KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108532525
Entry
108532525         CDS       T04641                                 

Gene name
NOS3
Definition
(RefSeq) nitric oxide synthase 3
  KO
K13242  nitric-oxide synthase, endothelial [EC:1.14.13.39]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00220  Arginine biosynthesis
rbb00330  Arginine and proline metabolism
rbb01100  Metabolic pathways
rbb04020  Calcium signaling pathway
rbb04022  cGMP-PKG signaling pathway
rbb04066  HIF-1 signaling pathway
rbb04071  Sphingolipid signaling pathway
rbb04151  PI3K-Akt signaling pathway
rbb04370  VEGF signaling pathway
rbb04371  Apelin signaling pathway
rbb04611  Platelet activation
rbb04915  Estrogen signaling pathway
rbb04921  Oxytocin signaling pathway
rbb04926  Relaxin signaling pathway
rbb04931  Insulin resistance
rbb04933  AGE-RAGE signaling pathway in diabetic complications
rbb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    108532525 (NOS3)
   00330 Arginine and proline metabolism
    108532525 (NOS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    108532525 (NOS3)
   04371 Apelin signaling pathway
    108532525 (NOS3)
   04066 HIF-1 signaling pathway
    108532525 (NOS3)
   04020 Calcium signaling pathway
    108532525 (NOS3)
   04071 Sphingolipid signaling pathway
    108532525 (NOS3)
   04022 cGMP-PKG signaling pathway
    108532525 (NOS3)
   04151 PI3K-Akt signaling pathway
    108532525 (NOS3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108532525 (NOS3)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    108532525 (NOS3)
   04921 Oxytocin signaling pathway
    108532525 (NOS3)
   04926 Relaxin signaling pathway
    108532525 (NOS3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    108532525 (NOS3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    108532525 (NOS3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    108532525 (NOS3)
Enzymes [BR:rbb01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     108532525 (NOS3)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 HTH_15
Other DBs
NCBI-GeneID: 108532525
NCBI-ProteinID: XP_017732105
UniProt: A0A2K6MEG7
LinkDB
Position
Un
AA seq 1205 aa
MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATSAPEPSRAPASLPPPAPEHSPPSSPLT
QPPEGPKFPRVKNWEVGSIAYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPTP
EQLLSQARDFINQYYSSIKRSGSQAHQQRLQEVEAEVAATGTYQLRENELVFGAKQAWRN
APRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGD
FRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPP
ELFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMST
EIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDH
HAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPW
KGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGR
LFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSS
PRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHF
CAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAA
RDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATILSVENLQSSKSTRATIL
VRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPGGP
PPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPRRY
EEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEMHLTVAVL
AYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGIAP
FRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFSRE
PDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDMELD
EAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWAFDPPSSDT
TTNGP
NT seq 3618 nt   +upstreamnt  +downstreamnt
atgggcaacttgaagagcgtggcccaggaacctgggccaccctgtggcctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagccacctctgcccctgagcccagccgg
gccccggcatccctacccccgccagcgccagaacacagccctccgagctccccgctaacc
cagcccccagaggggcccaagttccctcgtgtgaagaactgggaggtggggagcatcgcc
tatgacaccctcagcgcccaggcgcagcaggatgggccctgcaccccaagacgctgcctg
ggctccctggtatttccacggaaactacagggccggccctcccccggccccccgacccct
gagcagctgctgagtcaggcccgggacttcatcaaccagtactacagctccatcaagagg
agcggctctcaggcccaccaacagcggcttcaagaggtggaagccgaggtggcagccaca
ggcacctaccagcttagggagaatgagctggtgttcggggccaagcaggcctggcgcaac
gctccccgctgtgtgggccggatccagtgggggaagctgcaggtgttcgatgcccgggac
tgcaggtctgcacaggaaatgttcacctacatctgcaaccacatcaaatacgccaccaac
cggggcaaccttcgctcggccatcacagtgttcccgcagcgctgccctggccgaggagac
ttccgaatctggaacagccagctggtgcgctatgcgggctaccggcagcaggatggctct
gtgcggggggacccagccaacgtcgagatcaccgagctctgcattcagcacggctggacc
ccaggaaacggtcgctttgacgtgctgcccctgctgctccaggccccggatgagccccca
gaactcttccttctgccccctgagctggtccttgaggtgccactggagcaccccacgctg
gagtggtttgcagctctgggcctgcgctggtacgccctcccagcagtgtccaacatgctg
ctggaaattgggggcctggagttccccgcagcccccttcagtggctggtacatgagcact
gagatcggcacgaggaacctgtgtgaccctcaccgctacaacatcctggaggacgtggct
gtctgcatggacctggacacccggacaacttcgtccctatggaaagacaaggcagcggtg
gaaatcaacgtggccgtgctgcacagttaccagctggccaaagtcaccattgtggaccac
cacgccgccacagcctccttcatgaagcacctggagaatgagcagaaggccagggggggc
tgccctgcagactgggcctggatcgtgccccccatctcaggcagcctcactcctgtcttc
catcaggagatggtcaactatttcctgtccccagccttccgctaccagccagacccctgg
aaggggagtgcggccaagggcactggcatcaccaggaagaagacctttaaagaagtggcc
aatgccgtgaagatctccgcctcactcatgggcaccgtgatggcgaagcgagtgaaggcg
acaatcctgtacggctccgagaccggccgggcccagagctacgcacagcagctggggaga
cttttccggaaggcttttgatccccgggtcctgtgtatggatgagtacgatgtggtgtcc
cttgaacacgagacgctggtgctggtggtaaccagcacattcgggaatggggatcccccg
gagaatggagagagctttgcagctgccctgatggagatgtctggtccctacaacagctcc
cctcggccagaacagcacaagagttataagatccgcttcaacagcatctcctgctcagac
ccactggtgtcctcttggcggcggaagaggaaggagtccagtaacacagacagtgcaggg
gccctgggcacactcaggttctgtgtgttcgggctgggctcccgggcgtacccccatttc
tgtgcctttgctcgtgcggtggacacgcggctggaggaactgggcggggagcggctgctg
cagctgggccagggtgacgagctgtgtggccaggaggaggccttccgcggctgggcccag
gctgccttccaggccgcctgtgagaccttctgtgtgggagaggatgccaaggctgccgcc
cgagacatcttcagccccaaaaggagttggaagcgccagaggtaccggctgagcacccag
gccgagggcctgcagttgctgccaggcctgatccacgtgcacaggcggaagatgttccag
gctacaattctctcagtggaaaacctacaaagcagcaagtccacgagggccaccatcctg
gtgcgcctggacactggaggccaggaggggctgcagtaccagccgggggaccacataggt
gtctgcccacccaaccggcccggccttgtggaggcgctgctgagccgcgtggaggacccg
cctgcgcccaccgaacccgtggcagtagagcaactggagaagggcagccctggtggccct
ccccccagctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctcacc
ttcttcctggacatcacctccccgcccagccctcagctcttgcggctgctcagcaccttg
gcagaagagcccagggaacagcaggagctggaggccctcagtcaggatccccgacgctat
gaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttcccttcg
gtggcactgcctgccccactgctcctcacccagctgcctctgcttcaaccccggtactac
tcagtcagctcagcacccagcacccacccaggagagatgcacctcactgtagctgtgctg
gcatacaggacccaggatgggctgggccccctgcactatggagtctgctccacgtggcta
agccaactcaagcccggagaccctgtgccctgcttcatccggggggctccctccttccgg
ctgccacccgatcccagcttgccctgcatcctggtgggcccaggcactggcattgccccc
ttccggggattctggcaggagcggctgcatgacattgagagcaaagggctgcagcccact
cccatgactttggtgtttggctgccgatgctcccaactcgaccatctctaccgcgacgag
gtgcagaacgcccagcagcgcggggtgtttggccgagtcctcaccgccttctcccgggaa
cctgacaaccccaagacctacgtgcaggacatcctgagaacggagctggctgcagaggtg
caccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgatgtcaccatggca
accaacgtcctgcagaccgtgcagcgcatcttggcgacggagggcgacatggagctggac
gaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctaccacgaagacattttc
gggctcacgctgcgcacccaagaggtgacaagccgcatacgcacccagagcttttccttg
caggagcggcagctgcggggcgcagtgccctgggcgttcgacccgcccagctccgacacc
accaccaacggcccctga

KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108539288
Entry
108539288         CDS       T04641                                 

Gene name
NOS1
Definition
(RefSeq) nitric oxide synthase 1
  KO
K13240  nitric-oxide synthase, brain [EC:1.14.13.39]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00220  Arginine biosynthesis
rbb00330  Arginine and proline metabolism
rbb01100  Metabolic pathways
rbb04020  Calcium signaling pathway
rbb04145  Phagosome
rbb04371  Apelin signaling pathway
rbb04713  Circadian entrainment
rbb04730  Long-term depression
rbb04926  Relaxin signaling pathway
rbb04970  Salivary secretion
rbb05010  Alzheimer disease
rbb05014  Amyotrophic lateral sclerosis
rbb05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    108539288 (NOS1)
   00330 Arginine and proline metabolism
    108539288 (NOS1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    108539288 (NOS1)
   04020 Calcium signaling pathway
    108539288 (NOS1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    108539288 (NOS1)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    108539288 (NOS1)
  09154 Digestive system
   04970 Salivary secretion
    108539288 (NOS1)
  09156 Nervous system
   04730 Long-term depression
    108539288 (NOS1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    108539288 (NOS1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108539288 (NOS1)
   05014 Amyotrophic lateral sclerosis
    108539288 (NOS1)
   05022 Pathways of neurodegeneration - multiple diseases
    108539288 (NOS1)
Enzymes [BR:rbb01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     108539288 (NOS1)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 PDZ PDZ_6 NAD_binding_1 PDZ_2
Other DBs
NCBI-GeneID: 108539288
NCBI-ProteinID: XP_017743361
LinkDB
Position
Un
AA seq 1337 aa
MEDHMFGVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGRPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTQPLGPPTKAVDLSHQPSAGKEQPLAVDGASGPGNGPQHAQDDGQEAGSLPHANGLAP
XAPGQDPAKKAARVGLQGRGENNELLKEIEPVLNLLTSGSRGVKGGAPAKTEMKDMGIQV
DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLNSTLETGCTEYICMGSIMLPSQHLRRPEDVRTKEQLF
PLAKEFIDQYYSSIKRFGSKAHMERLEEVNKEIETTSTYQLKDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHVKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSTLGDPANVQFTEICIQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDMRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVQ
EERKYPEPLRFFPRKGPPLPHGDTEVHGLAAARDSQHRSYKVRFNSVSSYSDSQKSSGDG
PDLRHNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELT
QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHE
DLVNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT
TPPTPLQLQQFASLATNEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQAD
EVVPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGGLQSSGCLLP
TPRPGELQLCLSSPREQ
NT seq 4014 nt   +upstreamnt  +downstreamnt
atggaggatcacatgttcggtgttcagcaaatccagcccaatgtcatttctgttcgtctt
ttcaagcgcaaagttgggggcctgggattcctggtgaaggagcgggtcagtaagccaccc
gtgatcatctccgacctgattcgtgggggcgccgcggagcagagtggcctcatccaggct
ggagacatcattcttgcggtcaacggccggcccttggtggacctgagctatgacagcgcc
ctggaggtactcagaggcattgcctccgagacccacgtggtcctcattctgaggggccct
gaaggcttcaccacgcacctggagaccacctttacaggtgatgggacccccaaaaccatc
cgggtgacacagcccctgggtcccccaaccaaagctgtggatctgtcccaccagccatcg
gccggcaaagaacaacccctggcagtggatggggcctcgggtcctgggaatgggcctcag
catgcccaagacgatgggcaggaggctggctcgctcccccatgccaacggcctggcccca
nnggccccaggccaggaccctgcaaagaaagcagccagagtcggcctccaaggcagaggg
gagaacaatgaactgctcaaggagatagagcctgtgctgaaccttctcaccagtgggagc
agaggggtcaagggaggggcacctgccaagacagagatgaaagatatgggaatccaggtg
gacagagatttggacggcaaatcacacaaacctctgcccctcggtgtggagaacgaccga
gtcttcaatgacctatgggggaagggcaatgtgcctgtcgtcctcaacaacccatattca
gagaaggagcagccccctgcctcaggaaaacagtcccccacaaagaatggcagcccctcc
aagtgtccacgcttcctcaaagtcaagaactgggagactgacgtggttctcactgacacc
ctccaccttaacagcacattggaaacgggatgcactgagtacatctgcatgggctccatc
atgcttccttctcagcatctacggaggcctgaagatgtccgcacaaaagaacagctcttc
cctctcgccaaagagtttattgatcaatactattcttcaattaaaagatttggctccaaa
gcccacatggaaaggctggaagaggtgaacaaagagatcgaaaccactagcacctaccaa
ctcaaggacacagagctcatctacggggccaagcatgcctggcggaatgcctcgcgctgt
gtgggcaggatccagtggtccaagctgcaggtattcgatgctcgcgactgcaccacagcc
cacgggatgttcaactacatctgcaaccacgtcaagtatgccaccaataaagggaacctc
aggtctgccatcaccatattcccccagaggacagacggcaagcacgacttccgagtctgg
aactcccagctcatccgctacgctggctacaagcagcccgacggctccaccctgggggac
ccggccaacgtgcagttcacagagatttgcatacagcagggctggaaacccccgagaggc
cgcttcgatgtcctgccgctcctgcttcaggccaacggcaatgaccctgagctcttccag
attcctccagagctggtgttggaagttcccatcaggcaccccaagtttgagtggttcaag
gacctggggctgaagtggtacggcctccctgccgtgtccaacatgctcctggagattggc
ggcctggagttcagcgcctgtcccttcagtggctggtacatgggcacagagattggtgtc
cgcgactactgtgacaactcccgctacaatatcctggaggaagtggccaagaagatgaac
ttagacatgaggaagacgtcctccctgtggaaggaccaggcgctggtggagatcaatatc
gcggttctctatagcttccagagtgacaaagtgaccattgttgaccatcactccgccacc
gagtccttcattaagcacatggagaatgagtaccgctgccggggaggctgccctgccgac
tgggtgtggattgtgccccccatgtccggaagcatcacccctgtgttccaccaggagatg
ctcaactaccggctcaccccctccttcgaataccagcctgatccctggaacacccacgtc
tggaaaggcaccaacgggacccccacaaagcggcgagccattggcttcaagaagctggca
gaagctgtcaagttctcggccaagctaatggggcaggctatggccaagagggtcaaagca
accatcctctatgccacggagacaggcaaatcacaagcttatgccaagaccttgtgtgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacatcgtgcac
ctggaacatgaaactctggtcctcgtggttaccagcacctttggcaacggagatccccct
gagaatggggagaaatttggctgtgctttgatggaaatgaggcaccccaactctgtgcag
gaagaaaggaagtacccggaacccttgcgtttctttccccgtaaagggcctcccctcccc
catggtgacacagaagtccacggtctggctgcagcccgtgacagccagcacaggagctac
aaggtccgattcaatagcgtctcctcctactctgactcccaaaaatcatcaggcgatggg
cccgacctcagacacaactttgagagtgctggacccctggccaatgtgaggttctcagtg
tttggtcttggctcacgagcgtaccctcacttttgcgccttcggacatgctgtggacact
ctcctggaagaactgggaggggagaggatcctgaagatgagggaaggggatgagctctgt
gggcaggaagaggctttcaggacctgggccaagaaggtcttcaaggcagcctgtgatgtc
ttctgtgtgggagatgatgtcaacattgaaaaggcgaacaattccctcatcagcaatgac
cgcagctggaagagaaacaagttccgcctcacctatgtggccgaagctccagaactcacg
caaggtctatccaatgtccacaaaaagcgagtctcagctgcccgactccttagccgtcaa
aacctccagagccctaaatccagtcggtcaactatcttcgtgcgtctccacaccaacggg
agtcaggagctgcagtaccagcctggggaccacctgggtgtcttccctggcaaccacgag
gacctcgtgaatgccctgatcgagcggctggaggacgcaccccctgtcaaccagatggtg
aaagtggagctgctggaggagcggaacacggctttaggcgtcatcagtaactggacagac
gagcaccgcctcccaccctgcaccatcttccaggccttcaagtactacctggacatcacc
acgccaccaacgcccctgcagctgcagcagtttgcctccctagccaccaacgagaaggag
aagcagcgtctgctggtcctcagcaagggtttgcaggagtacgaggaatggaaatggggc
aagaaccccaccatcgtggaggtgctggaggagttcccatccatccagatgccggccacc
ttgctcctgacccagctgtccctgctgcagccccgctactattccatcagctcctcccca
gacatgtaccctgatgaagtgcacctcactgtggccatcgtttcctaccgcactcgagat
ggagaaggaccaattcaccacggcgtgtgctcctcctggctcaaccggatacaggctgac
gaagtggtcccctgtttcgtgagaggagcacccagcttccacctgccccggaacccccaa
gtcccttgcatccttgttggaccgggcaccggcattgcgcctttccgaagcttctggcaa
cagcggcaatttgatatccaacacaaaggtgggttacagtccagcggctgcctgcttccc
acccccagacctggggagctccagctgtgtctcagcagccctagagaacagtga

KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108539959
Entry
108539959         CDS       T04641                                 

Gene name
NOS2
Definition
(RefSeq) nitric oxide synthase 2
  KO
K13241  nitric-oxide synthase, inducible [EC:1.14.13.39]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00220  Arginine biosynthesis
rbb00330  Arginine and proline metabolism
rbb01100  Metabolic pathways
rbb04020  Calcium signaling pathway
rbb04066  HIF-1 signaling pathway
rbb04146  Peroxisome
rbb04371  Apelin signaling pathway
rbb04926  Relaxin signaling pathway
rbb05010  Alzheimer disease
rbb05014  Amyotrophic lateral sclerosis
rbb05022  Pathways of neurodegeneration - multiple diseases
rbb05133  Pertussis
rbb05140  Leishmaniasis
rbb05142  Chagas disease
rbb05145  Toxoplasmosis
rbb05146  Amoebiasis
rbb05152  Tuberculosis
rbb05200  Pathways in cancer
rbb05222  Small cell lung cancer
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    108539959 (NOS2)
   00330 Arginine and proline metabolism
    108539959 (NOS2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    108539959 (NOS2)
   04066 HIF-1 signaling pathway
    108539959 (NOS2)
   04020 Calcium signaling pathway
    108539959 (NOS2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    108539959 (NOS2)
 09150 Organismal Systems
  09152 Endocrine system
   04926 Relaxin signaling pathway
    108539959 (NOS2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108539959 (NOS2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    108539959 (NOS2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    108539959 (NOS2)
   05014 Amyotrophic lateral sclerosis
    108539959 (NOS2)
   05022 Pathways of neurodegeneration - multiple diseases
    108539959 (NOS2)
  09171 Infectious disease: bacterial
   05133 Pertussis
    108539959 (NOS2)
   05152 Tuberculosis
    108539959 (NOS2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    108539959 (NOS2)
   05145 Toxoplasmosis
    108539959 (NOS2)
   05140 Leishmaniasis
    108539959 (NOS2)
   05142 Chagas disease
    108539959 (NOS2)
Enzymes [BR:rbb01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     108539959 (NOS2)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1
Other DBs
NCBI-GeneID: 108539959
NCBI-ProteinID: XP_017744419
LinkDB
Position
Un
AA seq 901 aa
MREGLGAACEAAGPRLCRLLCRILRPKPACCLRGASPVTQDDLQYHSLSKQQNESLQPLV
GTGKKSPESLVKPDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMT
PKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQL
TGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARNCSTAREMFEHICRHVRYSTNNGNIR
SAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGR
FDVVPLVLQADGHDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGG
LEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVVEINIA
VLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEML
NYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKMMASRVRVTI
LFATETGKSEALAWDLGALFSCAFNPKVVCMDKYSLSCLEEERLLLVVTSTFGNGDCPGN
GEKLKKSLFMLKELTNKFRYAVFGLGSSMYPRFCAFARDIDQKLSHLGASQLTPMGEGDE
LSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSSVTWDPHHYRLVQDSQPLDLS
KALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGICPGNQP
ALVQGILERVVDSPAPHQIVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQL
LLQKLAQVATEVTERQRLEALCQVKIRVGGQCGYVGGLRMWGAGAQSWSLTSKRDPPRFP
K
NT seq 2706 nt   +upstreamnt  +downstreamnt
atgcgcgaggggttgggcgcggcgtgcgaggccgctgggccccggctttgccggctgctt
tgcaggatcctccggccgaagcccgcctgctgcctgcgcggagccagtccagtgacacag
gatgaccttcagtatcacagcctcagcaagcagcagaatgagtccctgcagcccctcgtg
gggacaggaaagaagtctccagaatctctggtcaagccggatgcaaccccattgtcctcc
ccacgacatgtgaggatcaaaaactggggcagcgggatgactttccaggacacacttcac
cacaaggccaaagggattttgacttgcaggtccaaatcttgcttgggatccattatgact
cccaaaagtttgaccagaggacccagggacaagcctacccctccagatgagcttctacct
caagctatcgaatttgtcaaccaatattacggctccttcaaagaggcaaaaatagaggaa
catctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctaccaactg
acgggagatgagctcatcttcgctaccaagcaggcctggcgcaatgccccacgctgcatt
gggaggatccagtggtccaacctgcaggtctttgatgcccgcaactgttccaccgcccgg
gaaatgtttgaacacatctgcagacacgtgcgttactccaccaacaatggcaacatcagg
tcggccatcaccgtgttcccccagcggagcgatggtaagcacgacttccgggtgtggaat
gctcagctcatccgctacgcgggctaccagatgccagatggcagcatcagaggggaccct
gccaacgtggaattcactcagctgtgcatcgacctgggctggaagcccaagtatggccgc
ttcgatgtggtccccctggtcctacaggctgacggccatgaccctgagctcttcgaaatc
ccacctgaccttgtgcttgaggtggccatggaacatcccaaatatgagtggtttcgggaa
ctggagctaaagtggtacgccctgcctgcagtggccaacatgctgctcgaggtgggcggc
ctggagttcccagggtgccccttcaatggctggtacatgggcacagagatcggagtccgg
gacttctgtgacgtccagcgctacaacatcctggaggaagtgggcaggagaatgggcttg
gaaacgcacaagctggcctcgctctggaaagaccgggctgttgttgagatcaacattgct
gtgctccatagtttccagaagcaaaacgtgaccatcatggaccaccactcagctgcagaa
tccttcatgaagtacatgcagaatgaataccggtcccgtgggggctgcccggcagactgg
atttggctggtccctcccatgtctgggagcatcactcccgtgtttcaccaggagatgctg
aactacgtcctgtcccctttctactactatcaggtagaggcctggaaaacccatgtctgg
caggacgagaagcggagacccaagagaagagagattccgttgaaagtcttggtcaaagct
gtgctcttcgcctgtatgctgatgcgcaagatgatggcgtcccgagtcagagtcaccatc
ctctttgcgacagagacaggaaaatcagaggcgctggcctgggacctgggggccttgttc
agctgtgccttcaaccccaaggttgtctgcatggataagtacagcctgagctgcctggag
gaggagcggctgctgttggtggtgaccagtacgtttggcaatggagactgccccggcaac
ggagagaaactgaagaaatcgctcttcatgctgaaagagctcaccaacaaattcaggtat
gctgtgtttggccttggctccagcatgtaccctcggttctgcgcctttgctcgtgacatc
gatcagaagctgtcccacctgggggcctctcagctcacccccatgggagaaggggatgag
ctcagtgggcaggaggacgccttccgcagctgggccgtgcaaaccttcaaggcagcctgt
gagacgtttgatgtccgaggcaaacagcacattcagatccccaagctctacacctccagt
gtgacctgggacccacaccactacaggctcgtgcaggactcacagcctttggacctcagc
aaagccctcagcagcatgcacgccaagaacgtgttcaccatgaggctcaaatctcggcag
aacctacagagtccgacatccagccgtgccaccatcctggtggaactctcctgtgaggac
ggccaaggcctgaactacttgccaggggagcaccttgggatttgcccaggcaaccagccg
gccctggtccaaggcatcctggagcgagtggtggacagccccgcgccccaccagatagtg
cgcctggaggccctggacgagagcggcagctactgggtcagtgacaagaggctgcccccc
tgctcactcagccaggccctcacctacttcctggatatcaccacccccccaacccagctg
ctgctccaaaagctggcccaggtggccacagaagtgactgagagacagaggctggaggcc
ctgtgccaggtgaagatcagggttggtgggcagtgcgggtatgtggggggtctcagaatg
tggggagctggagctcagagctggtctttaacttccaagagggatccacccaggttccca
aagtga

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