Rousettus aegyptiacus (Egyptian rousette): 107512383
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Entry
107512383 CDS
T06036
Gene name
GCK
Definition
(RefSeq) glucokinase isoform X1
KO
K12407
glucokinase [EC:
2.7.1.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00010
Glycolysis / Gluconeogenesis
ray00052
Galactose metabolism
ray00500
Starch and sucrose metabolism
ray00520
Amino sugar and nucleotide sugar metabolism
ray00524
Neomycin, kanamycin and gentamicin biosynthesis
ray01100
Metabolic pathways
ray01200
Carbon metabolism
ray04910
Insulin signaling pathway
ray04911
Insulin secretion
ray04917
Prolactin signaling pathway
ray04922
Glucagon signaling pathway
ray04930
Type II diabetes mellitus
ray04950
Maturity onset diabetes of the young
ray05230
Central carbon metabolism in cancer
Module
ray_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
ray_M00549
Nucleotide sugar biosynthesis, glucose => UDP-glucose
ray_M00892
UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
107512383 (GCK)
00052 Galactose metabolism
107512383 (GCK)
00500 Starch and sucrose metabolism
107512383 (GCK)
00520 Amino sugar and nucleotide sugar metabolism
107512383 (GCK)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
107512383 (GCK)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
107512383 (GCK)
04910 Insulin signaling pathway
107512383 (GCK)
04922 Glucagon signaling pathway
107512383 (GCK)
04917 Prolactin signaling pathway
107512383 (GCK)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
107512383 (GCK)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
107512383 (GCK)
04950 Maturity onset diabetes of the young
107512383 (GCK)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.2 glucokinase
107512383 (GCK)
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SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
Motif
Other DBs
NCBI-GeneID:
107512383
NCBI-ProteinID:
XP_016003340
LinkDB
All DBs
Position
Unknown
AA seq
601 aa
AA seq
DB search
MVSCRDVTFPKQRETQTSSEPALCPIAGRESEQETGQRGQHAHSPRPGPGGVGSSSRWPG
SSPFGIIPTSYVVPFCVKQRGQHKHRASSAPGSAVDVRRKQPARVRAPQLQAVRRAKPRQ
GPRLPVTGALAGVWMGNRAQRGHRRPPGRSEAEQILAEFRLQEEDLKKVMRRMQKEMDRG
LRLATHEEASVKMLPTYVRSTPEGSEVGDFLSLDLGGTNFRVMLVKVGEGEAGQWSLNTK
HQMYSIPEDAMTGTAEMLFDYVSECISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKGIL
LNWTKGFKASGAEGNNVVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRQCEVGM
IVGTGCNACYMEEMHNVELVDGDEGRMCVNTEWGAFGDAGELDEFLLEYDRMVDESSLNP
GQQLYEKLISGKYMGELVRLVLLKLVDEDLLFRGEASEQLRTRGAFETRFVSQVESDSGD
RKQIYNILSTLGLRPSATDCDIVRRACESVSTRAAHMCGAGLAGVINRMRESRSEDVMRI
TVGVDGSVYKLHPSFKERFHAIVRRLTPSCEITFIQSEEGSGRGAALVSAVASKKACMLG
Q
NT seq
1806 nt
NT seq
+upstream
nt +downstream
nt
atggtgagctgcagagatgttacctttccaaaacaaagagaaacccagacatcatctgag
ccagccctgtgccctatagcaggcagggagagtgagcaggagacagggcagaggggacag
catgcccacagccccaggccagggccaggtggagtgggcagctcaagcaggtggccgggg
tccagtccctttggcataattcccacctcatacgtcgtgcctttctgtgtgaaacaacga
ggtcagcacaaacaccgggctagttccgctcccggtagtgccgttgatgtcaggaggaag
cagccagcccgggtcagggcgccacagctgcaggcagtgaggcgggccaaaccccggcaa
ggcccacgtctgccagtcactggggctctggcgggagtttggatgggaaatcgtgcacaa
aggggccacaggaggccacctgggagaagcgaggccgagcagatcctggcggagttcagg
ctgcaggaggaggatctgaagaaggtgatgaggcggatgcagaaggagatggaccgaggc
ctgaggctggcgactcacgaggaggccagcgtgaagatgctgcccacctacgtgcgctcc
acccccgaaggctcagaagtcggggacttcctctccctggacctgggtggcaccaacttc
agggtgatgctggtgaaggtgggggagggcgaggcagggcagtggagcctgaacaccaag
caccagatgtactccatccccgaggacgccatgacgggcaccgccgagatgctcttcgac
tatgtctccgagtgcatctccgacttcctggacaagcaccagatgaagcacaagaagctg
cccttgggcttcaccttctccttccccgtgcggcacgaggacatcgacaagggcatcctt
ctcaactggaccaagggcttcaaggcttctggggcagaagggaacaacgttgtggggctc
ctgcgagacgccatcaagcggagaggggactttgagatggacgtggtggccatggtgaat
gacaccgtggccacaatgatctcctgctactacgaagaccgccagtgtgaggttggcatg
atagtgggcacgggctgcaacgcttgttacatggaggaaatgcacaacgtggagctggtg
gatggggacgagggccgcatgtgcgtcaacaccgagtggggggcctttggggacgcaggc
gagctggacgagttcctgctggagtacgaccggatggtggacgagagctcgctcaacccg
ggccagcagctgtatgagaagctcatcagcggcaagtacatgggcgagctggtgcggctc
gtgctgctcaagctggtggacgaggacctgctcttccgcggcgaggcctcggagcagctg
cgcacgcgcggcgccttcgagacccgcttcgtgtcgcaggtggagagcgactcaggcgac
cgcaagcagatctacaatatcctgagcacgctggggctgaggccctcggccactgactgc
gacatcgtgcgcagagcctgcgagagtgtgtccacgcgcgccgcgcacatgtgcggcgcg
gggctggcgggcgtcatcaaccgcatgcgcgagagccgcagcgaggacgtgatgcgcatc
accgtgggcgtggacggctcggtgtacaagttgcaccccagcttcaaggagcggttccat
gccattgtgcgcaggctgacccccagctgcgagatcaccttcatccagtcggaggagggc
agtggccggggcgcagctctggtctccgccgtcgcctctaagaaggcctgcatgctgggc
cagtga
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