KEGG   REACTION: R10027
Entry
R10027                      Reaction                               
Name
L-isoleucine,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (N-hydroxylating)
Definition
L-Isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
Comment
the first step of three-step reaction (see R09403, R10027+R10028+R10029)
Reaction class
RC00001  C00005_C00006
RC00365  C00407_C20310
Enzyme
Pathway
rn00460  Cyanoamino acid metabolism
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.38
     R10027  L-Isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O
    1.14.14.39
     R10027  L-Isoleucine + Oxygen + [Reduced NADPH---hemoprotein reductase] <=> N-Hydroxy-L-isoleucine + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K13401  valine N-monooxygenase [EC:1.14.14.38]
K14984  isoleucine N-monooxygenase [EC:1.14.14.39]
Other DBs
RHEA: 30482
LinkDB

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