KEGG   REACTION: R09421
Entry
R09421                      Reaction                               
Definition
4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+
Equation
C16453 + C00007 + C00005 + C00080 <=> C19563 + C00001 + C00006
Comment
CYP2A6, CYP2A13, CYP2D6, CYP2E1
Reaction class
RC00001  C00005_C00006
RC02530  C16453_C19563
Enzyme
1.14.14.1       1.14.14.-
Pathway
rn00980  Metabolism of xenobiotics by cytochrome P450
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.1
     R09421  4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+
    1.14.14.-
     R09421  4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone + Oxygen + NADPH + H+ <=> 4-[(Hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone + H2O + NADP+
Orthology
K07415  cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-]
K17683  cytochrome P450 family 2 subfamily A6 [EC:1.14.14.-]
K17685  cytochrome P450 family 2 subfamily A13 [EC:1.14.14.1]
K17712  cytochrome P450 family 2 subfamily D6 [EC:1.14.14.1]
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