KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108543021
Entry
108543021         CDS       T04641                                 

Gene name
ADCY3
Definition
(RefSeq) adenylate cyclase 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00230  Purine metabolism
rbb01100  Metabolic pathways
rbb01522  Endocrine resistance
rbb04015  Rap1 signaling pathway
rbb04020  Calcium signaling pathway
rbb04022  cGMP-PKG signaling pathway
rbb04024  cAMP signaling pathway
rbb04062  Chemokine signaling pathway
rbb04072  Phospholipase D signaling pathway
rbb04114  Oocyte meiosis
rbb04211  Longevity regulating pathway
rbb04213  Longevity regulating pathway - multiple species
rbb04261  Adrenergic signaling in cardiomyocytes
rbb04270  Vascular smooth muscle contraction
rbb04371  Apelin signaling pathway
rbb04540  Gap junction
rbb04611  Platelet activation
rbb04713  Circadian entrainment
rbb04714  Thermogenesis
rbb04723  Retrograde endocannabinoid signaling
rbb04724  Glutamatergic synapse
rbb04725  Cholinergic synapse
rbb04727  GABAergic synapse
rbb04740  Olfactory transduction
rbb04750  Inflammatory mediator regulation of TRP channels
rbb04911  Insulin secretion
rbb04912  GnRH signaling pathway
rbb04913  Ovarian steroidogenesis
rbb04914  Progesterone-mediated oocyte maturation
rbb04915  Estrogen signaling pathway
rbb04916  Melanogenesis
rbb04918  Thyroid hormone synthesis
rbb04921  Oxytocin signaling pathway
rbb04923  Regulation of lipolysis in adipocytes
rbb04925  Aldosterone synthesis and secretion
rbb04926  Relaxin signaling pathway
rbb04927  Cortisol synthesis and secretion
rbb04928  Parathyroid hormone synthesis, secretion and action
rbb04934  Cushing syndrome
rbb04935  Growth hormone synthesis, secretion and action
rbb04962  Vasopressin-regulated water reabsorption
rbb04970  Salivary secretion
rbb04971  Gastric acid secretion
rbb04972  Pancreatic secretion
rbb04976  Bile secretion
rbb05032  Morphine addiction
rbb05163  Human cytomegalovirus infection
rbb05166  Human T-cell leukemia virus 1 infection
rbb05200  Pathways in cancer
rbb05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    108543021 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    108543021 (ADCY3)
   04371 Apelin signaling pathway
    108543021 (ADCY3)
   04020 Calcium signaling pathway
    108543021 (ADCY3)
   04072 Phospholipase D signaling pathway
    108543021 (ADCY3)
   04024 cAMP signaling pathway
    108543021 (ADCY3)
   04022 cGMP-PKG signaling pathway
    108543021 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    108543021 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    108543021 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    108543021 (ADCY3)
   04062 Chemokine signaling pathway
    108543021 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    108543021 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    108543021 (ADCY3)
   04912 GnRH signaling pathway
    108543021 (ADCY3)
   04913 Ovarian steroidogenesis
    108543021 (ADCY3)
   04915 Estrogen signaling pathway
    108543021 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    108543021 (ADCY3)
   04921 Oxytocin signaling pathway
    108543021 (ADCY3)
   04926 Relaxin signaling pathway
    108543021 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    108543021 (ADCY3)
   04918 Thyroid hormone synthesis
    108543021 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    108543021 (ADCY3)
   04916 Melanogenesis
    108543021 (ADCY3)
   04925 Aldosterone synthesis and secretion
    108543021 (ADCY3)
   04927 Cortisol synthesis and secretion
    108543021 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    108543021 (ADCY3)
   04270 Vascular smooth muscle contraction
    108543021 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    108543021 (ADCY3)
   04971 Gastric acid secretion
    108543021 (ADCY3)
   04972 Pancreatic secretion
    108543021 (ADCY3)
   04976 Bile secretion
    108543021 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    108543021 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    108543021 (ADCY3)
   04727 GABAergic synapse
    108543021 (ADCY3)
   04725 Cholinergic synapse
    108543021 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    108543021 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    108543021 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    108543021 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    108543021 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    108543021 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    108543021 (ADCY3)
   04714 Thermogenesis
    108543021 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    108543021 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    108543021 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    108543021 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    108543021 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    108543021 (ADCY3)
   05163 Human cytomegalovirus infection
    108543021 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    108543021 (ADCY3)
Enzymes [BR:rbb01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     108543021 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA RAP1 OPA3 Peptidase_S49_N
Other DBs
NCBI-GeneID: 108543021
NCBI-ProteinID: XP_017748816
UniProt: A0A2K6LDX0
LinkDB
Position
Un
AA seq 1145 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSEKLAPLAVAGIGLVLDII
LFVLCKKGLLPDRVTRRVVPYLLWLLITAQIFSYLGLNFTRAHAASDTVGWQVFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVG
IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD
YLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHS
SGSTSEKPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA
QVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN
YVTFVVGETLLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN
VVDMLSCLQYYTGPSNATAGMETEGGCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM
LLVAGAVAAINLYAWRPVFDEYDHRRFREHDSLPMVTLEKMQGFTPGLNGTDGLPLVPSK
YSMMVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPATFPNGPSVTLPHQ
VVDNS
NT seq 3438 nt   +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctccgagcccgagtactcggccgagtactcagccgagtac
tccgtcagcctgccctccgaccctgaccgcggggtgggccggacccatgaaatctcggtc
cggaactcgggctcctgcctgtgcctgcctcgcttcatgcggctgaccttcgtgccggag
tccttggagaacctctaccagacctacttcaaaaggcagcgccacgagaccctgctggtg
ctggtggtctttgctgccctctttgactgctacgtggtggtcatgtgtgctgtggtcttc
tccagcgagaagctggcccccctcgccgtggctggaattggactggtgttggacatcatc
ctcttcgtgctctgcaaaaaggggctgctcccggaccgggtcacccgcagagtggtgccc
tacctgctgtggctgctcataactgcccagatcttctcttacctgggcctgaacttcacg
cgtgcccacgcggccagtgacaccgtgggctggcaggtcttcttcgtcttctccttcttc
atcacgctgcccctcagcctcagccccatcgtgataatctccgtggtctcctgtgtggtg
cacaccttggtcttgggggtcactgtggcccagcagcagcaggaggagctgaaggggatg
cagctgctgcgggagatcctggccaacgtcttcctctacctgtgcgccatcgctgtgggc
atcatgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccag
tcgctggaggtgaagatgaacctggaagagcagagccagcagcaggagaacctcatgctt
tccatcctgcccaagcacgtggctgacgagatgctgaaagacatgaagaaagacgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc
ctctttgccgacatcgtgggctttacccagctgtcttctgcctgcagtgcccaggagctc
gtgaagctgctcaacgagctctttgcccgctttgacaagctggcagctaaataccaccag
cttcggattaagatcctgggtgactgctactactgcatctgcggcctgcctgactaccgt
gaggaccacgccgtctgctccatcctcatggggcttgccatggtggaagccatctcgtat
gtgcgggagaagaccaagactggggtggacatgcgtgtgggggtgcacacgggcaccgtg
ctggggggcgtcctgggccagaagcgctggcagtacgatgtgtggtcgactgacgtcact
gtagccaacaagatggaggccggcggcatccctgggcgcgttcacatctcccagagcacc
atggactgcctgaaaggggagtttgatgtggaaccaggcgatgggggcagccgctgtgat
tacctagaagagaagggtattgaaacctacctcatcattgcctccaagccagaggtgaag
aaaacagccacccagaatggcctcaatggctcggccctgcccaatggagcaccagcttcc
tcaaagtccagctcccctgccctcattgagaccaaggagcccaacgggagtgcccacagc
agcgggtccacgtcggagaaacccgaggagcaggatgcccaggccgacaacccctcattc
cccaacccgcgccggaggctgcgcctgcaggacctggctgaccgagtggtggacgcctcc
gaagacgagcacgagctcaaccagctgctcaacgaggccctgctcgagcgagagtctgcc
caagtagtaaagaagagaaacaccttcctcctgtccatgcggttcatggaccctgagatg
gaaacccgctactcggtggagaaggagaagcagagtggggctgccttcagctgctcctgt
gtcgtcctgctctgcacggctctggttgagatactcatcgacccctggctaatgacaaac
tatgtgaccttcgtggtgggggagactctgctcctcatcctgaccatctgctccctggct
gccatctttccccgggcctttcctaagaagcttgtggccttctcgacttggattgaccgg
acccgctgggccaggaacacctgggccatgctcgccatcttcatcctggtgatggcaaat
gtcgtggacatgctcagctgtctccagtactacacaggacccagcaacgcgacagcaggg
atggagacagagggcggctgcctggagaaccccaagtattacaactacgtggccgtgctg
tctctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacactcatg
ctgctcgtcgcgggcgccgtggccgccatcaacctctacgcctggcgccccgtcttcgat
gaatacgaccacaggcgttttcgggagcatgacagcttacctatggtgaccttagagaag
atgcagggattcacccctgggctcaacggcactgacgggctgcccctggtgccttccaag
tactccatgatggtgatggtgttcctcatgatgctgagcttctactacttctcccgccac
gtagaaaaactggcacggacgcttttcttgtggaagattgaggtccacgaccagaaggaa
cgtgtctatgagatgcgacgctggaacgaggccttggtcaccaacatgttgcctgagcac
gtggcacgccatttcctgggatccaagaagagagatgaggagctgtacagccagacgtat
gatgagattggagtcatgtttgcctccctgcccaactttgctgacttctacacagaggag
agcatcaacaatggcggtattgagtgtctgcgtttcctcaatgaaatcatctcagatttt
gactctctcctggacaatcccaagttccgggtgatcaccaagatcaaaaccattggcagc
acgtatatggcggcttcaggagtcacccctgatgtcaacaccaatggctttgccagctcc
aacaaggaggacaagtctgagagagaacgctggcagcacctggctgacctggccgacttt
gcgctggccatgaaggatacgctcaccaacatcaacaaccagtccttcaataacttcatg
ctgcgcataggcatgaacaaaggcggggttctggctggggtcatcggagcccggaaacca
cactacgacatctggggcaatacggtcaatgtagccagcaggatggagtccacgggggtc
atgggcaacatccaggtggtagaagaaacccaagtcatcctccgagagtacggcttccgc
tttgtgaggcggggccccatctttgtgaaggggaagggggagctgctgaccttcttcttg
aaggggcgggacaagccagccaccttccccaacggcccctctgtcacactgccccaccag
gtggtagacaactcctga

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