Rhinopithecus roxellana (golden snub-nosed monkey): 104654600 Help Entry 104654600         CDS       T03989                                  Gene name HRAS Definition (RefSeq) GTPase HRas isoform X1   KO K02833   GTPase HRas Organism rro  Rhinopithecus roxellana (golden snub-nosed monkey) Pathway rro01521   EGFR tyrosine kinase inhibitor resistance rro01522   Endocrine resistance rro04010   MAPK signaling pathway rro04012   ErbB signaling pathway rro04014   Ras signaling pathway rro04015   Rap1 signaling pathway rro04062   Chemokine signaling pathway rro04068   FoxO signaling pathway rro04071   Sphingolipid signaling pathway rro04072   Phospholipase D signaling pathway rro04137   Mitophagy - animal rro04140   Autophagy - animal rro04144   Endocytosis rro04150   mTOR signaling pathway rro04151   PI3K-Akt signaling pathway rro04210   Apoptosis rro04211   Longevity regulating pathway rro04213   Longevity regulating pathway - multiple species rro04218   Cellular senescence rro04360   Axon guidance rro04370   VEGF signaling pathway rro04371   Apelin signaling pathway rro04510   Focal adhesion rro04540   Gap junction rro04550   Signaling pathways regulating pluripotency of stem cells rro04625   C-type lectin receptor signaling pathway rro04630   JAK-STAT signaling pathway rro04650   Natural killer cell mediated cytotoxicity rro04660   T cell receptor signaling pathway rro04662   B cell receptor signaling pathway rro04664   Fc epsilon RI signaling pathway rro04714   Thermogenesis rro04720   Long-term potentiation rro04722   Neurotrophin signaling pathway rro04725   Cholinergic synapse rro04726   Serotonergic synapse rro04730   Long-term depression rro04810   Regulation of actin cytoskeleton rro04910   Insulin signaling pathway rro04912   GnRH signaling pathway rro04915   Estrogen signaling pathway rro04916   Melanogenesis rro04917   Prolactin signaling pathway rro04919   Thyroid hormone signaling pathway rro04921   Oxytocin signaling pathway rro04926   Relaxin signaling pathway rro04929   GnRH secretion rro04933   AGE-RAGE signaling pathway in diabetic complications rro04935   Growth hormone synthesis, secretion and action rro05010   Alzheimer disease rro05022   Pathways of neurodegeneration - multiple diseases rro05034   Alcoholism rro05132   Salmonella infection rro05160   Hepatitis C rro05161   Hepatitis B rro05163   Human cytomegalovirus infection rro05165   Human papillomavirus infection rro05166   Human T-cell leukemia virus 1 infection rro05167   Kaposi sarcoma-associated herpesvirus infection rro05170   Human immunodeficiency virus 1 infection rro05200   Pathways in cancer rro05203   Viral carcinogenesis rro05205   Proteoglycans in cancer rro05206   MicroRNAs in cancer rro05210   Colorectal cancer rro05211   Renal cell carcinoma rro05213   Endometrial cancer rro05214   Glioma rro05215   Prostate cancer rro05216   Thyroid cancer rro05218   Melanoma rro05219   Bladder cancer rro05220   Chronic myeloid leukemia rro05221   Acute myeloid leukemia rro05223   Non-small cell lung cancer rro05224   Breast cancer rro05225   Hepatocellular carcinoma rro05226   Gastric cancer rro05230   Central carbon metabolism in cancer rro05231   Choline metabolism in cancer rro05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:rro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104654600 (HRAS)    04012 ErbB signaling pathway     104654600 (HRAS)    04014 Ras signaling pathway     104654600 (HRAS)    04015 Rap1 signaling pathway     104654600 (HRAS)    04370 VEGF signaling pathway     104654600 (HRAS)    04371 Apelin signaling pathway     104654600 (HRAS)    04630 JAK-STAT signaling pathway     104654600 (HRAS)    04068 FoxO signaling pathway     104654600 (HRAS)    04072 Phospholipase D signaling pathway     104654600 (HRAS)    04071 Sphingolipid signaling pathway     104654600 (HRAS)    04151 PI3K-Akt signaling pathway     104654600 (HRAS)    04150 mTOR signaling pathway     104654600 (HRAS)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     104654600 (HRAS)    04140 Autophagy - animal     104654600 (HRAS)    04137 Mitophagy - animal     104654600 (HRAS)   09143 Cell growth and death    04210 Apoptosis     104654600 (HRAS)    04218 Cellular senescence     104654600 (HRAS)   09144 Cellular community - eukaryotes    04510 Focal adhesion     104654600 (HRAS)    04540 Gap junction     104654600 (HRAS)    04550 Signaling pathways regulating pluripotency of stem cells     104654600 (HRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     104654600 (HRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     104654600 (HRAS)    04650 Natural killer cell mediated cytotoxicity     104654600 (HRAS)    04660 T cell receptor signaling pathway     104654600 (HRAS)    04662 B cell receptor signaling pathway     104654600 (HRAS)    04664 Fc epsilon RI signaling pathway     104654600 (HRAS)    04062 Chemokine signaling pathway     104654600 (HRAS)   09152 Endocrine system    04910 Insulin signaling pathway     104654600 (HRAS)    04929 GnRH secretion     104654600 (HRAS)    04912 GnRH signaling pathway     104654600 (HRAS)    04915 Estrogen signaling pathway     104654600 (HRAS)    04917 Prolactin signaling pathway     104654600 (HRAS)    04921 Oxytocin signaling pathway     104654600 (HRAS)    04926 Relaxin signaling pathway     104654600 (HRAS)    04935 Growth hormone synthesis, secretion and action     104654600 (HRAS)    04919 Thyroid hormone signaling pathway     104654600 (HRAS)    04916 Melanogenesis     104654600 (HRAS)   09156 Nervous system    04725 Cholinergic synapse     104654600 (HRAS)    04726 Serotonergic synapse     104654600 (HRAS)    04720 Long-term potentiation     104654600 (HRAS)    04730 Long-term depression     104654600 (HRAS)    04722 Neurotrophin signaling pathway     104654600 (HRAS)   09158 Development and regeneration    04360 Axon guidance     104654600 (HRAS)   09149 Aging    04211 Longevity regulating pathway     104654600 (HRAS)    04213 Longevity regulating pathway - multiple species     104654600 (HRAS)   09159 Environmental adaptation    04714 Thermogenesis     104654600 (HRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104654600 (HRAS)    05206 MicroRNAs in cancer     104654600 (HRAS)    05205 Proteoglycans in cancer     104654600 (HRAS)    05203 Viral carcinogenesis     104654600 (HRAS)    05230 Central carbon metabolism in cancer     104654600 (HRAS)    05231 Choline metabolism in cancer     104654600 (HRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     104654600 (HRAS)   09162 Cancer: specific types    05210 Colorectal cancer     104654600 (HRAS)    05225 Hepatocellular carcinoma     104654600 (HRAS)    05226 Gastric cancer     104654600 (HRAS)    05214 Glioma     104654600 (HRAS)    05216 Thyroid cancer     104654600 (HRAS)    05221 Acute myeloid leukemia     104654600 (HRAS)    05220 Chronic myeloid leukemia     104654600 (HRAS)    05218 Melanoma     104654600 (HRAS)    05211 Renal cell carcinoma     104654600 (HRAS)    05219 Bladder cancer     104654600 (HRAS)    05215 Prostate cancer     104654600 (HRAS)    05213 Endometrial cancer     104654600 (HRAS)    05224 Breast cancer     104654600 (HRAS)    05223 Non-small cell lung cancer     104654600 (HRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     104654600 (HRAS)    05022 Pathways of neurodegeneration - multiple diseases     104654600 (HRAS)   09165 Substance dependence    05034 Alcoholism     104654600 (HRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     104654600 (HRAS)   09171 Infectious disease: bacterial    05132 Salmonella infection     104654600 (HRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104654600 (HRAS)    05170 Human immunodeficiency virus 1 infection     104654600 (HRAS)    05161 Hepatitis B     104654600 (HRAS)    05160 Hepatitis C     104654600 (HRAS)    05163 Human cytomegalovirus infection     104654600 (HRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     104654600 (HRAS)    05165 Human papillomavirus infection     104654600 (HRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     104654600 (HRAS)    01522 Endocrine resistance     104654600 (HRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rro04131]     104654600 (HRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:rro04147]     104654600 (HRAS)    04031 GTP-binding proteins [BR:rro04031]     104654600 (HRAS) Membrane trafficking [BR:rro04131]  Endocytosis   Macropinocytosis    Ras GTPases     104654600 (HRAS) Exosome [BR:rro04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    104654600 (HRAS)   Exosomal proteins of colorectal cancer cells    104654600 (HRAS) GTP-binding proteins [BR:rro04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     104654600 (HRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Gtr1_RagA G-alpha ATP_bind_1 Septin Ldh_1_N AAA_25 AAA_16 Motif Other DBs NCBI-GeneID:  104654600 NCBI-ProteinID:  XP_030773857 LinkDB All DBs Position 15 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG CMSCKCVLS NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgacggaatataagctcgtggtggtgggcgccggcggtgtgggcaagagtgcgctgacc atccagctgatccagaaccacttcgtggacgaatacgaccccacgatagaggactcctat cggaagcaggtggtcattgatggggagacatgcctgttggacatcctggacacggccggc caagaggagtacagcgccatgcgggaccagtacatgcgcacgggggaaggcttcctgtgt gtgtttgccatcaacaacaccaagtcctttgaggacatccaccagtacagggagcagatc aagcgggtgaaggactcagacgacgtgcccatggtgctggtggggaacaagtgtgacctg gctgcacgcactgtggagtctcggcaggctcaggacctcgcccgaagctatggtatccct tacatcgagacctcggccaagacccgacagggagtggaggatgccttctacacgttggtg cgtgagattcggcagcataagctgcggaagctgaaccctcctgatgagagtggccccggc tgcatgagctgcaagtgtgtgctctcctga

Rhinopithecus roxellana (golden snub-nosed monkey): 104662303 Help Entry 104662303         CDS       T03989                                  Gene name MRAS Definition (RefSeq) ras-related protein M-Ras isoform X1   KO K07831   Ras-related protein M-Ras Organism rro  Rhinopithecus roxellana (golden snub-nosed monkey) Pathway rro04010   MAPK signaling pathway rro04014   Ras signaling pathway rro04015   Rap1 signaling pathway rro04072   Phospholipase D signaling pathway rro04137   Mitophagy - animal rro04140   Autophagy - animal rro04218   Cellular senescence rro04371   Apelin signaling pathway rro04625   C-type lectin receptor signaling pathway rro04810   Regulation of actin cytoskeleton rro05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:rro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104662303 (MRAS)    04014 Ras signaling pathway     104662303 (MRAS)    04015 Rap1 signaling pathway     104662303 (MRAS)    04371 Apelin signaling pathway     104662303 (MRAS)    04072 Phospholipase D signaling pathway     104662303 (MRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104662303 (MRAS)    04137 Mitophagy - animal     104662303 (MRAS)   09143 Cell growth and death    04218 Cellular senescence     104662303 (MRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     104662303 (MRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     104662303 (MRAS)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     104662303 (MRAS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:rro04031]     104662303 (MRAS) GTP-binding proteins [BR:rro04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     104662303 (MRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc GTP_EFTU Arf RsgA_GTPase MMR_HSR1 ATP_bind_1 AAA_16 MMR_HSR1_Xtn Gtr1_RagA Motif Other DBs NCBI-GeneID:  104662303 NCBI-ProteinID:  XP_010361607 UniProt:  A0A2K6P0U9 LinkDB All DBs Position 1 AA seq 208 aa AA seqDB search MATSAVPSDNLPTYKLVVVGDGGVGKSALTIQFFQKIFVPDYDPTIEDSYLKHTEIDNQW AILDVLDTAGQEEFSAMREQYMRTGDGFLIVYSVTDKASFEHVDRFHQLILRVKDRESFP MILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIP EKSQKKKKKTKWRGDRATGTHKLQCVIL NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atggcaaccagcgccgtccccagtgacaacctccccacatacaagctggtggtggtgggg gatgggggcgtgggcaaaagtgccctcaccatccagtttttccaaaagatctttgtgcct gactatgaccccaccattgaagactcctacctgaaacatacagagattgacaatcagtgg gccatcttggacgttctggacacagccgggcaggaggaattcagcgccatgcgggagcag tacatgcgcacgggagatggcttcctcatcgtctactccgtcaccgacaaggccagcttc gagcatgtggaccgtttccaccagctcatcctgcgcgtcaaagacagggagtcattcccg atgatcctcgtggccaacaaggtcgatttgatgcacttaaggaaaatcaccagggagcaa ggaaaagaaatggcgaccaaacacaatattccgtacatagaaaccagtgccaaggaccca cctctcaatgtcgacaaagccttccatgacctcgtgagagtaattaggcaacagattccg gaaaaaagccagaagaagaagaagaaaaccaaatggcggggagaccgggccacaggcacc cacaaactgcaatgtgtgatcttgtga

Rhinopithecus roxellana (golden snub-nosed monkey): 104667204 Help Entry 104667204         CDS       T03989                                  Gene name RRAS Definition (RefSeq) ras-related protein R-Ras isoform X1   KO K07829   Ras-related protein R-Ras Organism rro  Rhinopithecus roxellana (golden snub-nosed monkey) Pathway rro04010   MAPK signaling pathway rro04014   Ras signaling pathway rro04015   Rap1 signaling pathway rro04024   cAMP signaling pathway rro04072   Phospholipase D signaling pathway rro04137   Mitophagy - animal rro04140   Autophagy - animal rro04218   Cellular senescence rro04360   Axon guidance rro04371   Apelin signaling pathway rro04625   C-type lectin receptor signaling pathway rro04810   Regulation of actin cytoskeleton rro05132   Salmonella infection rro05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:rro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104667204 (RRAS)    04014 Ras signaling pathway     104667204 (RRAS)    04015 Rap1 signaling pathway     104667204 (RRAS)    04371 Apelin signaling pathway     104667204 (RRAS)    04072 Phospholipase D signaling pathway     104667204 (RRAS)    04024 cAMP signaling pathway     104667204 (RRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104667204 (RRAS)    04137 Mitophagy - animal     104667204 (RRAS)   09143 Cell growth and death    04218 Cellular senescence     104667204 (RRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     104667204 (RRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     104667204 (RRAS)   09158 Development and regeneration    04360 Axon guidance     104667204 (RRAS)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     104667204 (RRAS)   09171 Infectious disease: bacterial    05132 Salmonella infection     104667204 (RRAS)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:rro04031]     104667204 (RRAS) GTP-binding proteins [BR:rro04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     104667204 (RRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU ATP_bind_1 MMR_HSR1 AAA_22 Ribosomal_S30AE Motif Other DBs NCBI-GeneID:  104667204 NCBI-ProteinID:  XP_010367790 UniProt:  A0A2K6NKJ8 LinkDB All DBs Position 12 AA seq 218 aa AA seqDB search MSSGAASGTGRGRPRGGGPGPGDPPPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDP TIEDSYTKICSVDGIPARLDILDTAGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVG KLFTQILRVKDRDDFPVVLVGNKADLEAQRQVPRSEASAFGASHHVAYFEASAKLRLNVD EAFEQLVRAVRKYQEQELPPSPPSAPRKKGRGCPCVLL NT seq 657 nt NT seq  +upstreamnt  +downstreamnt atgagcagcggggcggcgtccgggacagggcgggggcggccccggggcgggggacctggg cccggggaccccccgcccagcgagacacacaagctggtggtcgtgggcggcggcggcgtg ggcaagagcgcgctgaccatccagttcatccagtcctacttcgtgtctgactacgacccc actattgaggactcctacacgaagatctgcagtgtggatggcatcccggcccggctggac atcctggacactgcgggccaggaggagttcggggccatgagagagcagtacatgcgtgcc ggccatggcttcctgctggtgtttgccattaatgaccggcagagtttcaacgaggtgggc aagctcttcacgcagattctccgggtcaaggaccgtgatgacttccccgtcgtgttggtc gggaacaaggcagatctggaggcacagcgccaggtcccccgatcagaagcatctgccttc ggtgcctcccaccacgtggcctactttgaggcctcggccaaactgcgtctcaacgtggat gaggcttttgagcagctggtgcgggctgtccggaaataccaggaacaagagctcccaccc agccctcccagtgcccccaggaagaagggcaggggctgcccctgcgtcctcctgtag

Rhinopithecus roxellana (golden snub-nosed monkey): 104669078 Help Entry 104669078         CDS       T03989                                  Gene name NRAS Definition (RefSeq) GTPase NRas   KO K07828   GTPase NRas Organism rro  Rhinopithecus roxellana (golden snub-nosed monkey) Pathway rro01521   EGFR tyrosine kinase inhibitor resistance rro01522   Endocrine resistance rro04010   MAPK signaling pathway rro04012   ErbB signaling pathway rro04014   Ras signaling pathway rro04015   Rap1 signaling pathway rro04062   Chemokine signaling pathway rro04068   FoxO signaling pathway rro04071   Sphingolipid signaling pathway rro04072   Phospholipase D signaling pathway rro04137   Mitophagy - animal rro04140   Autophagy - animal rro04150   mTOR signaling pathway rro04151   PI3K-Akt signaling pathway rro04210   Apoptosis rro04211   Longevity regulating pathway rro04213   Longevity regulating pathway - multiple species rro04218   Cellular senescence rro04360   Axon guidance rro04370   VEGF signaling pathway rro04371   Apelin signaling pathway rro04540   Gap junction rro04550   Signaling pathways regulating pluripotency of stem cells rro04625   C-type lectin receptor signaling pathway rro04650   Natural killer cell mediated cytotoxicity rro04660   T cell receptor signaling pathway rro04662   B cell receptor signaling pathway rro04664   Fc epsilon RI signaling pathway rro04714   Thermogenesis rro04720   Long-term potentiation rro04722   Neurotrophin signaling pathway rro04725   Cholinergic synapse rro04726   Serotonergic synapse rro04730   Long-term depression rro04810   Regulation of actin cytoskeleton rro04910   Insulin signaling pathway rro04912   GnRH signaling pathway rro04915   Estrogen signaling pathway rro04916   Melanogenesis rro04917   Prolactin signaling pathway rro04919   Thyroid hormone signaling pathway rro04921   Oxytocin signaling pathway rro04926   Relaxin signaling pathway rro04929   GnRH secretion rro04933   AGE-RAGE signaling pathway in diabetic complications rro04935   Growth hormone synthesis, secretion and action rro05010   Alzheimer disease rro05022   Pathways of neurodegeneration - multiple diseases rro05034   Alcoholism rro05160   Hepatitis C rro05161   Hepatitis B rro05163   Human cytomegalovirus infection rro05165   Human papillomavirus infection rro05166   Human T-cell leukemia virus 1 infection rro05167   Kaposi sarcoma-associated herpesvirus infection rro05170   Human immunodeficiency virus 1 infection rro05200   Pathways in cancer rro05203   Viral carcinogenesis rro05205   Proteoglycans in cancer rro05206   MicroRNAs in cancer rro05210   Colorectal cancer rro05211   Renal cell carcinoma rro05213   Endometrial cancer rro05214   Glioma rro05215   Prostate cancer rro05216   Thyroid cancer rro05218   Melanoma rro05219   Bladder cancer rro05220   Chronic myeloid leukemia rro05221   Acute myeloid leukemia rro05223   Non-small cell lung cancer rro05224   Breast cancer rro05225   Hepatocellular carcinoma rro05226   Gastric cancer rro05230   Central carbon metabolism in cancer rro05231   Choline metabolism in cancer rro05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:rro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104669078 (NRAS)    04012 ErbB signaling pathway     104669078 (NRAS)    04014 Ras signaling pathway     104669078 (NRAS)    04015 Rap1 signaling pathway     104669078 (NRAS)    04370 VEGF signaling pathway     104669078 (NRAS)    04371 Apelin signaling pathway     104669078 (NRAS)    04068 FoxO signaling pathway     104669078 (NRAS)    04072 Phospholipase D signaling pathway     104669078 (NRAS)    04071 Sphingolipid signaling pathway     104669078 (NRAS)    04151 PI3K-Akt signaling pathway     104669078 (NRAS)    04150 mTOR signaling pathway     104669078 (NRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104669078 (NRAS)    04137 Mitophagy - animal     104669078 (NRAS)   09143 Cell growth and death    04210 Apoptosis     104669078 (NRAS)    04218 Cellular senescence     104669078 (NRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     104669078 (NRAS)    04550 Signaling pathways regulating pluripotency of stem cells     104669078 (NRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     104669078 (NRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     104669078 (NRAS)    04650 Natural killer cell mediated cytotoxicity     104669078 (NRAS)    04660 T cell receptor signaling pathway     104669078 (NRAS)    04662 B cell receptor signaling pathway     104669078 (NRAS)    04664 Fc epsilon RI signaling pathway     104669078 (NRAS)    04062 Chemokine signaling pathway     104669078 (NRAS)   09152 Endocrine system    04910 Insulin signaling pathway     104669078 (NRAS)    04929 GnRH secretion     104669078 (NRAS)    04912 GnRH signaling pathway     104669078 (NRAS)    04915 Estrogen signaling pathway     104669078 (NRAS)    04917 Prolactin signaling pathway     104669078 (NRAS)    04921 Oxytocin signaling pathway     104669078 (NRAS)    04926 Relaxin signaling pathway     104669078 (NRAS)    04935 Growth hormone synthesis, secretion and action     104669078 (NRAS)    04919 Thyroid hormone signaling pathway     104669078 (NRAS)    04916 Melanogenesis     104669078 (NRAS)   09156 Nervous system    04725 Cholinergic synapse     104669078 (NRAS)    04726 Serotonergic synapse     104669078 (NRAS)    04720 Long-term potentiation     104669078 (NRAS)    04730 Long-term depression     104669078 (NRAS)    04722 Neurotrophin signaling pathway     104669078 (NRAS)   09158 Development and regeneration    04360 Axon guidance     104669078 (NRAS)   09149 Aging    04211 Longevity regulating pathway     104669078 (NRAS)    04213 Longevity regulating pathway - multiple species     104669078 (NRAS)   09159 Environmental adaptation    04714 Thermogenesis     104669078 (NRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104669078 (NRAS)    05206 MicroRNAs in cancer     104669078 (NRAS)    05205 Proteoglycans in cancer     104669078 (NRAS)    05203 Viral carcinogenesis     104669078 (NRAS)    05230 Central carbon metabolism in cancer     104669078 (NRAS)    05231 Choline metabolism in cancer     104669078 (NRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     104669078 (NRAS)   09162 Cancer: specific types    05210 Colorectal cancer     104669078 (NRAS)    05225 Hepatocellular carcinoma     104669078 (NRAS)    05226 Gastric cancer     104669078 (NRAS)    05214 Glioma     104669078 (NRAS)    05216 Thyroid cancer     104669078 (NRAS)    05221 Acute myeloid leukemia     104669078 (NRAS)    05220 Chronic myeloid leukemia     104669078 (NRAS)    05218 Melanoma     104669078 (NRAS)    05211 Renal cell carcinoma     104669078 (NRAS)    05219 Bladder cancer     104669078 (NRAS)    05215 Prostate cancer     104669078 (NRAS)    05213 Endometrial cancer     104669078 (NRAS)    05224 Breast cancer     104669078 (NRAS)    05223 Non-small cell lung cancer     104669078 (NRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     104669078 (NRAS)    05022 Pathways of neurodegeneration - multiple diseases     104669078 (NRAS)   09165 Substance dependence    05034 Alcoholism     104669078 (NRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     104669078 (NRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104669078 (NRAS)    05170 Human immunodeficiency virus 1 infection     104669078 (NRAS)    05161 Hepatitis B     104669078 (NRAS)    05160 Hepatitis C     104669078 (NRAS)    05163 Human cytomegalovirus infection     104669078 (NRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     104669078 (NRAS)    05165 Human papillomavirus infection     104669078 (NRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     104669078 (NRAS)    01522 Endocrine resistance     104669078 (NRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rro04131]     104669078 (NRAS)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:rro04147]     104669078 (NRAS)    04031 GTP-binding proteins [BR:rro04031]     104669078 (NRAS) Membrane trafficking [BR:rro04131]  Endocytosis   Macropinocytosis    Ras GTPases     104669078 (NRAS) Exosome [BR:rro04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    104669078 (NRAS)   Exosomal proteins of other body fluids (saliva and urine)    104669078 (NRAS)   Exosomal proteins of breast cancer cells    104669078 (NRAS)   Exosomal proteins of colorectal cancer cells    104669078 (NRAS) GTP-binding proteins [BR:rro04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     104669078 (NRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin ParA Ldh_1_N Motif Other DBs NCBI-GeneID:  104669078 NCBI-ProteinID:  XP_010370267 UniProt:  A0A2K6PPE8 LinkDB All DBs Position 8 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG CMGLPCVVM NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac agaaaacaggtggttatagatggtgaaacctgtttgttggacatactggatacagctgga caagaagagtacagtgccatgagagatcaatacatgaggacaggcgaaggcttcctctgt gtatttgccatcaataatagcaagtcatttgcggatattaacctctacagggagcagatt aagcgagtaaaagactcggatgatgtacctatggtgctagtgggaaacaagtgtgatttg ccaacaaggacagttgatacaaagcaagcccacgaactggccaagagttacgggattcca ttcattgaaacctcagccaagaccagacagggtgttgaagatgctttttacacactggta agagaaatacgccagtaccgaatgaaaaaactcaacagcagtgatgatgggactcagggt tgtatgggattgccatgtgtggtgatgtaa

Rhinopithecus roxellana (golden snub-nosed monkey): 104670041 Help Entry 104670041         CDS       T03989                                  Gene name KRAS Definition (RefSeq) GTPase KRas isoform X1   KO K07827   GTPase KRas Organism rro  Rhinopithecus roxellana (golden snub-nosed monkey) Pathway rro01521   EGFR tyrosine kinase inhibitor resistance rro01522   Endocrine resistance rro04010   MAPK signaling pathway rro04012   ErbB signaling pathway rro04014   Ras signaling pathway rro04015   Rap1 signaling pathway rro04062   Chemokine signaling pathway rro04068   FoxO signaling pathway rro04071   Sphingolipid signaling pathway rro04072   Phospholipase D signaling pathway rro04137   Mitophagy - animal rro04140   Autophagy - animal rro04150   mTOR signaling pathway rro04151   PI3K-Akt signaling pathway rro04210   Apoptosis rro04211   Longevity regulating pathway rro04213   Longevity regulating pathway - multiple species rro04218   Cellular senescence rro04360   Axon guidance rro04370   VEGF signaling pathway rro04371   Apelin signaling pathway rro04540   Gap junction rro04550   Signaling pathways regulating pluripotency of stem cells rro04625   C-type lectin receptor signaling pathway rro04650   Natural killer cell mediated cytotoxicity rro04660   T cell receptor signaling pathway rro04662   B cell receptor signaling pathway rro04664   Fc epsilon RI signaling pathway rro04714   Thermogenesis rro04720   Long-term potentiation rro04722   Neurotrophin signaling pathway rro04725   Cholinergic synapse rro04726   Serotonergic synapse rro04730   Long-term depression rro04810   Regulation of actin cytoskeleton rro04910   Insulin signaling pathway rro04912   GnRH signaling pathway rro04914   Progesterone-mediated oocyte maturation rro04915   Estrogen signaling pathway rro04916   Melanogenesis rro04917   Prolactin signaling pathway rro04919   Thyroid hormone signaling pathway rro04921   Oxytocin signaling pathway rro04926   Relaxin signaling pathway rro04929   GnRH secretion rro04933   AGE-RAGE signaling pathway in diabetic complications rro04935   Growth hormone synthesis, secretion and action rro04960   Aldosterone-regulated sodium reabsorption rro05010   Alzheimer disease rro05022   Pathways of neurodegeneration - multiple diseases rro05034   Alcoholism rro05160   Hepatitis C rro05161   Hepatitis B rro05163   Human cytomegalovirus infection rro05165   Human papillomavirus infection rro05166   Human T-cell leukemia virus 1 infection rro05167   Kaposi sarcoma-associated herpesvirus infection rro05170   Human immunodeficiency virus 1 infection rro05200   Pathways in cancer rro05203   Viral carcinogenesis rro05205   Proteoglycans in cancer rro05206   MicroRNAs in cancer rro05210   Colorectal cancer rro05211   Renal cell carcinoma rro05212   Pancreatic cancer rro05213   Endometrial cancer rro05214   Glioma rro05215   Prostate cancer rro05216   Thyroid cancer rro05218   Melanoma rro05219   Bladder cancer rro05220   Chronic myeloid leukemia rro05221   Acute myeloid leukemia rro05223   Non-small cell lung cancer rro05224   Breast cancer rro05225   Hepatocellular carcinoma rro05226   Gastric cancer rro05230   Central carbon metabolism in cancer rro05231   Choline metabolism in cancer rro05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:rro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104670041 (KRAS)    04012 ErbB signaling pathway     104670041 (KRAS)    04014 Ras signaling pathway     104670041 (KRAS)    04015 Rap1 signaling pathway     104670041 (KRAS)    04370 VEGF signaling pathway     104670041 (KRAS)    04371 Apelin signaling pathway     104670041 (KRAS)    04068 FoxO signaling pathway     104670041 (KRAS)    04072 Phospholipase D signaling pathway     104670041 (KRAS)    04071 Sphingolipid signaling pathway     104670041 (KRAS)    04151 PI3K-Akt signaling pathway     104670041 (KRAS)    04150 mTOR signaling pathway     104670041 (KRAS)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104670041 (KRAS)    04137 Mitophagy - animal     104670041 (KRAS)   09143 Cell growth and death    04210 Apoptosis     104670041 (KRAS)    04218 Cellular senescence     104670041 (KRAS)   09144 Cellular community - eukaryotes    04540 Gap junction     104670041 (KRAS)    04550 Signaling pathways regulating pluripotency of stem cells     104670041 (KRAS)   09142 Cell motility    04810 Regulation of actin cytoskeleton     104670041 (KRAS)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     104670041 (KRAS)    04650 Natural killer cell mediated cytotoxicity     104670041 (KRAS)    04660 T cell receptor signaling pathway     104670041 (KRAS)    04662 B cell receptor signaling pathway     104670041 (KRAS)    04664 Fc epsilon RI signaling pathway     104670041 (KRAS)    04062 Chemokine signaling pathway     104670041 (KRAS)   09152 Endocrine system    04910 Insulin signaling pathway     104670041 (KRAS)    04929 GnRH secretion     104670041 (KRAS)    04912 GnRH signaling pathway     104670041 (KRAS)    04915 Estrogen signaling pathway     104670041 (KRAS)    04914 Progesterone-mediated oocyte maturation     104670041 (KRAS)    04917 Prolactin signaling pathway     104670041 (KRAS)    04921 Oxytocin signaling pathway     104670041 (KRAS)    04926 Relaxin signaling pathway     104670041 (KRAS)    04935 Growth hormone synthesis, secretion and action     104670041 (KRAS)    04919 Thyroid hormone signaling pathway     104670041 (KRAS)    04916 Melanogenesis     104670041 (KRAS)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     104670041 (KRAS)   09156 Nervous system    04725 Cholinergic synapse     104670041 (KRAS)    04726 Serotonergic synapse     104670041 (KRAS)    04720 Long-term potentiation     104670041 (KRAS)    04730 Long-term depression     104670041 (KRAS)    04722 Neurotrophin signaling pathway     104670041 (KRAS)   09158 Development and regeneration    04360 Axon guidance     104670041 (KRAS)   09149 Aging    04211 Longevity regulating pathway     104670041 (KRAS)    04213 Longevity regulating pathway - multiple species     104670041 (KRAS)   09159 Environmental adaptation    04714 Thermogenesis     104670041 (KRAS)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     104670041 (KRAS)    05206 MicroRNAs in cancer     104670041 (KRAS)    05205 Proteoglycans in cancer     104670041 (KRAS)    05203 Viral carcinogenesis     104670041 (KRAS)    05230 Central carbon metabolism in cancer     104670041 (KRAS)    05231 Choline metabolism in cancer     104670041 (KRAS)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     104670041 (KRAS)   09162 Cancer: specific types    05210 Colorectal cancer     104670041 (KRAS)    05212 Pancreatic cancer     104670041 (KRAS)    05225 Hepatocellular carcinoma     104670041 (KRAS)    05226 Gastric cancer     104670041 (KRAS)    05214 Glioma     104670041 (KRAS)    05216 Thyroid cancer     104670041 (KRAS)    05221 Acute myeloid leukemia     104670041 (KRAS)    05220 Chronic myeloid leukemia     104670041 (KRAS)    05218 Melanoma     104670041 (KRAS)    05211 Renal cell carcinoma     104670041 (KRAS)    05219 Bladder cancer     104670041 (KRAS)    05215 Prostate cancer     104670041 (KRAS)    05213 Endometrial cancer     104670041 (KRAS)    05224 Breast cancer     104670041 (KRAS)    05223 Non-small cell lung cancer     104670041 (KRAS)   09164 Neurodegenerative disease    05010 Alzheimer disease     104670041 (KRAS)    05022 Pathways of neurodegeneration - multiple diseases     104670041 (KRAS)   09165 Substance dependence    05034 Alcoholism     104670041 (KRAS)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     104670041 (KRAS)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     104670041 (KRAS)    05170 Human immunodeficiency virus 1 infection     104670041 (KRAS)    05161 Hepatitis B     104670041 (KRAS)    05160 Hepatitis C     104670041 (KRAS)    05163 Human cytomegalovirus infection     104670041 (KRAS)    05167 Kaposi sarcoma-associated herpesvirus infection     104670041 (KRAS)    05165 Human papillomavirus infection     104670041 (KRAS)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     104670041 (KRAS)    01522 Endocrine resistance     104670041 (KRAS)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rro04131]     104670041 (KRAS)   09183 Protein families: signaling and cellular processes    04031 GTP-binding proteins [BR:rro04031]     104670041 (KRAS) Membrane trafficking [BR:rro04131]  Endocytosis   Macropinocytosis    Ras GTPases     104670041 (KRAS) GTP-binding proteins [BR:rro04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     104670041 (KRAS) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 G-alpha FeoB_N ATP_bind_1 Gtr1_RagA Septin AAA_25 CbiA Motif Other DBs NCBI-GeneID:  104670041 NCBI-ProteinID:  XP_030794568 LinkDB All DBs Position 10 AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKKISKEEKTPGC VKIKKCIIM NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg atacagctaattcagaatcattttgtggacgaatatgatccaacaatagaggattcctac aggaagcaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt caagaggagtacagtgcaatgagggaccaatacatgaggactggggagggctttctttgt gtatttgccataaataatactaaatcatttgaagatattcaccattatagagaacaaatt aaaagagttaaggactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg ccttctagaacagtagacacaaaacaggctcaggacttagcaagaagttacggaattcct tttattgaaacatcagcaaagacaagacagagagtggaggatgctttttatacattggtg agagagatccgacaatacagattgaaaaaaatcagcaaagaagaaaagactcctggctgt gtgaaaattaaaaaatgcattataatgtaa

Rhinopithecus roxellana (golden snub-nosed monkey): 104681946 Help Entry 104681946         CDS       T03989                                  Gene name RRAS2 Definition (RefSeq) ras-related protein R-Ras2   KO K07830   Ras-related protein R-Ras2 Organism rro  Rhinopithecus roxellana (golden snub-nosed monkey) Pathway rro04010   MAPK signaling pathway rro04014   Ras signaling pathway rro04024   cAMP signaling pathway rro04072   Phospholipase D signaling pathway rro04137   Mitophagy - animal rro04140   Autophagy - animal rro04218   Cellular senescence rro04371   Apelin signaling pathway rro04625   C-type lectin receptor signaling pathway rro04810   Regulation of actin cytoskeleton rro05205   Proteoglycans in cancer Brite KEGG Orthology (KO) [BR:rro00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     104681946 (RRAS2)    04014 Ras signaling pathway     104681946 (RRAS2)    04371 Apelin signaling pathway     104681946 (RRAS2)    04072 Phospholipase D signaling pathway     104681946 (RRAS2)    04024 cAMP signaling pathway     104681946 (RRAS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104681946 (RRAS2)    04137 Mitophagy - animal     104681946 (RRAS2)   09143 Cell growth and death    04218 Cellular senescence     104681946 (RRAS2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     104681946 (RRAS2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     104681946 (RRAS2)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     104681946 (RRAS2)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:rro04147]     104681946 (RRAS2)    04031 GTP-binding proteins [BR:rro04031]     104681946 (RRAS2) Exosome [BR:rro04147]  Exosomal proteins   Exosomal proteins of colorectal cancer cells    104681946 (RRAS2)   Exosomal proteins of bladder cancer cells    104681946 (RRAS2) GTP-binding proteins [BR:rro04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     104681946 (RRAS2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase ATP_bind_1 DUF2075 Motif Other DBs NCBI-GeneID:  104681946 NCBI-ProteinID:  XP_030773779 LinkDB All DBs Position 15 AA seq 204 aa AA seqDB search MAAAGWRDGSGQEKYRLVVVGGGGVGKSALTIQFIQSYFVTDYDPTIEDSYTKQCVIDDR AARLDILDTAGQEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEF PMILIGNKADLDHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQE QECPPSPEPTRKEKDKKGCHCVIF NT seq 615 nt NT seq  +upstreamnt  +downstreamnt atggccgcggccggctggcgggacggctccggccaggagaagtaccggctcgtggtggtc ggcgggggtggcgtgggcaagtcggcgctcaccatccagttcatccagtcctattttgta acggattatgatccaaccattgaagattcttatacaaagcagtgtgtgatagatgacaga gcagcccggctagatattttggatacagcaggacaagaagagtttggagccatgagagaa cagtatatgaggactggcgagggcttcctgttggtcttttcagtcacagatagaggcagt tttgaagaaatctataagtttcaaagacaaattctcagagtaaaggatcgtgatgagttc ccaatgattttaattggtaataaagcagatctggatcatcaaagacaggtaacacaggaa gaaggacagcagttagcacggcaacttaaggtcacatacatggaggcatcagcaaagatt aggatgaatgtagatcaagctttccatgaacttgtccgggttatcaggaaatttcaagag caggaatgtcctccttcaccagaaccaacacgcaaagaaaaagacaagaaaggctgccat tgtgtcattttctag

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