KEGG   Rousettus aegyptiacus (Egyptian rousette): 107517636
Entry
107517636         CDS       T06036                                 

Gene name
ERBB4
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-4
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
ray  Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04010  MAPK signaling pathway
ray04012  ErbB signaling pathway
ray04020  Calcium signaling pathway
ray04151  PI3K-Akt signaling pathway
ray05014  Amyotrophic lateral sclerosis
ray05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ray00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    107517636 (ERBB4)
   04012 ErbB signaling pathway
    107517636 (ERBB4)
   04020 Calcium signaling pathway
    107517636 (ERBB4)
   04151 PI3K-Akt signaling pathway
    107517636 (ERBB4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    107517636 (ERBB4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    107517636 (ERBB4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ray01001]
    107517636 (ERBB4)
Enzymes [BR:ray01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     107517636 (ERBB4)
Protein kinases [BR:ray01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   107517636 (ERBB4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr GF_recep_IV Pkinase Furin-like Recep_L_domain Kinase-like APH DUF3951
Other DBs
NCBI-GeneID: 107517636
NCBI-ProteinID: XP_016014066
LinkDB
Position
Unknown
AA seq 1192 aa
QNLFVCFNTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHK
SCTGRCWGPTEHHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMN
FNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSS
KMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVT
GIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSG
LSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNR
KAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGRTCIESCNLYDGEFREFANGSI
CVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGTNSFIFKYADPD
RECHPCHPNCTQGCIGSSIEDCIGLMDRCSGPTSHDCIYYPWTGHSTLPQHARTPLIAAG
VIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKET
ELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMD
HPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEE
RRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRK
FTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKC
WMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDM
MDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFTAEQG
VPAPYRAPTSTIPEAPVAQGATAEIFDDSCCNGTLRKAVAPRVQEDSSTQRYSADPTVFA
PERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNAPNGPP
KAEDEYVNEPLYLNTFANALGNAEYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHP
DYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq 3579 nt   +upstreamnt  +downstreamnt
caaaatctgtttgtttgttttaatacagaaatcctcaatggtggagtctatgtagaccag
aacaaatttctttgttatgcagacacaattcattggcaagatattgttcggaatccatgg
ccttccaacttgactctggtgtcaacaaacggtagctcaggctgtggacgttgtcataag
tcctgtactggccgatgctggggacccacagaacatcattgccagactttgacaaggaca
gtgtgtgcagaacaatgtgatggcaggtgctacggaccctatgtcagtgactgctgtcat
cgagaatgtgccggaggctgctcaggacctaaagacactgactgctttgcctgcatgaat
ttcaatgacagtggagcttgtgttacgcaatgtccccaaacttttgtctacaatccaacc
acctttcaattggagcataacttcaatgcaaagtacacatatggagcattttgtgttaaa
aaatgcccacataactttgtggttgattctagttcttgtgtgcgtgcctgccctagttcc
aaaatggaagtagaagaaaatgggattaaaatgtgtaaaccttgcactgatatttgccca
aaagcttgtgacggcattggcacaggatcgttgatgtcagcacagactgtggattccagt
aacattgacaaattcataaactgcaccaaaatcaatgggaatttgatttttcttgtcact
ggtattcatggggacccttacaatgcaattgaagccatagatccagagaaactgaatgtc
tttcggactgtccgagagataacaggtttcttgaacatacagtcatggcccccgaacatg
actgacttcagtgttttttctaacctggtgaccattggtgggagagtactctacagtggc
ctctcattgctaatcctcaagcaacaaggcatcacttcactgcagttccagtctctgaag
gaaatcagtgcaggaaatatctatattactgacaacagcaacctatgttattatcatacc
attaactggactacactcttcagcactatcaaccaaagaatagtgatccgggacaacagg
aaagctgaaaactgtactgccgagggaatggtgtgtaatcatctgtgttcaaatgatggc
tgttggggacctgggccagaccagtgcctgtcgtgccgtcgcttcagcagaggaaggacc
tgcatagagtcctgtaacctctatgatggtgaatttcgggagtttgcgaatggttccatc
tgtgtggagtgtgacccccagtgtgagaagatggaagatggcatcctcacatgccatgga
ccgggacctgacaactgtacgaagtgctcccattttaaggatggcccgaactgtgtggaa
aaatgtccagatggcttacaggggacgaatagtttcatcttcaagtacgctgatcctgat
cgagagtgccacccgtgccacccaaactgcacacaagggtgcataggctcaagtattgaa
gactgcatcggcctgatggataggtgtagcggtcccactagtcatgactgcatttactac
ccttggacgggccattccactttaccacaacatgctagaactcctctaattgcagccgga
gtcattggagggcttttcatcctggtcatagtgggtctaacatttgcagtttatgtgaga
aggaagagcatcaaaaagaaaagagccttgagaagattcttggaaacagagttggtagaa
ccattaactcccagtggcacagcacccaatcaagctcaacttcgtattttgaaagaaact
gagctcaaaagagtgaaggtacttggctctggtgcttttggaaccgtctataaaggtatt
tgggtacctgaaggagaaacagtgaagattcctgtggctattaagattcttaatgagaca
actggtcccaaagccaatgtggagttcatggatgaagctctgatcatggcaagtatggat
catccacacttagtgaggttattgggtgtgtgtctgagcccaaccatccagctggtcaca
cagcttatgccccatggctgcctgttggattacgtccatgaacacaaggataacattgga
tcacagctgctgcttaactggtgtgtccagatagctaagggaatgatgtatctggaagaa
agacgtcttgttcatcgtgatttggcagctcgtaacgtcttagtgaaatctccaaaccat
gtgaaaatcacagattttggactagccagactcttggaaggagatgaaaaagagtataat
gctgatggaggaaagatgccaattaaatggatggctctggagtgtatacactacaggaaa
tttacccatcagagtgacgtttggagctacggagtcactatatgggaactgatgaccttt
ggaggaaaaccctatgatggaattccaacccgagaaatccctgacttattagagaaagga
gaacgtttgccccagcctcctatctgcactattgacgtttacatggtcatggtcaaatgt
tggatgattgatgctgacagtagacctaaatttaaggaactggctgctgaattttccagg
atggctcgagaccctcaaagatatctagttattcagggtgatgatcgtatgaagcttccc
agtccaaacgacagcaagttctttcagaatctcttggatgaagaggatttagaagatatg
atggatgctgaggaatacctggtccctcaggctttcaacatcccacctcccatctatact
tcaagagcaagaattgactcaaataggagtgaaattggacacagccctcctcccgcctac
acccccatgtcaggaaaccagtttgtataccgagatggaggtttcactgcagaacaagga
gtgcccgcaccctacagagccccaaccagcaccatcccagaagctccagttgctcaggga
gctacagcggaaatttttgatgactcctgttgcaatggcaccttacgcaaggcagtggca
ccccgcgtccaagaggatagcagcacccagaggtacagcgctgaccccacagtgtttgcc
ccagaacggagcccacgaggagagctggatgaagaaggttacatgacccctatgcgagac
aaacctaaacaagaatatctgaaccctgtggaagagaacccctttgtttctcggagaaaa
aacggagaccttcaagctttggataatcccgaatatcacaatgctcccaatggtccaccc
aaggcagaagatgagtacgtgaatgagccactgtacctcaacacctttgccaatgccttg
gggaatgccgagtacctgaagaacaatgtactgtctgtaccagagaaggccaagaaagcg
ttcgacaaccctgactactggaaccacagcctgccacctcggagcacccttcagcaccca
gactacctgcaggagtacagcacaaaatatttttataaacaaaatggacggatccggcct
attgtggcagagaatcctgaatacctctctgagttctcactgaagccaggcactgtgctg
cctcctccaccctacagacaccgaaatactgtggtgtaa

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