KEGG   REACTION: R03472
Entry
R03472                      Reaction                               

Name
5-amino-1-(5-phospho-D-ribosyl)imidazole formate-lyase (decarboxylating, 4-amino-2-methyl-5-phosphomethylpyrimidine-forming)
Definition
Aminoimidazole ribotide + S-Adenosyl-L-methionine <=> 4-Amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-Deoxyadenosine + L-Methionine + Formate + CO
Equation
Reaction class
RC00021  C00019_C00073
RC03251  C03373_C04556
RC03252  C00058_C03373
Enzyme
Pathway
rn00730  Thiamine metabolism
rn01100  Metabolic pathways
rn01240  Biosynthesis of cofactors
Module
M00127  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/tyrosine) => TMP/TPP
M00895  Thiamine biosynthesis, prokaryotes, AIR (+ DXP/glycine) => TMP/TPP
M00896  Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP
M00897  Thiamine biosynthesis, plants, AIR (+ NAD+) => TMP/thiamine/TPP
Orthology
K03147  phosphomethylpyrimidine synthase [EC:4.1.99.17]
Other DBs
RHEA: 24843
LinkDB

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