KEGG   Rattus norvegicus (rat): 25204Help
Entry
25204             CDS       T01003                                 

Gene name
Pcsk1, BDP, PC1, PC3
Definition
(RefSeq) proprotein convertase subtilisin/kexin type 1
  KO
K01359  proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
Organism
rno  Rattus norvegicus (rat)
Brite
KEGG Orthology (KO) [BR:rno00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases [BR:rno01002]
    25204 (Pcsk1)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:rno03110]
    25204 (Pcsk1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.93  proprotein convertase 1
     25204 (Pcsk1)
Peptidases [BR:rno01002]
 Serine Peptidases
  Family S8: subtilisin family
   25204 (Pcsk1)
Chaperones and folding catalysts [BR:rno03110]
 Intramolecular chaperones
  Subtilisin family
   25204 (Pcsk1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Peptidase_S8 P_proprotein S8_pro-domain Proho_convert OmpA_membrane Peptidase_S8_N
Motif
Other DBs
NCBI-GeneID: 25204
NCBI-ProteinID: NP_058787
RGD: 3272
Ensembl: ENSRNOG00000011107
UniProt: P28840
LinkDB All DBs
Position
2q23
AA seq 752 aa AA seqDB search
MKQRGWTLQCTAFTLFCVWCALNSVKAKRQFVNEWAAEIHGGPEAASAIAEELGYDLLGQ
IGSLENHYLFKHKNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERRKRSVPRDSALNL
FNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYAN
YDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRM
LDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKG
SIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDY
TDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPL
ANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECIIKDNNFEPRALK
ANGEVIVEIPTRACEGQENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERE
RDTSPNGFKNWDFMSVHTWGENPVGTWTLKVTDMSGRMQNEGRIVNWKLILHGTSSQPEH
MKQPRVYTSYNTVQNDRRGVEKMVNVVEEKPTQNSLNGNLLVPKNSSSSSVEDRRDEQVQ
GAPSKAMLRLLQSAFSKNTPSKQSSKIPSAKLSVPYEGLYEALEKLNKPSQLEDSEDSLY
SDYVDVFYNTKPYKHRDDRLLQALMDILNEKN
NT seq 2259 nt NT seq  +upstreamnt  +downstreamnt
atgaagcaaagaggttggactctgcagtgtactgctttcaccctcttttgcgtttggtgt
gcactgaacagtgtaaaagcgaagaggcagtttgtcaatgaatgggcggcggagatacat
ggagggccagaagctgcttctgccattgccgaagagctgggctatgacctcttgggtcag
attggatcacttgaaaatcactatttattcaaacacaaaaatcatcctcgaagatcccga
agaagtgctcttcatatcactaagaggttatctgatgatgatcgtgtgatatgggcggaa
caacaatatgaaaaagagagaagaaaacgttcagttccaagagactcagcattgaatctc
ttcaatgatccaatgtggaatcagcagtggtacttgcaagacaccagaatgactgcatct
ctgcccaagctggacttgcatgtaatacctgtttggcaaaagggtattactggcaaagga
gttgttattactgtactggacgatggcttggagtggaatcacacagatatttatgccaat
tatgacccagaggctagctatgattttaatgataatgatcatgatccatttccccgatat
gatcccacaaatgaaaacaaacatggaacaagatgtgcaggagaaattgccatgcaagca
aataatcacaaatgtggagttggagttgcatataattccaaagttggaggcataagaatg
ctggatggcattgtaactgatgccattgaggctagttcaattggattcaaccctggccat
gtggatatttacagtgcaagctggggccctaatgatgatggaaaaactgtggaggggcct
ggcagactagcccagaaggcatttgaatacggtgtcaaacaggggagacaaggaaaaggc
tccatttttgtctgggcttcagggaatgggggtcgtcaaggagataactgtgactgtgat
ggctacacagacagcatttacaccatctctatcagcagtgcctcccagcagggcctgtca
ccctggtatgcagagaagtgttcctccacactggccacctcctacagcagtggtgattac
acagaccaacgaataactagtgcggacctgcacaatgactgcacagagacccacacaggc
acctcagcttctgcacctctggctgctggcatctttgctctagccttggaagcaaaccca
aatctcacctggcgagatatgcagcatctggttgtctggacctctgagtatgacccattg
gccaataacccaggttggaaaaagaatggagcgggcttgatggtgaacagccgatttgga
tttggcttgctaaatgccaaagctctggtggatttggctgatcctagaacttggagaaac
gtgcctgagaagaaagaatgtatcataaaagacaacaactttgagcctagagccctgaaa
gctaatggagaagtgattgttgaaatccctacaagagcttgtgaaggacaagaaaatgct
atcaattccctggaacatgtgcaatttgaagcaacaatcgaatattctcgtagaggagac
cttcatgtcacacttacctctgctgctggaaccagcaccgtactgttggctgaaagggaa
agggatacatcccccaatggctttaagaattgggacttcatgtctgttcatacatgggga
gagaatcctgtaggcacctggacattgaaagttacagacatgtctggaagaatgcaaaat
gaaggaaggattgtgaactggaagttgattttgcatggcacatcttctcagccagaacac
atgaagcagcctcgtgtatacacgtcctacaatactgtccagaatgacaggagaggagtg
gaaaagatggtgaatgttgtggaggagaagcccacacaaaacagcctgaatggcaatctc
ctggtacccaaaaactccagcagcagcagtgtggaagacagaagagatgagcaggtacaa
ggagctccttcaaaggccatgctacggctcctacaaagtgctttcagcaagaacacacct
tcaaagcaatcatcaaagattccaagtgctaagctcagtgtcccttatgagggtctctat
gaagccctggaaaagctcaacaagccctcccagcttgaagactctgaagacagtctgtat
agcgactatgttgatgttttctataacacaaaaccttataagcatagagatgacaggctg
ctgcaagcactcatggacattctgaatgagaagaattaa

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