KEGG   Rousettus aegyptiacus (Egyptian rousette): 107508791
Entry
107508791         CDS       T06036                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04060  Cytokine-cytokine receptor interaction
ray04068  FoxO signaling pathway
ray04144  Endocytosis
ray04218  Cellular senescence
ray04350  TGF-beta signaling pathway
ray04380  Osteoclast differentiation
ray04390  Hippo signaling pathway
ray04520  Adherens junction
ray04659  Th17 cell differentiation
ray04926  Relaxin signaling pathway
ray04933  AGE-RAGE signaling pathway in diabetic complications
ray05142  Chagas disease
ray05161  Hepatitis B
ray05166  Human T-cell leukemia virus 1 infection
ray05200  Pathways in cancer
ray05202  Transcriptional misregulation in cancer
ray05210  Colorectal cancer
ray05212  Pancreatic cancer
ray05220  Chronic myeloid leukemia
ray05225  Hepatocellular carcinoma
ray05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107508791 (TGFBR2)
   04350 TGF-beta signaling pathway
    107508791 (TGFBR2)
   04390 Hippo signaling pathway
    107508791 (TGFBR2)
   04068 FoxO signaling pathway
    107508791 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    107508791 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    107508791 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    107508791 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    107508791 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    107508791 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    107508791 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    107508791 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107508791 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    107508791 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    107508791 (TGFBR2)
   05212 Pancreatic cancer
    107508791 (TGFBR2)
   05225 Hepatocellular carcinoma
    107508791 (TGFBR2)
   05226 Gastric cancer
    107508791 (TGFBR2)
   05220 Chronic myeloid leukemia
    107508791 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    107508791 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    107508791 (TGFBR2)
   05161 Hepatitis B
    107508791 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    107508791 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ray01001]
    107508791 (TGFBR2)
Enzymes [BR:ray01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     107508791 (TGFBR2)
Protein kinases [BR:ray01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   107508791 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH
Other DBs
NCBI-GeneID: 107508791
NCBI-ProteinID: XP_015996276
LinkDB
Position
Unknown
AA seq 567 aa
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMTVTDSNGAVRFSQLCKFCDVRSTT
CDNQKSCMSNCSITSICEKPHEVCVAVWRKNDENITLETVCHDPKLVYHGFVLEDAASPK
CIMKEKKMDGETFFMCSCNTEECNDYIIFSEEYSTNNPDLWLVIFQVTGVSLLPPLGIAI
AVIITFYCYRVHRKQKLTSSWETNKPRKLMEFSEHLAIIMEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKMEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTLCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSSWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFDE
LEHLDRLSGRSCSEEKIPEDGSLSTTK
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcctctggacgcgcatc
gccagcacgatcccgccacacgttcagaagtcggttaataatgacatgacggtcactgac
agcaatggtgcagtcaggttttcacagttgtgtaaattttgtgatgtaagatctaccacc
tgtgacaaccagaaatcctgcatgagcaactgcagtatcacgtccatctgtgagaagcca
cacgaagtctgtgtggccgtctggagaaagaatgatgagaacataacactagagaccgtt
tgccatgaccccaagctcgtctaccacggatttgttcttgaggatgctgcttctccaaag
tgtattatgaaagaaaaaaaaatggatggcgagactttctttatgtgttcctgtaacact
gaggagtgcaatgactacatcatcttctcagaagaatattccaccaataaccctgacttg
tggttagtcatattccaagtgacaggcgtcagcctcctcccaccactgggcattgccata
gccgtcatcatcaccttctactgctaccgtgttcaccggaagcagaagctgacctcgtcc
tgggagaccaacaagccacggaagctcatggagttcagcgaacatcttgccatcattatg
gaagatgaccgctccgacatcagctccacgtgcgccaacaacatcaaccacaacacggag
ctgctgcccattgagctggacaccctggtgggcaaaggtcgcttcgccgaggtctacaag
gccaagctgaagcagaacacttcggagcagttcgagactgtggcggtcaagatcttccct
tatgaggagtatgcctcctggaagatggagaaggacattttctcagatatcaacctgaag
catgagaacatcctccagttcctgacggctgaagaacggaaaacggagttggggaagcaa
tattggctgatcacggctttccatgccaagggcaacctacaggagtatctcacacggcat
gtcatcagctgggaggacctgcgcaagctgggaagctccctggcccggggcattgctcac
ctgcacagcgaccacaccctgtgtgggagacccaagatgcccatcgtgcacagggacctc
aagagctccaatatcctggtgaaaaacgacctgacctgctgcctgtgtgactttggtctt
tccctgcgtctggatcccactctgtctgtggatgacttggccaacagtgggcaggtggga
actgccagatacatggccccagaagtcctcgagtccaggatgaacttggagaatgttgag
tccttcaagcagacagatgtctactcaatggcgcttgtgctctgggagatgacatctcgc
tgcaatgctgtgggagaggtgaaagattatgagccgccatttggttccaaggtgcgggag
catccctgtgtcgaaagcatgaaggacaatgtgttgcgagatcggggacgaccagaaatt
cccagctcctggctcaaccaccagggcatccagatggtgtgtgagactctgaccgagtgc
tgggaccacgaccctgaggcccgcctcacggcccagtgtgtggctgagcgcttcgacgag
ctggagcacctggaccgactctcggggaggagctgctccgaggagaagattccggaagac
ggctcgctgagcactaccaaatag

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