KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108518318
Entry
108518318         CDS       T04641                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb01521  EGFR tyrosine kinase inhibitor resistance
rbb04062  Chemokine signaling pathway
rbb04066  HIF-1 signaling pathway
rbb04068  FoxO signaling pathway
rbb04217  Necroptosis
rbb04550  Signaling pathways regulating pluripotency of stem cells
rbb04630  JAK-STAT signaling pathway
rbb04659  Th17 cell differentiation
rbb04917  Prolactin signaling pathway
rbb04920  Adipocytokine signaling pathway
rbb04931  Insulin resistance
rbb04933  AGE-RAGE signaling pathway in diabetic complications
rbb04935  Growth hormone synthesis, secretion and action
rbb05145  Toxoplasmosis
rbb05160  Hepatitis C
rbb05161  Hepatitis B
rbb05162  Measles
rbb05163  Human cytomegalovirus infection
rbb05167  Kaposi sarcoma-associated herpesvirus infection
rbb05169  Epstein-Barr virus infection
rbb05200  Pathways in cancer
rbb05203  Viral carcinogenesis
rbb05205  Proteoglycans in cancer
rbb05206  MicroRNAs in cancer
rbb05212  Pancreatic cancer
rbb05221  Acute myeloid leukemia
rbb05223  Non-small cell lung cancer
rbb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    108518318 (STAT3)
   04066 HIF-1 signaling pathway
    108518318 (STAT3)
   04068 FoxO signaling pathway
    108518318 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    108518318 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    108518318 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    108518318 (STAT3)
   04062 Chemokine signaling pathway
    108518318 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    108518318 (STAT3)
   04917 Prolactin signaling pathway
    108518318 (STAT3)
   04935 Growth hormone synthesis, secretion and action
    108518318 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108518318 (STAT3)
   05206 MicroRNAs in cancer
    108518318 (STAT3)
   05205 Proteoglycans in cancer
    108518318 (STAT3)
   05203 Viral carcinogenesis
    108518318 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108518318 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    108518318 (STAT3)
   05221 Acute myeloid leukemia
    108518318 (STAT3)
   05223 Non-small cell lung cancer
    108518318 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease
    108518318 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    108518318 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108518318 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    108518318 (STAT3)
   05161 Hepatitis B
    108518318 (STAT3)
   05160 Hepatitis C
    108518318 (STAT3)
   05163 Human cytomegalovirus infection
    108518318 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    108518318 (STAT3)
   05169 Epstein-Barr virus infection
    108518318 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108518318 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    108518318 (STAT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:rbb03000]
    108518318 (STAT3)
Transcription factors [BR:rbb03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    108518318 (STAT3)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int SH2 MerR-DNA-bind Syntaxin-6_N E2R135 DUF4795 Fib_alpha
Other DBs
NCBI-GeneID: 108518318
NCBI-ProteinID: XP_017712065
LinkDB
Position
Un
AA seq 837 aa
MTACLGQAGAGRGLAEGAVIQRFPELRWRRPGGGAGGSDVAAEGTSPNRILDRHPGSALS
LPLGSEKPFGLREPRRPPPAHAQPRPLGLCWRNSRMAQWNQLQQLDTRYLEQLHQLYSDS
FPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRR
IKQFLQVFWQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDF
NYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKT
LTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYK
GDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVK
FPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLR
EQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLEVNHSLPVVVISNICQMPNA
WASXLWYNMLTNNPKNVNXFTKPPIGTWDQVGRGPDWQFSSTTKRGRASSSXLTLARENF
LGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKE
RERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAE
IIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGAAPYLKTKFICV
TPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM
NT seq 2514 nt   +upstreamnt  +downstreamnt
atgacggcgtgcctcggccaggctggggctgggcggggattggctgaaggggctgtaatt
cagcggtttccggagctgcggtggcgtagacccggagggggagccgggggttccgacgtc
gcagccgagggaacaagccccaaccggatcctggacaggcaccccggctcggcgctgtct
ctccccctcggctcggagaagcccttcggcctgagggagccccgccgcccgcccccggcg
cacgcgcagccccggcctctcggcctctgctggagaaacagcaggatggcccaatggaat
cagctacagcagcttgacacacggtacctggagcagctccatcagctctacagtgacagc
ttcccaatggagctgcggcagtttctggccccttggattgagagtcaagattgggcatat
gcggccagcaaagaatcacatgccactttggtgtttcataatctccttggcgagattgac
cagcagtatagccgcttcctgcaagagtcgaatgttctctatcagcacaatctacgaaga
atcaagcagtttcttcaggtattttggcagcaagggggccaggccaaccaccccacagca
gctgtggtgacggagaagcagcagatgctggagcagcaccttcaggatgtccggaagaga
gtgcaggatctagaacagaaaatgaaagtggtagagaatctccaggatgactttgatttc
aactataaaaccctcaagagtcaaggagacatgcaagatctgaatggaaacaaccagtca
gtgaccaggcagaagatgcagcagctggaacagatgctcactgcgctggaccagatgcgg
agaagcatcgtgagtgagctggcggggcttttgtcagcgatggagtacgtgcagaaaact
ctcacagacgaggagctggctgactggaagaggcggcaacagattgcctgcattggaggt
ccgcccaacatctgcctagatcggctagaaaactggataacgtcattagcagaatctcaa
cttcagacccgtcaacaaattaagaaactggaggagttgcagcaaaaagtttcctacaaa
ggggaccccattgtacagcaccggccgatgctggaggagagaattgtggagctattcaga
aacttaatgaaaagtgcctttgtggtggagcggcagccttgcatgcccatgcatcccgac
cggcccctcgtcatcaagactggcgtccagttcactaccaaagtcaggttgctggtcaaa
ttccctgagttaaattatcagcttaaaattaaagtgtgcattgacaaagactctggggat
gttgcagctctcagaggatcccggaaatttaacattctgggcacaaacacaaaagtgatg
aacatggaagagtccaacaacggcagcctctctgcagaattcaaacacttgaccctgagg
gagcagagatgtgggaatgggggccgagccaattgtgatgcttccctgattgtgactgag
gagctgcacctgatcacctttgagacagaggtgtatcaccaaggcctcaagattgaccta
gaggtgaaccactccttgccagttgtggtgatctccaacatctgtcagatgccaaatgcc
tgggcgtccnntctgtggtacaacatgctgaccaacaatcccaagaacgtaaacnntttt
accaagcccccaatcggaacctgggatcaagtgggccgaggtcctgactggcagttctcc
tccaccaccaagcgaggacgagcatcgagcagctgacttacactggccagagaaaacttc
ttgggacctggcgtgaattattcagggtgtcagatcacatgggctaaattttgcaaagaa
aacatggctggcaagggcttctccttctgggtctggctggacaatatcattgaccttgtg
aaaaagtacatcctggccctttggaacgaagggtacatcatgggctttatcagtaaggaa
cgggagcgggccatcttgagcaccaagcctccaggcacctttctgctaagattcagtgaa
agcagcaaagaaggcggcgtcactttcacttgggtggagaaggacatcagtggtaagacc
cagatccagtccgtggaaccatacaccaagcagcagttgaacaacatgtcatttgctgaa
atcatcatgggctataagatcatggatgctaccaatattctggtgtctccgctggtctat
ctctaccctgacattcccaaggaggaggcatttggaaagtattgtcggccagagagccag
gagcatcctgaagctgacccaggcgccgccccatacctgaagaccaagtttatctgtgtg
acaccaacgacctgcagcaataccattgacctgccgatgtccccccgcactttagattca
ttgatgcagtttggaaataatggtgaaggtgctgaaccctcagcaggagggcagtttgag
tccctcacctttgacatggagttgacctcggagtgtgctacctcccccatgtga

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