KEGG   Rattus norvegicus (rat): 24379Help
Entry
24379             CDS       T01003                                 

Gene name
Gad1, Gad67
Definition
(RefSeq) glutamate decarboxylase 1
  KO
K01580  glutamate decarboxylase [EC:4.1.1.15]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00250  Alanine, aspartate and glutamate metabolism
rno00410  beta-Alanine metabolism
rno00430  Taurine and hypotaurine metabolism
rno00650  Butanoate metabolism
rno01100  Metabolic pathways
rno04727  GABAergic synapse
rno04940  Type I diabetes mellitus
Module
rno_M00027  GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:rno00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    24379 (Gad1)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    24379 (Gad1)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    24379 (Gad1)
   00430 Taurine and hypotaurine metabolism
    24379 (Gad1)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    24379 (Gad1)
 Human Diseases
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    24379 (Gad1)
Enzymes [BR:rno01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.15  glutamate decarboxylase
     24379 (Gad1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pyridoxal_deC Aminotran_5 Beta_elim_lyase DegT_DnrJ_EryC1 SepSecS OKR_DC_1
Motif
Other DBs
NCBI-GeneID: 24379
NCBI-ProteinID: NP_058703
RGD: 2652
Ensembl: ENSRNOG00000000007
UniProt: P18088 C9E895
LinkDB All DBs
Position
3q22
AA seq 593 aa AA seqDB search
MASSTPSPATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKS
RLVSAFRERQASKNLLSCENSDPGARFRRTETDFSNLFAQDLLPAKNGEEQTVQFLLEVV
DILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVR
TGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIIGWSN
KDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAAL
GFGTDNVILIKCNERGKIIPADLEAKILDAKQKGFVPLYVNATAGTTVYGAFDPIQEIAD
ICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEK
GILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQIN
KCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPK
IKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
NT seq 1782 nt NT seq  +upstreamnt  +downstreamnt
atggcatcttccacgccttcgcctgcaacctcctcgaacgcgggagcggatcctaatact
accaacctgcgtcctacaacatatgatacttggtgtggcgtagcccatggatgcaccaga
aaactgggcctgaagatctgtggtttcttgcaaaggaccaatagcctggaagagaagagt
cgtcttgtgagcgccttcagggagaggcaggcctccaagaacctgctttcctgtgaaaac
agtgaccctggtgcccgcttccggcgcacagagacggacttctccaacctgtttgctcaa
gatctgcttccagctaagaacggggaggagcaaactgtgcagttcttactggaggtggtt
gacatactcctcaactatgtccgcaagacgtttgatcgctccaccaaggttttggacttc
caccacccacaccagttgctggaaggcatggaaggttttaatttggagctgtctgaccac
cccgagtctctggagcagatcctggttgactgtagagacaccctaaagtacggggttcgc
acaggtcaccctcggtttttcaaccagctctctactggtttggatatcattggtttagct
ggcgaatggctgacatcaactgccaataccaatatgttcacatatgaaattgcacccgtg
tttgttcttatggaacagatcacacttaagaagatgcgagagatcattggatggtcaaat
aaagatggtgatgggatattttctcctgggggagccatatccaacatgtacagcatcatg
gcggctcggtacaagtactttccagaagtgaaaacaaaaggcatggcggctgtgcccaaa
ctggtcctcttcacctcagaacacagtcactattccataaagaaggctggggctgcgctt
ggctttggaactgacaatgtgatcctgataaagtgcaatgaaagggggaagataattcca
gctgatttagaggcaaaaattcttgatgccaaacaaaagggatttgttcccctttatgtc
aatgcaaccgcaggcacgactgtttatggagcgtttgatccgatccaggagattgcagac
atatgtgagaaatacaacctttggctgcatgtggatgctgcctggggtggtgggctgctc
atgtcccggaagcatcgccacaaactcagcggcatagaaagggccaattcagtcacctgg
aaccctcacaagatgatgggtgtgctgctccagtgttctgccatcctggtcaaggaaaag
ggtatactccaaggatgcaaccagatgtgtgcaggctacctcttccagccagacaagcag
tatgacgtctcctacgatacaggggacaaggcgattcagtgtggccgccatgtggacatc
ttcaagttctggctgatgtggaaagcaaagggcactgtgggatttgaaaatcagatcaac
aaatgcctggagctggctgaatacctctatgccaagattaaaaacagagaagagtttgag
atggttttcaatggtgagcctgagcacacaaatgtctgtttctggtacataccacaaagc
ctccgaggggttccagacagccctgagcgacgagaaaaactacacagggtggctcccaag
atcaaagccctgatgatggagtcaggaacaaccatggttggttaccagcctcaaggggac
aaggccaacttcttccggatggtcatctccaacccagccgccacccagtctgacatcgat
ttcctcatcgaggaaatagagaggttgggtcaagatctgtaa

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