KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104654871
Entry
104654871         CDS       T03989                                 

Gene name
ADCY6
Definition
(RefSeq) adenylate cyclase type 6
  KO
K08046  adenylate cyclase 6 [EC:4.6.1.1]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230  Purine metabolism
rro01100  Metabolic pathways
rro01522  Endocrine resistance
rro04015  Rap1 signaling pathway
rro04022  cGMP-PKG signaling pathway
rro04024  cAMP signaling pathway
rro04062  Chemokine signaling pathway
rro04072  Phospholipase D signaling pathway
rro04114  Oocyte meiosis
rro04211  Longevity regulating pathway
rro04213  Longevity regulating pathway - multiple species
rro04261  Adrenergic signaling in cardiomyocytes
rro04270  Vascular smooth muscle contraction
rro04371  Apelin signaling pathway
rro04540  Gap junction
rro04611  Platelet activation
rro04713  Circadian entrainment
rro04714  Thermogenesis
rro04723  Retrograde endocannabinoid signaling
rro04724  Glutamatergic synapse
rro04725  Cholinergic synapse
rro04727  GABAergic synapse
rro04742  Taste transduction
rro04750  Inflammatory mediator regulation of TRP channels
rro04911  Insulin secretion
rro04912  GnRH signaling pathway
rro04913  Ovarian steroidogenesis
rro04914  Progesterone-mediated oocyte maturation
rro04915  Estrogen signaling pathway
rro04916  Melanogenesis
rro04918  Thyroid hormone synthesis
rro04921  Oxytocin signaling pathway
rro04923  Regulation of lipolysis in adipocytes
rro04924  Renin secretion
rro04925  Aldosterone synthesis and secretion
rro04926  Relaxin signaling pathway
rro04927  Cortisol synthesis and secretion
rro04928  Parathyroid hormone synthesis, secretion and action
rro04934  Cushing syndrome
rro04935  Growth hormone synthesis, secretion and action
rro04961  Endocrine and other factor-regulated calcium reabsorption
rro04962  Vasopressin-regulated water reabsorption
rro04970  Salivary secretion
rro04971  Gastric acid secretion
rro04972  Pancreatic secretion
rro04976  Bile secretion
rro05032  Morphine addiction
rro05163  Human cytomegalovirus infection
rro05166  Human T-cell leukemia virus 1 infection
rro05200  Pathways in cancer
rro05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rro00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    104654871 (ADCY6)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    104654871 (ADCY6)
   04371 Apelin signaling pathway
    104654871 (ADCY6)
   04072 Phospholipase D signaling pathway
    104654871 (ADCY6)
   04024 cAMP signaling pathway
    104654871 (ADCY6)
   04022 cGMP-PKG signaling pathway
    104654871 (ADCY6)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    104654871 (ADCY6)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104654871 (ADCY6)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104654871 (ADCY6)
   04062 Chemokine signaling pathway
    104654871 (ADCY6)
  09152 Endocrine system
   04911 Insulin secretion
    104654871 (ADCY6)
   04923 Regulation of lipolysis in adipocytes
    104654871 (ADCY6)
   04912 GnRH signaling pathway
    104654871 (ADCY6)
   04913 Ovarian steroidogenesis
    104654871 (ADCY6)
   04915 Estrogen signaling pathway
    104654871 (ADCY6)
   04914 Progesterone-mediated oocyte maturation
    104654871 (ADCY6)
   04921 Oxytocin signaling pathway
    104654871 (ADCY6)
   04926 Relaxin signaling pathway
    104654871 (ADCY6)
   04935 Growth hormone synthesis, secretion and action
    104654871 (ADCY6)
   04918 Thyroid hormone synthesis
    104654871 (ADCY6)
   04928 Parathyroid hormone synthesis, secretion and action
    104654871 (ADCY6)
   04916 Melanogenesis
    104654871 (ADCY6)
   04924 Renin secretion
    104654871 (ADCY6)
   04925 Aldosterone synthesis and secretion
    104654871 (ADCY6)
   04927 Cortisol synthesis and secretion
    104654871 (ADCY6)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104654871 (ADCY6)
   04270 Vascular smooth muscle contraction
    104654871 (ADCY6)
  09154 Digestive system
   04970 Salivary secretion
    104654871 (ADCY6)
   04971 Gastric acid secretion
    104654871 (ADCY6)
   04972 Pancreatic secretion
    104654871 (ADCY6)
   04976 Bile secretion
    104654871 (ADCY6)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    104654871 (ADCY6)
   04961 Endocrine and other factor-regulated calcium reabsorption
    104654871 (ADCY6)
  09156 Nervous system
   04724 Glutamatergic synapse
    104654871 (ADCY6)
   04727 GABAergic synapse
    104654871 (ADCY6)
   04725 Cholinergic synapse
    104654871 (ADCY6)
   04723 Retrograde endocannabinoid signaling
    104654871 (ADCY6)
  09157 Sensory system
   04742 Taste transduction
    104654871 (ADCY6)
   04750 Inflammatory mediator regulation of TRP channels
    104654871 (ADCY6)
  09149 Aging
   04211 Longevity regulating pathway
    104654871 (ADCY6)
   04213 Longevity regulating pathway - multiple species
    104654871 (ADCY6)
  09159 Environmental adaptation
   04713 Circadian entrainment
    104654871 (ADCY6)
   04714 Thermogenesis
    104654871 (ADCY6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104654871 (ADCY6)
  09165 Substance dependence
   05032 Morphine addiction
    104654871 (ADCY6)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    104654871 (ADCY6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    104654871 (ADCY6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104654871 (ADCY6)
   05163 Human cytomegalovirus infection
    104654871 (ADCY6)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    104654871 (ADCY6)
Enzymes [BR:rro01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     104654871 (ADCY6)
SSDB
Motif
Pfam: AC_N Guanylate_cyc DUF1053 HNOBA TBK1_ULD Shisa
Other DBs
NCBI-GeneID: 104654871
NCBI-ProteinID: XP_030794271
LinkDB
Position
10
AA seq 1169 aa
MSWFSGLLVPKVDERKTAWGERNGQKRSRRCGTRAGGFCTPRYMSCLRDAEPPSPTPAGP
PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTVGGTAEVAPDAVPRSGRSCWR
RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPARPQPAY
VALLACAAALFLGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLW
CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFLWKQLGANVLLFLCTN
VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT
KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC
LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV
HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA
YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPPRWVPDRAFSRTKDSKAF
RQMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEK
KYSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSILMLGIYASIFLLLLVTVLICAVYS
CGSLFPKALQHLSRSIVRSRAHSTAVGIFSVLLVFTSAIANMFTCNHTPIRTCAARMLNL
TPADITACHLQQLNYSLGLDAPLCEGTTPTCSFPEYFIGSVLLSLLASSVFLHISSIGKL
AMVFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTP
VILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAH
FLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEII
SEERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFN
NFQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAK
GYQLECRGVVKVKGKGEMTTYFLNGGPSS
NT seq 3510 nt   +upstreamnt  +downstreamnt
atgtcatggtttagtggcctcctggtgcctaaagtggatgaacggaaaacagcctggggt
gaacgcaatgggcagaagcgttcacggcgctgtggcactcgggcaggtggcttctgcacg
ccccgctatatgagctgcctccgggatgcagagccacccagccccacccctgcgggcccc
cctcggtgcccctggcaggatgacgccttcatccggaggggcggcccaggcaagggcaag
gagctggggttgcgggcagtggccctgggcttcgaggacaccgaggtgacaacgacagtg
ggcgggacagctgaggtggcgcccgacgcggtgcccaggagtgggcgatcctgctggcgc
cgtctggtgcaggtgttccagtcgaagcagttccgttcggccaagctggagcgcctgtac
cagcggtacttcttccagatgaaccagagcagcctgacgctgctgatggcggtgctggtg
ctgctcacggcggtgctgctggctttccacgcggcgcccgcccgccctcagcctgcctat
gtggccctgctggcctgcgccgccgctctgttcctggggctcatggtggtgtgtaaccgg
catagcttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcg
gcagtgcaggtcgggggcgccctcgcagcagacccacgcagcccctctgcgggcctctgg
tgccctgtgttcttcgtctacatcgcctacacgctcctccccatccgcatgcgggctgcg
gtcctcagcggcctgggcctctccaccctgcatttgatcttggcctggcaacttaaccgt
ggtgatgccttcctgtggaagcagctcggtgccaatgtgctgctgttcctctgcaccaac
gtcattggcatctgcacacactatccagcagaggtgtctcagcgccaggcctttcaggag
acccgtggttacatccaggcccggctccacctgcagcatgagaatcggcagcaggagcgg
ctgctgctgtcggtgttgccccagcatgttgccatggagatgaaagaagacatcaacaca
aaaaaagaagacatgatgttccataaaatctacatacagaagcatgacaatgtcagcatc
ctgtttgcagacattgagggcttcaccagcctggcatcccagtgcactgcacaggagctg
gtcatgaccctgaatgagctctttgcccggtttgacaagctggctgcggagaatcactgc
ctgaggatcaagatcttgggggactgttactactgtgtgtcagggctgccggaagcccgg
gccgaccatgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctg
gtacgtgaggtgacaggtgtgaatgtgaacatgcgcgtgggcatccacagcgggcgtgtg
cactgcggtgtccttggcttgcggaaatggcagttcgatgtgtggtccaatgatgtgacc
ctggccaaccacatggaggcaggaggccgggctggccgcatccacatcactcgggcaaca
ctgcagtacctgaacggggactacgaggtggagccaggccgtggtggcgagcgcaacgca
tacctcaaggagcagcacattgagactttcctcatcctgggcgccagccagaaacggaaa
gaggagaaggccatgctggccaagctgcagcggactcgggccaactccatggaagggctg
atgccgccgcgctgggtgcctgatcgtgccttttcccggaccaaggactccaaggccttc
cgccagatgggcattgatgattccagcaaagacaaccggggcacccaagatgccctgaac
cctgaggatgaggtggatgaattcctgagccgtgccatcgatgcccgcagcattgatcag
ctgcggaaggaccatgtgcgccggtttctgctcaccttccagagagaggatcttgagaag
aagtactcccggaaggtggatccccgcttcggagcctacgttgcctgtgccctgttggtc
ttctgcttcatctgcttcatccagcttctcatcttcccacactccatcttgatgcttggg
atctatgccagcatcttcctgctgctgctggtcaccgtgctgatctgtgccgtgtactcc
tgtggttctctgttccctaaggccctgcaacatctgtcccgcagcatcgttcgctcacgg
gcacatagcaccgcagttggcatcttttccgtcctgcttgtgttcacttctgccattgcc
aacatgttcacctgtaatcacacccccatacggacctgtgcagcccggatgctgaattta
acacctgctgacatcactgcctgccacctgcagcagctcaattactctctgggcctggat
gctcccctgtgtgagggcaccacgcccacctgcagcttccctgagtacttcatcgggagc
gtgctgctgagtctcttggccagctctgtcttcctgcacatcagcagcatcgggaagttg
gccatggtctttgtcttggggctcatctatttggtgctgcttctgctgggtcccccagcc
accatctttgacaactatgacctactgcttggcgtccatggcttggcttcttccaatgag
acctttgatgggctggactgtccagctgcagggagggtggccctcaaatatatgacccct
gtgattctgctggtgtttgcgctggcgctgtatctgcatgctcagcaggtggagtcgact
gcccgcctagacttcctctggaaactacaggcaacaggggagaaggaggagatggaggag
ctacaggcatacaaccggaggctgctgcataacattctgcccaaggacgtggccgcccac
ttcctggcccgggagcgtcgcaatgatgaactctactatcagtcgtgtgagtgtgtggct
gttatgtttgcctccattgccaacttctctgagttctatgtggagctggaggcaaacaat
gagggtgtcgagtgcctgcggctgctcaacgagatcatcgctgactttgatgagatcatc
agcgaggagcggttccggcagctggaaaagatcaagacaattggtagcacctacatggct
gcctcagggctgaacgccagcacctacgatcaggtgggccgctcccacatcactgccctg
gctgactacgccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaac
aatttccagatgaagattgggctgaacatgggcccagtcgtggcaggtgtcattggggct
cggaagccgcagtatgacatctgggggaacacagtgaatgtctctagtcgtatggacagc
acgggggtccccgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaag
ggctaccagctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacc
tacttcctcaatgggggccccagcagttag

KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104662674
Entry
104662674         CDS       T03989                                 

Gene name
ADCY4
Definition
(RefSeq) adenylate cyclase type 4 isoform X1
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230  Purine metabolism
rro01100  Metabolic pathways
rro01522  Endocrine resistance
rro04015  Rap1 signaling pathway
rro04020  Calcium signaling pathway
rro04022  cGMP-PKG signaling pathway
rro04024  cAMP signaling pathway
rro04062  Chemokine signaling pathway
rro04072  Phospholipase D signaling pathway
rro04114  Oocyte meiosis
rro04211  Longevity regulating pathway
rro04213  Longevity regulating pathway - multiple species
rro04261  Adrenergic signaling in cardiomyocytes
rro04270  Vascular smooth muscle contraction
rro04371  Apelin signaling pathway
rro04540  Gap junction
rro04611  Platelet activation
rro04713  Circadian entrainment
rro04714  Thermogenesis
rro04723  Retrograde endocannabinoid signaling
rro04724  Glutamatergic synapse
rro04725  Cholinergic synapse
rro04727  GABAergic synapse
rro04742  Taste transduction
rro04750  Inflammatory mediator regulation of TRP channels
rro04911  Insulin secretion
rro04912  GnRH signaling pathway
rro04913  Ovarian steroidogenesis
rro04914  Progesterone-mediated oocyte maturation
rro04915  Estrogen signaling pathway
rro04916  Melanogenesis
rro04918  Thyroid hormone synthesis
rro04921  Oxytocin signaling pathway
rro04923  Regulation of lipolysis in adipocytes
rro04925  Aldosterone synthesis and secretion
rro04926  Relaxin signaling pathway
rro04927  Cortisol synthesis and secretion
rro04928  Parathyroid hormone synthesis, secretion and action
rro04934  Cushing syndrome
rro04935  Growth hormone synthesis, secretion and action
rro04970  Salivary secretion
rro04971  Gastric acid secretion
rro04972  Pancreatic secretion
rro04976  Bile secretion
rro05032  Morphine addiction
rro05163  Human cytomegalovirus infection
rro05166  Human T-cell leukemia virus 1 infection
rro05200  Pathways in cancer
rro05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rro00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    104662674 (ADCY4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    104662674 (ADCY4)
   04371 Apelin signaling pathway
    104662674 (ADCY4)
   04020 Calcium signaling pathway
    104662674 (ADCY4)
   04072 Phospholipase D signaling pathway
    104662674 (ADCY4)
   04024 cAMP signaling pathway
    104662674 (ADCY4)
   04022 cGMP-PKG signaling pathway
    104662674 (ADCY4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    104662674 (ADCY4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104662674 (ADCY4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104662674 (ADCY4)
   04062 Chemokine signaling pathway
    104662674 (ADCY4)
  09152 Endocrine system
   04911 Insulin secretion
    104662674 (ADCY4)
   04923 Regulation of lipolysis in adipocytes
    104662674 (ADCY4)
   04912 GnRH signaling pathway
    104662674 (ADCY4)
   04913 Ovarian steroidogenesis
    104662674 (ADCY4)
   04915 Estrogen signaling pathway
    104662674 (ADCY4)
   04914 Progesterone-mediated oocyte maturation
    104662674 (ADCY4)
   04921 Oxytocin signaling pathway
    104662674 (ADCY4)
   04926 Relaxin signaling pathway
    104662674 (ADCY4)
   04935 Growth hormone synthesis, secretion and action
    104662674 (ADCY4)
   04918 Thyroid hormone synthesis
    104662674 (ADCY4)
   04928 Parathyroid hormone synthesis, secretion and action
    104662674 (ADCY4)
   04916 Melanogenesis
    104662674 (ADCY4)
   04925 Aldosterone synthesis and secretion
    104662674 (ADCY4)
   04927 Cortisol synthesis and secretion
    104662674 (ADCY4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104662674 (ADCY4)
   04270 Vascular smooth muscle contraction
    104662674 (ADCY4)
  09154 Digestive system
   04970 Salivary secretion
    104662674 (ADCY4)
   04971 Gastric acid secretion
    104662674 (ADCY4)
   04972 Pancreatic secretion
    104662674 (ADCY4)
   04976 Bile secretion
    104662674 (ADCY4)
  09156 Nervous system
   04724 Glutamatergic synapse
    104662674 (ADCY4)
   04727 GABAergic synapse
    104662674 (ADCY4)
   04725 Cholinergic synapse
    104662674 (ADCY4)
   04723 Retrograde endocannabinoid signaling
    104662674 (ADCY4)
  09157 Sensory system
   04742 Taste transduction
    104662674 (ADCY4)
   04750 Inflammatory mediator regulation of TRP channels
    104662674 (ADCY4)
  09149 Aging
   04211 Longevity regulating pathway
    104662674 (ADCY4)
   04213 Longevity regulating pathway - multiple species
    104662674 (ADCY4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    104662674 (ADCY4)
   04714 Thermogenesis
    104662674 (ADCY4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104662674 (ADCY4)
  09165 Substance dependence
   05032 Morphine addiction
    104662674 (ADCY4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    104662674 (ADCY4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    104662674 (ADCY4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104662674 (ADCY4)
   05163 Human cytomegalovirus infection
    104662674 (ADCY4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    104662674 (ADCY4)
Enzymes [BR:rro01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     104662674 (ADCY4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N DUF3180 CD52
Other DBs
NCBI-GeneID: 104662674
NCBI-ProteinID: XP_010362015
LinkDB
Position
5
AA seq 1190 aa
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLGIVLCALAALLAVAWASGRELTSDPS
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWVALLALGHAFLFTGGVVSAWDQV
SYFLFVIFTVYAMLPLGMRDAAVAGLASSLSHLLVLGLYLGPQPDSRPALLPQLAANAVL
FLCGNVAGVYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAGMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHVDSPVSTSTPLQEKTLASFSPQWSLDRSRNPRGLDDELDTGDAK
FFQVIEQLNSQKQWKQSKDFNPLTLYFREKEMEKEYRLSAIPAFKYYEACTFLVFLSNFI
IQMLVTNRPPALAITYSITFLLFLLLLFVCFSEDLMRCALKGPKMLHWLPALSGLVATRP
GLRIALSTATILLVFALATTSLDLDSFLEFYSWRAPGNHPSAKLQKRKLRPREAKWLARA
HTVAQSQRSTLDAPHITPPPVRTPVLRFPSLPEIAESTPLDESGPDSSLGQLKPSTSHHC
AQETTCLFSSSSPLQFFFPTSSDCPFQAPNVSSMISNLSWELPGSLPLISVPYSMHCCTL
GFLSCSLFLHMSFELKLLLLLLWLAASCSLFLHSHAWLSDCLIVRLYLGPLDSRPGVLKE
PKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEREETETMENLTRLLLENVLP
AHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESNINHEGLECLRLLNEIIA
DFDELLSKPKFSGVEKIKTIGSTYMAATGLNATSGQDAQQDAERSCSHLGTMVEFAVALG
SKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLGKIQ
VTEETAWALQSLGYTCYSRGVIKVKGKGQLCTYFLNTDLTRSGPPSVTLG
NT seq 3573 nt   +upstreamnt  +downstreamnt
atggcccgcctcttcagcccccggccaccccccagcgaagacctcttctacgagacctac
tacagcctgagccagcagtacccgctgctgctgctgctgctggggatcgtgctctgtgcg
ctcgcggcgctgctcgcggttgcctgggccagcggcagggagctgacttcagacccgagc
ttcctgaccactgtgctgtgcgcgctgggcggcttctcgctgctgctgggcctcgcttcc
cgcgagcagcgactgcagcgctggacgcgtcctctgtccggcttggtgtgggtcgcgctg
ctagcgctaggccacgccttcctgttcaccgggggcgtggtgagcgcctgggaccaggtg
tcctattttctcttcgtcatcttcacggtgtatgccatgctgcccttgggcatgcgggac
gccgccgtcgcgggcctcgcctcctcactctcgcatctactggtcctggggctgtatctt
gggccacagccggactcacggcctgcactgctgccgcagttggcagcaaatgcagtgctg
ttcctgtgcgggaacgtggcaggagtgtaccacaaggcgctgatggagcgcgccctgcgg
gccacgttccgggaggcactcagctccttgcactcgcgccggcggctggacaccgaaaag
aagcaccaggaacaccttctcttgtccatccttcctgcctacctggcccgagagatgaaa
gcagagatcatggcacggctgcaggcaggacaggggtcacggccagaaagcaccaacaat
ttccacagcctctatgtcaagaggcaccagggagtcagtgtgctgtatgctgacattgtg
ggcttcacgcggctggccagcgagtgttcccctaaggagctggtgctcatgctcaatgag
ctctttggcaagtttgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg
ggggactgttactactgtgtctccggactgccactctcactgccagaccatgccatcaac
tgtgtgcgcatggggctggacatgtgccgggccatcaggaaactgcgggcagccactggc
gtggacatcaacatgcgtgtgggcgtgcactcaggcagtgtactctgtggagtcatcggg
ctgcagaagtggcagtatgacgtttggtcccatgatgttacactggctaaccacatggag
gcaggcggtgtaccagggcgagtgcacatcacaggggctaccctggccctgctggcaggg
gcttatgctgtggaggacgcaggcatggagcatcgggatccctaccttcgggagctaggg
gagcccacttatctggtcattgatccacgggcagaggaggaggatgagaagggcactgca
ggaggcttgctctcctcgcttgagggccccaagatgcgtccatcactgctgatgacccgt
tacctggagtcctggggtgcagccaagccttttgcccacctgagccacgtagacagccct
gtgtccacctccacccctctccaggagaagaccctggcttccttcagcccccagtggagc
ctagatcgaagccgtaacccccgtggactagatgatgaactggacaccggggatgccaag
ttcttccaggtcattgagcagctcaactcacagaaacagtggaagcagtcgaaggacttc
aacccactgacactgtacttcagagagaaggagatggagaaagagtaccgactctctgca
atccccgccttcaaatactatgaagcctgcaccttcctggtttttctctccaacttcatc
atccagatgctagtgacaaacaggcccccagctctggccatcacgtatagcatcaccttc
ctcctcttcctcctcctcctttttgtctgcttctcagaggacctgatgaggtgtgccctg
aaaggccccaagatgctgcattggctgcctgcactgtctggcttggtggccacacgacca
ggactgagaatagccttgagcaccgccaccatcctccttgtctttgccctggccactacc
agcctggatttagactcattcctagaattctattcctggagggcacctgggaatcaccca
tcagccaagttacagaagaggaagctaaggcccagagaggctaagtggctggcaagagct
cacacagtggctcagagtcagagaagtactcttgatgcccctcacataactcctccccca
gtgaggaccccagtgctgaggttcccttccctaccagaaatagcagaatccacccctttg
gacgagtctggccctgactcatctctgggtcagctgaaacccagcacaagccaccattgt
gcccaagaaactacctgcctcttcagctcctcatctcctctgcagttcttcttcccaaca
tcatcagactgccctttccaagctcccaatgtgtcctccatgatttccaacctctcctgg
gagctccctgggtctctgcctctcatcagtgtcccatactccatgcactgctgcacgctg
ggcttcctctcctgctccctctttctgcacatgagcttcgagctgaagctgctgctgctc
ctgctgtggctggcggcatcctgctccctcttcctacactcccacgcctggctgtccgac
tgcctcatcgtccgcctctatctgggccccttggactccaggcccggagtgctgaaggag
cccaaactcatgggtgctatctccttcttcatcttcttcttcaccctccttgtcctggct
cgccagaatgagtactactgccgcctggacttcctgtggaagaagaagctgaggcaggag
cgggaggagacagagacgatggagaacctgactcggctgctcttggagaatgtgctccct
gcacacgtggccccccagttcattggccagaaccggcgcaacgaggatctctaccaccag
tcctacgaatgcgtttgtgtcctcttcgcttcagtcccagacttcaaggagttctactct
gaatccaacatcaatcatgagggcctagagtgtctgaggctgctcaatgaaataattgct
gattttgatgagctgctctccaagcccaagttcagtggggtggagaagatcaagaccatt
ggcagcacctacatggcagccacaggattaaatgccacctctggacaggatgcacaacag
gatgctgaacggagctgcagccaccttggcactatggtggaatttgccgttgccctgggg
tctaagctggacgtcatcaacaagcattcattcaacaacttccgcctgcgtgtggggttg
aaccatggaccagtagtagctggagttattggggcccagaagccacaatatgacatttgg
ggcaacacagtgaacgtggccagccgcatggagagtacaggagtccttggcaaaatccaa
gtgactgaggagacagcctgggccctacagtccctgggctacacctgctacagccggggg
gtcatcaaggtgaaaggcaaagggcagctctgcacctacttcctgaacacagacttgaca
cgaagtggacctccttcagttaccctaggctga

KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104675683
Entry
104675683         CDS       T03989                                 

Gene name
ADCY8
Definition
(RefSeq) adenylate cyclase type 8 isoform X1
  KO
K08048  adenylate cyclase 8 [EC:4.6.1.1]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230  Purine metabolism
rro01100  Metabolic pathways
rro01522  Endocrine resistance
rro04015  Rap1 signaling pathway
rro04020  Calcium signaling pathway
rro04022  cGMP-PKG signaling pathway
rro04024  cAMP signaling pathway
rro04062  Chemokine signaling pathway
rro04072  Phospholipase D signaling pathway
rro04114  Oocyte meiosis
rro04211  Longevity regulating pathway
rro04213  Longevity regulating pathway - multiple species
rro04261  Adrenergic signaling in cardiomyocytes
rro04270  Vascular smooth muscle contraction
rro04371  Apelin signaling pathway
rro04540  Gap junction
rro04611  Platelet activation
rro04713  Circadian entrainment
rro04714  Thermogenesis
rro04720  Long-term potentiation
rro04723  Retrograde endocannabinoid signaling
rro04724  Glutamatergic synapse
rro04725  Cholinergic synapse
rro04727  GABAergic synapse
rro04742  Taste transduction
rro04750  Inflammatory mediator regulation of TRP channels
rro04911  Insulin secretion
rro04912  GnRH signaling pathway
rro04913  Ovarian steroidogenesis
rro04914  Progesterone-mediated oocyte maturation
rro04915  Estrogen signaling pathway
rro04916  Melanogenesis
rro04918  Thyroid hormone synthesis
rro04921  Oxytocin signaling pathway
rro04923  Regulation of lipolysis in adipocytes
rro04925  Aldosterone synthesis and secretion
rro04926  Relaxin signaling pathway
rro04927  Cortisol synthesis and secretion
rro04928  Parathyroid hormone synthesis, secretion and action
rro04934  Cushing syndrome
rro04935  Growth hormone synthesis, secretion and action
rro04970  Salivary secretion
rro04971  Gastric acid secretion
rro04972  Pancreatic secretion
rro04976  Bile secretion
rro05032  Morphine addiction
rro05163  Human cytomegalovirus infection
rro05166  Human T-cell leukemia virus 1 infection
rro05200  Pathways in cancer
rro05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rro00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    104675683 (ADCY8)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    104675683 (ADCY8)
   04371 Apelin signaling pathway
    104675683 (ADCY8)
   04020 Calcium signaling pathway
    104675683 (ADCY8)
   04072 Phospholipase D signaling pathway
    104675683 (ADCY8)
   04024 cAMP signaling pathway
    104675683 (ADCY8)
   04022 cGMP-PKG signaling pathway
    104675683 (ADCY8)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    104675683 (ADCY8)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    104675683 (ADCY8)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104675683 (ADCY8)
   04062 Chemokine signaling pathway
    104675683 (ADCY8)
  09152 Endocrine system
   04911 Insulin secretion
    104675683 (ADCY8)
   04923 Regulation of lipolysis in adipocytes
    104675683 (ADCY8)
   04912 GnRH signaling pathway
    104675683 (ADCY8)
   04913 Ovarian steroidogenesis
    104675683 (ADCY8)
   04915 Estrogen signaling pathway
    104675683 (ADCY8)
   04914 Progesterone-mediated oocyte maturation
    104675683 (ADCY8)
   04921 Oxytocin signaling pathway
    104675683 (ADCY8)
   04926 Relaxin signaling pathway
    104675683 (ADCY8)
   04935 Growth hormone synthesis, secretion and action
    104675683 (ADCY8)
   04918 Thyroid hormone synthesis
    104675683 (ADCY8)
   04928 Parathyroid hormone synthesis, secretion and action
    104675683 (ADCY8)
   04916 Melanogenesis
    104675683 (ADCY8)
   04925 Aldosterone synthesis and secretion
    104675683 (ADCY8)
   04927 Cortisol synthesis and secretion
    104675683 (ADCY8)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    104675683 (ADCY8)
   04270 Vascular smooth muscle contraction
    104675683 (ADCY8)
  09154 Digestive system
   04970 Salivary secretion
    104675683 (ADCY8)
   04971 Gastric acid secretion
    104675683 (ADCY8)
   04972 Pancreatic secretion
    104675683 (ADCY8)
   04976 Bile secretion
    104675683 (ADCY8)
  09156 Nervous system
   04724 Glutamatergic synapse
    104675683 (ADCY8)
   04727 GABAergic synapse
    104675683 (ADCY8)
   04725 Cholinergic synapse
    104675683 (ADCY8)
   04720 Long-term potentiation
    104675683 (ADCY8)
   04723 Retrograde endocannabinoid signaling
    104675683 (ADCY8)
  09157 Sensory system
   04742 Taste transduction
    104675683 (ADCY8)
   04750 Inflammatory mediator regulation of TRP channels
    104675683 (ADCY8)
  09149 Aging
   04211 Longevity regulating pathway
    104675683 (ADCY8)
   04213 Longevity regulating pathway - multiple species
    104675683 (ADCY8)
  09159 Environmental adaptation
   04713 Circadian entrainment
    104675683 (ADCY8)
   04714 Thermogenesis
    104675683 (ADCY8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104675683 (ADCY8)
  09165 Substance dependence
   05032 Morphine addiction
    104675683 (ADCY8)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    104675683 (ADCY8)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    104675683 (ADCY8)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104675683 (ADCY8)
   05163 Human cytomegalovirus infection
    104675683 (ADCY8)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    104675683 (ADCY8)
Enzymes [BR:rro01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     104675683 (ADCY8)
SSDB
Motif
Pfam: Guanylate_cyc AC_N DUF1053 TBK1_ULD
Other DBs
NCBI-GeneID: 104675683
NCBI-ProteinID: XP_030794046
LinkDB
Position
9
AA seq 1251 aa
MELSDVRCLTGSEELYTIHPTPPAGDGRSASRPQRLLWQTAVRHITEQRFIHGHRGGSSS
GSGGSGKASDPAGGGPNHHAPQLAGDSALPLYSLGPGERAHSTCGTKVFPERSGSGSASG
SGGGGDLGFLHLDCAPSNSDFFLNGGYSYRGVIFPTLRNSFKSRDLERLYQRYFLGQRRK
SEVVMNVLDVLTKLTLLVLHLSLASAPMDPLKGILLGFFTGIEVVICALVVVRKDTTSHT
YLQYSGVVTWVAMTTQILAAGLGYGLLGDGIGYVLFTLFATYSMLPLPLTWAILAGLGTS
LLQVILQVVIPRLAVISINQVVAQAVLFMCMNTAGIFISYLSDRAQRQAFLETRRCVEAR
LRLETENQRQERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADV
KGFTNLSTTLSAQELVRMLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAH
CCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKL
ESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPED
IVKESVSSSDQRNSGATFTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHV
QSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAF
IVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINE
TYLARNVIIFASILINFLGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTG
VLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETIYAGLFLRYDNFNHSGEDFLGTKEA
SLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVA
RHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDE
LLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWEHLCALADFSLALTESIQEINKH
SFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLIL
KDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLV
QSLNRQRQKQLLNENNNTGIIKGHYNRRTLLSPSGTEPGAQAEGTDKSDLP
NT seq 3756 nt   +upstreamnt  +downstreamnt
atggagctctccgatgtgcgctgccttacaggcagcgaggaactctacaccatccacccg
acgcccccggccggcgacggcaggagcgcttcccggccgcagcggctgttgtggcagacg
gcggtgcggcacatcaccgagcagcgcttcattcacggccaccggggaggcagcagcagc
gggagtggaggctcgggcaaagcctcggaccctgcgggcggcggccccaaccaccacgcg
ccgcagctggcaggcgactcggcgctgcccctctactcgctgggcccgggagagcgagcg
cacagcacctgcggcaccaaagtcttcccggaacgcagcgggagcggcagtgccagcggc
agcggaggcgggggcgacctgggcttcctgcaccttgactgtgcccctagcaactcggat
ttctttctcaatgggggctatagctaccgaggggtcattttccccaccctgcgcaactcc
ttcaaatctcgggatctggaacgcctctaccagcgctatttcttgggccagaggcgcaaa
tcggaagtggtgatgaacgtgctggacgtgctgaccaaactcactctcttggtcctgcac
ttgagcctggcctcggcccccatggacccgctcaagggcatcctgctgggcttcttcacc
ggcattgaggtggtgatctgcgccctggtggtggtcaggaaggacaccacctcccacacg
tacctgcagtacagcggcgtggtcacctgggtggccatgaccacccagatcctggcagca
ggcctcggctacgggctcctgggcgacggcataggctacgtgctcttcacgctcttcgcc
acctacagcatgctgccgctgccgctcacctgggccatcctggccggcctgggcacctcg
ctgctgcaggtcatcctccaagtggtcatcccccggctggcggtcatttccatcaaccag
gttgtggcccaggcagtgttattcatgtgtatgaacacagctggaatcttcatcagttac
ctgtcagaccgggcccagcgccaagctttcctggagactcggaggtgtgtggaggccagg
ctgcgcctggaaacagagaaccaaagacaggagcggctcgtgctttctgtactcccccgg
tttgttgtcctggaaatgatcaacgacatgaccaatgtggaagacgagcacctgcagcac
cagttccatcggatctacatccatcgctatgagaatgtcagtattctttttgcagatgtt
aaaggatttaccaacctctccacgaccttgtctgctcaggagctggtcaggatgctcaac
gagctctttgccagatttgatcgactggcccatgagcatcactgccttcgtattaaaatt
ctgggggactgctactactgcgtgtctggacttcctgagccccgccaggaccatgcccac
tgctgtgttgaaatgggtctcagcatgatcaaaaccatcaggtatgtgcggtcaagaaca
aaacacgatgttgacatgaggattggaatccactcaggctcggtgctgtgtggtgttctg
ggactaaggaagtggcagtttgatgtctggtcttgggatgtggacattgcaaacaaactc
gaatctggaggaatccccgggaggattcacatttccaaagccacgctagactgcctcaac
ggtgactataacgtggaagagggtcatggtaaagagaggaatgaattcctgaggaagcat
aatatcgagacttatttaattaagcagcctgaggacagcctgctgtccttgcctgaagat
atcgtcaaggagtcagtgagctcctcagaccagagaaacagtggggccacgttcactgaa
ggatcctggagccctgagctaccctttgataatatcgtggggaaacagaatactctggct
gccctaacaagaaattcaataaatctgcttccaaaccatcttgcacaagctttgcatgtc
cagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttgcggagtggc
gataaattgagaagagagcatatcaagccattctcactgatgtttaaagactccagcctg
gagcacaagtattctcaaatgagggatgaagtgttcaagtcaaacttggtctgtgcgttt
atcgttcttctatttatcacggcgatacaaagtttgcttccttcttcaagagtgatgcca
atgaccatccagttctccattctgattatgctgcactcggctctggtcctcatcaccaca
gcagaggattataagtgtttgcccctcatcctccggaaaacttgctgttggattaatgag
acctatttggcccggaacgtcatcatctttgcatccatcttgattaatttcctgggtgcc
atcttaaatatcctgtggtgtgattttgacaagtcgatacccttgaagaacctgactttc
aattcctcagctgtgtttacagatatctgctcctacccagagtactttgtcttcacgggg
gtgttggccatggtgacctgtgcagttttcctccgtctaaactccgtcctgaagctggca
gtgctgctgatcatgattgccatctatgccctgctcactgagaccatctacgcaggcctc
tttctgcgttatgataacttcaaccacagtggagaagatttcctggggaccaaggaggcg
tcgctgctgctgatggccatgttcctcctggctgtgttctaccatggacagcagctggag
tacacagcccgcctggatttcctttggcgagtgcaggccaaagaggagatcaatgagatg
aaggagctgagggaacacaatgagaacatgctccggaatatcttacccagccacgtggcc
cgccatttcctagagaaggaccgagacaatgaggagctgtattctcaatcctacgatgct
gttggggtgatgtttgcctccatcccaggatttgcggacttttactctcagactgaaatg
aataaccagggagtggaatgcctgcgcttgctgaatgagatcattgctgacttcgatgag
ttgcttggtgaagaccgatttcaagacattgaaaagattaagaccattggcagcacctac
atggccgtgtcaggcctgtcacctgaaaaacagcaatgtgaagacaagtgggaacatttg
tgtgctctggctgacttctcactcgccctgacagaaagcatacaggagatcaacaagcat
tcattcaacaattttgaactccggattggcatcagccatggctcagtggtagctggcgtt
attggcgctaagaaaccacagtatgacatttggggcaaaactgtgaacctggcaagccga
atggacagcacaggggttagtggccggatccaagtcccagaggagacctatctcatcctg
aaggaccagggctttgcctttgattaccgaggggagatctatgtgaagggcatcagtgaa
caggaaggaaaaatcaaaacgtactttctcctgggaagagtccaacccaacccattcatc
ttgcccccaagaagactgcctgggcagtactccctggctgcggttgtcctgggacttgtc
cagtccctcaataggcaaaggcagaagcagctactcaatgagaacaacaacacgggaatc
atcaagggtcattataaccggcggactttgttgtcacccagcgggacggagcctggagcc
caagctgaaggcactgacaaatctgatttgccataa

DBGET integrated database retrieval system