KEGG   Rousettus aegyptiacus (Egyptian rousette): 107513823
Entry
107513823         CDS       T06036                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3 isoform X1
  KO
K04692  signal transducer and activator of transcription 3
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521  EGFR tyrosine kinase inhibitor resistance
ray04062  Chemokine signaling pathway
ray04066  HIF-1 signaling pathway
ray04068  FoxO signaling pathway
ray04217  Necroptosis
ray04550  Signaling pathways regulating pluripotency of stem cells
ray04630  JAK-STAT signaling pathway
ray04659  Th17 cell differentiation
ray04917  Prolactin signaling pathway
ray04920  Adipocytokine signaling pathway
ray04931  Insulin resistance
ray04933  AGE-RAGE signaling pathway in diabetic complications
ray04935  Growth hormone synthesis, secretion and action
ray05145  Toxoplasmosis
ray05160  Hepatitis C
ray05161  Hepatitis B
ray05162  Measles
ray05163  Human cytomegalovirus infection
ray05167  Kaposi sarcoma-associated herpesvirus infection
ray05169  Epstein-Barr virus infection
ray05200  Pathways in cancer
ray05203  Viral carcinogenesis
ray05205  Proteoglycans in cancer
ray05206  MicroRNAs in cancer
ray05212  Pancreatic cancer
ray05221  Acute myeloid leukemia
ray05223  Non-small cell lung cancer
ray05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ray05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    107513823 (STAT3)
   04066 HIF-1 signaling pathway
    107513823 (STAT3)
   04068 FoxO signaling pathway
    107513823 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    107513823 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    107513823 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    107513823 (STAT3)
   04062 Chemokine signaling pathway
    107513823 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    107513823 (STAT3)
   04917 Prolactin signaling pathway
    107513823 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    107513823 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    107513823 (STAT3)
   05206 MicroRNAs in cancer
    107513823 (STAT3)
   05205 Proteoglycans in cancer
    107513823 (STAT3)
   05203 Viral carcinogenesis
    107513823 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    107513823 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    107513823 (STAT3)
   05221 Acute myeloid leukemia
    107513823 (STAT3)
   05223 Non-small cell lung cancer
    107513823 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    107513823 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    107513823 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    107513823 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    107513823 (STAT3)
   05161 Hepatitis B
    107513823 (STAT3)
   05160 Hepatitis C
    107513823 (STAT3)
   05163 Human cytomegalovirus infection
    107513823 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    107513823 (STAT3)
   05169 Epstein-Barr virus infection
    107513823 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    107513823 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    107513823 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:ray03000]
    107513823 (STAT3)
Transcription factors [BR:ray03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    107513823 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 E2R135 DUF4795 Syntaxin-6_N AP1AR Fib_alpha
Other DBs
NCBI-GeneID: 107513823
NCBI-ProteinID: XP_016006355
LinkDB
Position
Unknown
AA seq 770 aa
MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNL
LGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAA
TAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLK
SQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEEL
ADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQ
HRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNY
QLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGN
GGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWY
NMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYS
GCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILST
KPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIM
DATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADTGSAAPYLKTKFICVTPTTCSN
TIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2313 nt   +upstreamnt  +downstreamnt
atggcccaatggaatcagctacagcagctcgacacacgatacctggagcagcttcatcag
ctgtacagtgacagcttcccaatggagctgcggcagtttctggccccttggattgagagt
caagattgggcttatgcagccagcaaagaatcacatgccactttggtgtttcataacctc
ttgggtgagattgaccagcagtacagccgcttcctacaagaatcgaatgttctctatcag
cacaatctgcgaagaatcaagcaattccttcagagcaggtatcttgagaagccaatggag
attgcccggattgtggcccggtgcctgtgggaagagtctcgcctcctccaaactgcagcc
actgcagcccagcaagggggccaggccaaccaccctacagccgccgtggtgacagagaag
cagcagatgctggagcagcacctacaggatgttcggaagcgagtacaggatctagaacag
aaaatgaaagtggtagagaatctccaggatgactttgatttcaactataaaaccctcaag
agtcaaggagacatgcaggatctgaatggaaacaaccagtccgtgaccaggcagaagatg
cagcagctagaacagatgctaacagcgctggaccagatgcggcggagcatcgtgagtgag
ttggcggggcttttgtcagctatggagtatgtgcagaaaactctcacggatgaggagctg
gctgactggaagaggcggcaacagatcgcttgcattggaggccctcctaacatctgcctc
gatcgtcttgaaaactggataacctcattagcagagtctcaacttcagacccgccaacaa
attaagaaactggaggagttgcagcaaaaagtttcctacaaaggggatcccattgtacag
caccggccaatgctggaggagaggatcgtggagctgttcagaaacttaatgaaaagtgcc
ttcgtggtggagcggcagccctgcatgcccatgcatcccgaccggcccttagtcatcaag
accggtgtccagtttactactaaagtcagattgctggtcaaatttcctgagttaaattat
cagcttaaaattaaagtatgcattgacaaagattccggcgacgttgcagctctcagagga
tctcggaaatttaacattctgggcacaaacacgaaagtgatgaacatggaagaatccaac
aatggcagcctctccgcagagttcaaacacttgaccctgagagagcaaagatgtggtaac
gggggccgagccaactgtgatgcctccctgattgtgacggaggagctgcacctgatcacc
tttgagactgaagtgtatcaccaaggcctcaagattgacctagagacccactccttgcca
gtcgtggtgatctccaacatctgtcagatgccaaatgcctgggcatccatcctgtggtat
aacatgctgaccaacaatcccaagaacgtgaactttttcaccaagcccccaattggaacc
tgggatcaagtggccgaggtgctgagctggcagttctcctccaccacaaagcgggggctg
agcatcgagcagttgactacgctggcagagaagctcctaggacctggtgtgaattattca
ggatgtcagatcacatgggcaaaattttgcaaagaaaacatggctggcaagggcttttct
ttctgggtctggctggacaatatcattgaccttgtgaaaaagtacatcctggccctttgg
aatgaagggtacataatgggcttcatcagtaaggagagggagagagccatcttgagcacc
aagcccccaggcaccttcctgctgagattcagtgaaagcagcaaagaaggaggtgtcact
ttcacatgggtggagaaggacatcagcggtaagacacagatccagtcagtggagccatat
accaagcagcagctgaacaacatgtcatttgcggaaatcatcatgggctataagatcatg
gatgccaccaatatcctagtgtcgccgctggtctatctctaccctgacattcccaaggag
gaggcattcggaaagtactgtcggccagagagccaggagcatcctgaggctgacacaggt
agtgctgccccttacctgaagaccaagtttatctgtgtgacaccaacgacctgcagcaat
accattgacctgccgatgtccccccgcactttagattcattgatgcagtttggaaataat
ggtgaaggtgctgaaccctcagcaggagggcagtttgagtccctcacattcgacatggag
ctgacctcagagtgtgctacctcccccatgtga

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