KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104655082
Entry
104655082         CDS       T03989                                 

Gene name
TGFBR2
Definition
(RefSeq) TGF-beta receptor type-2 isoform X1
  KO
K04388  TGF-beta receptor type-2 [EC:2.7.11.30]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04010  MAPK signaling pathway
rro04060  Cytokine-cytokine receptor interaction
rro04068  FoxO signaling pathway
rro04144  Endocytosis
rro04218  Cellular senescence
rro04350  TGF-beta signaling pathway
rro04380  Osteoclast differentiation
rro04390  Hippo signaling pathway
rro04520  Adherens junction
rro04659  Th17 cell differentiation
rro04926  Relaxin signaling pathway
rro04933  AGE-RAGE signaling pathway in diabetic complications
rro05142  Chagas disease
rro05161  Hepatitis B
rro05166  Human T-cell leukemia virus 1 infection
rro05200  Pathways in cancer
rro05202  Transcriptional misregulation in cancer
rro05210  Colorectal cancer
rro05212  Pancreatic cancer
rro05220  Chronic myeloid leukemia
rro05225  Hepatocellular carcinoma
rro05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104655082 (TGFBR2)
   04350 TGF-beta signaling pathway
    104655082 (TGFBR2)
   04390 Hippo signaling pathway
    104655082 (TGFBR2)
   04068 FoxO signaling pathway
    104655082 (TGFBR2)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    104655082 (TGFBR2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    104655082 (TGFBR2)
  09143 Cell growth and death
   04218 Cellular senescence
    104655082 (TGFBR2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    104655082 (TGFBR2)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    104655082 (TGFBR2)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    104655082 (TGFBR2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104655082 (TGFBR2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104655082 (TGFBR2)
   05202 Transcriptional misregulation in cancer
    104655082 (TGFBR2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    104655082 (TGFBR2)
   05212 Pancreatic cancer
    104655082 (TGFBR2)
   05225 Hepatocellular carcinoma
    104655082 (TGFBR2)
   05226 Gastric cancer
    104655082 (TGFBR2)
   05220 Chronic myeloid leukemia
    104655082 (TGFBR2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    104655082 (TGFBR2)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104655082 (TGFBR2)
   05161 Hepatitis B
    104655082 (TGFBR2)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    104655082 (TGFBR2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rro01001]
    104655082 (TGFBR2)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     104655082 (TGFBR2)
Protein kinases [BR:rro01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR2 family [OT]
   104655082 (TGFBR2)
SSDB
Motif
Pfam: ecTbetaR2 PK_Tyr_Ser-Thr Pkinase Pkinase_fungal APH
Other DBs
NCBI-GeneID: 104655082
NCBI-ProteinID: XP_010352771
UniProt: A0A2K6NGJ5
LinkDB
Position
1
AA seq 567 aa
MGRGLLRGLWPLHIVLWTRIASTIPPHVQKSVNNDMMVTDNNGAVKFPQLCKFCDVKFST
CDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHNPKLPYHDFILEDAASPK
CIMKEKKKPGETFFMCSCSSDECNDNIIFSEEYNTSNPDLLLVIFQVTGISLLPPLGVAI
SVIIIFYCYRVNRQQKLSSSWEAGKARKLMDFSEHCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLMRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDNVLRDRGRPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSE
LEHLDRLSGRSCSEEKIPEDGSLNTTK
NT seq 1704 nt   +upstreamnt  +downstreamnt
atgggtcgggggctgctcaggggcctgtggccgctgcacatcgtcttgtggacgcgtatc
gccagcacgatcccaccgcacgttcagaagtcggttaacaatgacatgatggtcactgac
aacaatggtgcagtcaagtttccacaactgtgtaaattttgtgatgtgaaattttccacc
tgtgacaaccagaaatcctgcatgagcaactgcagcatcacctccatctgtgaaaagcca
caggaagtctgtgtggctgtatggagaaagaacgacgagaacataacactagagacagtg
tgccataatcccaagctcccctaccatgactttattctggaagatgctgcttctccaaag
tgcattatgaaggaaaaaaaaaagcctggtgagaccttcttcatgtgttcctgtagctct
gatgagtgcaatgacaacatcatcttctcagaagaatacaacaccagcaatcctgacttg
ttgctagtcatatttcaagtgacaggcatcagcctcctgccaccactgggagttgccata
tctgtcatcatcatcttctactgctaccgtgttaatcggcagcagaagctgagttcatcc
tgggaagctggcaaggcacggaagctcatggacttcagcgagcactgtgccatcatcctg
gaagacgaccgctctgacatcagctccacatgcgccaacaacatcaaccacaacacagag
ctgctgcccattgaactggacaccctggtgggaaaaggtcgctttgctgaggtctataag
gccaagctgaagcagaacacttcagagcagtttgagacagtggcagtcaagatctttccc
tatgaggagtatgcctcttggaagacggagaaggacatcttctcagacatcaacctgaag
catgagaacatactccagttcctgacagctgaggagcggaagacggagttggggaaacag
tactggctgatcactgccttccatgccaagggcaacctacaggagtacctgatgcggcat
gtcatcagctgggaggacctgcgcaagctgggcagctccctcgcccggggcattgctcac
ctccacagtgatcacactccgtgcgggaggcccaagatgcccatcgtgcacagggacctc
aagagctccaatatcctcgtgaagaacgacctgacctgctgcctctgtgactttgggcta
tccctgcgtctggaccctaccctgtccgtggatgacctggctaacagcggccaggtggga
actgcaagatacatggctccagaagtcctagaatccaggatgaatttggagaatgtagag
tccttcaagcagaccgatgtctactccatggctctggtgctctgggaaatgacatcgcgc
tgtaatgcagtgggagaagtaaaagattatgagcctccatttggttccaaggtgcgggag
cacccctgtgtcgaaagcatgaaggacaacgtgttgagagatcgaggacgaccagaaatt
cccagcttctggctcaaccaccagggcatccagatggtgtgtgagacgttgactgagtgc
tgggaccacgacccagaggcccgtctcacagcccagtgtgtggcagaacgcttcagtgag
ctggagcacctggacaggctctcggggaggagctgctcagaggagaagattcctgaagac
ggctccctaaacactaccaaatag

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