KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108530366Help
Entry
108530366         CDS       T04641                                 

Gene name
HKDC1
Definition
(RefSeq) hexokinase domain containing 1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00010  Glycolysis / Gluconeogenesis
rbb00051  Fructose and mannose metabolism
rbb00052  Galactose metabolism
rbb00500  Starch and sucrose metabolism
rbb00520  Amino sugar and nucleotide sugar metabolism
rbb00524  Neomycin, kanamycin and gentamicin biosynthesis
rbb01100  Metabolic pathways
rbb01200  Carbon metabolism
rbb04066  HIF-1 signaling pathway
rbb04910  Insulin signaling pathway
rbb04930  Type II diabetes mellitus
rbb04973  Carbohydrate digestion and absorption
rbb05230  Central carbon metabolism in cancer
Module
rbb_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rbb_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:rbb00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    108530366 (HKDC1)
   00051 Fructose and mannose metabolism
    108530366 (HKDC1)
   00052 Galactose metabolism
    108530366 (HKDC1)
   00500 Starch and sucrose metabolism
    108530366 (HKDC1)
   00520 Amino sugar and nucleotide sugar metabolism
    108530366 (HKDC1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    108530366 (HKDC1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    108530366 (HKDC1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    108530366 (HKDC1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    108530366 (HKDC1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    108530366 (HKDC1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    108530366 (HKDC1)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     108530366 (HKDC1)
Membrane trafficking [BR:rbb04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    108530366 (HKDC1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1
Motif
Other DBs
NCBI-GeneID: 108530366
NCBI-ProteinID: XP_017728685
UniProt: A0A2K6K8J6
LinkDB All DBs
Position
Un
AA seq 917 aa AA seqDB search
MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQMFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETWHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGVDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDKVLALFRLT
QEQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGVSLPLGFT
FSFPCRQTSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGDEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRTILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgtttgcggtccacttgatggcattttacttcagcaagctgaaggaggatcagatcaag
aaggtggacaggttcctgtatcacatgcggctctccgatgacacccttttggacatcatg
aggcggttccgggccgagatggagaagggcttggcgaaggacaccaaccccacggccgcg
gtgaagatgctgcccaccttcgtcagggccattcctgatggttccgaaaatggggagttc
ctttccctggatctcggagggtccaagtttcgagtgctgaaggtgcaagtcgctgaagaa
gggaagcgacacgtgcagatggagagtcagttctacccaacgcccaatgaaatcatccgt
gggaacggcacagagctgtttgaatatgtagcagactgtctggcagatttcatgaagacc
aaagatttaaagcataagaaattgccccttggcctaactttttctttcccctgccgacag
actaaactggaagagggtgtcctgctttcatggacaaagaagtttaaggcacgaggagtt
caggacacggatgtggtgagccgtctgaccaaagccatgaggagacacaaggacatggac
gtggacatcctggccctggtcaatgacaccgtggggaccatgatgacctgtgcctatgac
gacccctactgcgaagttggtgtcatcatcggaactggcacaaatgcgtgttatatggag
gacatgagcaacattgacctggtggagggcgacgagggcaggatgtgcatcaacacagag
tggggggcctttggggacgacggggccctggaggacattcgcaccgagttcgacagggag
ctggacctcggctctctcaacccgggaaagcaaatgtttgagaagatgatcagtggcctg
tacctgggggagcttgtcaggcttatcttgctgaagatggccaaggctggcctcctgttc
ggcggtgagaaatcttctgctctccacactaagggcaagattgaaacatggcacgtggct
gccatggagaagtataaagaaggccttgccaatacaagagagatcctggtggacctgggc
ctggagccatctgaggctgactgcattgccgtccagcatgtctgtaccatcgtctccttc
cgctcggccaacctctgcgcagcagccctggcggccatcctgacacgcctccgggagaac
aagaaggtggaacggctccggaccacggtgggcgtggacggcaccctctacaagatacac
cctcagtacccaaaacgcctgcacaaggtggtgaggaaactggtcccgagctgtgatgtc
cgcttcctcctgtcagagagtggcagcaccaagggggccgccatggtgactgcagtggcc
tcccgcgtgcaggcccagcggaagcagatcgacaaggtgctggctttgttccggctgacc
caagagcagctcgtggacgtgcaggccaagatgcgggctgagctggagtacgggctgaag
aagaagagccacgggctggccacggtcagaatgctgcccacctacgtctgcgggctgccg
gacggcacagagaaaggaaagtttctcgccctggatcttgggggaaccaacttccgggtc
ctcctggtgaagatcagaagtggacggaggtcagtgcgaatgtacaacaagatcttcgcc
atccccctggagatcatgcagggcactggtgaggagctctttgaccacattgtgcagtgc
atcgccgacttcctggactacatgggcctcaagggagtctccctacctttgggcttcacg
ttctcatttccctgcaggcagacaagcattgacaagggaacactcatagggtggaccaaa
ggtttcaaggccactgactgtgaaggggaggacgtggtggacatgctcagggaagccatc
aagagaagaaacgagtttgacctggacatcgttgcagttgtgaatgatacagtggggacc
atgatgacctgtggctatgaagatcctaattgtgagattggcttgattgcaggaacaggc
agcaacatgtgctacatggaggacatgaggaacatcgagatggtggagggggatgaaggg
aagatgtgcatcaacacagagtggggaggatttggagacaatggctgcatagatgacatc
cggacccgatacgacacggaggtggacgaggggtccttgaatcctggcaagcagagatac
gagaaaatgaccagtgggatgtacttgggggagattgtgcggcagatcctgatcgacctg
accaagcagggtcttctcttccgagggcagatttcagagcgtctccggaccaggggcatc
ttcgaaaccaagttcctgtcccagattgaaagcgatcggctggccctcctccaggtcagg
acgattctgcagcagctgggcctggacagcacatgtgaggacagcatcgtggtgaaggag
gtgtgcggagctgtgtcccggagggcggcccagctctgtggtgctggcctggccgctata
gtggaaaaaaggagagaagaccaggggctggagcacctgaggatcactgtgggtgtggac
ggcaccctgtacaagcttcaccctcacttttctagaatattgcaggaaactgtgaaggaa
ctagcccctcgatgtgatgtgacattcatgctgtcagaagatggcagtggaaaaggggca
gcactgatcactgctgtggccaagaggttacagcaggcacagaaggagaactag

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