Rattus norvegicus (rat): 25391
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Entry
25391 CDS
T01003
Symbol
Atp2a3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04020
Calcium signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04148
Efferocytosis
rno04260
Cardiac muscle contraction
rno04261
Adrenergic signaling in cardiomyocytes
rno04380
Osteoclast differentiation
rno04919
Thyroid hormone signaling pathway
rno04972
Pancreatic secretion
rno05010
Alzheimer disease
rno05017
Spinocerebellar ataxia
rno05022
Pathways of neurodegeneration - multiple diseases
rno05410
Hypertrophic cardiomyopathy
rno05412
Arrhythmogenic right ventricular cardiomyopathy
rno05414
Dilated cardiomyopathy
rno05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
25391 (Atp2a3)
04024 cAMP signaling pathway
25391 (Atp2a3)
04022 cGMP-PKG signaling pathway
25391 (Atp2a3)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
25391 (Atp2a3)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
25391 (Atp2a3)
09153 Circulatory system
04260 Cardiac muscle contraction
25391 (Atp2a3)
04261 Adrenergic signaling in cardiomyocytes
25391 (Atp2a3)
09154 Digestive system
04972 Pancreatic secretion
25391 (Atp2a3)
09158 Development and regeneration
04380 Osteoclast differentiation
25391 (Atp2a3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
25391 (Atp2a3)
05017 Spinocerebellar ataxia
25391 (Atp2a3)
05022 Pathways of neurodegeneration - multiple diseases
25391 (Atp2a3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
25391 (Atp2a3)
05412 Arrhythmogenic right ventricular cardiomyopathy
25391 (Atp2a3)
05414 Dilated cardiomyopathy
25391 (Atp2a3)
05415 Diabetic cardiomyopathy
25391 (Atp2a3)
Enzymes [BR:
rno01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
25391 (Atp2a3)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
DUF3106
Motif
Other DBs
NCBI-GeneID:
25391
NCBI-ProteinID:
NP_037046
RGD:
2175
Ensembl:
ENSRNOG00000017912
UniProt:
P18596
LinkDB
All DBs
Position
10:58079710..58111279
Genome browser
AA seq
999 aa
AA seq
DB search
MEEAHLLSAADVLRRFSVTAEGGLTLEQVTDARERYGPNELPTEEGKSLWELVVEQFEDL
LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTDAIPDPRAVNQDKKNMLFSGTNIASGKALGVAVATGLHTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEAEAGACRLHEFTISGTTYTPEGEVRQGEQLVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLKGLSRVERAGACNSVIKQLMQ
KEFTLEFSRDRKSMSVYCTPTRADPKAQGSKMFVKGAPESVIERCSSVRVGSRTVPLSAT
SREHILAKIRDWGSGSHTLRCLALATRDTPPRKEDMQLDDCSQFVQYETGLTFVGCVGML
DPPRPEVAACITRCSRAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVLGKAYTGREFDD
LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRNPREALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDAEGPQVTFHQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLGAVVMSMALHFLILLVPPLPLIFQVT
PLSGRQWGVVLQMSLPVILLDEALKYLSRHHVDEKKDLK
NT seq
3000 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggcgcacctgctctcggctgccgacgtgctgcgtcgcttctcggtgacagcc
gagggcggcttgaccctggagcaggtgaccgacgcccgggagcgatacggccccaacgaa
ctccctactgaggaagggaaatccctgtgggagctggtggtggagcagtttgaggacctc
ttggtgcgcatcctgctgctggcagccctggtttcctttgtcctggcctggtttgaggag
ggtgaggagaccacgacggccttcgtggagcccctcgtcatcatgttaatccttgtggcc
aatgcgatcgtgggagtgtggcaggaacgcaatgctgagagtgccattgaggccttgaag
gagtatgagcctgagatgggtaaggtgatccgctctgaccgcaagggtgtgcagaggatc
cgagccagggacatcgtccctggggacattgtggaagtggcagtgggagacaaggtacct
gctgacctccgcctcatcgagatcaagtccaccacacttcgagtggaccagtccatcctg
acaggggaatccgtgtctgtgactaagcacacagatgccattccagacccccgagccgtg
aaccaggacaagaagaacatgctgttttctggcaccaatattgcatcaggcaaagccctg
ggtgtggctgtggccacaggcttgcacacagagctgggcaagattcggagccagatggcg
gctgtggagcctgagcggacgccactgcagcgcaagctggatgaatttgggaggcagctg
tcccatgccatctctgtgatctgtgtggctgtgtgggtcatcaacatcggacactttgct
gacccggcccatggtggatcctggctccgtggggcagtctactacttcaagattgctgtg
gccctggctgtggctgctatccccgagggcctcccagcagtcatcactacatgcctagca
ctgggcacaagacgtatggcacgtaagaacgccattgtgcggagcctgccctctgtggag
accctgggctgcacctcagtcatctgctctgacaagacagggacactcaccaccaatcaa
atgtctgtctgcaggatgttcgtggtagctgaagcagaggcaggcgcctgtcgtttacac
gaattcaccatttcgggtaccacgtataccccagagggcgaagtgaggcaaggggaacag
cttgtgcgctgtgggcagtttgatggacttgtggagctcgcaaccatctgtgcactctgc
aatgattctgcactggactacaatgaggccaagggtgtgtatgagaaggtaggagaggcc
acagagacagccctcacttgcctggtagagaagatgaacgtgtttgacacagacctgaaa
ggactgtcgcgggtcgagcgcgctggtgcctgcaattccgtcatcaagcaactcatgcag
aaggagttcaccctcgaattctcccgggaccggaagtccatgtctgtgtactgcacaccc
actcgtgctgaccccaaggcccagggcagcaagatgtttgtgaagggagctcctgagagt
gtaattgagcgctgcagctcagtccgcgtgggaagccgaacagtacccctaagcgccacc
tccagagagcatatcctggccaagatccgagactggggctcaggctctcatacattgcgc
tgcttagcactggccaccagggacacacccccaaggaaggaggacatgcaactggatgac
tgcagtcagtttgtacagtacgagacaggcctgaccttcgtgggctgcgtgggcatgtta
gacccaccgagaccagaggtggctgcctgtatcacacgctgttctcgggcgggcattcga
gtggtcatgatcacaggggacaacaaagggacagctgtggccatctgccgccgacttggc
atctttggggatacggaggatgtgttgggcaaggcttacacgggccgagaattcgatgac
ctcagcccagagcagcagcgccaggcttgccgtaccgcccgatgctttgcccgtgtggaa
cccgcacataagtctcgcatcgtggagaacctccagtcctttaatgagatcaccgccatg
actggcgatggggtgaatgatgcaccagccctgaagaaggcagagatcggcatcgccatg
ggctcaggcactgctgtggccaagtcggcagcggagatggttctgtctgatgacaacttt
gcctccattgtggctgcagtggaggagggcagggccatctacaacaacatgaagcaattc
atccgctacctcatctcctccaatgttggcgaggttgtctgcatcttcctcacagcaatt
ctgggcctgcccgaagccctgatccctgtgcagctgctctgggtgaacctggtaacagat
ggcttacctgccacagcccttggcttcaacccacccgatctggacatcatggaaaagctg
cctcggaacccccgggaggctctcatcagcggctggctttttttccgctatttggctatt
ggagtgtacgtaggcctggctacagtggctgccgccacctggtggttcctgtatgacgct
gagggaccacaagtcaccttccatcagctgaggaacttcctgaagtgctctgaagacaat
ccactgtttgccggcatcgactgcgaggtctttgagtcacgcttccccacgaccatggcc
ttatctgtgcttgtgaccattgaaatgtgcaacgcccttaacagcgtctcagagaaccag
tcactgctgcgtatgccaccctggctgaacccttggctgctgggggctgtggtcatgtcc
atggccctgcattttctcatccttttggtgccgcctctgcccctcattttccaggtgacc
ccactgagtggtcgacagtggggggtggtgcttcagatgtctctgcctgtcatcctgctt
gacgaggccctcaagtatctgtccaggcatcacgtggatgaaaaaaaggacctgaagtaa
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