Rhinopithecus bieti (black snub-nosed monkey): 108532525
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Entry
108532525 CDS
T04641
Gene name
NOS3
Definition
(RefSeq) nitric oxide synthase 3
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00220
Arginine biosynthesis
rbb00330
Arginine and proline metabolism
rbb01100
Metabolic pathways
rbb04020
Calcium signaling pathway
rbb04022
cGMP-PKG signaling pathway
rbb04066
HIF-1 signaling pathway
rbb04071
Sphingolipid signaling pathway
rbb04151
PI3K-Akt signaling pathway
rbb04370
VEGF signaling pathway
rbb04371
Apelin signaling pathway
rbb04611
Platelet activation
rbb04915
Estrogen signaling pathway
rbb04921
Oxytocin signaling pathway
rbb04926
Relaxin signaling pathway
rbb04931
Insulin resistance
rbb04933
AGE-RAGE signaling pathway in diabetic complications
rbb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
108532525 (NOS3)
00330 Arginine and proline metabolism
108532525 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
108532525 (NOS3)
04371 Apelin signaling pathway
108532525 (NOS3)
04066 HIF-1 signaling pathway
108532525 (NOS3)
04020 Calcium signaling pathway
108532525 (NOS3)
04071 Sphingolipid signaling pathway
108532525 (NOS3)
04022 cGMP-PKG signaling pathway
108532525 (NOS3)
04151 PI3K-Akt signaling pathway
108532525 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
108532525 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
108532525 (NOS3)
04921 Oxytocin signaling pathway
108532525 (NOS3)
04926 Relaxin signaling pathway
108532525 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
108532525 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
108532525 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
108532525 (NOS3)
Enzymes [BR:
rbb01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
108532525 (NOS3)
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Ortholog
Paralog
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
HTH_15
Motif
Other DBs
NCBI-GeneID:
108532525
NCBI-ProteinID:
XP_017732105
UniProt:
A0A2K6MEG7
LinkDB
All DBs
Position
Un
AA seq
1205 aa
AA seq
DB search
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATSAPEPSRAPASLPPPAPEHSPPSSPLT
QPPEGPKFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPTP
EQLLSQARDFINQYYSSIKRSGSQAHQQRLQEVEAEVAATGTYQLRENELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEMHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPSSDT
TTNGP
NT seq
3618 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagcgtggcccaggaacctgggccaccctgtggcctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagccacctctgcccctgagcccagccgg
gccccggcatccctacccccgccagcgccagaacacagccctccgagctccccgctaacc
cagcccccagaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcgcc
tatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccacggaaactacagggccggccctcccccggccccccgacccct
gagcagctgctgagtcaggcccgggacttcatcaaccagtactacagctccatcaagagg
agcggctctcaggcccaccaacagcggcttcaagaggtggaagccgaggtggcagccaca
ggcacctaccagcttagggagaatgagctggtgttcggggccaagcaggcctggcgcaac
gctccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggac
tgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaaatacgccaccaac
cggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggccgaggagac
ttccgaatctggaacagccagctggtgcgctatgcgggctaccggcagcaggatggctct
gtgcggggggacccagccaacgtcgagatcaccgagctctgcattcagcacggctggacc
ccaggaaacggtcgctttgacgtgctgcccctgctgctccaggccccggatgagccccca
gaactcttccttctgccccctgagctggtccttgaggtgccactggagcaccccacgctg
gagtggtttgcagctctgggcctgcgctggtacgccctcccagcagtgtccaacatgctg
ctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcact
gagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggacgtggct
gtctgcatggacctggacacccggacaacttcgtccctatggaaagacaaggcagcggtg
gaaatcaacgtggccgtgctgcacagttaccagctggccaaagtcaccattgtggaccac
cacgccgccacagcctccttcatgaagcacctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccccatctcaggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtccccagccttccgctaccagccagacccctgg
aaggggagtgcggccaagggcactggcatcaccaggaagaagacctttaaagaagtggcc
aatgccgtgaagatctccgcctcactcatgggcaccgtgatggcgaagcgagtgaaggcg
acaatcctgtacggctccgagaccggccgggcccagagctacgcacagcagctggggaga
cttttccggaaggcttttgatccccgggtcctgtgtatggatgagtacgatgtggtgtcc
cttgaacacgagacgctggtgctggtggtaaccagcacattcgggaatggggatcccccg
gagaatggagagagctttgcagctgccctgatggagatgtctggtccctacaacagctcc
cctcggccagaacagcacaagagttataagatccgcttcaacagcatctcctgctcagac
ccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggg
gccctgggcacactcaggttctgtgtgttcgggctgggctcccgggcgtacccccatttc
tgtgcctttgctcgtgcggtggacacgcggctggaggaactgggcggggagcggctgctg
cagctgggccagggtgacgagctgtgtggccaggaggaggccttccgcggctgggcccag
gctgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaggctgccgcc
cgagacatcttcagccccaaaaggagttggaagcgccagaggtaccggctgagcacccag
gccgagggcctgcagttgctgccaggcctgatccacgtgcacaggcggaagatgttccag
gctacaattctctcagtggaaaacctacaaagcagcaagtccacgagggccaccatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggaccacataggt
gtctgcccacccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccg
cctgcgcccaccgaacccgtggcagtagagcaactggagaagggcagccctggtggccct
ccccccagctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcagctcttgcggctgctcagcaccttg
gcagaagagcccagggaacagcaggagctggaggccctcagtcaggatccccgacgctat
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccttcg
gtggcactgcctgccccactgctcctcacccagctgcctctgcttcaaccccggtactac
tcagtcagctcagcacccagcacccacccaggagagatgcacctcactgtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggcta
agccaactcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccacccgatcccagcttgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccact
cccatgactttggtgtttggctgccgatgctcccaactcgaccatctctaccgcgacgag
gtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaa
cctgacaaccccaagacctacgtgcaggacatcctgagaacggagctggctgcagaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcttggcgacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttc
gggctcacgctgcgcacccaagaggtgacaagccgcatacgcacccagagcttttccttg
caggagcggcagctgcggggcgcagtgccctgggcgttcgacccgcccagctccgacacc
accaccaacggcccctga
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integrated database retrieval system
