Rhinopithecus bieti (black snub-nosed monkey): 108528282 Help Entry 108528282         CDS       T04641                                  Gene name TGFB2 Definition (RefSeq) transforming growth factor beta 2   KO K13376   transforming growth factor beta-2 Organism rbb  Rhinopithecus bieti (black snub-nosed monkey) Pathway rbb04010   MAPK signaling pathway rbb04060   Cytokine-cytokine receptor interaction rbb04068   FoxO signaling pathway rbb04110   Cell cycle rbb04218   Cellular senescence rbb04350   TGF-beta signaling pathway rbb04380   Osteoclast differentiation rbb04390   Hippo signaling pathway rbb04933   AGE-RAGE signaling pathway in diabetic complications rbb05140   Leishmaniasis rbb05142   Chagas disease rbb05144   Malaria rbb05145   Toxoplasmosis rbb05146   Amoebiasis rbb05152   Tuberculosis rbb05161   Hepatitis B rbb05166   Human T-cell leukemia virus 1 infection rbb05200   Pathways in cancer rbb05205   Proteoglycans in cancer rbb05206   MicroRNAs in cancer rbb05210   Colorectal cancer rbb05211   Renal cell carcinoma rbb05212   Pancreatic cancer rbb05220   Chronic myeloid leukemia rbb05225   Hepatocellular carcinoma rbb05226   Gastric cancer rbb05321   Inflammatory bowel disease rbb05323   Rheumatoid arthritis rbb05410   Hypertrophic cardiomyopathy rbb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rbb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     108528282 (TGFB2)    04350 TGF-beta signaling pathway     108528282 (TGFB2)    04390 Hippo signaling pathway     108528282 (TGFB2)    04068 FoxO signaling pathway     108528282 (TGFB2)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     108528282 (TGFB2)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     108528282 (TGFB2)    04218 Cellular senescence     108528282 (TGFB2)  09150 Organismal Systems   09158 Development and regeneration    04380 Osteoclast differentiation     108528282 (TGFB2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108528282 (TGFB2)    05206 MicroRNAs in cancer     108528282 (TGFB2)    05205 Proteoglycans in cancer     108528282 (TGFB2)   09162 Cancer: specific types    05210 Colorectal cancer     108528282 (TGFB2)    05212 Pancreatic cancer     108528282 (TGFB2)    05225 Hepatocellular carcinoma     108528282 (TGFB2)    05226 Gastric cancer     108528282 (TGFB2)    05220 Chronic myeloid leukemia     108528282 (TGFB2)    05211 Renal cell carcinoma     108528282 (TGFB2)   09163 Immune disease    05323 Rheumatoid arthritis     108528282 (TGFB2)    05321 Inflammatory bowel disease     108528282 (TGFB2)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     108528282 (TGFB2)    05414 Dilated cardiomyopathy     108528282 (TGFB2)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     108528282 (TGFB2)   09171 Infectious disease: bacterial    05152 Tuberculosis     108528282 (TGFB2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     108528282 (TGFB2)    05161 Hepatitis B     108528282 (TGFB2)   09174 Infectious disease: parasitic    05146 Amoebiasis     108528282 (TGFB2)    05144 Malaria     108528282 (TGFB2)    05145 Toxoplasmosis     108528282 (TGFB2)    05140 Leishmaniasis     108528282 (TGFB2)    05142 Chagas disease     108528282 (TGFB2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:rbb04052]     108528282 (TGFB2)    00536 Glycosaminoglycan binding proteins [BR:rbb00536]     108528282 (TGFB2) Cytokines and growth factors [BR:rbb04052]  Cytokines   Transforming growth factors (RSTK binding)    108528282 (TGFB2) Glycosaminoglycan binding proteins [BR:rbb00536]  Heparan sulfate / Heparin   Growth factors/receptors    108528282 (TGFB2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta SPEG_u2 Motif Other DBs NCBI-GeneID:  108528282 NCBI-ProteinID:  XP_017725506 UniProt:  A0A2K6JV81 LinkDB All DBs Position Un AA seq 442 aa AA seqDB search MHYCVLSAFLILHLVTVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEP EEVPPEVISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPPFFPSETVCPV VTTPSGSVGSLCSRQSQVLCGYLDAIPPTFYRPYFRIVRFDVSAMEKNASNLVKAEFRVF RLQNPKARVPEQRIELYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLH HKDRNLGFKISLHCPCCTFVPSNNYIIPNKSEELEARFAGIDGTSTYTSGDQKTIKSTRK KNSGKTPHLLLMLLPSYRLESQQTNRRKKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGW KWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILY YIGKTPKIEQLSNMIVKSCKCS NT seq 1329 nt NT seq  +upstreamnt  +downstreamnt atgcactactgtgtgctgagcgcttttctgatcctgcatctggtcacggtcgcgctcagc ctgtctacctgcagcacactcgatatggaccagttcatgcgcaagaggatcgaggcgatc cgcgggcagatcctgagcaagctgaagctcaccagtcccccagaagactatcctgagccc gaggaagtccccccggaggtgatttccatctacaacagcaccagggacttgctccaggag aaggcgagccggagggcggccgcctgcgagcgcgagaggagcgacgaggagtactacgcc aaggaggtttacaaaatagacatgccgcccttcttcccctccgaaactgtctgcccagtt gttacaacaccctctggctcagtgggcagcttgtgctccagacagtcccaggtgctctgt gggtaccttgatgccatcccgcccactttctacagaccctacttcagaattgttcggttt gacgtctcagcaatggagaagaatgcttccaatttggtgaaagcagagttcagagtcttt cgtttgcagaatccaaaagccagagtgcctgaacaacggattgagctgtatcagattctc aagtccaaagacttaacatctccaacccagcgctacattgacagcaaagttgtgaaaaca agagcagaaggcgaatggctttccttcgatgtaactgatgctgttcatgaatggcttcac cataaagacaggaacctgggatttaaaataagcttacattgtccctgctgcacttttgta ccatctaataattacatcatcccaaataaaagcgaagaactagaagcaagatttgcaggt attgatggcacctccacatataccagtggtgatcagaaaactataaagtccactaggaaa aaaaacagtgggaagaccccacatctcctgctaatgttattgccctcctacagacttgag tcacaacagaccaaccggcggaagaagcgtgctttggatgcggcctattgctttagaaat gtgcaggataattgctgcctacgtccactttacattgatttcaagagggatctagggtgg aaatggatacacgaacccaaagggtacaatgccaacttctgtgctggagcatgcccgtat ttatggagttcagacactcagcacagcagggtcctgagcttatataataccataaatcca gaagcatctgcttctccttgctgcgtgtcccaagatttagaacctctaaccattctctac tacattggcaaaacacccaagattgaacagctttctaatatgattgtaaagtcttgcaaa tgcagctaa

Rhinopithecus bieti (black snub-nosed monkey): 108534939 Help Entry 108534939         CDS       T04641                                  Gene name TGFB3 Definition (RefSeq) transforming growth factor beta 3   KO K13377   transforming growth factor beta-3 Organism rbb  Rhinopithecus bieti (black snub-nosed monkey) Pathway rbb04010   MAPK signaling pathway rbb04060   Cytokine-cytokine receptor interaction rbb04068   FoxO signaling pathway rbb04110   Cell cycle rbb04218   Cellular senescence rbb04350   TGF-beta signaling pathway rbb04390   Hippo signaling pathway rbb04933   AGE-RAGE signaling pathway in diabetic complications rbb05140   Leishmaniasis rbb05142   Chagas disease rbb05144   Malaria rbb05145   Toxoplasmosis rbb05146   Amoebiasis rbb05152   Tuberculosis rbb05161   Hepatitis B rbb05166   Human T-cell leukemia virus 1 infection rbb05200   Pathways in cancer rbb05210   Colorectal cancer rbb05211   Renal cell carcinoma rbb05212   Pancreatic cancer rbb05220   Chronic myeloid leukemia rbb05225   Hepatocellular carcinoma rbb05226   Gastric cancer rbb05321   Inflammatory bowel disease rbb05323   Rheumatoid arthritis rbb05410   Hypertrophic cardiomyopathy rbb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rbb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     108534939 (TGFB3)    04350 TGF-beta signaling pathway     108534939 (TGFB3)    04390 Hippo signaling pathway     108534939 (TGFB3)    04068 FoxO signaling pathway     108534939 (TGFB3)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     108534939 (TGFB3)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     108534939 (TGFB3)    04218 Cellular senescence     108534939 (TGFB3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108534939 (TGFB3)   09162 Cancer: specific types    05210 Colorectal cancer     108534939 (TGFB3)    05212 Pancreatic cancer     108534939 (TGFB3)    05225 Hepatocellular carcinoma     108534939 (TGFB3)    05226 Gastric cancer     108534939 (TGFB3)    05220 Chronic myeloid leukemia     108534939 (TGFB3)    05211 Renal cell carcinoma     108534939 (TGFB3)   09163 Immune disease    05323 Rheumatoid arthritis     108534939 (TGFB3)    05321 Inflammatory bowel disease     108534939 (TGFB3)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     108534939 (TGFB3)    05414 Dilated cardiomyopathy     108534939 (TGFB3)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     108534939 (TGFB3)   09171 Infectious disease: bacterial    05152 Tuberculosis     108534939 (TGFB3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     108534939 (TGFB3)    05161 Hepatitis B     108534939 (TGFB3)   09174 Infectious disease: parasitic    05146 Amoebiasis     108534939 (TGFB3)    05144 Malaria     108534939 (TGFB3)    05145 Toxoplasmosis     108534939 (TGFB3)    05140 Leishmaniasis     108534939 (TGFB3)    05142 Chagas disease     108534939 (TGFB3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:rbb04052]     108534939 (TGFB3) Cytokines and growth factors [BR:rbb04052]  Cytokines   Transforming growth factors (RSTK binding)    108534939 (TGFB3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta Motif Other DBs NCBI-GeneID:  108534939 NCBI-ProteinID:  XP_017736057 UniProt:  A0A2K6LSK0 LinkDB All DBs Position Un AA seq 412 aa AA seqDB search MKMHLQRALVVLALLNFASVSLSLSTCTTLDFGHIKKKRVEAIRGQILSKLRLTSPPEPT VMTHVPYQVLALYNSTRELLEEMHGEREEGCTQENTESEYYAKEIHKFDMIQGLAEHNEL AVCPKGITSKVFRFNVSSVEKNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQILRPDEHI AKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE NIHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKR ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPYLRSADTTHST VLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQLSNMVVKSCKCS NT seq 1239 nt NT seq  +upstreamnt  +downstreamnt atgaagatgcacttgcaaagggctctggtggtcctggcactgctgaactttgcctcggtc agcctctctctgtccacttgcaccaccttggacttcggccacatcaagaagaagagggtg gaagccattaggggacagatcttgagcaagctcaggctcaccagcccccctgagccaacg gtgatgacccacgtcccctatcaggtcctggccctttacaacagcacccgggagctgctg gaggagatgcatggggagagggaggaaggctgcacccaggaaaacaccgagtcggaatac tatgccaaagaaatccataaattcgacatgatccaggggctggcggagcacaacgaactg gctgtctgccccaaaggaattacctccaaggttttccgcttcaatgtgtcctcagtggag aaaaatagaaccaacctgttccgagcagaattccgggtcttgcgggtgcccaaccccagc tctaagcggaatgagcagaggatcgagctcttccagatccttcggccggatgagcacatt gccaaacagcgctatatcggtggcaagaatctgcccacacggggcactgccgagtggctg tcctttgatgtcactgacacagtgcgtgagtggctgttgagaagagagtccaacttaggt ctagaaatcagcattcactgtccatgtcacacctttcagcccaatggagatatcctggaa aacattcacgaggtgatggaaatcaaattcaaaggcgtggacaatgaggatgaccacggc cgtggagatctggggcgcctcaagaagcagaaggatcaccacaaccctcatctaatcctc atgatgattcccccacaccggctcgacaacccgggccaggggggtcagagaaagaagcgg gccttggacaccaattactgcttccgcaacttggaggagaactgctgtgtgcgccccctc tacattgacttccgacaggatctgggctggaagtgggtccatgaacctaagggctactat gccaacttctgctcaggcccttgcccatacctccgcagtgcagacacaacccacagcacg gtgctgggactgtacaacactctgaaccctgaagcatctgcctcgccttgctgcgtgccc caggacctggagcccctgaccatcctgtactatgttgggaggacccccaaggtggagcag ctctccaacatggtggtgaagtcttgtaaatgtagctga

Rhinopithecus bieti (black snub-nosed monkey): 108536158 Help Entry 108536158         CDS       T04641                                  Gene name TGFB1 Definition (RefSeq) transforming growth factor beta 1   KO K13375   transforming growth factor beta-1 Organism rbb  Rhinopithecus bieti (black snub-nosed monkey) Pathway rbb04010   MAPK signaling pathway rbb04060   Cytokine-cytokine receptor interaction rbb04068   FoxO signaling pathway rbb04110   Cell cycle rbb04218   Cellular senescence rbb04350   TGF-beta signaling pathway rbb04380   Osteoclast differentiation rbb04390   Hippo signaling pathway rbb04659   Th17 cell differentiation rbb04672   Intestinal immune network for IgA production rbb04926   Relaxin signaling pathway rbb04932   Non-alcoholic fatty liver disease rbb04933   AGE-RAGE signaling pathway in diabetic complications rbb05140   Leishmaniasis rbb05142   Chagas disease rbb05144   Malaria rbb05145   Toxoplasmosis rbb05146   Amoebiasis rbb05152   Tuberculosis rbb05161   Hepatitis B rbb05166   Human T-cell leukemia virus 1 infection rbb05200   Pathways in cancer rbb05205   Proteoglycans in cancer rbb05210   Colorectal cancer rbb05211   Renal cell carcinoma rbb05212   Pancreatic cancer rbb05220   Chronic myeloid leukemia rbb05225   Hepatocellular carcinoma rbb05226   Gastric cancer rbb05321   Inflammatory bowel disease rbb05323   Rheumatoid arthritis rbb05410   Hypertrophic cardiomyopathy rbb05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rbb00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     108536158 (TGFB1)    04350 TGF-beta signaling pathway     108536158 (TGFB1)    04390 Hippo signaling pathway     108536158 (TGFB1)    04068 FoxO signaling pathway     108536158 (TGFB1)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     108536158 (TGFB1)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     108536158 (TGFB1)    04218 Cellular senescence     108536158 (TGFB1)  09150 Organismal Systems   09151 Immune system    04659 Th17 cell differentiation     108536158 (TGFB1)    04672 Intestinal immune network for IgA production     108536158 (TGFB1)   09152 Endocrine system    04926 Relaxin signaling pathway     108536158 (TGFB1)   09158 Development and regeneration    04380 Osteoclast differentiation     108536158 (TGFB1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108536158 (TGFB1)    05205 Proteoglycans in cancer     108536158 (TGFB1)   09162 Cancer: specific types    05210 Colorectal cancer     108536158 (TGFB1)    05212 Pancreatic cancer     108536158 (TGFB1)    05225 Hepatocellular carcinoma     108536158 (TGFB1)    05226 Gastric cancer     108536158 (TGFB1)    05220 Chronic myeloid leukemia     108536158 (TGFB1)    05211 Renal cell carcinoma     108536158 (TGFB1)   09163 Immune disease    05323 Rheumatoid arthritis     108536158 (TGFB1)    05321 Inflammatory bowel disease     108536158 (TGFB1)   09166 Cardiovascular disease    05410 Hypertrophic cardiomyopathy     108536158 (TGFB1)    05414 Dilated cardiomyopathy     108536158 (TGFB1)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     108536158 (TGFB1)    04933 AGE-RAGE signaling pathway in diabetic complications     108536158 (TGFB1)   09171 Infectious disease: bacterial    05152 Tuberculosis     108536158 (TGFB1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     108536158 (TGFB1)    05161 Hepatitis B     108536158 (TGFB1)   09174 Infectious disease: parasitic    05146 Amoebiasis     108536158 (TGFB1)    05144 Malaria     108536158 (TGFB1)    05145 Toxoplasmosis     108536158 (TGFB1)    05140 Leishmaniasis     108536158 (TGFB1)    05142 Chagas disease     108536158 (TGFB1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03110 Chaperones and folding catalysts [BR:rbb03110]     108536158 (TGFB1)   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:rbb04052]     108536158 (TGFB1)    00536 Glycosaminoglycan binding proteins [BR:rbb00536]     108536158 (TGFB1) Chaperones and folding catalysts [BR:rbb03110]  Intramolecular chaperones   Others    108536158 (TGFB1) Cytokines and growth factors [BR:rbb04052]  Cytokines   Transforming growth factors (RSTK binding)    108536158 (TGFB1) Glycosaminoglycan binding proteins [BR:rbb00536]  Heparan sulfate / Heparin   Growth factors/receptors    108536158 (TGFB1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TGFb_propeptide TGF_beta Motif Other DBs NCBI-GeneID:  108536158 NCBI-ProteinID:  XP_017738192 UniProt:  A0A2K6K6F3 LinkDB All DBs Position Un AA seq 390 aa AA seqDB search MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEI YDKFKQSTHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKVEQHVELYQKYSNNSWR YLSNQLLAPSDSPEWLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSKDNTLQVDINGFT TGRRGDLATIHGMNRPFLLLMATPLERAQHLQSSRHRRALDTNYCFSSTEKNCCVRQLYI DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQA LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS NT seq 1173 nt NT seq  +upstreamnt  +downstreamnt atgccgccctccgggctgcggctgctgccgctgctgctaccgctgctgtggctactggtg ctgacgcctggccggccggccgcgggactatccacctgcaagactatcgacatggagctg gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc agccccccaagccagggggaggtgccgcccggcccgctgcccgaggccgtgctcgccctg tacaacagcacccgcgaccgggtggccggggagagtgcggagccggagcccgaaccggag gccgactactacgccaaggaggtcacccgcgtgctaatggtggaaacccacaacgaaatc tatgacaagttcaagcagagcacacacagcatatatatgttcttcaacacatcagagctc cgagaagcagtacctgaacctgtgttgctctcccgggcagagctgcgtctgctgaggctc aagttaaaagtggagcagcatgtggagctgtaccagaaatacagcaacaattcctggcga tacctcagcaaccagctgctggcgcccagcgactcgccggagtggttgtcttttgatgtc accggagttgtgcggcagtggttgagccgcggaggggaaattgagggctttcgccttagc gcccactgctcctgtgacagcaaagataacacactgcaagtggacatcaacgggttcact accggccgccgaggtgacctggccaccattcatggcatgaaccggcctttcctgcttctc atggccaccccgctggagagggcccaacatctgcaaagctcccggcaccgccgagccctg gacaccaactactgcttcagctccacggagaagaactgctgcgtgcggcagctgtatatt gacttccgcaaggacctcggctggaagtggatccacgagcccaagggctaccacgccaac ttctgcctggggccctgcccctacatttggagcctggacacccagtacagcaaggtcctg gccctgtacaaccagcataacccgggcgcctcggcggcgccgtgctgcgtgccgcaggcg ctggagccgctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctgtcc aacatgatcgtgcgctcctgcaaatgcagctga

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