Rousettus aegyptiacus (Egyptian rousette): 107520699
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Entry
107520699 CDS
T06036
Gene name
ERBB2
Definition
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray01521
EGFR tyrosine kinase inhibitor resistance
ray01522
Endocrine resistance
ray01524
Platinum drug resistance
ray04010
MAPK signaling pathway
ray04012
ErbB signaling pathway
ray04020
Calcium signaling pathway
ray04066
HIF-1 signaling pathway
ray04151
PI3K-Akt signaling pathway
ray04510
Focal adhesion
ray04520
Adherens junction
ray04530
Tight junction
ray05200
Pathways in cancer
ray05205
Proteoglycans in cancer
ray05206
MicroRNAs in cancer
ray05212
Pancreatic cancer
ray05213
Endometrial cancer
ray05215
Prostate cancer
ray05219
Bladder cancer
ray05223
Non-small cell lung cancer
ray05224
Breast cancer
ray05226
Gastric cancer
ray05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107520699 (ERBB2)
04012 ErbB signaling pathway
107520699 (ERBB2)
04066 HIF-1 signaling pathway
107520699 (ERBB2)
04020 Calcium signaling pathway
107520699 (ERBB2)
04151 PI3K-Akt signaling pathway
107520699 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
107520699 (ERBB2)
04520 Adherens junction
107520699 (ERBB2)
04530 Tight junction
107520699 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107520699 (ERBB2)
05206 MicroRNAs in cancer
107520699 (ERBB2)
05205 Proteoglycans in cancer
107520699 (ERBB2)
05230 Central carbon metabolism in cancer
107520699 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
107520699 (ERBB2)
05226 Gastric cancer
107520699 (ERBB2)
05219 Bladder cancer
107520699 (ERBB2)
05215 Prostate cancer
107520699 (ERBB2)
05213 Endometrial cancer
107520699 (ERBB2)
05224 Breast cancer
107520699 (ERBB2)
05223 Non-small cell lung cancer
107520699 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107520699 (ERBB2)
01524 Platinum drug resistance
107520699 (ERBB2)
01522 Endocrine resistance
107520699 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ray01001
]
107520699 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ray04147
]
107520699 (ERBB2)
04090 CD molecules [BR:
ray04090
]
107520699 (ERBB2)
Enzymes [BR:
ray01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
107520699 (ERBB2)
Protein kinases [BR:
ray01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
107520699 (ERBB2)
Exosome [BR:
ray04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
107520699 (ERBB2)
CD molecules [BR:
ray04090
]
Proteins
107520699 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
APH
Kinase-like
Motif
Other DBs
NCBI-GeneID:
107520699
NCBI-ProteinID:
XP_016020258
LinkDB
All DBs
Position
Unknown
AA seq
1254 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGATGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDSYALAVLDNG
DPLDSATPAVGAAPGGLQELQLRSLTEILKGGVLIQRNPQLCHQDTILWKDIFHKNNQLA
LMLIDNNRSRACQPCSPACKASHCWGESSKDCQRLTRTVCASGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREARAVTSAN
VLEFAGCKKIFGSLAFLPESFAGDPASSTAPLQPEQLRVFETLEEITGYLYISAWPETLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNAHLCFVHTV
PWDQLFRNPHQALLHSANRPEDECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDKYCLPCHPECQPQNGSVTCVGSGADQCVACAHYKDSPFCVARC
PSGVKPDLSFMPIWKFPDEKGTCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
TLLVMIIGVVFGILIRRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEEVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPVPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDSDLGVGAAKGLQTLSPHDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEARPQPPSPLDGPPTPRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPRG
KAASQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3765 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctccttctcgccctcctgccccccggagcc
acgggcactcaagtgtgcactggcacagatatgaagctgcggctcccagccagtcctgag
acccacctggacatgctccgccacctctaccagggctgtcaggtggtgcaggggaacctg
gaactcacctatctgcctgccaatgccagcctctctttcctacaggacatccaggaggtg
cagggttatgtgctcatcgctcacaaccaagtgagacaggtcccactgcagaggctgcga
atcgtgcgaggcacccagctatttgaggacagctatgccctggccgtgctggacaatgga
gaccctctggacagtgccacccctgctgttggggctgccccaggaggactgcaggagctg
cagctgcgaagcctcacagagatcctgaagggaggggtcttgatccagcggaaccctcag
ctctgccaccaggatacgattttgtggaaggacatcttccacaagaacaaccagctggcc
ctcatgctgatagacaacaaccgctcccgggcctgccaaccctgttctccagcttgtaaa
gcctctcactgctggggagaaagttccaaggattgtcagcgcttgacgcgaactgtctgt
gccagtggctgtgcccgatgcaagggcccgctgcctaccgactgctgccatgagcagtgt
gctgccggctgcacgggccccaagcactctgactgcctggcctgcctccacttcaaccac
agtggcatctgtgagctgcactgcccagccctggtcacctacaacacggacaccttcgag
tccatgcccaaccctgagggccggtatacctttggtgccagctgtgtgaccgcctgtccc
tacaactacctatcgacggacgtgggatcctgcaccctagtctgtccccttaacaaccaa
gaagtgacagctgaagatggaacacagcggtgtgagaaatgcagcaagccttgtgcccga
gtgtgctatggcctgggcatggaacacctgcgggaggcaagggcggtcactagtgccaat
gtcctggagtttgctggctgcaagaagatctttgggagcctggcgtttctgccggagagc
tttgcgggggacccagcctccagcactgcccccctacagcctgagcagctcagagtgttt
gagaccttagaggaaattacaggttacctgtacatctcagcgtggccagaaaccctgcct
gacctcagtgtcttccagaacctgcgagtaatccggggacgagttctgcatgatggtgcc
tactcgctgaccctgcaaggcctgggcatcagctggctggggctgcgctcactgcgggaa
ctgggtagtgggctggccctcatccaccgcaacgcccacctctgctttgtgcacacggtg
ccctgggaccagctctttcggaaccctcaccaggccctgctccacagtgctaaccgacca
gaggacgaatgtgtgggtgaaggcctggcctgctacccgctgtgtgcccatgggcactgc
tggggtccgggacccacccagtgtgtcaactgcagccagttccttcggggccaggagtgc
gtggaggagtgccgagtactgcaggggctcccccgggagtatgtgaaggacaagtactgt
ctgccgtgccaccccgagtgtcaaccccagaatggctcagtgacctgcgtaggatcgggg
gctgaccagtgtgtggcctgtgcccactacaaggactctcccttctgcgtggctcgctgc
cccagtggtgtgaaacctgacctctccttcatgcccatctggaagttcccagatgagaag
ggcacgtgccagccgtgccccatcaactgcacccactcctgtgtggacctggatgacaag
ggctgccctgctgagcagagagccagccctgtgacgtccatcattgctgctgtggtggga
actctgctggtcatgattataggggtagttttcggcatcctaatcaggcgaaggaggcag
aagatccggaagtacacgatgagaaggctgctgcaggaaacagagctggtggagccgttg
acacctagtggagcaatgcctaaccaggctcagatgcggatcctaaaagagacagagctg
aggaaggtgaaggtgcttggatcaggagcttttggcacagtctacaagggcatctggatc
cctgatggggagaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatct
cccaaagccaacaaagaaatcctggacgaagcatatgtgatggctggtgttggctcccca
tatgtgtcgcgcctcctgggcatctgcctgacctctaccgtgcagctggtgacacagctt
atgccctatggctgcctcctagaccatgtccgggaacaccgtggacgcctgggctcccag
gacctgctgaactggtgtgtgcagattgcaaaggggatgagctacttggaggaagtgcgg
cttgtgcacagggacctggctgcccggaatgtgctggtcaagagtcccaaccatgtcaag
atcacagactttgggctggctcggctgctggacattgacgagacagagtaccatgcggat
gggggcaaggtacccatcaagtggatggcgttggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagctacggtgtgactgtatgggagctgatgacttttggggcc
aaaccttacgatgggatcccagcccgggagatccctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccatcgatgtctacatgatcatggtcaaatgttggatg
attgactccgagtgtcggcctcggttccgggagttggtggccgaattctcccgcatggcc
agggatccccagcgctttgtggtcatccagaatgaggatctgggccctgccagccccttg
gacagcaccttctaccgctcgctgctggaggatgacgacatgggggacctggtggatgcg
gaggagtacctggtaccccagcagggcttcttctgcccagatcctgttccgggtgctggg
ggcacagcccaccgcaggcaccgcagctcatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctccgaagaggagccccccaagtctccactggcaccttcagaaggg
gcaggctctgatgtgtttgacagtgatttgggagtgggggcagccaagggactgcaaact
ctctccccacatgaccccagccctctacagcggtacagtgaggaccccacagttcccttg
cctcctgaaactgatggctacgttgctcccctgacctgcagcccccagcccgaatacgtg
aaccagccagaggctcgcccgcagcctccctcacccctagatggccccccgactcctcga
cctgctggtgccacgctggaaaggcccaagacactctctcctgggaagaacggggttgtc
aaagatgtttttgcctttgggggtgctgtggagaaccccgagtacttggcaccccgtggc
aaggctgcttcacagccccaccctcctccagccttcagtccagcttttgataacctctat
tactgggaccaggacccatcagagcggggttctccacctagcacctttgaagggacccct
acggcagagaaccctgagtacctgggcctggatgtgccagtgtga
DBGET
integrated database retrieval system
