatggagatgctagcatggctaaggcaataacaggc
gttgtgtgttatgcctgtagaattgccagtaccctgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagttaaagatgatcataatgaaactgttcacaaa
aagacagaagttgtgatcacattggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatatgaaaagttgatgaaaatcaacctagaagcagcagagttagatgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccaatcttcag
gatatcgaaagcagattatctccaggtggattgctggctgatacatgggcccatcaagaa
ggcactcatcccaaagataggcatgtggaaaagctacaggtcctgttaaattacatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactggcttataatgaagaa
cagatccacaaatttgataagcaaaaactctattaccatgcaacaaaagctatgacccac
tttacagatgaatgtgttaaaaagtatgaggcatttttgattaagtcagaagaatgggtg
agaaagatgcttcatcttaggaaacagttattatccctagctaatcagtgtttggatatt
gaagaagaagtatcaaagtatcaagactatactaatgagttacaagaaactttgcctcag
aaaatgattgcagcctccagtggaatcaaacatgccatgactccaatttatccatgttcc
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggtt
gttaaagaacttgctgaaaataaccatattttagaaaggtttggctccttaaccatggat
ggtggccttcacaatgttgactgcctttag
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