Rattus norvegicus (rat): 25289 Help Entry 25289             CDS       T01003                                  Gene name Adcy6, AC6, ACVI, ADCYB Definition (RefSeq) adenylate cyclase 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04742   Taste transduction rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04924   Renin secretion rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04961   Endocrine and other factor-regulated calcium reabsorption rno04962   Vasopressin-regulated water reabsorption rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     25289 (Adcy6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     25289 (Adcy6)    04371 Apelin signaling pathway     25289 (Adcy6)    04072 Phospholipase D signaling pathway     25289 (Adcy6)    04024 cAMP signaling pathway     25289 (Adcy6)    04022 cGMP-PKG signaling pathway     25289 (Adcy6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     25289 (Adcy6)   09144 Cellular community - eukaryotes    04540 Gap junction     25289 (Adcy6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     25289 (Adcy6)    04062 Chemokine signaling pathway     25289 (Adcy6)   09152 Endocrine system    04911 Insulin secretion     25289 (Adcy6)    04923 Regulation of lipolysis in adipocytes     25289 (Adcy6)    04912 GnRH signaling pathway     25289 (Adcy6)    04913 Ovarian steroidogenesis     25289 (Adcy6)    04915 Estrogen signaling pathway     25289 (Adcy6)    04914 Progesterone-mediated oocyte maturation     25289 (Adcy6)    04921 Oxytocin signaling pathway     25289 (Adcy6)    04926 Relaxin signaling pathway     25289 (Adcy6)    04935 Growth hormone synthesis, secretion and action     25289 (Adcy6)    04918 Thyroid hormone synthesis     25289 (Adcy6)    04928 Parathyroid hormone synthesis, secretion and action     25289 (Adcy6)    04916 Melanogenesis     25289 (Adcy6)    04924 Renin secretion     25289 (Adcy6)    04925 Aldosterone synthesis and secretion     25289 (Adcy6)    04927 Cortisol synthesis and secretion     25289 (Adcy6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     25289 (Adcy6)    04270 Vascular smooth muscle contraction     25289 (Adcy6)   09154 Digestive system    04970 Salivary secretion     25289 (Adcy6)    04971 Gastric acid secretion     25289 (Adcy6)    04972 Pancreatic secretion     25289 (Adcy6)    04976 Bile secretion     25289 (Adcy6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     25289 (Adcy6)    04961 Endocrine and other factor-regulated calcium reabsorption     25289 (Adcy6)   09156 Nervous system    04724 Glutamatergic synapse     25289 (Adcy6)    04727 GABAergic synapse     25289 (Adcy6)    04725 Cholinergic synapse     25289 (Adcy6)    04723 Retrograde endocannabinoid signaling     25289 (Adcy6)   09157 Sensory system    04742 Taste transduction     25289 (Adcy6)    04750 Inflammatory mediator regulation of TRP channels     25289 (Adcy6)   09149 Aging    04211 Longevity regulating pathway     25289 (Adcy6)    04213 Longevity regulating pathway - multiple species     25289 (Adcy6)   09159 Environmental adaptation    04713 Circadian entrainment     25289 (Adcy6)    04714 Thermogenesis     25289 (Adcy6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     25289 (Adcy6)   09165 Substance dependence    05032 Morphine addiction     25289 (Adcy6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     25289 (Adcy6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     25289 (Adcy6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     25289 (Adcy6)    05163 Human cytomegalovirus infection     25289 (Adcy6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     25289 (Adcy6) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      25289 (Adcy6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  25289 NCBI-ProteinID:  NP_036953 RGD:  2035 Ensembl:  ENSRNOG00000054757 UniProt:  Q03343 LinkDB All DBs Position 7q36 AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRQATRARGFCAPRYMSCLKNVEPPSPTPAART RCPWQDEAFIRRAGPGRGVKLGLRSVALGFDDTEVTTPMGTAEVAPDTSPRSGPSCWHRL AQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLMAVLLTFHAAPALPQPAYVA LLTCASVLFVVLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAANPRSPSAGLWCP VFFVYITYTLLPIRMRAAVLSGLGLSTLHLILAWHLNNGDPFLWKQLGANVVLFLCTNAI GVCTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNGYL KEQCIETFLILGASQKRKEEKAMLVKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFRQM GIDDSSKENRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQFLVFPHSALILGIYAGIFLLLLVTVLICAVCSCGS FFPNALQRLSRSIVRSRVHSTAVGVFSVLLVFISAIANMFTCSHTPLRTCAARMLNLTPS DVTACHLRQINYSLGLEAPLCEGTAPTCSFPEYFVGSVLLSLLASSVFLHISSIGKLVMT FVLGFIYLLLLLLGPPATIFDNYDLLLSVHGLASSNETFDGLDCPAVGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagcggcctcctggttcccaaagtggatgaacggaaaacagcctggggc gaacgcaatggacagaagcgcccacgccaggcgacccgagcccgtggcttctgcgcgccc cgctacatgagctgcctcaagaatgtggagccacccagccccactcctgcagctcgcact cggtgcccctggcaggatgaagccttcatcaggagggctggcccgggaaggggtgtgaag ctggggctgcggtcagtggccttgggttttgatgacactgaggtgaccacaccgatgggg acagctgaagtggcacccgacacatcgcctcgaagcggtccgtcctgctggcaccggcta gcgcaggtgttccagtctaagcagttccgctccgccaagctggagcgtctgtaccagcgg tacttcttccagatgaaccagagcagcctcacgctgctcatggcggtgcttgtgctcctc atggctgtactgttgaccttccacgccgcgcctgccctgcctcagcctgcttatgtggcc ctgctgacctgtgcctccgtcctttttgtggtactcatggtagtgtgtaaccgacatagc ttccgccaggactccatgtgggtagtgagctatgtggttctgggcatcctagcagccgtg caagtcgggggtgccctggcagccaacccacgcagcccctcagcaggcctttggtgcccc gtgttcttcgtctacatcacctacacacttcttcccattcgtatgcgagcggccgtgctc agtggcctgggtctttccaccctgcatttgattttggcctggcatctcaacaatggtgac cccttcctttggaagcagctcggtgctaacgtggtgctcttcctgtgcaccaatgccatc ggtgtctgcacgcactaccccgctgaagtgtctcagcgccaagcctttcaggagacccgt ggttacatccaggcccggctgcacttgcagcatgagaatcgacagcaggaacggctgctg ctgtcggtgttgccccagcatgttgccatggaaatgaaagaggatatcaacacaaaaaag gaagacatgatgttccacaagatttacatccagaagcatgacaatgtcagcatcctgttt gccgacatcgagggcttcaccagcctggcctcccagtgcactgcccaggaactggtcatg accttgaatgagctctttgcccggttcgacaagctggctgcggagaatcactgtctgagg atcaagatcttaggagactgttactactgtgtgtcggggctgccggaggcccgggcagac catgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctggtgcgt gaggtaacgggtgtaaatgtgaacatgcgcgtgggcatccacagcgggcgtgtacactgc ggtgtccttggtctgcggaaatggcagtttgatgtctggtccaacgatgtgaccctggcc aaccacatggaggcggggggccgggccggccgcatccacatcactcgggccacactgcag tacctgaacggggactatgaggtggagccaggccgtggcggtgagcgcaacggctacctc aaggagcagtgcattgagaccttcctcatactaggagccagccagaaacggaaagaggag aaggccatgctggtcaagctgcagcggacgcgggccaactccatggaaggactgatgccc cgctgggttcctgaccgtgccttctcccggaccaaggactctaaggcattccgacagatg ggcatcgatgactctagcaaagagaaccggggtgcccaagatgctctgaaccctgaggat gaggtggacgagtttctgggccgagccatcgatgcccgaagcatcgaccagctgcgtaag gaccatgtgcgccggttcctgctcaccttccagagggaggatctcgagaagaagtattca cggaaagtagaccctcgtttcggagcctacgtcgcctgtgccctcctggttttctgcttc atctgtttcatccagttcctcgtattcccacactccgccctgatactcgggatttatgcc gggatcttccttttgctgctggtcaccgtgctcatctgtgctgtgtgctcctgtgggtct ttcttccccaacgccctgcagcgcctgtcccgcagtatcgtccgctcacgggtgcacagc acggctgttggagtcttctcggttctgcttgtgttcatctctgccattgccaacatgttc acctgcagtcacaccccactgaggacctgtgcggcccggatgctgaacttaacaccgtcc gatgtcaccgcctgtcacctacgacagatcaattactctctgggactggaagctcccctg tgtgagggcacagcacccacctgcagtttccctgagtactttgtcgggagtgtgctgttg agtctcttggccagctccgtcttcctccacatcagcagcattggcaagctagttatgacc tttgtcttggggttcatctacttgcttctgcttttgctgggtcccccagccaccatcttt gacaactatgatctactgcttagcgtccatggcttggcttcctccaatgagaccttcgat gggctggactgcccagccgtagggagggtagcgctcaaatacatgacccctgtgattctc ctcgtgttcgccctggcactgtatctacacgcacaacaggtggaatctaccgcccgcctg gacttcctgtggaaactgcaggccacaggggagaaggaggagatggaggagttgcaggcc tacaaccggcggctgctgcataacatccttcccaaggacgtggctgcccacttcctggcc cgggagcgccgcaacgacgagctgtactaccaatcctgcgagtgcgtggctgtcatgttt gcctccatcgccaacttctctgagttctatgtggaactggaggcgaacaatgagggcgtg gagtgcctgcgactgctcaatgagatcatcgcggactttgatgagatcatcagtgaggag aggttccggcagctggagaagatcaagaccatcggtagcacttacatggccgcctccggg ctaaatgccagcacctatgaccaggtcggccgctcgcacatcaccgccctggcagactac gccatgcggcttatggagcaaatgaaacacatcaacgaacactctttcaacaacttccag atgaagatcgggttgaacatgggtccggttgtagcaggtgtcattggggcccggaagcca cagtatgacatctggggaaacacggtgaatgtttccagccgtatggacagcacaggagtt cctgaccgaatacaggtgaccacggatctctaccaggttctagctgccaagggctaccaa ctggagtgtcgaggggtggtcaaggtgaagggaaagggggagatgaccacctacttcctc aatgggggccccagcagttag

Rattus norvegicus (rat): 29241 Help Entry 29241             CDS       T01003                                  Gene name Adcy8, Ac8 Definition (RefSeq) adenylate cyclase 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04720   Long-term potentiation rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04742   Taste transduction rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     29241 (Adcy8)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     29241 (Adcy8)    04371 Apelin signaling pathway     29241 (Adcy8)    04020 Calcium signaling pathway     29241 (Adcy8)    04072 Phospholipase D signaling pathway     29241 (Adcy8)    04024 cAMP signaling pathway     29241 (Adcy8)    04022 cGMP-PKG signaling pathway     29241 (Adcy8)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     29241 (Adcy8)   09144 Cellular community - eukaryotes    04540 Gap junction     29241 (Adcy8)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     29241 (Adcy8)    04062 Chemokine signaling pathway     29241 (Adcy8)   09152 Endocrine system    04911 Insulin secretion     29241 (Adcy8)    04923 Regulation of lipolysis in adipocytes     29241 (Adcy8)    04912 GnRH signaling pathway     29241 (Adcy8)    04913 Ovarian steroidogenesis     29241 (Adcy8)    04915 Estrogen signaling pathway     29241 (Adcy8)    04914 Progesterone-mediated oocyte maturation     29241 (Adcy8)    04921 Oxytocin signaling pathway     29241 (Adcy8)    04926 Relaxin signaling pathway     29241 (Adcy8)    04935 Growth hormone synthesis, secretion and action     29241 (Adcy8)    04918 Thyroid hormone synthesis     29241 (Adcy8)    04928 Parathyroid hormone synthesis, secretion and action     29241 (Adcy8)    04916 Melanogenesis     29241 (Adcy8)    04925 Aldosterone synthesis and secretion     29241 (Adcy8)    04927 Cortisol synthesis and secretion     29241 (Adcy8)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     29241 (Adcy8)    04270 Vascular smooth muscle contraction     29241 (Adcy8)   09154 Digestive system    04970 Salivary secretion     29241 (Adcy8)    04971 Gastric acid secretion     29241 (Adcy8)    04972 Pancreatic secretion     29241 (Adcy8)    04976 Bile secretion     29241 (Adcy8)   09156 Nervous system    04724 Glutamatergic synapse     29241 (Adcy8)    04727 GABAergic synapse     29241 (Adcy8)    04725 Cholinergic synapse     29241 (Adcy8)    04720 Long-term potentiation     29241 (Adcy8)    04723 Retrograde endocannabinoid signaling     29241 (Adcy8)   09157 Sensory system    04742 Taste transduction     29241 (Adcy8)    04750 Inflammatory mediator regulation of TRP channels     29241 (Adcy8)   09149 Aging    04211 Longevity regulating pathway     29241 (Adcy8)    04213 Longevity regulating pathway - multiple species     29241 (Adcy8)   09159 Environmental adaptation    04713 Circadian entrainment     29241 (Adcy8)    04714 Thermogenesis     29241 (Adcy8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     29241 (Adcy8)   09165 Substance dependence    05032 Morphine addiction     29241 (Adcy8)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     29241 (Adcy8)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     29241 (Adcy8)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     29241 (Adcy8)    05163 Human cytomegalovirus infection     29241 (Adcy8)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     29241 (Adcy8) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      29241 (Adcy8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 TBK1_ULD Motif Other DBs NCBI-GeneID:  29241 NCBI-ProteinID:  NP_058838 RGD:  2036 Ensembl:  ENSRNOG00000004890 UniProt:  P40146 LinkDB All DBs Position 7q33 AA seq 1248 aa AA seqDB search MELSDVHCLSGSEELYTIHPTPPAADGGSGSRPQRLLWQTAVRHITEQRFIHGHRGGGGG GSRKASNPAGSGPNHHAPQLSSDSVLPLYSLGSGERAHNTGGTKVFPERSGSGSASGSGG GGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRKSEV VMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHTYLQ YSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTSLLQ VTLQVLIPRLAVFSINQVLAQVVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEARLRL ETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGF TNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCV EMGLSMIKTIRFVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESG GIPGRIHISKATLDCLSGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLSLPEDIVK ESVSCSDRRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSG PEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVL LFITAIQSLLPSSRLMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYL ARNVIIFASILINFLGAVINILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLA MVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLSYDNLNHSGEDFLGTKEASLL LMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKDLREHNENMLRNILPGHVARHF LEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLG EDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFN NFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQ GFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSL NRQRQKQLLNENSNSGIIKSHYNRRTLLTPSGPEPGAQAEGTDKSDLP NT seq 3747 nt NT seq  +upstreamnt  +downstreamnt atggaactctcggatgtgcactgccttagcggcagcgaggaactctataccattcacccg acgcccccggccgcggacggcgggagcggctctcggccgcagcggctgctgtggcagacg gcggtgcggcacatcaccgagcagcgcttcatccacggccaccgaggcggcggcggcggg ggctcccgcaaagcctcgaaccctgcgggcagcggaccaaaccaccacgcgccgcagctg tctagcgactcggtgctgcctctctattctctgggctccggagagcgagcgcacaacacc ggtggcaccaaagtctttccggaacgcagcgggagcggcagtgccagtggcagcgggggt gggggcgacttgggcttcctgcaccttgactgtgccccaagtaactcggatttcttcctc aatgggggatacagctaccgtggggtcattttcccaaccctacgcaactccttcaagtct cgggatctggagcgcctctatcaacgctatttcctgggccagaggcgcaaatcggaggta gtgatgaacgtgctggatgtactaaccaaactcacccttctagtccttcacttgagccta gcctcggctcccatggaccctctcaagggcatcctgctaggctttttcactggcatcgag gtggtgatctgcgccctcgtggtggtcaggaaggacaccacctcccacacttacctgcaa tacagcggcgtggtcacttgggtggctatgaccacccagattctggcagcaggcctgggc tatgggcttctgggcgacggcataggctacgtgctttttacactcttcgccacctacagc atgcttccgctgcctctcacctgggccatcttggccggcctgggcacatccttgctgcaa gtcacacttcaagtgctcatacccagactagcggtcttttccatcaaccaggtcctggcc caggtggtgctcttcatgtgcatgaatacagcaggcatcttcatcagttacctttcagac cgcgcccagcggcaggccttcctggagacccggaggtgtgtggaggccaggctccgcctg gagacagagaaccaaagacaggagcggcttgtgctctctgtgctccccaggtttgtcgtc ctagaaatgatcaatgacatgaccaatgtggaggacgagcacctgcagcatcagttccac cgcatctacatccatcgctacgagaacgtcagtattctttttgcagatgtcaaaggattt accaacctctctacgaccttgtctgctcaggagcttgtcaggatgctcaacgagctcttt gccagatttgatcggctggcccatgagcatcactgtcttcgcattaaaatcctgggggac tgctactactgtgtgtcaggactgcctgagccccgccaggaccatgctcattgctgtgtt gaaatgggcctcagcatgatcaaaactatcaggtttgtgaggtccagaacgaagcatgat gttgacatgcgaattggaatccattcaggctctgtgctgtgtggtgtgttgggcctgaga aaatggcagtttgatgtctggtcttgggatgtggacatcgcaaacaaacttgaatctgga ggaatccctgggagaattcacatttccaaagccacactggattgcctcagtggtgactat aatgtggaagagggccacggtaaggagaggaatgaattcttgaggaagcataatatagag acctatttgattaagcagcccgaggagagtttgctatccttgcctgaagatatagttaag gagtcggtgagctgctcggacaggagaaacagtggggcaacgttcacagaaggatcctgg agcccagaactgccattcgacaacatcgtgggcaaacagaatactctggctgccctaaca agaaattcaataaatctgcttccaaaccatctcgcacaagctttgcatgtccagtctggg cctgaggaaattaacaagagaatagagcataccatcgacttgcggagtggcgataagttg agaagagagcatatcaagccattctcactgatgtttaaagactccagcctggagcacaag tattctcaaatgcgggatgaagtattcaagtcaaacttggtctgtgcatttatcgttctt ctgtttatcactgcgattcaaagtttgcttccttcttcgaggctgatgcctatgaccatc cagttctccatcctgatcatgctgcactccgccctggtcctcatcaccacggcagaagac tataagtgtctgcctctcattctccgcaaaacctgttgttggattaacgagacctatttg gcccgcaacgtcatcatctttgcttccatcttgattaatttcctgggagccgtcataaat attctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttcaattcctca gctgtgtttacagatatctgctcctacccagagtactttgtcttcactggggtgttggcc atggtgacgtgtgcagtatttctccggcttaactctgtcctgaagctggctgtgctgctc attatgatcgccatctacgccctgctgacagagaccatctatgcaggtctctttctgagt tatgacaacctgaaccacagtggagaagattttctggggaccaaggaggcatcactgcta ctgatggccatgttccttcttgctgtattctaccatggacagcagctggagtacacagcc cgcctagatttcctgtggcgagtacaggccaaagaggagatcaacgagatgaaggacttg agggaacacaatgagaacatgcttcgcaatatcttacccggccacgtggcccgccacttc ctggagaaagacagagacaatgaggagctgtattctcaatcctatgatgccgttggggta atgtttgcctccattcctggatttgcagacttttactctcagacagaaatgaacaaccag ggagtggaatgtctgcgcttgctgaatgagatcattgctgactttgatgagttacttgga gaggaccgctttcaggacatagagaagattaagaccattggtagtacatacatggctgtc tcaggactgtcaccagagaaacagcaatgtgaagataaatggggacatttgtgtgccctg gctgacttctctcttgccctgactgaaagcatacaagagatcaacaagcattcgttcaac aattttgaactccgtattggcatcagccatggctcagtggtagcaggtgtaattggcgct aagaaaccacagtatgacatttggggtaaaactgtgaacttggcaagccgaatggacagc acaggagtgagtggccggatccaagttcctgaggagacctatctcatcctgaaggatcag ggctttgccttcgactaccggggagagatatatgtgaagggcatcagcgaacaagaaggg aaaatcaaaacatattttctcctgggacgagtccaacccaacccattcatcttaccccca agaagacttcctgggcagtactctctggctgcagttgtccttgggcttgtccagtctctc aacaggcaaaggcagaagcaactactcaatgagaacagcaactctggcatcatcaagagc cattacaaccggcggactttgctaacgccaagtgggccagagcctggagcacaggctgaa ggcactgacaaatccgatttgccataa

Rattus norvegicus (rat): 302950 Help Entry 302950            CDS       T01003                                  Gene name Adcy9 Definition (RefSeq) adenylate cyclase 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04961   Endocrine and other factor-regulated calcium reabsorption rno04962   Vasopressin-regulated water reabsorption rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     302950 (Adcy9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     302950 (Adcy9)    04371 Apelin signaling pathway     302950 (Adcy9)    04020 Calcium signaling pathway     302950 (Adcy9)    04072 Phospholipase D signaling pathway     302950 (Adcy9)    04024 cAMP signaling pathway     302950 (Adcy9)    04022 cGMP-PKG signaling pathway     302950 (Adcy9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     302950 (Adcy9)   09144 Cellular community - eukaryotes    04540 Gap junction     302950 (Adcy9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     302950 (Adcy9)    04062 Chemokine signaling pathway     302950 (Adcy9)   09152 Endocrine system    04911 Insulin secretion     302950 (Adcy9)    04923 Regulation of lipolysis in adipocytes     302950 (Adcy9)    04912 GnRH signaling pathway     302950 (Adcy9)    04913 Ovarian steroidogenesis     302950 (Adcy9)    04915 Estrogen signaling pathway     302950 (Adcy9)    04914 Progesterone-mediated oocyte maturation     302950 (Adcy9)    04921 Oxytocin signaling pathway     302950 (Adcy9)    04926 Relaxin signaling pathway     302950 (Adcy9)    04935 Growth hormone synthesis, secretion and action     302950 (Adcy9)    04918 Thyroid hormone synthesis     302950 (Adcy9)    04928 Parathyroid hormone synthesis, secretion and action     302950 (Adcy9)    04916 Melanogenesis     302950 (Adcy9)    04925 Aldosterone synthesis and secretion     302950 (Adcy9)    04927 Cortisol synthesis and secretion     302950 (Adcy9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     302950 (Adcy9)    04270 Vascular smooth muscle contraction     302950 (Adcy9)   09154 Digestive system    04970 Salivary secretion     302950 (Adcy9)    04971 Gastric acid secretion     302950 (Adcy9)    04972 Pancreatic secretion     302950 (Adcy9)    04976 Bile secretion     302950 (Adcy9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     302950 (Adcy9)    04961 Endocrine and other factor-regulated calcium reabsorption     302950 (Adcy9)   09156 Nervous system    04724 Glutamatergic synapse     302950 (Adcy9)    04727 GABAergic synapse     302950 (Adcy9)    04725 Cholinergic synapse     302950 (Adcy9)    04723 Retrograde endocannabinoid signaling     302950 (Adcy9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     302950 (Adcy9)   09149 Aging    04211 Longevity regulating pathway     302950 (Adcy9)    04213 Longevity regulating pathway - multiple species     302950 (Adcy9)   09159 Environmental adaptation    04713 Circadian entrainment     302950 (Adcy9)    04714 Thermogenesis     302950 (Adcy9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     302950 (Adcy9)   09165 Substance dependence    05032 Morphine addiction     302950 (Adcy9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     302950 (Adcy9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     302950 (Adcy9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     302950 (Adcy9)    05163 Human cytomegalovirus infection     302950 (Adcy9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     302950 (Adcy9) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      302950 (Adcy9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF512 zf-C2HC_2 DUF1053 Motif Other DBs NCBI-GeneID:  302950 NCBI-ProteinID:  XP_008765747 RGD:  1304747 Ensembl:  ENSRNOG00000049768 Vega:  OTTRNOG00000000982 LinkDB All DBs Position 10q12 AA seq 1373 aa AA seqDB search MASSPHQQLLHHHSTEVSCDSSGDSNSVRVKINPKQLSSNTHPKHCKYSISSSCSSSGDS GGLPRRVGGGGRLRRQKKLPQLFERASSRWWDPKFDSVNLEEACLERCFPQTQRRFRYAL FYVGFACLLWSIYFAVHMRSKVIVMVVPALCFLVVCVGFFLFTFTKLYARHYAWTSLALT LLVFALTLAAQFQVWTPLSGRVDSPNHTLTAKAADTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLFLGVVYSVLFETFGYHFRNEDCFPSPDPGALHWELLSRALLHVCIHAIGIHLFV MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKASIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIKAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGRVMERLGQSVVADQLKGLKTYLISGQRAKESHCSCAEALLSGFEVIDDSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQDEPKA STKVTSSWLLFLSVPLLAHPPKASGGPNSKTQNGLLSPPAEEKLTNSQTSLCEILQEKGR WAGVSLDQSALLPLRFKNIREKTDAHFVDVIKEDSLMKDYFFKPPISQFSLNFLDQELEQ SYRASYQEEVIKNSPVKTFASATFSSLLDVFLSTTVFLILSITCFLKYGATATPPPPAAL AVFGADLLLEVLSLIVSIRMVFFLEDVLTCTKRLLEWIAGWLPRHCIGAILVSLPALAVY SHITSEFETNINFTMLTGSAVLVAVVHYCNFCQLSSWMRSSLATLVGAGPLLLLYISLCQ DSSIVMSPLDTAQNFSASERSPCNSSVLQDGRRPASLIGKELILTFFLLLLLVWFLNREF EVSYRLHYHGDVEADLHRTKIQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVI FASIVNFSEFYEENYEGGKECYRVLNELIGDFDELLSKPDYNSIEKIKTIGATYMAASGL NTAQCQEGGHPQEHLRILFEFAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTT KLLYDIWGDTVNIASRMDTTGVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTY LYPKCTDNGVVPQHQLSISPDIRVQVDGSIGRSPTDEITNLVPSVQYLDKASLGSDDGAQ TKEATLSSKRPWREPVKAEERFRFGKAIEKEDCEDTGAEEANELTKLNVSKSV NT seq 4122 nt NT seq  +upstreamnt  +downstreamnt atggcttcctcaccccaccagcagctgctgcatcaccatagcaccgaggtgagctgcgac tcaagcggagacagcaacagcgtgagggtcaagatcaaccctaagcagctgtcctccaac acccacccgaagcactgcaagtacagcatctcctccagctgtagcagctcgggagactca gggggccttccccggcgggtgggcggcgggggtcgcctgcgaagacagaagaagctgccc cagctgttcgagagggcctccagccggtggtgggaccccaaattcgactccgtgaacctg gaggaggcctgcctggagcgctgctttccgcagacccagcgccgcttccggtacgcactc ttttatgtgggcttcgcctgccttctctggagcatctatttcgctgtccacatgagatcc aaagtgattgtcatggtggtcccggctctgtgcttcctggtggtatgtgtgggctttttc ctgtttactttcaccaagctgtacgcccggcattatgcgtggacctcgctggctctcacc ctgctggtgttcgccctgaccctggctgcgcagtttcaggtttggacacctctgtcggga cgtgttgacagccccaatcatactctcacggccaaggcggcggacacttgcttatctcaa gtggggagcttctccatgtgcatcgaagtgctctttttgctttacacggtcatgcattta cctctgtacctgagcttgtttttgggggtggtctattctgtcctttttgagaccttcggt taccatttccgaaatgaagactgctttccttccccggaccccggggccctgcactgggag ctgctgagcagagccctgctccacgtgtgcatccatgccattgggatccatctgtttgtc atgtctcaggtgaggtccaggagcaccttcctcaaggtaggacaatccattatgcacggc aaagatctggaagtagagaaagccctgaaggagaggatgattcactccgtgatgccgaga atcatagctgacgacttaatgaagcagggggatgaggagagcgagaattctgtcaagagg cacgccacctccagtcccaagaacaggaagaagaaggcctccatccagaaagcgcccata gcattccgcccctttaagatgcagcagattgaagaagtcagtattttatttgcagacatc gtggggttcaccaagatgagtgctaacaaatctgctcacgccttggtagggctactcaat gatctgttcggccgcttcgaccggttgtgcgaggagaccaagtgtgaaaagatcagcacc ctgggagactgttactactgtgtggcagggtgtccggagccccgggcagaccatgcctac tgctgtatcgagatgggcttaggcatgataaaagccatcgagcagttctgccaggagaag aaagagatggtgaacatgcgagtcggggttcacacggggacggtcttgtgtggcatcctg ggcatgaggaggtttaaatttgatgtgtggtccaatgatgtgaacttggctaacctcatg gagcagctgggagtggccggcaaagtccacatatccgaggccactgcaaaatacttagac gacaggtacgaaatggaagatgggagagttatggagcgtcttgggcagagtgtggtcgct gaccagttgaaaggtttgaagacatacctgatatcgggtcagagagccaaggagtcccac tgcagctgtgcagaggccctgctttctggctttgaggtcattgacgactcacgggtgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacttgcccttcatgtggaatcacatttgctcccaaa tctgaagctggtgcagaaggaggagctgtgcaaaatggctgtcaagacgagcctaaggcc agcaccaaggtaacaagctcatggctgttgttcctgtcagtacctctcctggcgcatcca cctaaggcttctggaggacccaactccaaaacccagaacggactcctgagccctcctgca gaggagaagctcaccaacagccagacctccctctgtgagatactgcaggagaagggacgg tgggcaggcgtgagcttggaccagtcagccctcctcccgctcaggttcaagaacatccgt gagaaaactgacgcccactttgtcgatgtcatcaaagaagacagcctgatgaaagattat ttcttcaagccgcccatcagtcagttcagcctgaacttcctggaccaggagctggagcaa tcctacagagccagctaccaggaagaggtcataaagaactctcccgtgaagacgtttgcc agtgccaccttcagctcccttctggatgtgtttctgtcaaccacggtgttcctgattctc tccatcacctgcttcctaaagtacggagccaccgccacccctcccccaccggctgccctg gccgtctttggtgcagacctgctgctggaggtgctttctctcatagtgtccatcagaatg gtgttcttcctggaggatgtcctgacgtgtacaaagcgcttgctggaatggatcgctggc tggctccctcgccactgcattggggccatcttggtgtcacttcctgccctggctgtctat tcacacatcacctccgagtttgagaccaacataaatttcaccatgctcacgggctctgca gtgctggtggccgtcgtgcactactgtaacttctgccagctcagctcctggatgaggtcc tccctcgccacccttgtgggggctgggccgctgcttctgctctacatctcgctatgccag gacagttccattgtgatgtcacccttggacacagcacagaatttcagtgcctccgagagg agcccgtgcaacagctcagtgctgcaggacggcaggaggccggccagcctcataggcaag gagctcatcctcaccttcttcctcctgctcctcttggtctggttcctgaaccgggagttc gaggtgagctaccggctgcactaccacggggatgtggaagcagacctacaccgcaccaag atccagagcatgagagaccaggccgactggctgctacggaacatcatcccctaccacgtg gcggagcagctcaaggtctcgcagacctactccaagaaccatgacagcgggggagtgatc tttgccagcatcgtcaacttcagtgaattctacgaggagaactatgaggggggcaaggaa tgctaccgcgtcctcaatgagctgatcggtgacttcgacgagctcttgagcaagccggac tataatagcatcgagaagatcaagaccatcggggccacgtatatggcagcctcggggctg aacacggcccagtgccaggagggcggccacccacaggagcacctgcgtatcctcttcgag ttcgccaaggagatgatgcgcgtggtggatgacttcaacaacaacatgctctggttcaac ttcaagctcagggtcggcttcaaccacgggcccctcacggcaggtgtcatcggcaccacc aagctgctgtatgacatctggggggacaccgtcaacatcgccagcaggatggacaccacc ggggtggagtgccgaatccaggtgagcgaggagagctaccgcgtgctgagcaagatgggt tacgactttgactaccgagggaccgtgaacgtcaaggggaaagggcagatgaagacatac ctttacccgaagtgcacggacaatggagtggtccctcagcaccagctgtccatctccccg gacatccgcgtccaggtggacggcagcattgggcggtctcccacagatgagatcaccaac ttggtgccttctgttcagtatctggacaaggcttccctggggtctgacgatggggcgcag accaaggaagcgaccctgtcctctaagaggccctggagagagccagtcaaagcagaggag aggtttcgatttggcaaagccatagagaaggaagactgtgaagacacaggcgcagaagag gccaatgaactcaccaagctcaacgtctcaaagagtgtgtga

Rattus norvegicus (rat): 305509 Help Entry 305509            CDS       T01003                                  Gene name Adcy1, Ac1 Definition (RefSeq) adenylate cyclase 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04720   Long-term potentiation rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05142   Chagas disease rno05146   Amoebiasis rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     305509 (Adcy1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     305509 (Adcy1)    04371 Apelin signaling pathway     305509 (Adcy1)    04020 Calcium signaling pathway     305509 (Adcy1)    04072 Phospholipase D signaling pathway     305509 (Adcy1)    04024 cAMP signaling pathway     305509 (Adcy1)    04022 cGMP-PKG signaling pathway     305509 (Adcy1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     305509 (Adcy1)   09144 Cellular community - eukaryotes    04540 Gap junction     305509 (Adcy1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     305509 (Adcy1)    04062 Chemokine signaling pathway     305509 (Adcy1)   09152 Endocrine system    04911 Insulin secretion     305509 (Adcy1)    04923 Regulation of lipolysis in adipocytes     305509 (Adcy1)    04912 GnRH signaling pathway     305509 (Adcy1)    04913 Ovarian steroidogenesis     305509 (Adcy1)    04915 Estrogen signaling pathway     305509 (Adcy1)    04914 Progesterone-mediated oocyte maturation     305509 (Adcy1)    04921 Oxytocin signaling pathway     305509 (Adcy1)    04926 Relaxin signaling pathway     305509 (Adcy1)    04935 Growth hormone synthesis, secretion and action     305509 (Adcy1)    04918 Thyroid hormone synthesis     305509 (Adcy1)    04928 Parathyroid hormone synthesis, secretion and action     305509 (Adcy1)    04916 Melanogenesis     305509 (Adcy1)    04925 Aldosterone synthesis and secretion     305509 (Adcy1)    04927 Cortisol synthesis and secretion     305509 (Adcy1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     305509 (Adcy1)    04270 Vascular smooth muscle contraction     305509 (Adcy1)   09154 Digestive system    04970 Salivary secretion     305509 (Adcy1)    04971 Gastric acid secretion     305509 (Adcy1)    04972 Pancreatic secretion     305509 (Adcy1)    04976 Bile secretion     305509 (Adcy1)   09156 Nervous system    04724 Glutamatergic synapse     305509 (Adcy1)    04727 GABAergic synapse     305509 (Adcy1)    04725 Cholinergic synapse     305509 (Adcy1)    04720 Long-term potentiation     305509 (Adcy1)    04723 Retrograde endocannabinoid signaling     305509 (Adcy1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     305509 (Adcy1)   09149 Aging    04211 Longevity regulating pathway     305509 (Adcy1)    04213 Longevity regulating pathway - multiple species     305509 (Adcy1)   09159 Environmental adaptation    04713 Circadian entrainment     305509 (Adcy1)    04714 Thermogenesis     305509 (Adcy1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     305509 (Adcy1)   09165 Substance dependence    05032 Morphine addiction     305509 (Adcy1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     305509 (Adcy1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     305509 (Adcy1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     305509 (Adcy1)    05163 Human cytomegalovirus infection     305509 (Adcy1)   09174 Infectious disease: parasitic    05146 Amoebiasis     305509 (Adcy1)    05142 Chagas disease     305509 (Adcy1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     305509 (Adcy1) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      305509 (Adcy1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  305509 NCBI-ProteinID:  NP_001100709 RGD:  1309318 Ensembl:  ENSRNOG00000059479 UniProt:  D4A3N4 LinkDB All DBs Position 14q21 AA seq 967 aa AA seqDB search MGSAVAEQGVWQLLLVTFVSYALLPVRSLLAIGFGLVVAASHLLVTAALVPAKRPRLWRT LGANALLFFGVNMYGVFVRILTERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPR NVAMEMKEDFLKPPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFG KFDELATENHCRRIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDL NMRVGLHTGRVLCGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYE VEPGHGHERNTFLRTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMH CRKMFKAEIPFSNVMTCEDDDKRRALRTASEKLRNRSSFSTNVVYTTPGTRVNRYISRLL EARQTELEMADLNFFTLKYKHVEREQKYHQLQDEYFTSAVVLALILATLFGLIYLLVIPQ SVAVLLLLVFSICFLVACTLYLHITRVQCFPGCLTIQIRTALCVFIVVLIYSVAQGCVVS CLPWAWSSHSNSSLVVLAAGGRRTVLPALPCESAHHGLLCCLVGTLPLAIFLRVSSLPKM ILLSGLTTSYILVLELSGYTKVGGGALSGRSYEPIMAILLFSCTLALHARQVDVRLRLDY LWAAQAEEERDDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFAS IPNFNDFYIELDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLA PTAGTRAKKSISSHLSTLADFAIDMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARR PQYDIWGNTVNVASRMDSTGVQGRIQVTEEVHRLLNRCSYQFVCRGKVSVKGKGEMLTYF LEGRTDGSSSHSRSLRLERRMFPYGRGGGGQARRPPLCPAAGPPIKPGLSPAPTSQYLSS TAAGKEA NT seq 2904 nt NT seq  +upstreamnt  +downstreamnt atgggctcggcggttgccgaacagggggtttggcaactccttttggtcaccttcgtgtcc tatgccttgctgcccgtgcgcagcctactggccatcggcttcgggctcgtggtggctgcc tcgcacttactggtcacagccgccttggtccctgccaagcgcccacgtctctggaggacg cttggtgccaatgccctgctcttctttggtgtgaacatgtatggcgtcttcgtgcggatc ttgactgagcgctcccagaggaaggccttcctgcaggctcgaaactgcattgaggaccgg ctgcggctggaagatgagaatgagaaacaggagcggttgctcatgagcctcttgccccgg aatgtcgccatggagatgaaggaagacttcctgaagccccctgagaggatatttcacaag atttacatccagaggcacgacaatgtgagcatcctgtttgcagacatcgtgggtttcaca ggtctggcgtcccagtgcacggcccaggagctggtgaaactgctcaatgaactctttggc aagttcgatgagttagccacggaaaaccactgtcgccgaatcaagatccttggagactgc tactactgtgtgtctggcctcacccagcccaagacggatcacgcccactgctgtgtggag atgggacttgacatgatcgataccatcacatccgtggctgaggctactgaagtagacctg aacatgcgtgtgggcctacacactggcagggtcctctgtggtgtcctgggcctacgcaag tggcagtacgacgtatggtccaacgacgtcaccctggccaatgtcatggaggctgctggc ttaccagggaaggtccacatcacgaagacaacccttgcgtgcttgaacggggactacgag gtggagccgggccacggccatgagaggaacacctttctgagaactcacaacatcgagacc ttctttattgtgccatcccatcggaggaagatatttccaggtttgattctctcggatatc aaaccagccaagaggatgaagttcaagaccgtctgctacctgctggtgcagctcatgcat tgccggaaaatgttcaaggctgagatccccttctccaacgtaatgacctgtgaggatgat gacaagcgaagggcattgagaacggcctcggagaagctcagaaaccgttcgtcattctct accaacgtggtctacaccactccgggtacgcgtgtcaacaggtacatcagccgccttctt gaagcccgccagacagagctggagatggccgacctgaacttctttaccctcaagtacaag catgttgaacgggaacaaaaataccaccagcttcaagatgagtacttcaccagcgccgtt gtcctcgccctcatcctggctaccttatttgggcttatctaccttctggtaatcccacag agcgtggctgtcctgctgctgctggtgttttctatctgcttcttggtggcctgtaccctg tacctgcacatcacgagggtccagtgttttccagggtgcctgaccatccagatccgcacc gctctgtgtgtgttcatcgtggtcttaatctactcagtagctcaaggatgtgtggtgagc tgtctgccttgggcctggagctctcactccaacagctccctagtggtcctcgcagctggt ggccggcgcactgtgctgcctgccctgccctgtgagtctgcacaccatggcctgctctgc tgcctggtgggcaccctcccactagccatattcctgcgggtgtcctccttgccaaagatg atcctgctgtctgggctgacgacttcctacatccttgtcctggagctcagtggatacacc aaggttgggggcggtgccctctctgggcgcagctatgagcccatcatggctatcctgctg ttctcatgcacgctggccctgcacgccaggcaggtggacgtcaggctacggctggactac ctctgggcagcacaggcggaggaggaacgggacgacatggagagggtaaagctggacaac aagaggatcctcttcaacctcctgccagcgcacgtcgcacagcacttcctcatgtccaat ccccggaacatggatctctattaccagtcctactcccaggtgggcgtcatgttcgcctcc atccccaacttcaacgacttctacatagaactggatggcaacaacatgggcgttgagtgt ctgcggctcctcaatgagatcattgctgactttgatgagctcatggacaaggacttctac aaggacctggagaagatcaagaccattgggagtacctatatggctgccgtggggctggcg cccacagcaggaaccagggctaagaagtccatctcttcccatctgagcacgctggcagac tttgccatcgacatgtttgatgtcctggatgagatcaactaccagtcctacaacgacttc gttctccgagtcggcatcaacgttggccccgtggtcgctggagtgatcggtgctcgcagg ccccagtacgacatctggggaaacacagtcaatgtggccagtcggatggatagcactggg gtccagggaagaattcaggtgactgaggaagtccaccgactgctgaacaggtgctcatac cagtttgtgtgcagaggcaaagtcagcgtcaagggcaagggagagatgctaacgtacttt ctagaaggcaggactgatgggagcagttcccacagcaggtcccttcgcttggagcgaagg atgtttccttatgggagaggcggcggaggccaggccaggcggcccccattgtgtcctgca gctggacccccaatcaaaccggggctctctccagcccccactagccagtacctgtcatcc acagcagcagggaaggaagcctag

Rattus norvegicus (rat): 54223 Help Entry 54223             CDS       T01003                                  Gene name Adcy4 Definition (RefSeq) adenylate cyclase 4   KO K08044   adenylate cyclase 4 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04742   Taste transduction rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     54223 (Adcy4)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     54223 (Adcy4)    04371 Apelin signaling pathway     54223 (Adcy4)    04020 Calcium signaling pathway     54223 (Adcy4)    04072 Phospholipase D signaling pathway     54223 (Adcy4)    04024 cAMP signaling pathway     54223 (Adcy4)    04022 cGMP-PKG signaling pathway     54223 (Adcy4)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     54223 (Adcy4)   09144 Cellular community - eukaryotes    04540 Gap junction     54223 (Adcy4)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     54223 (Adcy4)    04062 Chemokine signaling pathway     54223 (Adcy4)   09152 Endocrine system    04911 Insulin secretion     54223 (Adcy4)    04923 Regulation of lipolysis in adipocytes     54223 (Adcy4)    04912 GnRH signaling pathway     54223 (Adcy4)    04913 Ovarian steroidogenesis     54223 (Adcy4)    04915 Estrogen signaling pathway     54223 (Adcy4)    04914 Progesterone-mediated oocyte maturation     54223 (Adcy4)    04921 Oxytocin signaling pathway     54223 (Adcy4)    04926 Relaxin signaling pathway     54223 (Adcy4)    04935 Growth hormone synthesis, secretion and action     54223 (Adcy4)    04918 Thyroid hormone synthesis     54223 (Adcy4)    04928 Parathyroid hormone synthesis, secretion and action     54223 (Adcy4)    04916 Melanogenesis     54223 (Adcy4)    04925 Aldosterone synthesis and secretion     54223 (Adcy4)    04927 Cortisol synthesis and secretion     54223 (Adcy4)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     54223 (Adcy4)    04270 Vascular smooth muscle contraction     54223 (Adcy4)   09154 Digestive system    04970 Salivary secretion     54223 (Adcy4)    04971 Gastric acid secretion     54223 (Adcy4)    04972 Pancreatic secretion     54223 (Adcy4)    04976 Bile secretion     54223 (Adcy4)   09156 Nervous system    04724 Glutamatergic synapse     54223 (Adcy4)    04727 GABAergic synapse     54223 (Adcy4)    04725 Cholinergic synapse     54223 (Adcy4)    04723 Retrograde endocannabinoid signaling     54223 (Adcy4)   09157 Sensory system    04742 Taste transduction     54223 (Adcy4)    04750 Inflammatory mediator regulation of TRP channels     54223 (Adcy4)   09149 Aging    04211 Longevity regulating pathway     54223 (Adcy4)    04213 Longevity regulating pathway - multiple species     54223 (Adcy4)   09159 Environmental adaptation    04713 Circadian entrainment     54223 (Adcy4)    04714 Thermogenesis     54223 (Adcy4)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     54223 (Adcy4)   09165 Substance dependence    05032 Morphine addiction     54223 (Adcy4)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     54223 (Adcy4)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     54223 (Adcy4)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     54223 (Adcy4)    05163 Human cytomegalovirus infection     54223 (Adcy4)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     54223 (Adcy4) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      54223 (Adcy4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N CD52 Motif Other DBs NCBI-GeneID:  54223 NCBI-ProteinID:  NP_062158 RGD:  2034 Ensembl:  ENSRNOG00000020401 UniProt:  Q66HK5 LinkDB All DBs Position 15p13 AA seq 1072 aa AA seqDB search MARLFSPRPPPSEDLFYETYYSLSQQYPLLILLLVIVLCAIVALPAVAWASGRELTSDPS FLTTVLCALGGFSLLLGLASREQQLQRWTRPLSGLIWAALLALGYGFLFTGGVVSAWDQV SFFLFIIFTVYAMLPLGMRDAAAAGVISSLSHLLVLGLYLGWRPESQRDLLPQLAANAVL FLCGNVVGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK AEIMARLQAGQSSRPENTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRVATG VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG AYAVERADMEHRDPYLRELGEPTYLVIDPWAEEEDEKGTERGLLSSLEGHTMRPSLLMTR YLESWGAAKPFAHLSHVDSPASTSTPLPEKAFSPQWSLDRSRTPRGLHDELDTGDAKFFQ VIEQLNSQKQWKQSKDFNLLTLYFREKEMEKQYRLSALPAFKYYAACTFLVFLSNFTIQM LVTTRPPALATTYSITFLLFLLLLFVCFSEHLTKCVQKGPKMLHWLPALSVLVATRPGLR VALGTATILLVFTMAVVSLLFLPVSSDCPFLAPNVSSVAFNTSWELPASLPLISIPYSMH CCVLGFLSCSLFLHMSFELKLLLLLLWLVASCSLFLHSHAWLSDCLIARLYQGSLGSRPG VLKEPKLMGAIYFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLE NVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASIPDFKEFYSESNINHEGLECLRLLN EIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATPGQDTQQDAERSCSHLGTMVEFA VALGSKLGVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVL GKIQVTEETARALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRTGSPSAS NT seq 3219 nt NT seq  +upstreamnt  +downstreamnt atggcccgcctcttcagtccccggcctcctcccagcgaagatctcttctacgagacttac tacagcctgagccaacagtatccactgctaattctgcttctggtcattgtgctctgcgcg atcgtggcactgcccgccgtcgcctgggccagcggcagggagctgacctcagacccaagc ttcctgacaactgtgctgtgtgctttgggtggcttctccctgcttttggggctcgcttcc cgggagcagcaactgcagcgatggacacgacctctttctggcctcatatgggctgcattg ctggctctgggctatgggtttctattcactgggggtgtggtgagcgcctgggatcaggtg tcctttttcctcttcatcattttcaccgtgtacgccatgctgcccttgggcatgcgggat gctgctgccgcgggggtcatctcatccctctcacacctgctggtccttggactgtacctt gggtggcggcctgagtcgcagagggatctgctaccacagttggcagcgaatgcggtgttg ttcctgtgtgggaacgtggtgggagcataccacaaggccctgatggagcgagcattgcgc gccacgttccgggaggctcttagctccctgcattcacgccggaggttggacactgagaaa aagcaccaggagcacctcctcttgtctatccttcctgcctacctggcccgagagatgaag gcagagatcatggctcggctgcaggctggacagagctcacggccagagaacacaaacaac tttcacagcctgtatgtcaagaggcaccaaggagtgagtgtgctgtatgctgacatcgtg ggcttcacacggctggccagtgagtgttcccctaaggagctggtgctaatgctcaatgaa ctcttcggcaaattcgaccaaattgcaaaggagcacgaatgcatgcggatcaagatcctg ggagactgttactactgtgtatccgggctgcccctctctctgcctgaccacgccatcaat tgcgtgcgcatgggactggacatgtgccgggccatcaggaaacttcgggtagccaccggt gtggatatcaacatgcgtgtcggtgtgcactcaggcagcgtcctctgtggagtcatcggg ctacagaagtggcagtatgatgtctggtcccatgatgtcacattggccaaccatatggaa gcaggcggcgttccaggacgagtgcacatcacaggggccacgctggccctgctggcagga gcttatgctgtggagagagcagacatggagcatcgagacccataccttcgggagctaggg gaacccacatacctggtcattgatccttgggctgaggaggaagacgagaagggcaccgag agaggattgctgtcttctctagaggggcacacgatgcgtccgtcactactgatgactcgt tatctggagtcttggggtgcagccaagcctttcgcccacctaagccacgtcgacagtcct gcatccacatccactccactcccggagaaagccttcagcccccagtggagcctggaccgg agtcgcaccccccgcgggctacacgatgaactggacactggagatgccaagttcttccag gtcatcgaacaactcaactctcaaaaacagtggaaacagtcgaaggacttcaacctcctg acgctctacttcagagagaaggagatggagaaacagtatcggctgtctgcgctccccgcc ttcaaatactacgcagcctgcaccttcctggtttttctgtccaacttcacaatccaaatg ctggtgacaaccaggcccccagctctggccaccacctacagcatcaccttccttctcttc cttctcctcctcttcgtctgcttctcagagcacctgacgaagtgcgtccagaaaggcccc aagatgttgcactggctgcctgcgctgtctgtcctggtggccacacggccgggattgcga gtagccctgggcacagccaccatcctcctggtgttcactatggccgtcgtcagcctgctc ttcttaccagtgtcgtcagactgccctttcctggctcccaatgtgtcgtcagtggctttt aatacttcctgggagctgccagcatccctgcctctcatcagcatcccatactccatgcat tgttgcgtgctgggtttcctttcctgctccctttttctgcacatgagcttcgaactgaag ctgcttctgcttctgctgtggctggtggcatcttgttccctatttctgcactcccacgcc tggctgtccgactgcctcattgcccgcctttatcaaggctcattgggctccaggccgggg gtactgaaggaaccgaaactgatgggagctatctacttcttcatcttcttcttcacactc ctcgtcctggctcggcagaatgagtattactgtcgcctggacttcctatggaaaaagaaa ctgaggcaggagcgagaggaaactgagacaatggagaacctgacccggctcctcctggag aatgtactccctgcacacgtggcgccccagttcatcggccagaaccggcgcaatgaggac ctctaccatcagtcgtacgaatgtgtttgtgtcctctttgcatccatcccagactttaag gaattctactcggaatccaacatcaaccatgaggggctagagtgtctgcggctgctcaat gagatcattgccgactttgatgagctgctctccaagccaaagttcagtggagtagagaag atcaaaactatcggcagcacctacatggcggccacaggcctaaatgccacccctgggcag gacacacaacaggacgctgagagaagctgcagccatctgggcaccatggtggaatttgca gtggccctggggtctaagctgggtgtcatcaataagcactcgttcaacaacttccgcctg cgtgtggggttaaaccatggaccagtcgtagcaggggtgattggggcgcagaagccacaa tatgacatctgggggaatacagtgaacgtggccagccgcatggagagcacaggagttctc ggcaagatccaagtgaccgaggagacagctagggctctgcaatccctgggttacacatgc tacagccgaggtgtcatcaaggtcaagggcaaagggcaactctgtacctacttcctgaac acagacctgacacgaaccggatctccctcagcatcctag

Rattus norvegicus (rat): 64508 Help Entry 64508             CDS       T01003                                  Gene name Adcy3 Definition (RefSeq) adenylate cyclase 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04740   Olfactory transduction rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04962   Vasopressin-regulated water reabsorption rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     64508 (Adcy3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     64508 (Adcy3)    04371 Apelin signaling pathway     64508 (Adcy3)    04020 Calcium signaling pathway     64508 (Adcy3)    04072 Phospholipase D signaling pathway     64508 (Adcy3)    04024 cAMP signaling pathway     64508 (Adcy3)    04022 cGMP-PKG signaling pathway     64508 (Adcy3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     64508 (Adcy3)   09144 Cellular community - eukaryotes    04540 Gap junction     64508 (Adcy3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     64508 (Adcy3)    04062 Chemokine signaling pathway     64508 (Adcy3)   09152 Endocrine system    04911 Insulin secretion     64508 (Adcy3)    04923 Regulation of lipolysis in adipocytes     64508 (Adcy3)    04912 GnRH signaling pathway     64508 (Adcy3)    04913 Ovarian steroidogenesis     64508 (Adcy3)    04915 Estrogen signaling pathway     64508 (Adcy3)    04914 Progesterone-mediated oocyte maturation     64508 (Adcy3)    04921 Oxytocin signaling pathway     64508 (Adcy3)    04926 Relaxin signaling pathway     64508 (Adcy3)    04935 Growth hormone synthesis, secretion and action     64508 (Adcy3)    04918 Thyroid hormone synthesis     64508 (Adcy3)    04928 Parathyroid hormone synthesis, secretion and action     64508 (Adcy3)    04916 Melanogenesis     64508 (Adcy3)    04925 Aldosterone synthesis and secretion     64508 (Adcy3)    04927 Cortisol synthesis and secretion     64508 (Adcy3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     64508 (Adcy3)    04270 Vascular smooth muscle contraction     64508 (Adcy3)   09154 Digestive system    04970 Salivary secretion     64508 (Adcy3)    04971 Gastric acid secretion     64508 (Adcy3)    04972 Pancreatic secretion     64508 (Adcy3)    04976 Bile secretion     64508 (Adcy3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     64508 (Adcy3)   09156 Nervous system    04724 Glutamatergic synapse     64508 (Adcy3)    04727 GABAergic synapse     64508 (Adcy3)    04725 Cholinergic synapse     64508 (Adcy3)    04723 Retrograde endocannabinoid signaling     64508 (Adcy3)   09157 Sensory system    04740 Olfactory transduction     64508 (Adcy3)    04750 Inflammatory mediator regulation of TRP channels     64508 (Adcy3)   09149 Aging    04211 Longevity regulating pathway     64508 (Adcy3)    04213 Longevity regulating pathway - multiple species     64508 (Adcy3)   09159 Environmental adaptation    04713 Circadian entrainment     64508 (Adcy3)    04714 Thermogenesis     64508 (Adcy3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     64508 (Adcy3)   09165 Substance dependence    05032 Morphine addiction     64508 (Adcy3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     64508 (Adcy3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     64508 (Adcy3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     64508 (Adcy3)    05163 Human cytomegalovirus infection     64508 (Adcy3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     64508 (Adcy3) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      64508 (Adcy3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA NCE101 Peptidase_S49_N Motif Other DBs NCBI-GeneID:  64508 NCBI-ProteinID:  NP_570135 RGD:  71009 Ensembl:  ENSRNOG00000003999 UniProt:  P21932 G3V6I2 LinkDB All DBs Position 6q14 AA seq 1144 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGVGLVLDII LFVLCKKGLLPDRVSRKVVPYLLWLLITAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYLCAIIVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCD YLDEKGIETYLIIASKPEVKKTAQNGLNGSALPNGAPASKPSSPALIETKEPNGSAHASG STSEEAEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQV VKKRNTFLLTMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTAMVEILIDPWLMTNYV TFVVGEVLLLILTICSMAAIFPRAFPKKLVAFSSWIDRTRWARNTWAMLAIFILVMANVV DMLSCLQYYMGPYNVTTGIELDGGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLL VTGAVTAINLYAWCPVFDEYDHKRFQEKDSPMVALEKMQVLSTPGLNGTDSRLPLVPSKY SMTVMMFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHV ARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFD SLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLADLADFA LAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVM GNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNGSSVTLPHQV VDNP NT seq 3435 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctcggatcccgagtactcggcagagtactcagccgagtac tcagtcagcttgccctctgaccccgaccgcggggtcggccggacccatgaaatttctgtg cggaactctgggtcctgcctgtgcctgcctcgctttatgcggctgaccttcgtgcctgag tccttggagaacctctaccagacctactttaaaaggcagcgccatgagacactgctggtg ctggtggtctttgcggccctctttgactgctacgtggtagtgatgtgcgcggtggtcttt tccagcgacaagctggcgcccctcatggtggcaggcgtcggtctggtgttggacatcatc cttttcgtgctctgcaaaaaggggctgctcccggatcgagtgagccgcaaagtggtaccc tacctgctgtggctgctcatcacagcccagatcttctcctacctgggcctgaacttttcg cgtgcccacgcagccagtgacactgtgggttggcaggccttctttgtcttctccttcttc ataacgctgccactcagcctcagccccatcgtgatcatctccgtggtctcctgtgttgtg catacgcttgtcttgggggtcacggtggcccagcagcagcaagacgagctagaagggatg cagctgctgagggagatcctggctaacgtcttcctctacctgtgcgccatcatcgtgggc atcatgtcctactacatggcagaccgtaagcaccgaaaggccttcctggaggcccgccag tcgctggaggtgaagatgaatctggaggagcagagccagcagcaggaaaaccttatgctt tccatcctgccaaagcatgtggctgacgagatgttgaaggacatgaagaaagatgagagt cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaatgtcagcatc ctgtttgcagatattgtgggctttacccagctgtcctctgcttgcagtgcccaggagctc gtgaagctactcaacgagctctttgcccgctttgacaagctggcggccaaataccaccag ctgaggatcaagatcctaggcgactgttactactgcatctgcggcctgcctgactaccgg gaggaccacgccgtgtgctccatcctgatggggcttgccatggtagaggccatctcgtac gtgcgggagaagaccaagaccggagtggacatgcgtgtgggggtgcacacaggcactgtg ctaggtggcgtcctgggccagaagcgctggcagtatgatgtatggtctaccgatgtcact gtggcaaacaagatggaggctggcggcatcccagggcgcgtgcacatttcccagagcacc atggactgcctgaaaggggagttcgatgtcgaacctggtgatggtggcagtcgctgcgac tacctagatgagaagggcatcgaaacctacctcatcattgcctccaagccagaggtgaag aagacagctcaaaatggcctcaacggctcggccctgccaaacggagcaccggcatccaag cccagctcccctgcccttattgagaccaaggagcccaatgggagtgcccatgccagcggc tccacatcagaggaggctgaagaacaggaggcccaggctgacaacccctcgttccccaac ccccgccgcaggctgcgcctccaggacctggcagaccgtgtggtggacgcctctgaggat gagcacgaactgaaccagcttcttaacgaggccctgctggagcgggagtccgcccaggtg gtaaagaagagaaacacattcctcctaacgatgaggttcatggacccagagatggaaaca cgctactcggtggagaaggagaagcagagtggggctgccttcagctgttcctgtgtggtc cttttctgcacggccatggtggagatacttatcgacccctggttgatgacaaactacgtg accttcgtggttggagaggttctgctcttgatcctgaccatctgttcgatggctgccatc ttccccagggcatttcctaagaagctcgtggccttctcatcttggattgaccggacccgc tgggccagaaatacctgggccatgttagccatcttcattctggttatggccaatgttgtg gacatgctgagctgtctccagtactacatgggaccttacaacgtgacaaccgggatagag ctggacggtggctgtatggagaaccccaagtactacaactatgttgctgtgctgtccctc atcgccaccatcatgctggtgcaggtcagccacatggtgaagctgacactcatgctgctc gtcacaggcgccgtgactgccatcaacctgtatgcctggtgtcctgtctttgatgaatac gaccacaaacgctttcaggaaaaggactctcctatggtggccttagagaagatgcaggta ctttccacccctgggctcaatggcactgacagcaggctgcccctggtgccttccaagtac tcgatgactgtgatgatgttcgttatgatgctgagcttttactacttctcacgccacgtg gagaaactggcccggacactgttcttgtggaagattgaggtccatgaccagaaagaacgt gtgtacgagatgcgccggtggaacgaggccttggtcaccaacatgttgccagagcatgtt gcacgccatttcctgggctccaagaagagagatgaggagctgtacagccagtcttatgac gagattggagtcatgtttgcctccttgcccaactttgccgacttctacactgaggagagc atcaataatggtggcatcgagtgtctacgcttcctcaatgagatcatctctgattttgac tctctcctggacaatcccaaattccgggtcatcaccaagatcaaaaccatcggcagcacc tatatggcagcttctggagtcacaccagatgtcaacaccaatggctttacaagctccagc aaggaggaaaagtcagacaaggagcgctggcagcacctggctgacctggcagactttgca ctagccatgaaggacacgcttacaaacatcaacaaccagtcattcaacaacttcatgctg cgcataggcatgaacaaaggaggagttctggctggagtcattggagcccggaagccacac tatgacatctgggggaacacggtcaatgtggccagcaggatggaatccacaggggtcatg ggcaatatccaggtggtagaagagacacaggtcatccttcgagagtatggcttccgcttt gtgaggcgaggacccatctttgtgaagggcaaaggggagcttctgacctttttcttaaag gggcgggacaggccagctgccttccccaatggctcctctgttacactgccccaccaagtg gtggacaacccctga

Rattus norvegicus (rat): 64532 Help Entry 64532             CDS       T01003                                  Gene name Adcy5 Definition (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04726   Serotonergic synapse rno04727   GABAergic synapse rno04728   Dopaminergic synapse rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04924   Renin secretion rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05012   Parkinson disease rno05030   Cocaine addiction rno05031   Amphetamine addiction rno05032   Morphine addiction rno05034   Alcoholism rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     64532 (Adcy5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     64532 (Adcy5)    04371 Apelin signaling pathway     64532 (Adcy5)    04072 Phospholipase D signaling pathway     64532 (Adcy5)    04024 cAMP signaling pathway     64532 (Adcy5)    04022 cGMP-PKG signaling pathway     64532 (Adcy5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     64532 (Adcy5)   09144 Cellular community - eukaryotes    04540 Gap junction     64532 (Adcy5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     64532 (Adcy5)    04062 Chemokine signaling pathway     64532 (Adcy5)   09152 Endocrine system    04911 Insulin secretion     64532 (Adcy5)    04923 Regulation of lipolysis in adipocytes     64532 (Adcy5)    04912 GnRH signaling pathway     64532 (Adcy5)    04913 Ovarian steroidogenesis     64532 (Adcy5)    04915 Estrogen signaling pathway     64532 (Adcy5)    04914 Progesterone-mediated oocyte maturation     64532 (Adcy5)    04921 Oxytocin signaling pathway     64532 (Adcy5)    04926 Relaxin signaling pathway     64532 (Adcy5)    04935 Growth hormone synthesis, secretion and action     64532 (Adcy5)    04918 Thyroid hormone synthesis     64532 (Adcy5)    04928 Parathyroid hormone synthesis, secretion and action     64532 (Adcy5)    04916 Melanogenesis     64532 (Adcy5)    04924 Renin secretion     64532 (Adcy5)    04925 Aldosterone synthesis and secretion     64532 (Adcy5)    04927 Cortisol synthesis and secretion     64532 (Adcy5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     64532 (Adcy5)    04270 Vascular smooth muscle contraction     64532 (Adcy5)   09154 Digestive system    04970 Salivary secretion     64532 (Adcy5)    04971 Gastric acid secretion     64532 (Adcy5)    04972 Pancreatic secretion     64532 (Adcy5)    04976 Bile secretion     64532 (Adcy5)   09156 Nervous system    04724 Glutamatergic synapse     64532 (Adcy5)    04727 GABAergic synapse     64532 (Adcy5)    04725 Cholinergic synapse     64532 (Adcy5)    04728 Dopaminergic synapse     64532 (Adcy5)    04726 Serotonergic synapse     64532 (Adcy5)    04723 Retrograde endocannabinoid signaling     64532 (Adcy5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     64532 (Adcy5)   09149 Aging    04211 Longevity regulating pathway     64532 (Adcy5)    04213 Longevity regulating pathway - multiple species     64532 (Adcy5)   09159 Environmental adaptation    04713 Circadian entrainment     64532 (Adcy5)    04714 Thermogenesis     64532 (Adcy5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     64532 (Adcy5)   09164 Neurodegenerative disease    05012 Parkinson disease     64532 (Adcy5)   09165 Substance dependence    05030 Cocaine addiction     64532 (Adcy5)    05031 Amphetamine addiction     64532 (Adcy5)    05032 Morphine addiction     64532 (Adcy5)    05034 Alcoholism     64532 (Adcy5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     64532 (Adcy5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     64532 (Adcy5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     64532 (Adcy5)    05163 Human cytomegalovirus infection     64532 (Adcy5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     64532 (Adcy5) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      64532 (Adcy5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Motif Other DBs NCBI-GeneID:  64532 NCBI-ProteinID:  NP_072122 RGD:  71014 Ensembl:  ENSRNOG00000002229 UniProt:  Q04400 LinkDB All DBs Position 11q22 AA seq 1262 aa AA seqDB search MSGSKSVSPPGYAAQTAASPAPRGGPEHRAAWGEADSRANGYPHAPGGSTRGSTKRSGGA VTPQQQQRLASRWRGGDDDEDPPLSGDDPLVGGFGFSFRSKSAWQERGGDDGGRGSRRQR RGAAGGGSTRAPPAGGSGSSAAAAAAAGGTEVRPRSVEVGLEERRGKGRAAEELEPGTGT VEDGDGSEDGGSSVASGSGTGTVLSLGACCLALLQIFRSKKFPSDKLERLYQRYFFRLNQ SSLTMLMAVLVLVCLVMLAFHAARPPLQVVYLAVLAAAVGVILIMAVLCNRAAFHQDHMG LACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVLSGVLLSA LHLAISLHTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETRECIQARL HSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILFADIEGFT SLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARADHAHCCVE MGMDMIEAISSVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANHMEAGG KAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEEKAMIAKM NRQRTNSIGHNPPHWGAERPFYNHLGGNQVSKEMKRMGFEDPKDKNAQESANPEDEVDEF LGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFLFICFVQ ITIVPHSLFMLSFYLSCFLLLALVVFISVIYACVKLFPTPLQTLSRKIVRSKKNSTLVGV FTITLVFLSAFVNMFMCNSKNLVGCLAEEHNITVNQVNACHVMESAFNYSLGDEQGFCGS PQSNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLIVEVPGVTLFDNAD LLVTANAIDFSNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTARLDFLWK LQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIAN FSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDST YDKAGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIW GNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPP LS NT seq 3789 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgctgcacagacagcagcgtcgccc gcgccccggggaggcccggagcatcgcgccgcgtggggagaagccgattcccgcgccaat ggctacccccacgcccccgggggatcgacccgcggctccaccaagcgatctgggggagcg gtgaccccacaacagcagcagcgcctggctagccgttggcgcggtggcgacgacgatgaa gaccctccactaagcggtgacgaccctctggtcggaggcttcggcttcagcttccgttct aagtcggcctggcaggagcgcggcggcgacgacggcggtcgcggcagcaggcggcagcgg cggggcgcggctggagggggcagcacccgggcgccccctgcgggcggcagtggcagttcg gcggcggccgcagcagccgcaggtggcacggaggtgcgcccccgctcggtggaggtgggc ctggaggagcgtcgaggaaaaggccgagcggccgaggagctggagcccggaactggcacc gtcgaggatggagacgggtccgaggatggaggcagttccgtggcgtcaggctctgggacc ggcacggtgctgtcgttgggcgcctgctgcctggccttgctgcagatattccgctctaag aagttcccgtcggacaaactggagcgtctgtaccagcgctatttcttccgcctgaaccag agcagcctcaccatgctcatggccgtgctggtgctcgtgtgcctggtcatgctcgctttc cacgcggcacggcccccgctccaggtagtctacctggccgtgttggcagctgctgtgggc gtgatccttatcatggctgtgctctgcaaccgtgcagccttccaccaggaccacatgggc ctggcctgctatgcgctcattgcagtggtgctggccgtccaggtagtgggcctgttgctg ccacagccacgcagcgcctccgagggcatctggtggaccgtgttcttcatctataccatc tacaccctgctgcctgtgcgcatgagggctgcggtgctcagcggggtgcttctgtcggct ctccacttggccatctctctgcacaccaacgcccaggaccagtttctgctgaaacagctt gtctccaacgtcctcatcttctcttgcaccaacatcgtgggtgtgtgcactcactaccca gccgaggtctcccagagacaagccttccaggagacccgggagtgcatccaagctcggctc cactcacagcgggagaaccagcaacaggagcgtctcctgctgtctgtccttccccgtcat gttgccatggagatgaaagcagacatcaacgccaaacaggaggatatgatgttccacaag atttacatccagaaacatgacaatgtgagcatcctgtttgctgacatcgaaggcttcact agcctggcatcccagtgtactgcccaagaactggtcatgaccctcaacgagctcttcgcc cgctttgacaagttggctgcggagaatcactgcttacggattaagatcctcggggattgt tactactgtgtctcggggctgcctgaagccagagctgaccacgcccactgctgcgtagag atgggaatggacatgatcgaggccatctcgtcggtccgggaggtgacaggggtgaacgtg aacatgcgtgtgggaattcacagcgggagagtacactgcggtgtccttggcctcagaaag tggcaattcgacgtgtggtctaacgatgtcacactggccaaccacatggaagctggcggc aaggcaggccgcatccacatcaccaaggccacactcaactacctgaacggggactatgag gtggagccaggctgtggtggtgagcgcaatgcctacctcaaggagcacagcatcgagacc ttcctcatcctgcgctgtacccagaagcggaaagaagagaaggccatgatcgccaagatg aaccgccagagaaccaactccattggacacaatccgcctcactggggagctgagcgcccc ttctacaaccacttgggtggcaaccaggtgtccaaggaaatgaagaggatgggctttgag gaccccaaggacaagaatgcccaggaaagtgccaaccctgaggatgaagtggacgagttt ctgggtcgagccatcgatgccaggagtattgacagactgcgatccgaacacgtccgaaag ttcctcttgacctttagggagcccgacttagagaagaagtactccaagcaggtggatgac cgatttggtgcctatgtggcctgtgcctcgcttgttttcctcttcatctgctttgtccag atcaccattgtgccccactccctgttcatgctgagcttctacctgtcgtgtttcctgcta ctggccttggtggtgtttatatctgtgatctacgcctgtgtgaagctcttccctactccc ctgcagacactctccaggaagatagtgcgatccaagaagaacagcaccctggtcggggtg ttcaccatcaccctggtgttcctctcggcttttgtcaacatgttcatgtgcaactctaag aacctggtgggttgcctggcagaggagcacaacatcacggtgaaccaggtgaacgcatgt catgtgatggagtcggccttcaactacagcctgggcgacgagcagggcttctgtggcagc ccccagtccaactgcaacttcccagagtacttcacctacagcgtgctgctcagcctgctg gcctgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatc gagctcatctacgtgctcatcgtagaggtgcccggtgtcacactctttgacaacgctgac cttctggtcaccgccaatgccatagacttcagcaacaacgggacctcccagtgccctgag catgcgaccaaggtggcgctgaaggtggtgacgcccatcatcatctctgtcttcgtgctg gctctgtatctgcatgctcagcaggtggaatccactgctcgccttgacttcctctggaaa ctgcaggccacagaagagaaggaggagatggaggagctgcaggcctacaaccggcgcttg ctgcacaacattctgcccaaggacgtggctgcccacttcctggcccgggagcggcgcaat gatgaactgtactaccaatcctgcgagtgcgtggctgtcatgtttgcctccatcgccaac ttctccgaattctacgtggagctagaggccaacaatgagggcgttgaatgcctacggctg ctcaatgagatcatcgcagactttgatgagatcatcagtgaggatcggttcaggcagctg gaaaagatcaagaccataggtagcacctacatggctgcctctggcctcaacgactccacc tatgacaaggcaggcaagacccacatcaaggctcttgcagacttcgccatgaagctgatg gaccaaatgaagtacatcaatgagcactccttcaacaacttccagatgaagatcgggctt aacattggacctgtagtggctggggtcattggggctcgcaagcctcagtatgacatctgg ggcaatacagtaaatgtggccagccgtatggacagcactggggtgcctgaccgcatccag gttactacagatatgtaccaggtgctggccgccaacacataccagctggagtgccggggt gtggtcaaggtcaagggcaagggtgagatgatgacctacttcctcaatggagggcctccc ctcagttag

Rattus norvegicus (rat): 81636 Help Entry 81636             CDS       T01003                                  Gene name Adcy2, AC2 Definition (RefSeq) adenylate cyclase 2   KO K08042   adenylate cyclase 2 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04922   Glucagon signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     81636 (Adcy2)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     81636 (Adcy2)    04371 Apelin signaling pathway     81636 (Adcy2)    04020 Calcium signaling pathway     81636 (Adcy2)    04072 Phospholipase D signaling pathway     81636 (Adcy2)    04024 cAMP signaling pathway     81636 (Adcy2)    04022 cGMP-PKG signaling pathway     81636 (Adcy2)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     81636 (Adcy2)   09144 Cellular community - eukaryotes    04540 Gap junction     81636 (Adcy2)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     81636 (Adcy2)    04062 Chemokine signaling pathway     81636 (Adcy2)   09152 Endocrine system    04911 Insulin secretion     81636 (Adcy2)    04922 Glucagon signaling pathway     81636 (Adcy2)    04923 Regulation of lipolysis in adipocytes     81636 (Adcy2)    04912 GnRH signaling pathway     81636 (Adcy2)    04913 Ovarian steroidogenesis     81636 (Adcy2)    04915 Estrogen signaling pathway     81636 (Adcy2)    04914 Progesterone-mediated oocyte maturation     81636 (Adcy2)    04921 Oxytocin signaling pathway     81636 (Adcy2)    04926 Relaxin signaling pathway     81636 (Adcy2)    04935 Growth hormone synthesis, secretion and action     81636 (Adcy2)    04918 Thyroid hormone synthesis     81636 (Adcy2)    04928 Parathyroid hormone synthesis, secretion and action     81636 (Adcy2)    04916 Melanogenesis     81636 (Adcy2)    04925 Aldosterone synthesis and secretion     81636 (Adcy2)    04927 Cortisol synthesis and secretion     81636 (Adcy2)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     81636 (Adcy2)    04270 Vascular smooth muscle contraction     81636 (Adcy2)   09154 Digestive system    04970 Salivary secretion     81636 (Adcy2)    04971 Gastric acid secretion     81636 (Adcy2)    04972 Pancreatic secretion     81636 (Adcy2)    04976 Bile secretion     81636 (Adcy2)   09156 Nervous system    04724 Glutamatergic synapse     81636 (Adcy2)    04727 GABAergic synapse     81636 (Adcy2)    04725 Cholinergic synapse     81636 (Adcy2)    04723 Retrograde endocannabinoid signaling     81636 (Adcy2)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     81636 (Adcy2)   09149 Aging    04211 Longevity regulating pathway     81636 (Adcy2)    04213 Longevity regulating pathway - multiple species     81636 (Adcy2)   09159 Environmental adaptation    04713 Circadian entrainment     81636 (Adcy2)    04714 Thermogenesis     81636 (Adcy2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     81636 (Adcy2)   09165 Substance dependence    05032 Morphine addiction     81636 (Adcy2)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     81636 (Adcy2)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     81636 (Adcy2)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     81636 (Adcy2)    05163 Human cytomegalovirus infection     81636 (Adcy2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     81636 (Adcy2) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      81636 (Adcy2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N HNOBA DUF349 Motif Other DBs NCBI-GeneID:  81636 NCBI-ProteinID:  NP_112269 RGD:  619965 Ensembl:  ENSRNOG00000032150 UniProt:  P26769 LinkDB All DBs Structure PDB:  1AB8 1AZS 1CUL 1CS4 3C14 3C15 1TL7 1CJT 1CJU 3C16 2GVD 1U0H 3MAA 1CJV 1CJK 3G82 2GVZ Thumbnails Position 1p11 AA seq 1090 aa AA seqDB search MRRRRYLRDRAEAAAAAAAGGGEGLQRSRDWLYESYYCMSQQHPLIVFLLLIVMGACLAL LAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRVFSLVIWICLVAMG YLFMCFGGTVSAWDQVSFFLFIIFVVYTMLPFNMRDAIIASILTSSSHTIVLSVYLSATP GAKEHLFWQILANVIIFICGNLAGAYHKHLMELALQQTYRDTCNCIKSRIKLEFEKRQQE RLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTR LASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKM GLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGV PGRVHISSVTLEHLNGAYKVEEGDGEIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRH TLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLR TKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKNIEKEYRATALPAFK YYVTCACLIFLCIFIVQILVLPKTSILGFSFGAAFLSLIFILFVCFAGQLLQCSKKASTS LMWLLKSSGIIANRPWPRISLTIVTTAIILTMAVFNMFFLSNSEETTLPTANTSNANVSV PDNQASILHARNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHTH AHVLDAYSQVLFQRPGIWKDLKTMGSVSLSIFFITLLVLGRQSEYYCRLDFLWKNKFKKE REEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYT ESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAIPSQEHAQ EPERQYMHIGTMVEFAYALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIW GNTVNVASRMDSTGVLDKIQVTEETSLILQTLGYTCTCRGIINVKGKGDLKTYFVNTEMS RSLSQSNLAS NT seq 3273 nt NT seq  +upstreamnt  +downstreamnt atgcggcggcgccgctacctgcgggaccgcgccgaggcggcggcggcagcggcggcggga ggcggagaggggctgcagcggtcccgggactggctctacgagtcctactactgcatgagc cagcagcacccgctcatcgtcttcctgctgctcatcgtcatgggcgcctgcctcgccctg ctagccgtcttcttcgcgctcgggctggaggtggaagaccatgtggcatttttaataacg gttcccactgccctggccattttctttgccatattcattcttgtctgcatagagtctgtg ttcaagaagctactccgtgtgttttcgctggtgatttggatatgtctggttgccatggga tacctgttcatgtgcttcggagggactgtgtctgcctgggaccaggtgtcattcttcctc ttcatcatctttgtggtatataccatgcttcccttcaacatgcgagatgccatcattgcc agcatcctcacatcttcatctcatacgatagtgctgagcgtctacctgtctgcaacacca ggggccaaggagcacctgttctggcagatactggccaatgtgatcattttcatttgtggg aacttggcgggagcctaccacaagcacctcatggagcttgccttgcagcaaacctatcgg gacacgtgtaattgcatcaagtcccggatcaagctggaatttgaaaaacggcagcaggaa cggctcctgctctccttgctgccagctcacatcgccatggagatgaaagctgaaatcatt cagaggctgcagggccccaaagcaggacagatggaaaacacaaacaacttccacaatctg tatgtcaaacgacacaccaacgtgagcatattatacgctgacattgttggcttcacccgc cttgcaagcgattgctcccctggcgaactggtccacatgctgaatgaactctttgggaag tttgatcaaatagcaaaggagaatgaatgcatgagaattaaaattttaggagactgctat tactgtgtttccgggctccctatatcactccctaaccatgccaagaactgtgtgaaaatg ggattggatatgtgcgaagccataaagaaagtgagggatgctaccggagttgatatcaac atgcgtgtaggagtgcattctgggaacgttctctgtggtgtgattggtctccagaagtgg cagtatgatgtgtggtctcatgatgttactctggcaaaccacatggaagctggaggagtc cctgggcgtgttcacatttcttcagtcactctggagcacttgaatggggcttataaagtg gaggaaggagatggtgagataagagacccatatttaaagcagcacttggtgaaaacctac tttgtaatcaatcccaagggagagcgacggagtcctcagcatctcttcagacctcgacac actctggacggagccaagatgagagcatctgtccgcatgacccggtacttggagtcctgg ggagcagccaagccattcgcacatctgcaccacagagatagcatgaccacagagaatggg aagattagtaccacggatgtgccaatgggtcaacataattttcaaaatcgcaccttaaga actaagtcacagaagaagagatttgaagaagaactgaatgaaaggatgatccaagcaatt gatgggatcaatgcacagaagcaatggctcaagtcagaagacattcaaagaatctccctg cttttctataacaagaatatagagaaagaataccgagctactgcactgccagcattcaag tactacgtgacctgtgcctgcctcatctttctctgcatcttcattgtacagatacttgta ttgccaaaaacgtccatccttggcttctcctttggagctgcatttctctccctcatcttc atcctctttgtctgcttcgctggacagcttttgcaatgcagcaaaaaggcctccacctct ctcatgtggcttttgaaatcatcaggcatcatcgccaaccgcccatggccacggatctcc ctcacaatcgtcaccacggctatcatactaaccatggctgtgttcaacatgtttttcctg agcaactctgaggagacaacccttcccactgccaatacatcaaatgcaaacgtttctgtc ccggataaccaggcgtcgattcttcatgctcgaaacttgtttttcctcccgtacttcata tacagctgcatcctgggcttgatctcctgctccgttttcctgagggtgaactatgagtta aaaatgttaatcatgatggtggcactcgtgggctacaacaccattctactccacacccat gcccatgttctggatgcgtacagccaggtcctgtttcagagaccaggcatttggaaagac ctgaagaccatgggctccgtgtcactctccatattcttcatcacgctgctggttctgggc agacagagtgaatattactgtaggttagacttcttgtggaagaacaagttcaaaaaagag cgggaggagatagaaaccatggagaacctaaatcgagtgctgctggagaacgtgcttcct gcacacgtggctgaacacttcctggccaggagcctgaaaaatgaggagctgtaccaccag tcctacgactgtgtctgtgtcatgtttgcctccattccggacttcaaggagttctacaca gagtcagatgtgaacaaggaaggcttggaatgcctgcggctcctgaatgagatcattgct gactttgatgatctgctttctaagccaaagttcagtggtgttgaaaagatcaagaccatt gggagcacatacatggcagccacgggactgagtgccatacccagccaggagcacgcccag gaacctgagcgtcagtacatgcacataggcaccatggtggagtttgcatatgccctggtg ggaaaactggatgccatcaataagcactccttcaacgacttcaaactgcgagtgggtatc aaccatgggcctgtaatagctggcgtcataggggctcaaaagccacagtatgacatctgg ggcaacactgtcaacgtggccagcagaatggacagcaccggggtcctggacaaaatacag gtgactgaggagacaagcctcatcttgcagacgcttggctacacgtgtacatgtcgaggt atcatcaatgtgaaggggaaaggggacctgaagacatattttgtaaacacagagatgtca aggtccctttctcagagcaacttggcatcctga

Rattus norvegicus (rat): 84420 Help Entry 84420             CDS       T01003                                  Gene name Adcy7 Definition (RefSeq) adenylate cyclase 7   KO K08047   adenylate cyclase 7 [EC:4.6.1.1] Organism rno  Rattus norvegicus (rat) Pathway rno00230   Purine metabolism rno01100   Metabolic pathways rno01522   Endocrine resistance rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04022   cGMP-PKG signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04072   Phospholipase D signaling pathway rno04114   Oocyte meiosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04371   Apelin signaling pathway rno04540   Gap junction rno04611   Platelet activation rno04713   Circadian entrainment rno04714   Thermogenesis rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04727   GABAergic synapse rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04914   Progesterone-mediated oocyte maturation rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04921   Oxytocin signaling pathway rno04923   Regulation of lipolysis in adipocytes rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04927   Cortisol synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04976   Bile secretion rno05032   Morphine addiction rno05163   Human cytomegalovirus infection rno05166   Human T-cell leukemia virus 1 infection rno05200   Pathways in cancer rno05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     84420 (Adcy7)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     84420 (Adcy7)    04371 Apelin signaling pathway     84420 (Adcy7)    04020 Calcium signaling pathway     84420 (Adcy7)    04072 Phospholipase D signaling pathway     84420 (Adcy7)    04024 cAMP signaling pathway     84420 (Adcy7)    04022 cGMP-PKG signaling pathway     84420 (Adcy7)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     84420 (Adcy7)   09144 Cellular community - eukaryotes    04540 Gap junction     84420 (Adcy7)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     84420 (Adcy7)    04062 Chemokine signaling pathway     84420 (Adcy7)   09152 Endocrine system    04911 Insulin secretion     84420 (Adcy7)    04923 Regulation of lipolysis in adipocytes     84420 (Adcy7)    04912 GnRH signaling pathway     84420 (Adcy7)    04913 Ovarian steroidogenesis     84420 (Adcy7)    04915 Estrogen signaling pathway     84420 (Adcy7)    04914 Progesterone-mediated oocyte maturation     84420 (Adcy7)    04921 Oxytocin signaling pathway     84420 (Adcy7)    04926 Relaxin signaling pathway     84420 (Adcy7)    04935 Growth hormone synthesis, secretion and action     84420 (Adcy7)    04918 Thyroid hormone synthesis     84420 (Adcy7)    04928 Parathyroid hormone synthesis, secretion and action     84420 (Adcy7)    04916 Melanogenesis     84420 (Adcy7)    04925 Aldosterone synthesis and secretion     84420 (Adcy7)    04927 Cortisol synthesis and secretion     84420 (Adcy7)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     84420 (Adcy7)    04270 Vascular smooth muscle contraction     84420 (Adcy7)   09154 Digestive system    04970 Salivary secretion     84420 (Adcy7)    04971 Gastric acid secretion     84420 (Adcy7)    04972 Pancreatic secretion     84420 (Adcy7)    04976 Bile secretion     84420 (Adcy7)   09156 Nervous system    04724 Glutamatergic synapse     84420 (Adcy7)    04727 GABAergic synapse     84420 (Adcy7)    04725 Cholinergic synapse     84420 (Adcy7)    04723 Retrograde endocannabinoid signaling     84420 (Adcy7)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     84420 (Adcy7)   09149 Aging    04211 Longevity regulating pathway     84420 (Adcy7)    04213 Longevity regulating pathway - multiple species     84420 (Adcy7)   09159 Environmental adaptation    04713 Circadian entrainment     84420 (Adcy7)    04714 Thermogenesis     84420 (Adcy7)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     84420 (Adcy7)   09165 Substance dependence    05032 Morphine addiction     84420 (Adcy7)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     84420 (Adcy7)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     84420 (Adcy7)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     84420 (Adcy7)    05163 Human cytomegalovirus infection     84420 (Adcy7)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     84420 (Adcy7) Enzymes [BR:rno01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      84420 (Adcy7) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc DUF1053 AC_N Motif Other DBs NCBI-GeneID:  84420 NCBI-ProteinID:  NP_445848 RGD:  619966 Ensembl:  ENSRNOG00000014776 UniProt:  F1LQT1 LinkDB All DBs Position 19p11 AA seq 1100 aa AA seqDB search MPAKGRYFLNEGDEGPKQAALYEKYRLTSQHGPLLLLLLLVAVATCIALVSIVFSHEDLR RHQAVLGTAFFMLTLFVALYVLVYVECLAQRWLRVLALLTWACLMILGSVLMWDSLENEA YAWEQVPFFLFIVFVVYVLLPLSTRAAIAVGVASTISHLLVFGAVTRAFKTSMSSTQLGL QLLANAVILLGGNFTGAFHKHQLQDASRDLFIYTVKCIQIRRKLRVEKRQQENLLLSVLP AHISMGMKLAIIERLKEGGDRHYTPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPK ELVVVLNELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAI KQVREATGVDISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITE ATLNHLDKAYEVEDGHGEQRDPYLKEMNIRTYLVIDPRSQQPPLPSHHLSKPKGDATLKM RASVRVTRYLESWGAARPFAHLNHRESVSSSEIPIPNGRRQKAIPLRRHRAPDRSASPKG RLEDDCDDEMLSAIEGLSSTRPCCSKSDDFHTFGPIFLEKGFEREYRLVPIPRARYDFAC ASLVFVCILLVHLLVMPRMATLGLSFGLVACLLGLVLSFCFATEFSRCLPARSTLQAISE SVETQPLLRLSLVVVTVGSLLTVAIINMPLTFNPGPEQPGDNETSPLAARNRVGTPCELL PYYTCSCVLGFIACSVFLRMSLELKAMLLTVALVAYLLLFNLSPCWQVSGNSTETNSTHR TRRLLSAEQSMNSHTLALGAQMTAPSPSSCLERDLKTMINFYLVLFYATLILLSRQIDYY CRLDCLWKKKFKKEHEEFETMENVNRLLLENVLPAHVAAHFIGDKAAEDWYHQSYDCVCV MFASVPDFKVFYTECDVNKEGLECLRLLNEIIADFDELLLKPKFSGVEKIKTIGSTYMAA AGLSVPSGHENQDLERKHVHIGVLVEFSMALMSKLDGINRHSFNSFRLRVGINHGPVIAG VIGARKPQYDIWGNTVNVASRMESTGELGKIQVTEETCTILQGLGYSCECRGLINVKGKG ELRTYFVCTDTAKFQGLGLN NT seq 3303 nt NT seq  +upstreamnt  +downstreamnt atgccagccaaggggcgctacttcctaaatgagggtgacgaaggccccaagcaggcagcg ctctatgagaagtacaggctcaccagccagcacgggccactgctgctcctgctcctcctg gtggctgtggccacctgcatcgccctcgtcagcatcgtcttcagccatgaggatctccgc agacaccaggctgtcctgggcactgcgttcttcatgctgacgctgtttgtggctctctat gtgctggtgtatgttgagtgcctagcacagcgatggctgcgcgtcttggctctactcacc tgggcttgcctcatgatactaggctccgtgctgatgtgggactccttggagaatgaagcc tatgcgtgggagcaggtgcctttcttcctgttcatcgtctttgtggtgtacgtactgttg cctctcagcacgagggcagctatcgcggtgggcgtagcctccaccatctcccatctcctg gtgtttggagctgtgacaagagccttcaagacatccatgtccagcacacagctggggctg cagctcctggccaatgccgttatccttctgggtgggaacttcaccggtgccttccacaag caccagcttcaggacgcttcgagggatctcttcatctacaccgtcaagtgtatccagatc cgccggaagcttcgcgtggagaagcgccagcaggagaacctgctgctttcagtgctccca gctcacatctccatgggtatgaagctggccatcattgaacgcctcaaagagggtggtgac cgccactacacgcctgacaacaactttcacagcctctatgtcaagcggcaccagaacgtc agcatcttgtatgcagacatcgtgggtttcacgaggctggccagcgactgctctcccaag gagctagtggtggtgctcaacgagctgtttgggaagtttgaccagattgccaaggccaac gagtgcatgcggatcaagatcctgggtgactgctactactgcgtgtcaggcctgcctgtg tcgctgcccacgcacgcccgcaactgtgtgaagatgggtctggacatatgtgaggccatt aagcaggtgcgtgaggccaccggagtggacatcagcatgcgtgtgggcattcactctggg aatgtcctgtgtggggtcatcgggctccgcaagtggcagtatgacgtgtggtcccatgac gtgtccctggccaacaggatggaggcagctggagtccctggccgggtgcacatcacagag gcgacactgaatcacctggacaaggcatacgaggtggaggacgggcacggggagcagcgc gacccctatctgaaagagatgaacatccgtacctacttggtgattgacccccggagtcag cagccgcccctacccagccaccacctgtccaagcccaagggggatgcaactctgaagatg cgggcttccgtgcgtgtaacccgctatctggagtcctggggggcagcgcggccctttgca cacctcaaccaccgggagagcgtgagcagcagtgagatccccatccccaacggacggagg cagaaggccattcctctgcgtcgacaccgtgcccctgataggagtgcatcccccaaggga cgcctggaagatgactgtgatgacgagatgctgtcagccattgaggggctcagctccacc aggccctgctgctccaagtctgatgacttccacacctttggtcccatcttcctggagaag ggctttgagcgtgagtaccgcctggtgcccatcccccgggctcgctatgacttcgcctgt gccagccttgtcttcgtctgcatcctgcttgtccacctcctagtgatgcccaggatggca actctgggcttgtcctttgggctggtggcctgcctgctggggctggttctaagcttctgc tttgctactgagttctcgaggtgccttccagcccgaagtacactccaggccatctcggag agtgtggagacacagcccctgctcagactttccctggttgtggtgactgttggcagctta ctgactgttgccatcatcaacatgccactgacatttaacccaggcccagagcagcctgga gacaatgagacaagcccactggctgcaaggaacagagttgggaccccatgtgaactcctc ccgtactacacctgcagctgcgtcctgggcttcattgcatgctctgttttcctgcggatg agcctggaactgaaggccatgttgctgacggtggccttggtggcctacctgctgctcttc aacctctccccatgctggcaggtctcaggcaacagcacagagaccaacagcacacacagg acacgtcggctcctgtctgcagaacaaagcatgaacagccacacccttgctctgggggct cagatgactgccccctcccccagcagttgtttagagagagacctgaagaccatgatcaac ttctacctggtcctgttctatgccaccctcatcttgctgtctagacagattgactattac tgccgcttggactgtctgtggaagaagaagtttaagaaggagcatgaggagtttgaaaca atggagaatgtgaaccgcctcctcctagagaatgttctgccagcacatgtggctgcccac ttcatcggtgacaaggcagctgaggactggtaccatcaatcttatgactgtgtctgtgtc atgtttgcatccgttccggacttcaaagtgttctatactgagtgtgatgtcaacaaagaa ggattggagtgccttcgcctgctgaatgagatcattgctgattttgacgagctgctgctg aagcccaagttcagtggtgtggagaagatcaagaccattggcagcacctacatggctgct gcagggctcagtgtcccctcaggacatgagaaccaggacctggagcggaagcatgtgcac attggtgtcttggtggagtttagcatggccctgatgagcaagctggatggaatcaacagg cactccttcaactccttccgcctccgagttggcataaaccacggccctgtgattgctgga gtgattggcgcacgcaagcctcagtatgacatctggggaaacacagtcaatgttgccagc cgcatggagagcaccggagagcttgggaagatccaggttaccgaggagacgtgcaccatc ctccagggactgggatattcttgtgagtgccgtgggctcatcaacgtcaaaggcaaaggg gagctgcggacttactttgtttgtacagacactgccaagtttcaagggctggggctaaac tga

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