KEGG   REACTION: R08264
Entry
R08264                      Reaction                               

Definition
Codeine + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Norcodeine + Formaldehyde + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
CYP3A4:N-demethylation
Reaction class
RC01198  C06174_C16576
RC02299  C00067_C06174
Enzyme
1.14.13.-
Pathway
rn00982  Drug metabolism - cytochrome P450
Orthology
K17689  cytochrome P450 family 3 subfamily A polypeptide 4 [EC:1.14.13.32 1.14.14.55 1.14.14.56 1.14.14.57 1.14.14.73 1.14.13.-]
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