Rousettus aegyptiacus (Egyptian rousette): 107520393
Help
Entry
107520393 CDS
T06036
Gene name
PLCE1
Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray00562
Inositol phosphate metabolism
ray01100
Metabolic pathways
ray04014
Ras signaling pathway
ray04015
Rap1 signaling pathway
ray04020
Calcium signaling pathway
ray04024
cAMP signaling pathway
ray04070
Phosphatidylinositol signaling system
ray04919
Thyroid hormone signaling pathway
ray04933
AGE-RAGE signaling pathway in diabetic complications
ray05205
Proteoglycans in cancer
Module
ray_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
107520393 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
107520393 (PLCE1)
04015 Rap1 signaling pathway
107520393 (PLCE1)
04020 Calcium signaling pathway
107520393 (PLCE1)
04070 Phosphatidylinositol signaling system
107520393 (PLCE1)
04024 cAMP signaling pathway
107520393 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
107520393 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
107520393 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
107520393 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ray04131
]
107520393 (PLCE1)
Enzymes [BR:
ray01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
107520393 (PLCE1)
Membrane trafficking [BR:
ray04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
107520393 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
107520393 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
107520393
NCBI-ProteinID:
XP_016019634
LinkDB
All DBs
Position
Unknown
AA seq
2302 aa
AA seq
DB search
MTSEEMAASVLIPVTQKKVVSSQSAVDESSDKVLDVSVSKAHTVRQSGSIPSYTISKPNK
LKEESSGSNLPKILSIAREKIMSDENSNEKCWEKNTPDSVEDPNINCNNISENHQHGLPQ
SQFYETCDSLTEEGLCLETGIPSSLERKVFPGIQLEMNRPPMGIRALGNQSATIEPGKAQ
PDGNMAVFHFHYELDRRMSDTFCTLSDNLILGDCGNCVSLPGVGEEQKKNYNAYTCKLME
LAENCDNENGQLQCDHCDTLNDKYLCCEGSCQKASVVCSSDSFCRKDFTDSPSAKDFLSH
FEDFPDNCEDVEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLAA
WSYIDQKRSGLSLPCGAATGWQSTVVTRQDGSQCLSEAQWYPIYNAVRRGEETEDTIGSL
LHFFTKLPDSETAHERINVGPCLKQCVLNNVCEFRATLQRTSVSQYITGSLLEATTSLGA
RSGLLNTFGGSTGRMMLKERQPATSVANSNALPSSSAGISKELIDLQPLIQFPEEVASIL
MEQEQNIYRRVLPVDYLCFLTRNLGTPECQASLPGLKASISASVLTSQNGEHNALEDLVM
RFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNTVMEFLAGLRSRKVLKM
WQFMDQCDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDG
TSGLLKLCPRYNSQEEALEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSR
SLETEEEDSPNEGNSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDPHGLEEPQKAF
DHGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTA
SPASAKAKLGMLSNTSEPGKFPLLGNAGLSGLVEGVLDLFSAKAVYMGHPSIDIHTVCVQ
NKLSSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQR
QQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGISAKSTEKPSMQRNNTL
GISTTKKKKKILMRGESGEATDDEMATRKAKMHRECRSRSGSDPQDANEQEESEANAIPS
PPNPLPSRRAHSLTTAVSPNLASGTSSPIRPVSSPALSSNKSPSSAWSSSSWHGRIKGGM
KGFQSFMVSDSSMSFVEFVELFKSFSVRSRKDLKDLFDLYAVPCNRAGSESAPLYTNLTI
DENTSGLQPDLDLLTRNVSNLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
IFGVGILQLNDFLVNCQGEHCTYDETLSIIQKFEPSISMCHQGLMSFEGFARFLMDKDNF
ASKNDESQENVRELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEI
FKTVFGEKLVTKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANLPPATNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYN
EEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGL
STLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSACEGMRQAWEESSSPLS
PTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPN
PLMFWLHGIQLVALNYQTEDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLE
RDLDDMEPAIYSLTIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMW
NEQFLFRVHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISS
LFINSRRMEENSSSSTMPASLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSISGGTKAKQ
LLQQILTTEQDIKLIATDYFLMEEKYFISKEKNECRKQPFQRVIGPEEEILQILSSWFPE
EGYVGRIVLRPQQENLEEKSIVQDDKEVILSTEEESFFVQVHDVSPEQPRTVIKAPRIST
AQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTSNKRSSTPKSSQRVLLDQECVFQ
AQSKWKGAGKFILKLKEQVQASREDKRKGISFASELKKLTKSTKQPRGLTSPSQVLASES
VQNKEEKPVGGLFSSDTLDYRQ
NT seq
6909 nt
NT seq
+upstream
nt +downstream
nt
atgacatctgaagaaatggcagcttctgttctcatacctgtgactcagaaaaaagtggtg
tcttctcagtcggctgtagatgaaagtagtgacaaggtcctggatgtcagtgtttcaaag
gcacatactgttaggcagagtgggtctataccatcttataccatctcaaaaccaaacaaa
cttaaagaagaatcttctggaagcaacttgcccaagattctctcaattgcaagggagaaa
ataatgagtgatgaaaacagtaatgaaaagtgctgggagaaaaacacaccagattctgtg
gaagaccctaacattaactgcaataacatatcggaaaaccatcagcatggccttcctcag
agccagttttatgaaacgtgtgattctctcacagaggaaggcctctgtttggaaactgga
atcccttcttcactggaaagaaaggtgttccctggaattcagctggaaatgaatagacct
cccatgggcattagagccttaggcaatcagtcagcaaccatagagcctggcaaggcacaa
cctgatggcaacatggcggtatttcattttcattatgaacttgacagaagaatgtcagac
actttctgtaccctatcggataacttgattttgggtgattgtggaaactgtgtatcactg
cctggtgttggtgaggagcaaaagaaaaattataatgcatatacttgtaagctgatggaa
ttggcagaaaactgtgataatgagaatggccagctgcaatgtgatcattgtgacaccttg
aatgacaaatacttgtgctgcgaaggttcctgccaaaaggccagtgtggtatgttcaagt
gacagcttttgcagaaaggattttactgatagtccatctgctaaggactttctgagccat
tttgaagacttccctgataactgtgaagatgtagaggacttttttaaaagtaaaaaggag
cggtccactttgttagtgaggagattttgtaaaaatgacagggaagttaagaaatctgtg
tatacagggacaagggcaattatgaggactctgccttctggtcacattgggctggcagct
tggagttacattgatcagaaaagaagtggtctctcattgccttgtggggcagcaacggga
tggcagtcaacagtggtgactaggcaagatgggagccaatgtctgtcagaagcccagtgg
tatccgatctacaatgcagtgagaagaggagaagaaacagaagatacaattggatctctt
ctccatttcttcacaaagctcccagactccgagacagcccatgaaaggattaacgttggt
ccctgcttaaagcaatgtgtcctaaacaacgtttgtgaatttcgtgccaccctccaaagg
acttctgtatctcagtacatcaccggttctctcctagaggcaaccacatctttaggagca
aggagtggccttctcaatacttttggaggatctaccggacgaatgatgctgaaagaacgc
caaccagccacctccgtggccaattccaatgccctcccttcaagttcagctgggatcagc
aaggaactgattgatctgcagcccctcatccagttcccagaggaagtcgctagcatcctg
atggagcaggaacagaatatttaccgaagggtcttgccagttgactacctttgcttcctg
actcggaacttgggcactccagaatgccaggcttcactgcccggcctcaaagcgtccatc
tcagcatcagttctcacctcccagaatggagagcacaacgccctcgaagatcttgtgatg
agatttaatgaggtgagctcctgggtaacgtggctgatcctcacggcgggttccatggag
gagaagcgggaagtcttctcgtatttggtgcatgtggccaaatgctgctggaacatggga
aactacaacaccgtcatggagttcttggccggcctcaggtcaagaaaagttttgaagatg
tggcagtttatggaccagtgcgacctggagaccatgcggagcctgaaggatgccatggct
cagcacgagtcatcctgtgagtacaggaaggtggtgacgcgggctctgcacatccccggc
tgcaaggtggttccattctgcggagtgttcctgaaggagctctgtgaagttcttgacgga
acctctggccttctgaagctttgcccgaggtacaattcccaagaagaagctctagagttc
gtagccgactacagtggacaagataatttcttacaacgagtgggacaaaatggcttaaag
aattcagaaaaggagtccacagtcaacagcatctttcagatcatcaggagctgcagtcga
agtctggagacggaggaggaggacagccccaatgaagggaacagctctaggaaaaactcc
ttgaaggataaagctcgatggcaatttataattggagatttgttggattctgaaaatgac
atttttgagcagccgaaagaatgggatcctcacggattagaagaaccgcagaaggccttt
gaccatgggacagagctcatcccgtggtacgtcctatccatccgagctgatgtgcaccag
ttcctactgcagggagccacggttatccactatgaccaggacacacacctctctgcccgc
tgcttcctccagcttcagcctgacaatagcaccttgacctggataaagcccaccactgcc
tccccagccagtgctaaagcaaaacttggtatgcttagtaacacatctgagcctggcaaa
ttcccattactgggcaatgctggattaagtggcctggtagagggggtcttggatctgttt
tcagcaaaggctgtgtacatgggacaccctagcattgatatacacactgtgtgtgttcag
aacaaactgagtagcatgtttctctcagagactggtgtgacattgctctatgggcttcag
accacggacaatagattattgcattttgtggcaccaaagcacacagctaaaatgctcttc
agcggattattggaactcactagggctgtgagaaagatgaggaagttccctgaccaaagg
cagcagtggctacggaaacaatacgtcagcctctatcaggaggatggacggtacgaaggc
ccgactttggctcatgctgtggagttgtttggtggcagacgatggagtactcgaaacccc
agccctgggatatcagcaaagagtactgagaagcccagcatgcagaggaacaacaccttg
ggcataagcaccaccaagaaaaagaagaaaatccttatgaggggtgagagtggagaggca
accgacgacgagatggccacccgaaaggccaaaatgcacagagagtgtcggagccggagt
ggctctgatcctcaagacgctaacgaacaagaagaatcagaggcaaatgccatcccaagc
ccgcctaaccctctcccttccagaagagcccactccctgaccacggctgtgtcacctaac
ttggcttccgggacatcatctcccatcaggccagtgtcctcccccgcgctgtcttcaaac
aagagcccatccagtgcttggagcagcagcagctggcatgggcggatcaaaggaggaatg
aaaggctttcagagtttcatggtttcagacagtagcatgagttttgttgaatttgttgag
ctgttcaaatcattcagtgtaaggagcagaaaggacctgaaggatctctttgacctctat
gccgtgccctgcaaccgagcaggctctgagtcagccccactctacaccaacctaaccatt
gatgaaaacaccagcggtcttcagcctgacctagatttgttgaccagaaatgtctcgaat
ttggggttgttcattaaaagtaaacagcaactgtcagacaaccagaggcagatctctgat
gccattgctgctgcaagtatcgtgacaaatggtactggggtcgagagcacatccctgggc
atatttggggttggaatactccagctcaatgactttctagtgaattgccaaggagaacac
tgcacttacgatgaaaccctcagcatcatccagaagtttgagcctagcattagtatgtgt
catcaaggcctaatgtcatttgaaggatttgcaaggtttctgatggataaagataatttt
gcctcaaaaaatgatgaatcgcaggagaacgttagagaattgcagctgcccctctcctac
tattacatcgaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcc
tcagtagagctctacagccaggttctcttgcaaggctgcaggagcgtagagttggactgc
tgggatggagatgatgggatgcccatcatttaccatggacacacactgacaaccaagatc
cccttcaaggaagtggttgaagccattgatcgcagtgccttcatcaactctgacctgcca
atcatcatatcgattgagaaccactgttcattgcctcagcaacgaaaaatggccgaaatt
tttaagactgtgtttggagaaaaactggtgactaaattcttatttgagagtgacttctca
gatgatccaatgcttccctcgcctgaccaacttagaaggaaagtgcttcttaaaaataag
aagctaaaggcccatcagacaccagtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttataatggtgggaatgccaacctcccacctgctactaacgag
gaggaggaagatgaagaagacgaatatgattatgactacgaatccctctctgacgacaac
attctagaagacagacctgaaaataaatcatgtaatgacaagcttcaatttgagtataat
gaagaaatccccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtt
tatgacatggaactgggagaagaattttatcttcctcagaataaaaaggaaagcagacag
attgcaccagagctttctgaccttgtcatctattgccaagcagtaaaatttccaggcctg
tcaactctaaatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatt
tttggcaacaatccgggcagaatgagccctggggagacagcatcattcaacaaagcatct
ggaaaaagtgcctgcgaaggaatgcgacaggcctgggaggaatcttcttccccactcagc
ccaaccacatccctcagcgctatcattagaactcccaaatgctatcatatctcatcgctg
aatgaaaatgccgccaaacgtctgtgtcgcaggtattctcagaaactgatccagcacacc
gcctgtcagctgctgagaacctacccagctgccacccgtatcgactcgtccaaccctaac
cccctcatgttctggctgcatgggatacagctcgtggcactcaactaccaaacagaggat
ctccctttacatttaaatgctgccatgttcgaggccaatggtggctgtggttatgtttta
aaacctccagtcctgtgggacaagaactgtcctatgtatcagaagttttctcccttggaa
agagacctggacgacatggagcctgccatctattctttaactattgtctctggacaaaac
gtgtgcccgagtaacagcacaggaagcccgtgtattgaagtcgatgtcctgggaatgccc
ctggacagttgccattttcgcacgaagcccatccatcgcaataccctgaaccccatgtgg
aatgaacagtttctcttccgagttcattttgaagatctcatatttcttcgttttgccgtt
gtggaaaacaacagctcagcagtaactgctcagagaatcattccactcaaggctttaaag
cgaggatatcgacatcttcagctgcgaaacctgcacaatgaagtcttggaaatctccagt
ttattcataaacagcagaaggatggaagaaaattcctctagcagtactatgccagcctct
ttgatgtttaatacagaagaaagaaaatgtttgcagactcacagagtcacggttcatggg
gtcccaggtccagagccctttactgttttctctataagtggaggcaccaaggcaaagcag
cttctccaacaaattctgaccaccgaacaagacatcaaacttattgccacagattatttt
ttgatggaagaaaaatattttatatctaaagaaaagaatgaatgcagaaaacaaccattc
cagagagtcattggtccagaagaagagatcttacagattttaagcagctggtttccagaa
gagggatacgttggcagaattgtcttaagaccccagcaggaaaacctagaagagaaaagc
atcgtgcaagatgacaaggaggtgatcttgagcacggaggaggagagtttctttgtccaa
gtgcatgatgtttctcccgagcaaccgcggacagtcatcaaagcaccccgcatcagcacc
gcacaggatgtcattcagcagaccttatgcaaagccaaatactcctatagcatcctgagc
aaccccaacccaagtgactatgtgcttttggaagaggtggtgaaagacacctccaacaag
aggtcttctaccccaaagtcctcccagcgggtcctcttggatcaggagtgtgtgtttcaa
gcacaaagcaagtggaaaggtgcaggaaaattcatcctgaagctaaaggagcaggtgcag
gcatcccgagaagacaaaagaaaaggcatttcttttgcaagtgaactcaagaagctcacc
aagtcaactaaacagccccgaggactcacatcaccttctcaggtcttggcctcagaaagt
gtccaaaacaaggaggaaaaacctgtgggaggcttgttctccagcgacacgctagactac
cgacagtga
DBGET
integrated database retrieval system
