KEGG   Rattus norvegicus (rat): 114846Help
Entry
114846            CDS       T01003                                 

Gene name
Gsto1, SPG-R
Definition
(RefSeq) glutathione S-transferase omega 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00480  Glutathione metabolism
rno00980  Metabolism of xenobiotics by cytochrome P450
rno00982  Drug metabolism - cytochrome P450
rno00983  Drug metabolism - other enzymes
rno01524  Platinum drug resistance
rno05200  Pathways in cancer
rno05204  Chemical carcinogenesis
rno05225  Hepatocellular carcinoma
rno05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    114846 (Gsto1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    114846 (Gsto1)
   00982 Drug metabolism - cytochrome P450
    114846 (Gsto1)
   00983 Drug metabolism - other enzymes
    114846 (Gsto1)
 09160 Human Diseases
  09161 Cancers: Overview
   05200 Pathways in cancer
    114846 (Gsto1)
   05204 Chemical carcinogenesis
    114846 (Gsto1)
  09162 Cancers: Specific types
   05225 Hepatocellular carcinoma
    114846 (Gsto1)
  09166 Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    114846 (Gsto1)
  09176 Drug resistance: Antineoplastic
   01524 Platinum drug resistance
    114846 (Gsto1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:rno02000]
    114846 (Gsto1)
Enzymes [BR:rno01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     114846 (Gsto1)
Transporters [BR:rno02000]
 Other Transporters
  Pores ion channels [TC:1]
   114846 (Gsto1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C GST_C_2 GST_C_3 Glutaredoxin GST_C_5
Motif
Other DBs
NCBI-GeneID: 114846
NCBI-ProteinID: NP_001007603
RGD: 70952
Ensembl: ENSRNOG00000028746
Vega: OTTRNOG00000000845
UniProt: Q6AXR6
LinkDB All DBs
Position
1q54
AA seq 241 aa AA seqDB search
MSGASARSLGKGSAPPGPVPEGQIRVYSMRFCPFAQRTLMVLKAKGIRHEIININLKNKP
EWFFEKNPFGLVPVLENTQGHLITESVITCEYLDEAYPEKKLFPDDPYEKACQKMTFELF
SKVPSLVTSFIRAKRKEDHPGIKEELKKEFSKLEEAMAKKRTAFFGGNSLSMIDYLIWPW
FQRLEALELNECIDHTPKLKLWMATMQEDPVASSHFIDAKTYRDYLSLYLQDSPEACDYG
L
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtccggggcgtccgccaggagcctggggaagggaagcgcgccccctggcccggtcccg
gagggccagatccgagtctacagcatgaggttctgtccctttgctcagaggacgctgatg
gtcctgaaggccaagggaatccggcatgaaatcatcaacatcaacctgaagaataagccc
gagtggttctttgagaagaatccctttgggctggtgccggttctggagaacactcagggt
cacttgatcactgaatctgtcatcacttgcgagtacctggatgaagcatacccggagaag
aagttattcccagatgacccgtacgagaaagcttgccagaagatgacctttgagttattc
tcaaaggtgccgtctctggttacgagttttattagggcgaagagaaaggaagaccatccg
ggcataaaggaagaactgaagaaagagttcagcaagctagaagaggctatggctaaaaag
aggacagccttcttcggtgggaattcgctctcaatgatcgattatcttatttggccgtgg
tttcagcgactggaagcactggagctcaatgagtgtatagaccacaccccaaaactcaag
ctctggatggcaaccatgcaggaagaccccgtggcatcatcccacttcattgatgccaag
acctaccgtgattacttaagtctctacctacaggacagccccgaggcctgtgattatggg
ctctga

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