Rattus norvegicus (rat): 84027 Help Entry 84027             CDS       T01003                                  Gene name Gsk3b Definition (RefSeq) glycogen synthase kinase 3 beta   KO K03083   glycogen synthase kinase 3 beta [EC:2.7.11.26] Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno04012   ErbB signaling pathway rno04062   Chemokine signaling pathway rno04110   Cell cycle rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04310   Wnt signaling pathway rno04340   Hedgehog signaling pathway rno04360   Axon guidance rno04390   Hippo signaling pathway rno04510   Focal adhesion rno04550   Signaling pathways regulating pluripotency of stem cells rno04657   IL-17 signaling pathway rno04660   T cell receptor signaling pathway rno04662   B cell receptor signaling pathway rno04722   Neurotrophin signaling pathway rno04728   Dopaminergic synapse rno04910   Insulin signaling pathway rno04916   Melanogenesis rno04917   Prolactin signaling pathway rno04919   Thyroid hormone signaling pathway rno04931   Insulin resistance rno04932   Non-alcoholic fatty liver disease rno04934   Cushing syndrome rno04935   Growth hormone synthesis, secretion and action rno05010   Alzheimer disease rno05020   Prion disease rno05022   Pathways of neurodegeneration - multiple diseases rno05135   Yersinia infection rno05160   Hepatitis C rno05162   Measles rno05163   Human cytomegalovirus infection rno05165   Human papillomavirus infection rno05167   Kaposi sarcoma-associated herpesvirus infection rno05200   Pathways in cancer rno05210   Colorectal cancer rno05213   Endometrial cancer rno05215   Prostate cancer rno05217   Basal cell carcinoma rno05224   Breast cancer rno05225   Hepatocellular carcinoma rno05226   Gastric cancer Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     84027 (Gsk3b)    04310 Wnt signaling pathway     84027 (Gsk3b)    04340 Hedgehog signaling pathway     84027 (Gsk3b)    04390 Hippo signaling pathway     84027 (Gsk3b)    04151 PI3K-Akt signaling pathway     84027 (Gsk3b)    04150 mTOR signaling pathway     84027 (Gsk3b)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     84027 (Gsk3b)   09144 Cellular community - eukaryotes    04510 Focal adhesion     84027 (Gsk3b)    04550 Signaling pathways regulating pluripotency of stem cells     84027 (Gsk3b)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     84027 (Gsk3b)    04657 IL-17 signaling pathway     84027 (Gsk3b)    04662 B cell receptor signaling pathway     84027 (Gsk3b)    04062 Chemokine signaling pathway     84027 (Gsk3b)   09152 Endocrine system    04910 Insulin signaling pathway     84027 (Gsk3b)    04917 Prolactin signaling pathway     84027 (Gsk3b)    04935 Growth hormone synthesis, secretion and action     84027 (Gsk3b)    04919 Thyroid hormone signaling pathway     84027 (Gsk3b)    04916 Melanogenesis     84027 (Gsk3b)   09156 Nervous system    04728 Dopaminergic synapse     84027 (Gsk3b)    04722 Neurotrophin signaling pathway     84027 (Gsk3b)   09158 Development and regeneration    04360 Axon guidance     84027 (Gsk3b)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     84027 (Gsk3b)   09162 Cancer: specific types    05210 Colorectal cancer     84027 (Gsk3b)    05225 Hepatocellular carcinoma     84027 (Gsk3b)    05226 Gastric cancer     84027 (Gsk3b)    05217 Basal cell carcinoma     84027 (Gsk3b)    05215 Prostate cancer     84027 (Gsk3b)    05213 Endometrial cancer     84027 (Gsk3b)    05224 Breast cancer     84027 (Gsk3b)   09164 Neurodegenerative disease    05010 Alzheimer disease     84027 (Gsk3b)    05020 Prion disease     84027 (Gsk3b)    05022 Pathways of neurodegeneration - multiple diseases     84027 (Gsk3b)   09167 Endocrine and metabolic disease    04932 Non-alcoholic fatty liver disease     84027 (Gsk3b)    04931 Insulin resistance     84027 (Gsk3b)    04934 Cushing syndrome     84027 (Gsk3b)   09171 Infectious disease: bacterial    05135 Yersinia infection     84027 (Gsk3b)   09172 Infectious disease: viral    05160 Hepatitis C     84027 (Gsk3b)    05162 Measles     84027 (Gsk3b)    05163 Human cytomegalovirus infection     84027 (Gsk3b)    05167 Kaposi sarcoma-associated herpesvirus infection     84027 (Gsk3b)    05165 Human papillomavirus infection     84027 (Gsk3b)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     84027 (Gsk3b)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     84027 (Gsk3b)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:rno03036]     84027 (Gsk3b) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.26  tau-protein kinase      84027 (Gsk3b) Protein kinases [BR:rno01001]  Serine/threonine kinases: CMGC group   GSK family [OT]    84027 (Gsk3b) Chromosome and associated proteins [BR:rno03036]  Eukaryotic type   Centrosome formation and ciliogenesis proteins    Kinases and associated factors     84027 (Gsk3b) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Kinase-like APH Kdo ABC1 Motif Other DBs NCBI-GeneID:  84027 NCBI-ProteinID:  NP_114469 RGD:  70982 Ensembl:  ENSRNOG00000002833 UniProt:  P18266 A0A0G2JSH4 LinkDB All DBs Position 11q21 AA seq 420 aa AA seqDB search MSGRPRTTSFAESCKPVQQPSAFGSMKVSRDKDGSKVTTVVATPGQGPDRPQEVSYTDTK VIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSG EKKDEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHR DIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDV WSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHP WTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALF NFTTQELSSNPPLATILIPPHARIQAAASPPANATAASDTNAGDRGQTNNAASASASNST NT seq 1263 nt NT seq  +upstreamnt  +downstreamnt atgtcggggcgaccgagaaccacctcctttgcggagagctgcaagccagtgcagcagcct tcagcttttggtagcatgaaagttagcagagataaagatggcagcaaggtaaccacagtg gtggcaactcctggacagggtcctgacaggccacaggaagtcagttacacagacactaaa gtcattggaaatgggtcatttggtgtggtatatcaagccaaactttgtgactcaggagaa ctggtggccatcaagaaagttcttcaggacaagcgatttaagaaccgagagctccagatc atgagaaagctagatcactgtaacatagtccgattgcggtatttcttctactcgagtggc gagaagaaagatgaggtctaccttaacctggtgctggactatgttccggaaacagtgtac agagtcgccagacactatagtcgagccaagcagacactccctgtgatctatgtcaagttg tatatgtaccagctgttcagaagtctagcctatatccattcctttgggatctgccatcga gacattaaaccacagaacctcttgctggatcctgatacagctgtattaaaactctgcgac tttggaagtgcaaagcagctggtccgaggagagcccaatgtttcatatatctgttctcgg tactacagggcaccagagctgatctttggagccaccgattacacgtctagtatagatgta tggtctgcaggctgtgtgttggctgaattgttgctaggacaaccaatatttcctggggac agtggtgtggatcagttggtggaaataataaaggtcctaggaacaccaacaagggagcaa attagagaaatgaacccaaattatacagaattcaaattcccccaaatcaaggcacatcct tggacgaaggtctttcggccccgaactccaccagaggcaatcgcactgtgtagccgtctc ctggagtacacgccgaccgcccggctaacaccactggaagcttgtgcacattcatttttt gatgaattacgggacccaaatgtcaaactaccaaatgggcgagacacacctgccctcttc aactttaccactcaagaactgtcaagtaacccacctctggccaccatccttatccctcct cacgctcggattcaggcagctgcttcaccgcctgcaaacgccacagcagcctcagatact aatgctggagaccgtggacagaccaataacgccgcttctgcatcagcctccaactctacc tga

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