KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108530364Help
Entry
108530364         CDS       T04641                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00010  Glycolysis / Gluconeogenesis
rbb00051  Fructose and mannose metabolism
rbb00052  Galactose metabolism
rbb00500  Starch and sucrose metabolism
rbb00520  Amino sugar and nucleotide sugar metabolism
rbb00524  Neomycin, kanamycin and gentamicin biosynthesis
rbb01100  Metabolic pathways
rbb01200  Carbon metabolism
rbb04066  HIF-1 signaling pathway
rbb04910  Insulin signaling pathway
rbb04930  Type II diabetes mellitus
rbb04973  Carbohydrate digestion and absorption
rbb05230  Central carbon metabolism in cancer
Module
rbb_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rbb_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    108530364 (HK1)
   00051 Fructose and mannose metabolism
    108530364 (HK1)
   00052 Galactose metabolism
    108530364 (HK1)
   00500 Starch and sucrose metabolism
    108530364 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    108530364 (HK1)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    108530364 (HK1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    108530364 (HK1)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    108530364 (HK1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    108530364 (HK1)
 09160 Human Diseases
  09161 Cancers: Overview
   05230 Central carbon metabolism in cancer
    108530364 (HK1)
  09167 Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    108530364 (HK1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rbb04131]
    108530364 (HK1)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     108530364 (HK1)
Membrane trafficking [BR:rbb04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    108530364 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 CSD
Motif
Other DBs
NCBI-GeneID: 108530364
NCBI-ProteinID: XP_017728678
LinkDB All DBs
Position
Un
AA seq 917 aa AA seqDB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KDMLLEVKKRMRAEMELGLRKQTHNNAAVKMLPSFVRSTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVATLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDRGLMCINMEWGAFGDNGCLDD
IRTQYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRTEASS
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctggcctattacttcacggagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctgtccgatgaaactctcatagatatcatg
actcgcttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca
gtcaagatgttgccaacattcgtaagatccattcccgatggctctgaaaagggagatttc
attgccctggatcttggtgggtcttcctttcgaattctccgggtgcaagtgaatcatgag
aaaaaccagaatgttcacatggagtccgaggtttatgacaccccagagaacatcgtgcac
ggcagtggaagccagctttttgatcatgttgctgagtgcctgggagatttcatggagaaa
aggaagatcaaggacaagaagttacctgtaggattcacattttcttttccttgccaacaa
tccaaaatagatgaggccatcctgatcacctggacaaagcgatttaaagcaagtggagtg
gaaggagcggatgtggtcaaactgcttaacaaagccatcaaaaagcgaggggactatgat
gccaacatcgtagctgtggtgaatgacacagtgggcaccatgatgacctgtggctatgac
gaccagcagtgtgaagtcggcctgatcatcggtactggcaccaatgcttgctacatggag
gaactgaggcacattgatctggtggaaggagacgaggggaggatgtgtatcaacacagaa
tggggagcctttggagacgatggatcattagaagacatccggacagagtttgaccgggag
atagaccggggatccctcaaccctggaaaacagctgtttgagaagatggtcagtggcatg
tacttgggagagctggttcgactgatcctggtcaagatggccaaggagggcctcttgttt
gaagggcggatcaccccagagctgctcaccagagggaagtttaacaccagtgatgtgtca
gccatcgaaaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccgtccgatgatgactgtgtctcagtccagcacgtttgcaccattgtctcgttt
cgctcagccaacctggtggctgccacactgggcgccatcttgaaccgcctgcgtgataac
aagggcacacccaggctgcggaccacggttggtgtcgacggatctctttacaagacgcac
ccacagtattcccggcgtttccacaagactctgaggcgcttggtgccggactccgatgtg
cgcttcctcctctcggagagtggcagcggcaagggggctgccatggtgacggcggtggcc
taccgcttggccgagcagcaccggcaaatagaggagaccctggctcatttccacctcacc
aaggacatgctgctggaggtgaagaagaggatgcgggccgagatggagctggggctgagg
aagcagacgcacaacaatgccgcggttaagatgctgccctccttcgtccggagtacccct
gacgggaccgagaatggtgacttcttggccctggatcttggaggaaccaatttccgtgtg
ctgctggtgaaaatccgtagtgggaaaaagagaacggtggaaatgcacaacaagatctac
gccattcctattgaaatcatgcagggcactggggaagagctgtttgatcacattgtctcc
tgcatctctgacttcctggactacatggggatcaaaggccctaggatgcctctgggcttc
acgttctcatttccctgccagcagacgagtctggacgcgggaatcttgatcacgtggaca
aagggttttaaggcaacagactgcgtgggccatgatgtagccaccttactaagggatgcg
ataaaaaggagagaggaatttgacctggacgtggtggctgtggtcaacgacacagtgggc
accatgatgacctgtgcttatgaggagcccacctgtgaggtcggactcattgttgggact
ggcagtaatgcctgctacatggaggagatgaagaacgtggagatggtggagggagaccgg
gggctgatgtgcatcaacatggagtggggggcctttggggacaatgggtgtctggatgat
atcaggacacagtacgacagactggtggatgaatattccctaaatgctgggaaacaaagg
tatgagaagatgatcagtggtatgtacctgggtgaaattgtccgcaacatcttaatcgac
ttcaccaagaagggattcctcttccgagggcagatctcagagccgctgaagacccggggc
atctttgagaccaagtttctctctcagatcgagagtgaccgattagcactgctccaggtc
cgggccatcctccagcagctgggtctgaatagcacctgcgatgacagtatcctcgtcaag
actgtgtgcggggtggtgtccaggagggctgcgcagctgtgtggcgcaggcatggctgcg
gtggtggataagatccgagagaacagaggactggaccgtctgaacgtgactgtgggagtg
gacgggacgctctacaagcttcatccgcacttctccagaatcatgcaccagacggtgaag
gaactatcaccaaaatgtaacgtgtccttcctcctgtctgaggatggcagcggcaaggga
gccgccctcatcacggccgtgggcgtgcggttacgcacagaggcaagcagctaa

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