KEGG PATHWAY: rn00626

KEGG

PATHWAY: rn00626

Entry

rn00626 Pathway

Name

Naphthalene degradation

Class

Metabolism; Xenobiotics biodegradation and metabolism

Pathway map

Naphthalene degradation

Module

Naphthalene degradation, naphthalene => salicylate [PATH:rn00626]

Salicylate degradation, salicylate => gentisate [PATH:rn00626]

Other DBs

UMBBD:

naph nphs 1mna npa 2mna 2mna2

Reaction

salicylate,NADH:oxygen oxidoreductase (1-hydroxylating, decarboxylating)

salicylaldehyde:NAD+ oxidoreductase

naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase

naphthalene-1,2-diol:oxygen oxidoreductase

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate hydro-lyase

2-hydroxy-2H-chromene-2-carboxylate---(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate isomerase

naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase

salicylate,NADH:oxygen oxidoreductase (1-hydroxylating,decarboxylating)

1-hydroxymethylnaphthalene:NAD+ oxidoreductase

(2-naphthyl)methanol:NAD+ oxidoreductase

naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase

salicylate,NADH:oxygen oxidoreductase (1-hydroxylating,decarboxylating)

naphthalene,NADH:oxygen oxidoreductase (1,2-hydroxylating)

salicylate,NADH:oxygen oxidoreductase (1-hydroxylating,decarboxylating)

naphthalene disulfonate 1,2-dioxygenase

naphthalene disulfonate 1,2-dioxygenase

naphthalene disulfonate 1,2-dioxygenase

naphthalene disulfonate 1,2-dioxygenase

salicylate,NADH:oxygen oxidoreductase (5-hydroxylating)

salicylate,NADPH:oxygen oxidoreductase (5-hydroxylating)

Compound

Catechol

Succinyl-CoA

2,5-Dihydroxybenzoate

Salicylate

Naphthalene

(2-Naphthyl)methanol

2,3-Dihydroxytoluene

Naphthalene-1,2-diol

1-Hydroxy-2-naphthoate

cis-1,2-Dihydronaphthalene-1,2-diol

Salicylaldehyde

trans-o-Hydroxybenzylidenepyruvate

2-Hydroxychromene-2-carboxylate

4-Methylcatechol

1-Methylnaphthalene

cis-1,2-Dihydroxy-1,2-dihydro-8-methylnaphthalene

1,2-Dihydroxy-8-methylnaphthalene

2-Hydroxy-8-methylchromene-2-carboxylate

2-Hydroxy-3-methylbenzalpyruvate

3-Methylsalicylaldehyde

3-Methylsalicylate

1-Hydroxymethylnaphthalene

1-Naphthaldehyde

1-Naphthoic acid

cis-1,2-Dihydroxy-1,2-dihydro-8-carboxynaphthalene

1,2-Dihydroxy-8-carboxynaphthalene

2-Carboxy-2-hydroxy-8-carboxychromene

2-Hydroxy-3-carboxybenzalpyruvate

3-Formylsalicylic acid

2-Hydroxyisophthalic acid

2-Methylnaphthalene

2-Naphthaldehyde

4-Formylsalicylic acid

2-Naphthoic acid

cis-1,2-Dihydroxy-1,2-dihydro-7-methylnaphthalene

4-Methylsalicylate

cis-1,2-Dihydroxy-1,2-dihydro-7-hydroxymethylnaphthalene

1,2-Dihydroxy-7-hydroxymethylnaphthalene

2-Hydroxy-7-hydroxymethylchromene-2-carboxylate

2-Hydroxy-4-hydroxymethylbenzalpyruvate

4-Hydroxymethylsalicylaldehyde

4-Hydroxymethylsalicylate

4-Hydroxymethylcatechol

5,6,7,8-Tetrahydro-2-naphthoic acid

cis-2-Carboxycyclohexyl-acetic acid

Decahydro-2-naphthoic acid

Tetralin

2-Naphtylmethylsuccinic acid

Naphthyl-2-methyl-succinyl-CoA

Naphthyl-2-methylene-succinyl-CoA

Naphthyl-2-hydroxymethyl-succinyl CoA

Naphthyl-2-oxomethyl-succinyl-CoA

2-Naphthoyl-CoA

1,6-Naphthalenedisulfonic acid

2,6-Naphthalenedisulfonic acid

1,2-Dihydroxynaphthalene-6-sulfonate

(Z)-4-(2-Hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate

5-Sulfosalicylate

1-Naphthalenesulfonic acid

2-Naphthalenesulfonic acid

Reference

Authors

Kim SJ, Kweon O, Freeman JP, Jones RC, Adjei MD, Jhoo JW, Edmondson RD, Cerniglia CE.

Title

Molecular cloning and expression of genes encoding a novel dioxygenase involved in low- and high-molecular-weight polycyclic aromatic hydrocarbon degradation in Mycobacterium vanbaalenii PYR-1.

Journal

Appl Environ Microbiol 72:1045-54 (2006)
DOI:10.1128/AEM.72.2.1045-1054.2006

Reference

Authors

Denome SA, Stanley DC, Olson ES, Young KD

Title

Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway.

Journal

J Bacteriol 175:6890-901 (1993)
DOI:10.1128/JB.175.21.6890-6901.1993

Reference

Authors

Eaton RW, Chapman PJ

Title

Bacterial metabolism of naphthalene: construction and use of recombinant bacteria to study ring cleavage of 1,2-dihydroxynaphthalene and subsequent reactions.

Journal

J Bacteriol 174:7542-54 (1992)
DOI:10.1128/JB.174.23.7542-7554.1992

Reference

Authors

Morawski B, Eaton RW, Rossiter JT, Guoping S, Griengl H, Ribbons DW

Title

2-Naphthoate catabolic pathway in Burkholderia strain JT 1500.

Journal

J Bacteriol 179:115-21 (1997)
DOI:10.1128/JB.179.1.115-121.1997

Reference

Authors

Safinowski M, Meckenstock RU

Title

Enzymatic reactions in anaerobic 2-methylnaphthalene degradation by the sulphate-reducing enrichment culture N 47.

Journal

FEMS Microbiol Lett 240:99-104 (2004)
DOI:10.1016/j.femsle.2004.09.014

Reference

Authors

Annweiler E, Materna A, Safinowski M, Kappler A, Richnow HH, Michaelis W, Meckenstock RU

Title

Anaerobic degradation of 2-methylnaphthalene by a sulfate-reducing enrichment culture.

Journal

Appl Environ Microbiol 66:5329-33 (2000)
DOI:10.1128/AEM.66.12.5329-5333.2000

Reference

Authors

Annweiler E, Michaelis W, Meckenstock RU

Title

Identical ring cleavage products during anaerobic degradation of naphthalene, 2-methylnaphthalene, and tetralin indicate a new metabolic pathway.

Journal

Appl Environ Microbiol 68:852-8 (2002)
DOI:10.1128/AEM.68.2.852-858.2002

Reference

Authors

Aitken CM, Jones DM, Larter SR

Title

Anaerobic hydrocarbon biodegradation in deep subsurface oil reservoirs.

Journal

Nature 431:291-4 (2004)
DOI:10.1038/nature02922

Reference

Authors

Selesi D, Jehmlich N, von Bergen M, Schmidt F, Rattei T, Tischler P, Lueders T, Meckenstock RU

Title

Combined genomic and proteomic approaches identify gene clusters involved in anaerobic 2-methylnaphthalene degradation in the sulfate-reducing enrichment culture N47.

Journal

J Bacteriol 192:295-306 (2010)
DOI:10.1128/JB.00874-09

Related
pathway

Tyrosine metabolism

Benzoate degradation

Xylene degradation

KO pathway

LinkDB

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