KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108512466
Entry
108512466         CDS       T04641                                 

Gene name
TGFBR1
Definition
(RefSeq) transforming growth factor beta receptor 1
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04010  MAPK signaling pathway
rbb04060  Cytokine-cytokine receptor interaction
rbb04068  FoxO signaling pathway
rbb04144  Endocytosis
rbb04218  Cellular senescence
rbb04350  TGF-beta signaling pathway
rbb04371  Apelin signaling pathway
rbb04380  Osteoclast differentiation
rbb04390  Hippo signaling pathway
rbb04520  Adherens junction
rbb04659  Th17 cell differentiation
rbb04926  Relaxin signaling pathway
rbb04933  AGE-RAGE signaling pathway in diabetic complications
rbb05142  Chagas disease
rbb05161  Hepatitis B
rbb05166  Human T-cell leukemia virus 1 infection
rbb05200  Pathways in cancer
rbb05210  Colorectal cancer
rbb05212  Pancreatic cancer
rbb05220  Chronic myeloid leukemia
rbb05225  Hepatocellular carcinoma
rbb05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108512466 (TGFBR1)
   04350 TGF-beta signaling pathway
    108512466 (TGFBR1)
   04390 Hippo signaling pathway
    108512466 (TGFBR1)
   04371 Apelin signaling pathway
    108512466 (TGFBR1)
   04068 FoxO signaling pathway
    108512466 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    108512466 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    108512466 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    108512466 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    108512466 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    108512466 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    108512466 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    108512466 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108512466 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    108512466 (TGFBR1)
   05212 Pancreatic cancer
    108512466 (TGFBR1)
   05225 Hepatocellular carcinoma
    108512466 (TGFBR1)
   05226 Gastric cancer
    108512466 (TGFBR1)
   05220 Chronic myeloid leukemia
    108512466 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    108512466 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108512466 (TGFBR1)
   05161 Hepatitis B
    108512466 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    108512466 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108512466 (TGFBR1)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     108512466 (TGFBR1)
Protein kinases [BR:rbb01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   108512466 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH FTA2
Other DBs
NCBI-GeneID: 108512466
NCBI-ProteinID: XP_017703226
LinkDB
Position
Un
AA seq 506 aa
MVLDGRLTGMTNTGIWPQGVYSFIGERKSNSALQCFCHLCTKDNFTCVTDGLCFVSVTET
TDKVIHNSMCIAEIDLIPPDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTTGPFSVKS
SPGLGPVELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTL
KDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSR
EERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTV
TVEGMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVR
HDSATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSI
GGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYA
NGAARLTALRIKKTLSQLSQQEGIKM
NT seq 1521 nt   +upstreamnt  +downstreamnt
atggtgttagatggcagattgacaggaatgactaatacaggtatctggcctcaaggagtt
tacagtttcataggagaaagaaaaagcaattctgcattacagtgtttctgccacctctgt
acaaaagacaattttacttgtgtgacagatgggctctgctttgtctctgtcacagagacc
acagacaaagttatacacaacagcatgtgtatagctgaaattgacttaattcctccagat
aggccatttgtttgtgcaccctcttcaaaaactgggtctgtgactacaacatattgctgc
aatcaggaccattgcaataaaatagaacttccaactactggccctttttcagtaaagtcg
tcacctggccttggtcccgtggaactggcagctgtcattgctggaccagtgtgctttgtc
tgcatctcactcatgttgatggtatatatctgccacaatcgcactgtcattcaccatcga
gtgccaaatgaagaggacccttcattagatcgcccttttatttcagagggtaccacgttg
aaagacttaatttatgatatgacaacatcaggttctggctcaggtttaccattgcttgtt
cagaggacaattgcgagaactattgtgttacaagaaagcattggcaaaggtcgatttgga
gaagtgtggcgaggaaagtggcggggagaagaagttgctgttaagatattctcttctaga
gaagaacgttcatggttccgtgaggcagagatttatcaaactgtaatgttacgtcatgaa
aacatcctgggatttatagcagcagacaataaagacaatggcacttggactcagctctgg
ttggtgtcagattatcatgagcatggatccctttttgattacttaaacagatacacagtt
actgtggaaggaatgataaaacttgctctgtccacagcgagtggtcttgcccatcttcac
atggagattgttggtacccaaggaaagccagccattgctcatagagatttgaaatcaaag
aatatcttggtaaagaagaatggaacttgctgtattgcagacttaggactggcagtaaga
cacgattcagccacagataccattgatattgctccaaaccacagagtgggaacaaaaagg
tacatggcccctgaagttctcgatgattccataaatatgaaacattttgaatccttcaaa
cgtgctgacatctatgcaatgggcttagtattctgggaaattgctcgacgatgttccatt
ggtggaattcatgaagattaccagctgccttattatgatcttgtaccttctgacccatca
gtggaagaaatgagaaaagttgtttgtgaacagaagttaaggccaaatatcccaaacaga
tggcagagctgcgaagccttgagagtaatggctaaaattatgagagaatgttggtatgcc
aacggagcagctaggcttacagcattgcggattaagaaaacattatcacaactcagtcaa
caggaaggcatcaaaatgtaa

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