Rousettus aegyptiacus (Egyptian rousette): 107517940
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Entry
107517940 CDS
T06036
Gene name
JAK1
Definition
(RefSeq) tyrosine-protein kinase JAK1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521
EGFR tyrosine kinase inhibitor resistance
ray04151
PI3K-Akt signaling pathway
ray04217
Necroptosis
ray04380
Osteoclast differentiation
ray04550
Signaling pathways regulating pluripotency of stem cells
ray04621
NOD-like receptor signaling pathway
ray04630
JAK-STAT signaling pathway
ray04658
Th1 and Th2 cell differentiation
ray04659
Th17 cell differentiation
ray05140
Leishmaniasis
ray05145
Toxoplasmosis
ray05152
Tuberculosis
ray05160
Hepatitis C
ray05161
Hepatitis B
ray05162
Measles
ray05163
Human cytomegalovirus infection
ray05164
Influenza A
ray05165
Human papillomavirus infection
ray05166
Human T-cell leukemia virus 1 infection
ray05167
Kaposi sarcoma-associated herpesvirus infection
ray05168
Herpes simplex virus 1 infection
ray05169
Epstein-Barr virus infection
ray05171
Coronavirus disease - COVID-19
ray05200
Pathways in cancer
ray05203
Viral carcinogenesis
ray05212
Pancreatic cancer
ray05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
107517940 (JAK1)
04151 PI3K-Akt signaling pathway
107517940 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
107517940 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
107517940 (JAK1)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
107517940 (JAK1)
04658 Th1 and Th2 cell differentiation
107517940 (JAK1)
04659 Th17 cell differentiation
107517940 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
107517940 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107517940 (JAK1)
05203 Viral carcinogenesis
107517940 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
107517940 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
107517940 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
107517940 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
107517940 (JAK1)
05161 Hepatitis B
107517940 (JAK1)
05160 Hepatitis C
107517940 (JAK1)
05171 Coronavirus disease - COVID-19
107517940 (JAK1)
05164 Influenza A
107517940 (JAK1)
05162 Measles
107517940 (JAK1)
05168 Herpes simplex virus 1 infection
107517940 (JAK1)
05163 Human cytomegalovirus infection
107517940 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
107517940 (JAK1)
05169 Epstein-Barr virus infection
107517940 (JAK1)
05165 Human papillomavirus infection
107517940 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
107517940 (JAK1)
05140 Leishmaniasis
107517940 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107517940 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ray01001
]
107517940 (JAK1)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
107517940 (JAK1)
Protein kinases [BR:
ray01001
]
Non-receptor tyrosine kinases
JAK family [OT]
107517940 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
Jak1_Phl
FERM_F1
RIO1
SH2
Motif
Other DBs
NCBI-GeneID:
107517940
NCBI-ProteinID:
XP_016014614
LinkDB
All DBs
Position
Unknown
AA seq
1156 aa
AA seq
DB search
MQYLNIKEDCNAMAFCAKMRSSKKTEVNLEAPEPGVEVLFYLSDREPLRLGSGEYTAEEL
CIRAAQECCISPLCHNLFALYDENTKLWYAPNRTITVDDKTSLRLHYRMRFYFTNWHGTN
DNEQSVWRHSPKKQKNGYEKKKVPDATPLLDASSLEYLFAQGQYDLVKCLAPIRDPKTEQ
DGHDIENECLGMAVLAISHYAMIKKMQLPELPKDISYKRYIPETLNKSIRQRNLLTRMRI
NNVFKDFLKEFNNKTICDSSVSTHDLKVKYLATLETLTKHYGAEIFETSRLLISSENELN
WFHPNDSGNVLYYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKLENKQKKDEEKNKIR
EEWSNFSYFPEITHIVIKESMVSINKQDNKKMELKLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIQNGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKAEVLGGQKQFKNFQIEVQKGRYSLHGSDRSFPSLGDLMSHLKKQILRTDNISFVLK
RCCQPKPREISNLLVATKKAQEWQPVYPMSQLSFDRILKKDIMQGEHLGRGTRTHIYSGT
LVDYKEDEGISEEKRIKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEFVEGGPLDLFMHRKSDVLTTPWKLKVAKQLASALSYLEDKDLVHGNVCTKNLL
LAREGIDSECGPFIKLSDPGIPITVLTRQECIERIPWIAPECVEDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLIEKERFYESRCRPVTPSCKELADLMTRCMNYDPNQRPFFRAI
MRDINKLEEQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPS
GSLKEYLPKNKNKINLTQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLIQCKFYIASDVWSFGVTLHELLTYCDSD
SSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPHNCPDEIYHLMRKCWEFHPSNRTT
FQNLIEGFEALLKLGA
NT seq
3471 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatataaaagaggactgcaatgccatggctttctgtgctaaaatgcgg
agctccaagaagaccgaggtgaatctggaagcccctgagccaggggtggaagtgctcttc
tatctgtcggatagggagcccctccggctgggcagtggcgagtataccgcagaggagcta
tgcatccgggcggcacaagaatgctgtatctctcctctgtgtcacaacctttttgctctg
tatgatgagaacaccaagctctggtatgccccaaatcgcaccatcactgttgatgacaag
acatcgcttcggctccactatcggatgaggttctattttaccaactggcatgggaccaat
gataatgagcagtcagtatggcgacattctccgaagaagcagaaaaatggctatgagaaa
aaaaaagttccagatgcaactcctctccttgatgccagctccctggaatatctgtttgct
cagggacagtatgacttggtcaaatgcctggctccaattcgagaccccaagactgagcag
gatgggcacgacatagagaacgagtgtctggggatggccgtcctggccatctcccattat
gccatgataaagaagatgcagttgccagaactccccaaggacatcagctacaagcgatat
attccagaaacattgaataagtccatcagacagaggaaccttctcaccaggatgaggata
aataatgtcttcaaggatttcctcaaggaatttaacaacaagaccatttgtgacagcagc
gtgtccacacatgacctgaaggtgaaatacctggctaccttggaaactttgacaaaacat
tatggtgctgaaatatttgagacttccaggttactgatttcatcagaaaatgagctgaat
tggtttcatccaaatgacagtggaaatgttctctactatgaagtgatggtgactggaaat
cttggaatccaatggaggcagaaaccaaatgtcgttcctgtcgaaaaggaaaaaaataaa
ctgaaacggaaaaaactggaaaataaacagaagaaggatgaggagaaaaacaaaatccgg
gaagagtggagcaatttttcttacttccctgaaatcactcatattgtaataaaggaatct
atggtcagcattaataagcaggacaacaaaaaaatggaactgaagctctcttcccacgag
gaggccttgtcttttgtgtccctggtagatggctactttcggctcacagcagacgcccat
cattacctttgcaccgacgtggctcccccactgatcgtccacaacatacagaatggctgt
catggtccaatctgcacagaatatgccatcaataaattgcggcaagaaggaagcgaggag
gggatgtacgtgctgcggtggagctgcaccgacttcgacaacatcctcatgaccgtcacc
tgctttgaaaaggctgaggtgctgggtggccagaaacagttcaagaactttcagatcgag
gtgcagaagggtcgctacagtctgcacggttcggaccgcagcttccccagcctgggagac
ctcatgagccatctcaagaagcagatcctccgcacagacaacatcagcttcgtgttgaag
cgctgctgccagcccaagccccgagaaatctccaatctgctggtggcaactaagaaagcc
caggagtggcagcccgtctaccccatgagccagctgagtttcgatcggatcctcaagaaa
gacattatgcaaggtgaacaccttgggagaggcacgcggacacacatctactctgggacc
ctggtggattacaaggaggacgaaggaatatctgaagagaagagaataaaagtgatcctc
aaagtcttggaccccagccacagggacatttctctggcattcttcgaggcagccagcatg
atgaggcaggtctcccacaaacacatcgtatacctctatggcgtctgtgtccgagacgtg
gagaatatcatggtggaagagtttgtggagggagggcccctggatctcttcatgcaccgg
aaaagtgatgtcctcaccacaccatggaagctcaaagtcgctaaacagctggccagcgcc
ttgagttacttggaggataaagacctggtccacggaaacgtgtgcacgaaaaacctcctc
ctggctcgtgagggcattgacagtgagtgcggcccattcatcaagctcagtgaccccggc
atccccatcacggtgctgaccaggcaagagtgcatagaacgcatcccgtggattgctcct
gagtgtgtcgaagactccaagaacctgagcgtggccgctgacaagtggagcttcggaacc
acactctgggaaatctgctacaacggtgagatccccctgaaagacaagacgctgatcgag
aaagaaagattctatgaaagccggtgcaggccagtgacgccatcttgtaaggagctggca
gaccttatgactcgctgcatgaactatgaccctaaccagagaccctttttccgagccatc
atgagagacatcaataagctggaagagcagaatccagacattgtttcagaaaaaaagcca
gcaactgaagtggaccccacacattttgaaaagcggttcttgaagaggatccgtgacttg
ggagagggccactttgggaaagttgagctctgcaggtatgaccctgaaggggacaataca
ggagagcaggtggctgtcaaatccctgaagcctgagagtggaggtaaccacatagctgat
ctgaagaaggaaattgaaatcttaaggaacctctatcatgagaacattgtgaagtacaaa
ggcatctgcacagaagatggaggaaatggtattaagctcatcatggaatttctgccttca
ggaagcttgaaggaatatcttccaaagaataagaacaaaattaacctcacccagcagtta
aaatatgccgttcagatttgtaaggggatggactatttgggttcacgacaatacgttcac
cgagacttagcagcaagaaatgtcctcgttgagagtgaacaccaagtgaaaattggagac
tttgggttaaccaaagcaatcgaaaccgataaggagtactacacagtcaaggatgatcgg
gacagccctgtgttttggtacgctccagaatgtttaattcagtgtaaattttatatcgcc
tctgacgtctggtctttcggagtgactctgcacgagctgcttacttactgtgattcagat
tccagtcccatggcattgttcctgaaaatgataggccctactcatggccagatgacagta
acaagacttgtgaatacattaaaagaaggaaaacgtttgccttgtccacataactgtcca
gatgagatttatcaccttatgagaaaatgctgggaattccacccatctaatcggacaacc
tttcagaaccttatcgaaggatttgaagcacttttaaaattaggagcatga
DBGET
integrated database retrieval system
