Rousettus aegyptiacus (Egyptian rousette): 107512674
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Entry
107512674 CDS
T06036
Gene name
MDM2
Definition
(RefSeq) E3 ubiquitin-protein ligase Mdm2
KO
K06643
E3 ubiquitin-protein ligase Mdm2 [EC:
2.3.2.27
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01522
Endocrine resistance
ray01524
Platinum drug resistance
ray04068
FoxO signaling pathway
ray04110
Cell cycle
ray04115
p53 signaling pathway
ray04120
Ubiquitin mediated proteolysis
ray04144
Endocytosis
ray04151
PI3K-Akt signaling pathway
ray04218
Cellular senescence
ray04625
C-type lectin receptor signaling pathway
ray04919
Thyroid hormone signaling pathway
ray05163
Human cytomegalovirus infection
ray05165
Human papillomavirus infection
ray05169
Epstein-Barr virus infection
ray05200
Pathways in cancer
ray05202
Transcriptional misregulation in cancer
ray05203
Viral carcinogenesis
ray05205
Proteoglycans in cancer
ray05206
MicroRNAs in cancer
ray05214
Glioma
ray05215
Prostate cancer
ray05218
Melanoma
ray05219
Bladder cancer
ray05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
107512674 (MDM2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
107512674 (MDM2)
04151 PI3K-Akt signaling pathway
107512674 (MDM2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
107512674 (MDM2)
09143 Cell growth and death
04110 Cell cycle
107512674 (MDM2)
04115 p53 signaling pathway
107512674 (MDM2)
04218 Cellular senescence
107512674 (MDM2)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
107512674 (MDM2)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
107512674 (MDM2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107512674 (MDM2)
05202 Transcriptional misregulation in cancer
107512674 (MDM2)
05206 MicroRNAs in cancer
107512674 (MDM2)
05205 Proteoglycans in cancer
107512674 (MDM2)
05203 Viral carcinogenesis
107512674 (MDM2)
09162 Cancer: specific types
05214 Glioma
107512674 (MDM2)
05220 Chronic myeloid leukemia
107512674 (MDM2)
05218 Melanoma
107512674 (MDM2)
05219 Bladder cancer
107512674 (MDM2)
05215 Prostate cancer
107512674 (MDM2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
107512674 (MDM2)
05169 Epstein-Barr virus infection
107512674 (MDM2)
05165 Human papillomavirus infection
107512674 (MDM2)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
107512674 (MDM2)
01522 Endocrine resistance
107512674 (MDM2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ray04131
]
107512674 (MDM2)
04121 Ubiquitin system [BR:
ray04121
]
107512674 (MDM2)
Enzymes [BR:
ray01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
107512674 (MDM2)
Membrane trafficking [BR:
ray04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
107512674 (MDM2)
Ubiquitin system [BR:
ray04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
MDM2/MDM4 proteins
107512674 (MDM2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C3HC4_3
SWIB
zf-RanBP
zf-RING_2
DUF1229
zf-FPG_IleRS
Motif
Other DBs
NCBI-GeneID:
107512674
NCBI-ProteinID:
XP_016003948
LinkDB
All DBs
Position
Unknown
AA seq
492 aa
AA seq
DB search
MCNTSMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY
IMNKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQEPSDSGI
PVSENSCHLEGGSDEKDPVQELQEEKPSSSDSVSRPSPSSRRRTISETEDNSDELPGERQ
RKRHKSDSISFSFDENLALCVIREIRCERNSSSESTGTSSNPDLDAGVSEHSGDWLDQDS
VSDRFSVEFEVESFNSEDYNLSEEGQELSDEDDEVYQVTVYQAEESDTDSFEDDPEISLA
DYWKCTSCSEMNPPLPPHCNRCWALRENWLPEDKGKEKGKMAEETELENSVQVEEGFDVP
DCKKNTTVYDSRESCVEENDEKITQASQSQESEDYSQPSTSSSIIYSSQEDVKELEKEET
QDKEESVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCR
QPIQMIVLTYFS
NT seq
1479 nt
NT seq
+upstream
nt +downstream
nt
atgtgcaataccagcatgtctgtgtctactgatggtgctgtaagcacctcacagattcca
gcttcagaacaagagaccctggttagaccaaagccattacttttgaagttgttgaaatct
gttggtgcacaaaaagacacttacactatgaaagaggttatattttatcttggccagtat
attatgaataaacgattatatgatgagaagcaacagcatattgtatattgttcaaatgat
cttctaggggatttgtttggagtgccaagcttctctgtgaaagaacacaggaaaatatat
acaatgatctacagaaacttggtagtagtcaatcaacaggaaccatcagattcaggcata
cccgtgagtgaaaacagttgtcatcttgaaggtgggagtgatgaaaaggaccctgtgcaa
gagctacaagaagaaaaaccttcatcttcagattcggtttctagaccatctccctcatct
agaaggagaacaattagtgagacagaggacaattcagatgaactacctggtgaacgacaa
agaaagcgccacaaatctgatagtatttccttttcctttgatgaaaaccttgctctttgt
gtaataagggagatacgttgtgaaagaaacagtagcagtgaatcaacagggacttcatca
aatccggatcttgatgctggtgtaagtgaacattcaggtgattggttggatcaggattca
gtttcagatcgattcagtgtagaatttgaagttgagtctttcaattcagaagattataac
cttagtgaagaaggacaagaactctcagatgaagatgatgaggtatatcaagttactgtg
tatcaggcagaggagagtgatacagattcatttgaagacgaccctgaaatctccttagct
gactattggaagtgcacttcatgcagtgaaatgaatcctccccttccaccacattgcaac
agatgctgggcccttcgtgagaattggcttcctgaagacaaagggaaagaaaaagggaaa
atggctgaggaaactgaacttgaaaactcagtacaagtagaagagggctttgatgtccct
gattgtaaaaaaaatactacagtgtatgattcccgagaatcatgtgttgaggaaaatgat
gaaaagatcacacaagcctcccaatcccaagaaagtgaagactattctcagccatcaact
tctagtagcattatttatagcagccaagaagatgtcaaagagttagagaaggaagaaaca
caagacaaagaagaaagtgtggagtctagttttccacttaatgctatcgaaccttgtgtg
atttgccaaggtcgacctaaaaatggttgcatcgtccatggcaaaacaggacatcttatg
gcatgttttacgtgtgcaaagaagctaaagaaaaggaataagccctgcccagtgtgtaga
caaccaattcaaatgatcgtgttaacttatttctcctag
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