KEGG   Rousettus aegyptiacus (Egyptian rousette): 107508819
Entry
107508819         CDS       T06036                                 

Gene name
EGF
Definition
(RefSeq) pro-epidermal growth factor isoform X1
  KO
K04357  epidermal growth factor
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521  EGFR tyrosine kinase inhibitor resistance
ray04010  MAPK signaling pathway
ray04012  ErbB signaling pathway
ray04014  Ras signaling pathway
ray04015  Rap1 signaling pathway
ray04020  Calcium signaling pathway
ray04066  HIF-1 signaling pathway
ray04068  FoxO signaling pathway
ray04072  Phospholipase D signaling pathway
ray04151  PI3K-Akt signaling pathway
ray04510  Focal adhesion
ray04540  Gap junction
ray04630  JAK-STAT signaling pathway
ray04810  Regulation of actin cytoskeleton
ray05160  Hepatitis C
ray05165  Human papillomavirus infection
ray05200  Pathways in cancer
ray05210  Colorectal cancer
ray05212  Pancreatic cancer
ray05213  Endometrial cancer
ray05214  Glioma
ray05215  Prostate cancer
ray05218  Melanoma
ray05219  Bladder cancer
ray05223  Non-small cell lung cancer
ray05224  Breast cancer
ray05226  Gastric cancer
ray05231  Choline metabolism in cancer
ray05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107508819 (EGF)
   04012 ErbB signaling pathway
    107508819 (EGF)
   04014 Ras signaling pathway
    107508819 (EGF)
   04015 Rap1 signaling pathway
    107508819 (EGF)
   04630 JAK-STAT signaling pathway
    107508819 (EGF)
   04066 HIF-1 signaling pathway
    107508819 (EGF)
   04068 FoxO signaling pathway
    107508819 (EGF)
   04020 Calcium signaling pathway
    107508819 (EGF)
   04072 Phospholipase D signaling pathway
    107508819 (EGF)
   04151 PI3K-Akt signaling pathway
    107508819 (EGF)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    107508819 (EGF)
   04540 Gap junction
    107508819 (EGF)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    107508819 (EGF)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107508819 (EGF)
   05231 Choline metabolism in cancer
    107508819 (EGF)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107508819 (EGF)
  09162 Cancer: specific types
   05210 Colorectal cancer
    107508819 (EGF)
   05212 Pancreatic cancer
    107508819 (EGF)
   05226 Gastric cancer
    107508819 (EGF)
   05214 Glioma
    107508819 (EGF)
   05218 Melanoma
    107508819 (EGF)
   05219 Bladder cancer
    107508819 (EGF)
   05215 Prostate cancer
    107508819 (EGF)
   05213 Endometrial cancer
    107508819 (EGF)
   05224 Breast cancer
    107508819 (EGF)
   05223 Non-small cell lung cancer
    107508819 (EGF)
  09172 Infectious disease: viral
   05160 Hepatitis C
    107508819 (EGF)
   05165 Human papillomavirus infection
    107508819 (EGF)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107508819 (EGF)
Cytokines and growth factors [BR:ray04052]
 Growth factors
  Growth factors (RTK binding)
   107508819 (EGF)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition cEGF EGF_CA DUF5050 EGF EGF_3 Tr-sialidase_C
Other DBs
NCBI-GeneID: 107508819
NCBI-ProteinID: XP_015996313
LinkDB
Position
Unknown
AA seq 1124 aa
MLLFLVILLPVVFKSGFVSLSALPRWNCPEESPSGNGNPACVGPAPFLIFSHGNSIFRID
LEGTNYEKLVTDAGVSVIMDFHYNKERIYWVDLERQLLQRVFLNGTRQERVCNIEKNVSG
MAINWINEELIWSNQQEGIITITDMKGNNSRVLLSALKYPANVAVDPVERFIFWSSEVAG
SLQRTDLSGVEVKILVETAEKITAMSLDVLDKRLFWVQYDREGSNSRICSCDYDGGSVHF
SKYLSQHNLFSISLFGDRIFYSTWRKKTIWIANKHTGKDIVRINLNASFVPPGGIKVVHL
IGQPRAEDDAWASDQNFCRLRKGNCRGSVCGQDLKSHSCTCAEGYALSQDGKYCEDVNEC
AFWNHGCTLGCENIPGSYYCTCPVGFVLLPDGKRCHQLISCPSNASECSHECVLTSDGPI
CFCPEGSVLGTDGKTCSGCSSPDNGGCSQLCIPLSPVSWECGCYPGYDLRLDKKSCAASG
PQPFLLFANSQDIRHMHFDGTDYGTLLSKQMGTVFAIDHDPVENKVYFAHTALKCIERAN
MDGSQRERLIEEAIDVPEGLAIDWINRKLYWTDRGKSVIEGSDLSGKHREIIIKEDISRP
RGIAVHPVAKRLFWTDMGINPRIESSSLQGFGRLVIASSELVWPSGITIDFLTDKLYWCD
AKQSVIEMANLDGSKRQRLAQNDVGRPFAVAVFEDYIWFSDWTVPSVIRVNKRTGKNRVR
LRGSMLKPSSLVVVHPLAKPGADPCLYRNGGCEHICKEKFGTVQCSCREGFVKAPDGKLC
LALNGHQIAAGSGTDLSNQVKPSDILLSSQGFEDNITESQHVLVSEIMASDDDDCGPMGC
GAHSQCVSEGEVATCQCLKGFAGDGKLCSDIDECEMDVTVCPHPSSKCINTEGGHVCQCS
QGYQGDGIHCLDIDECQLGMHTCGENATCTNAEGNYTCLCAGIPSEPGRICPDSTPPSHL
REDGHYSVRNSYSECPPSHAGYCLHDGVCMYIEAVDNYACNCIVGYVGERCQHRDLKWWE
LRHAGHGRQRSLAVGAVCVLVLVLLLLLGLWGAHCYRTQKLLSKNQKSPYEESCRDPSIS
RPADGEARVSSCPQPWFVVIKEHENLRNGDPPVAPRDGQAAVAD
NT seq 3375 nt   +upstreamnt  +downstreamnt
atgctgctcttccttgtcattctgttgccggtagtttttaagtctggttttgttagtctc
tcagcactgcctcgctggaactgtcctgaagagtctccctctggaaatgggaatcctgct
tgtgtgggtcctgcacccttcttaattttctctcatggaaatagtatctttaggattgac
ctggaaggaactaattatgagaaattggtgacagatgctggcgtatcagtgatcatggat
tttcattacaataaggaaagaatctattgggtagatctagaaagacaacttttgcaaaga
gtttttctgaatgggacaaggcaagagagagtatgcaatatagagaaaaatgtttcagga
atggcaataaattggataaatgaagaacttatttggtcaaatcaacaggaaggaatcatt
acaataacagatatgaaaggaaacaattcccgtgttctcttaagtgccttaaaatatcct
gcaaatgtagcggttgatccagtagaaaggtttatattttggtcttcagaggtggccggc
agccttcagaggacagatctcagtggtgtggaagtgaagattctggtagagacggcagag
aaaataacagctatgtcgttggatgtgcttgataaacggctcttttgggttcagtatgac
agagaaggaagcaattctcgtatttgttcctgtgattatgatggaggttctgtccatttt
agtaaatatctttcacagcacaatttgttttcaatatccctttttggtgaccgaatcttc
tattcaacatggagaaagaagacaatttggatagctaacaaacacactgggaaggatata
gttcgaattaacctcaatgcatcatttgtaccacctggaggaattaaagtagtgcacctg
atcggacagcccagggcagaggatgatgcttgggcatctgatcagaacttctgcagactg
aggaaaggcaactgcagaggcagcgtgtgtgggcaagaccttaagtcccattcgtgcacg
tgtgcggagggatatgctttaagccaggacggaaagtattgtgaagatgttaatgaatgt
gctttttggaaccatggctgcactcttggatgcgaaaacatccctggatcctattattgc
acatgccctgtaggatttgttctgcttcctgatggaaaacggtgtcaccaattaatttcc
tgtccaagcaatgcatctgaatgcagccatgagtgcgttctgacttcagatggtcccata
tgtttctgtcctgaaggttcagtgcttgggacagatggaaaaacgtgtagtggctgttca
tcacctgataatggtggatgtagccagctctgcatccctctcagcccagtatcctgggaa
tgtggttgctaccctggttatgacctacgactggacaaaaaaagctgtgcagcttcagga
ccacaaccatttttgctgtttgccaattctcaagatattcgacacatgcattttgatgga
acagattatggaaccctgctcagcaagcaaatgggaacggttttcgccatagatcatgac
cctgtggaaaataaggtatactttgcccatacagccctcaagtgcatagagagagcaaat
atggatggttcccagagagaaaggcttatcgaggaagcaatagatgtgccagaaggtctt
gctatagactggatcaatcgtaaactctattggacagacagagggaaatcggtcattgaa
ggcagtgatttaagtggaaaacatcgtgaaataatcattaaggaagacatctctcggcca
cgaggaattgctgtccatccagtggccaagagattattctggactgatatgggaattaat
ccacgaattgaaagttcttccctccaaggctttggccgactggtcatcgctagctctgag
ctggtctggcccagtggaataacgattgacttcctaaccgacaagttgtattggtgcgat
gccaagcaatctgtgattgaaatggctaatctggatggttcgaaacgccaaagacttgcc
cagaacgatgtaggtcgcccctttgctgtggctgtgtttgaggattacatctggttctcc
gactggactgtgccctcggtaataagagtgaacaagaggactggcaaaaacagggtacgt
ctccgaggcagcatgctgaagccctcatcactggttgtagttcatccattggcaaaacca
ggagcagatccctgcttatatcgaaatggaggctgtgaacatatttgcaaagagaagttt
ggaactgttcagtgttcgtgtcgtgaaggttttgtgaaagccccagatgggaaactgtgt
ctggccctaaatggtcatcagatagcggcaggtagtggaacagatctaagtaatcaagta
aaaccatcggacatcttactcagcagtcaagggtttgaagataatattacagaatcgcaa
catgtgctagtgtctgaaatcatggcatcagatgatgacgactgtggtcccatggggtgt
ggtgcacactctcagtgtgtttcagagggagaggtggccacgtgtcagtgtttgaaagga
tttgctggggatggaaaattatgttctgatatagatgaatgtgagatggatgttacagtt
tgcccgcacccctcctccaagtgcatcaatactgaaggtggccatgtctgccagtgctca
caaggctaccaaggagacggaattcactgtctcgatattgatgagtgccaactgggcatg
cacacctgtggggaaaatgccacctgtacaaacgcagagggaaactacacctgcctgtgt
gccggcatcccgtctgaacctggacggatttgccctgactccactccaccctctcatctc
agggaagatggtcactattctgtgaggaatagttactccgaatgtcccccgtcccacgct
gggtactgcctccacgacggtgtgtgcatgtacattgaagccgtggacaactacgcatgc
aactgtattgttggctacgtcggggagcgatgtcagcaccgagacttgaaatggtgggaa
ctgcgccacgctggccacgggcggcagcggagcctggcggtgggggccgtctgcgtcctg
gtgctcgtcctgctgctgctcctggggctgtggggcgcgcactgctacaggactcagaag
ctgctatcaaaaaatcagaagagcccttacgaagagtcatgcagagatccgagcatcagc
aggcctgcagacggagaggccagggtgtcctcctgtccccagccttggtttgtggttata
aaggaacacgagaacctcaggaatggggatccacccgtggctccccgggatggccaggcc
gcagttgctgactag

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