KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108542024
Entry
108542024         CDS       T04641                                 

Gene name
PTPN6
Definition
(RefSeq) protein tyrosine phosphatase, non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04520  Adherens junction
rbb04630  JAK-STAT signaling pathway
rbb04650  Natural killer cell mediated cytotoxicity
rbb04660  T cell receptor signaling pathway
rbb04662  B cell receptor signaling pathway
rbb05140  Leishmaniasis
rbb05205  Proteoglycans in cancer
rbb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    108542024 (PTPN6)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    108542024 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    108542024 (PTPN6)
   04660 T cell receptor signaling pathway
    108542024 (PTPN6)
   04662 B cell receptor signaling pathway
    108542024 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    108542024 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    108542024 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    108542024 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:rbb01009]
    108542024 (PTPN6)
Enzymes [BR:rbb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     108542024 (PTPN6)
Protein phosphatases and associated proteins [BR:rbb01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    108542024 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc Y_phosphatase3 PTPlike_phytase
Other DBs
NCBI-GeneID: 108542024
NCBI-ProteinID: XP_017747275
LinkDB
Position
Un
AA seq 670 aa
MQRPCSRAEVSMVASWLGPVARTRVTSRSLSGRWAPPPPAFSPLSCAIQAQNHSFLVPHG
SANSLIPTPRLCPRPSPLSSPSLSVPTHAHVCPHPGPQPIPALLPYSCTDWPHRLVPCRV
GDQVTHIRIQNSGDFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDP
TSERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVT
HIKVMCEGGRYTVGGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIEN
RVLELNKKKQSEDTAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKGKNRYKNILPFDHS
RVILQGRDSNIPGSDYINANYIKNQLLGPDENTKTYIASQGCLEATVNDFWQMAWQENTR
VIVMTTREVEKGRNKCVPYWPEVGTQRVYGPYSVTNCGEHDTTEYKLRTLQVSPLDNGDL
IREIWHYQYLSWPDHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIV
IDMLMENISTKGLDCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEV
LQSQKGQESEYGNITYPPAMKNAHAKASRTSSKHKEDVYENLHSKNKREEKVKKQRSADK
EKSKGSLKRK
NT seq 2013 nt   +upstreamnt  +downstreamnt
atgcagagaccctgctcaagggccgaggtgtccatggtagcttcctggctcggcccagtc
gcaagaaccagggtgacttctcgctctctgtcaggtaggtgggcccccccacccccggcg
ttttcgccactatcttgtgccatccaggcccagaaccactcattcctggttccccatggc
agtgccaactccctgatccccacgccccgtctgtgccctcgcccctcacccctgtcctcc
ccatccctgtctgtgcccacccatgcccatgtgtgcccccacccaggacctcagccgatc
cctgccctcctgccttactcctgcaccgactggcctcaccgcctggtgccctgcagggtg
ggggatcaggtgacccatattcggatccagaactcaggggacttctatgacctgtatgga
ggggagaagttcgcgacgctgacagagctggtggagtactacactcagcagcagggcgtc
ctgcaggaccgcgacggcaccatcatccacctcaagtacccgctgaactgctccgatcct
accagtgagaggtggtaccatggccacatgtctggagggcaggcagagacgctgctgcag
gccaagggcgagccctggacgtttcttgtgcgtgagagcctcagccagcccggagatttt
gtgctatctgtgctcagtgaccagcccaaggctggcccaggctccccgctcagggtcacc
cacatcaaggtcatgtgtgagggtggacgctacacagtgggtggttcagagaccttcgac
agcctcacggacctggtggagcacttcaagaagacgggaattgaggaggcctcaggtgcc
tttgtctacctgcggcagccgtactacgccacgagggtgaatgcggctgacattgagaac
cgagtcttggaactgaacaagaagaagcagtccgaggatacagccaaggctggcttctgg
gaggagtttgagagtttgcagaagcaggaggtgaagaacttgcaccagcgtctggaaggg
cagcggccagagaacaagggcaagaaccgctacaagaacattctgccctttgaccacagc
cgagtgatcctgcagggacgtgacagtaacatccctgggtccgactacatcaatgccaac
tacatcaagaaccagctgctaggccctgatgagaacactaagacctacatcgccagccaa
ggctgtctagaggccacggtcaatgacttctggcagatggcgtggcaggagaacacccgc
gtcatcgtcatgaccacccgagaggtggagaaaggccggaacaaatgtgtcccatactgg
cccgaggtgggcactcagcgcgtttatgggccctactctgtgaccaactgcggggagcat
gacacgaccgaatacaaactccgcaccttacaggtctccccactggacaatggggacctg
attcgggagatctggcattaccagtacctgagctggcccgaccatggggtccccagtgag
cctgggggtgtcctcagcttcctggaccagatcaaccagcggcaggaaagtctgcctcat
gcagggcccatcatcgtacactgcagcgccggcattggccgcacgggcaccatcattgtc
atcgacatgctcatggagaacatctccaccaagggcctggactgtgacattgacatccag
aagaccatccagatggtgcgggcgcagcgctcgggcatggtgcagacagaggcgcagtac
aagttcatctacgtggccattgcccagttcattgaaaccaccaagaagaagctggaggtc
ctacagtcgcagaagggccaggagtcggagtacgggaacatcacctaccccccagccatg
aagaacgcccatgccaaggcctcccgcacctcgtccaaacacaaggaggatgtgtatgag
aacctgcacagtaagaacaagagggaggagaaagtgaagaagcagcggtcagcagacaag
gagaagagcaagggttccctcaagaggaagtga

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