KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104656469
Entry
104656469         CDS       T03989                                 

Gene name
CHUK
Definition
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1
  KO
K04467  inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01523  Antifolate resistance
rro04010  MAPK signaling pathway
rro04014  Ras signaling pathway
rro04062  Chemokine signaling pathway
rro04064  NF-kappa B signaling pathway
rro04068  FoxO signaling pathway
rro04150  mTOR signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04210  Apoptosis
rro04380  Osteoclast differentiation
rro04620  Toll-like receptor signaling pathway
rro04621  NOD-like receptor signaling pathway
rro04622  RIG-I-like receptor signaling pathway
rro04623  Cytosolic DNA-sensing pathway
rro04625  C-type lectin receptor signaling pathway
rro04657  IL-17 signaling pathway
rro04658  Th1 and Th2 cell differentiation
rro04659  Th17 cell differentiation
rro04660  T cell receptor signaling pathway
rro04662  B cell receptor signaling pathway
rro04668  TNF signaling pathway
rro04920  Adipocytokine signaling pathway
rro05010  Alzheimer disease
rro05132  Salmonella infection
rro05135  Yersinia infection
rro05142  Chagas disease
rro05145  Toxoplasmosis
rro05160  Hepatitis C
rro05161  Hepatitis B
rro05162  Measles
rro05163  Human cytomegalovirus infection
rro05164  Influenza A
rro05165  Human papillomavirus infection
rro05166  Human T-cell leukemia virus 1 infection
rro05167  Kaposi sarcoma-associated herpesvirus infection
rro05168  Herpes simplex virus 1 infection
rro05169  Epstein-Barr virus infection
rro05170  Human immunodeficiency virus 1 infection
rro05171  Coronavirus disease - COVID-19
rro05200  Pathways in cancer
rro05212  Pancreatic cancer
rro05215  Prostate cancer
rro05220  Chronic myeloid leukemia
rro05221  Acute myeloid leukemia
rro05222  Small cell lung cancer
rro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rro05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104656469 (CHUK)
   04014 Ras signaling pathway
    104656469 (CHUK)
   04064 NF-kappa B signaling pathway
    104656469 (CHUK)
   04668 TNF signaling pathway
    104656469 (CHUK)
   04068 FoxO signaling pathway
    104656469 (CHUK)
   04151 PI3K-Akt signaling pathway
    104656469 (CHUK)
   04150 mTOR signaling pathway
    104656469 (CHUK)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    104656469 (CHUK)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    104656469 (CHUK)
   04621 NOD-like receptor signaling pathway
    104656469 (CHUK)
   04622 RIG-I-like receptor signaling pathway
    104656469 (CHUK)
   04623 Cytosolic DNA-sensing pathway
    104656469 (CHUK)
   04625 C-type lectin receptor signaling pathway
    104656469 (CHUK)
   04660 T cell receptor signaling pathway
    104656469 (CHUK)
   04658 Th1 and Th2 cell differentiation
    104656469 (CHUK)
   04659 Th17 cell differentiation
    104656469 (CHUK)
   04657 IL-17 signaling pathway
    104656469 (CHUK)
   04662 B cell receptor signaling pathway
    104656469 (CHUK)
   04062 Chemokine signaling pathway
    104656469 (CHUK)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    104656469 (CHUK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104656469 (CHUK)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104656469 (CHUK)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104656469 (CHUK)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104656469 (CHUK)
   05221 Acute myeloid leukemia
    104656469 (CHUK)
   05220 Chronic myeloid leukemia
    104656469 (CHUK)
   05215 Prostate cancer
    104656469 (CHUK)
   05222 Small cell lung cancer
    104656469 (CHUK)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104656469 (CHUK)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    104656469 (CHUK)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104656469 (CHUK)
   05135 Yersinia infection
    104656469 (CHUK)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104656469 (CHUK)
   05170 Human immunodeficiency virus 1 infection
    104656469 (CHUK)
   05161 Hepatitis B
    104656469 (CHUK)
   05160 Hepatitis C
    104656469 (CHUK)
   05171 Coronavirus disease - COVID-19
    104656469 (CHUK)
   05164 Influenza A
    104656469 (CHUK)
   05162 Measles
    104656469 (CHUK)
   05168 Herpes simplex virus 1 infection
    104656469 (CHUK)
   05163 Human cytomegalovirus infection
    104656469 (CHUK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104656469 (CHUK)
   05169 Epstein-Barr virus infection
    104656469 (CHUK)
   05165 Human papillomavirus infection
    104656469 (CHUK)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104656469 (CHUK)
   05142 Chagas disease
    104656469 (CHUK)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    104656469 (CHUK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rro01001]
    104656469 (CHUK)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     104656469 (CHUK)
Protein kinases [BR:rro01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   104656469 (CHUK)
SSDB
Motif
Pfam: IKBKB_SDD Pkinase PK_Tyr_Ser-Thr IKKbetaNEMObind Pkinase_fungal Kdo TBK1_ULD
Other DBs
NCBI-GeneID: 104656469
NCBI-ProteinID: XP_010354387
UniProt: A0A2K6RAC3
LinkDB
Position
11
AA seq 745 aa
MERPPGLRPGAGGPWEMRERLGTGGFGNVCLYQHRELDLKIAIKSCRLELSTKNRERWCH
EIQIMKKLNHANVVKACDVPEELNILIHDVPLLAMEYCSGGDLRKLLNKPENCCGLKESQ
ILSLLSDIGSGIRYLHENKIIHRDLKPENIVLQDVGGKIIHKIIDLGYAKDVDQGSLCTS
FVGTLQYLAPELFENKPYTATVDYWSFGTMVFECIAGYRPFLHHLQPFTWHEKIKKKDPK
CIFACEEMSGEVRFSSHLPQPNSLCSLIVEPMENWLQLMLSWDPQQRGGPVDLTLKQPRC
FVLMDHILNLKIVHILNMTSAKIISFLLPPDESLHSLQSRIERETGINTGSQELLSETGI
SLDPRKPASQCVLDGVRGCDSYMVYLFDKSKTVYEGPFASRSLSDCVNYIVQDSKIQLPI
IQLRKVWAEAVHYVSGLKEDYSRLFQGQRAAMLSLLRYNANLTKMKNTLISASQQLKAKL
EFFHKSIQLDLERYSEQMTYGISSEKMLKAWKEMEEKAIHYAEVGVIGYLEDQIMSLHAE
IMELQKSPYGRRQGDLMESLEQRAIDLYKQLKHRPSDHSYSDSTEMVKIIVHTVQSQDRV
LKELFGHLSKLLGCKQKIIDLLPKVEVALSNIKEADNTVMFMQGKRQKEIWHLLKIACTQ
SSARSLVGSSLEGAVTPQTSVWLPPTSAEHDHSLSCVVTPPDGDTSAQMIEENLNCLGHL
STIIHEANEEQGNSMMNLDWSWLTE
NT seq 2238 nt   +upstreamnt  +downstreamnt
atggagcggcccccggggctgcggccgggcgcgggcgggccctgggagatgcgggagcgg
ttgggcaccggcggcttcgggaacgtctgtctgtaccagcatcgggaacttgatctcaaa
atagcaattaagtcttgtcgcctagagctaagtaccaaaaatagagaacgatggtgccac
gaaatccagattatgaagaagttgaaccatgccaacgttgtaaaggcctgtgatgttcct
gaagaactgaatattttgattcatgatgtgcctcttctagcaatggaatactgttctgga
ggagatctccgaaagctgctaaacaaaccagaaaattgttgtggacttaaagaaagccag
atactttctttactaagtgatatagggtctgggattcgatatttgcatgaaaacaaaatt
atacatcgagatctaaaacctgaaaacatagttcttcaggacgttggtggaaagataata
cataaaataattgatctgggatatgccaaagatgttgatcaaggaagtctgtgtacatct
tttgtgggaacactgcagtatctggccccagagctctttgagaataagccttacacagcc
actgttgattattggagctttgggaccatggtatttgaatgtattgctggatataggcct
tttttgcatcatctgcagccatttacctggcatgagaagattaagaagaaggatccaaag
tgtatatttgcatgtgaagagatgtcaggagaagttcggtttagtagccatttacctcaa
ccaaatagcctttgtagtttaatagtagaacccatggaaaactggctacagctgatgttg
agttgggaccctcagcagagaggaggacctgttgaccttactttgaagcagccgagatgt
tttgtactaatggatcacattttgaatttgaagatagtacacatcctaaatatgacttct
gcaaagataatttcttttctgttaccacctgatgaaagtcttcattcactacagtctcgt
attgagcgtgaaactggaataaatactggttctcaagaacttctttcagagacaggaatt
tctctggatcctcggaaaccagcctctcaatgtgttctagatggagttagaggctgtgat
agctatatggtttatttgtttgataaaagtaaaactgtgtatgaagggccatttgcttcc
agaagtttatctgattgtgtaaattatattgtacaggatagcaaaatacagcttccaatt
atacagctgcgtaaagtgtgggctgaagcagtgcactatgtgtctggactaaaagaagac
tacagcaggctctttcagggacaaagggcagcaatgttaagtcttcttagatataatgct
aacttaacaaaaatgaagaacactttgatctcagcatcacaacaactgaaagctaaattg
gagttttttcacaaaagcattcagcttgacttggagagatacagtgagcagatgacgtat
gggatatcttcagaaaaaatgctaaaagcatggaaagaaatggaagaaaaggccatccac
tatgctgaggtcggtgtcattggatacctggaggatcagattatgtctttgcatgctgaa
atcatggagctacagaagagcccctatggaagacgtcagggagacttgatggaatctctg
gaacagcgtgccattgatctatataagcagttaaaacacagaccttcagatcactcctac
agtgacagcacagagatggtgaaaatcattgtgcacactgtgcagagtcaggaccgtgtg
ctcaaggagctgtttggtcatttgagcaagttgttgggctgtaagcagaagattattgat
ctactccctaaggtggaagtggccctcagtaacatcaaagaagctgataatactgtcatg
ttcatgcagggaaaaaggcagaaagaaatatggcatctccttaaaattgcctgtacacag
agttctgcccggtcccttgtaggatccagtctagaaggtgcagtaacccctcagacgtca
gtatggctgcccccgacttcagcagaacatgatcattctctgtcatgtgtggtaactcct
ccagatggagatacttcagcacaaatgatagaagaaaatttgaactgccttggccattta
agcactattattcatgaggcaaatgaggaacagggcaatagtatgatgaatcttgattgg
agttggttaacagaatga

KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104666046
Entry
104666046         CDS       T03989                                 

Gene name
IKBKB
Definition
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit beta isoform X2
  KO
K07209  inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01523  Antifolate resistance
rro04010  MAPK signaling pathway
rro04014  Ras signaling pathway
rro04062  Chemokine signaling pathway
rro04064  NF-kappa B signaling pathway
rro04068  FoxO signaling pathway
rro04150  mTOR signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04210  Apoptosis
rro04380  Osteoclast differentiation
rro04620  Toll-like receptor signaling pathway
rro04621  NOD-like receptor signaling pathway
rro04622  RIG-I-like receptor signaling pathway
rro04623  Cytosolic DNA-sensing pathway
rro04625  C-type lectin receptor signaling pathway
rro04657  IL-17 signaling pathway
rro04658  Th1 and Th2 cell differentiation
rro04659  Th17 cell differentiation
rro04660  T cell receptor signaling pathway
rro04662  B cell receptor signaling pathway
rro04668  TNF signaling pathway
rro04722  Neurotrophin signaling pathway
rro04910  Insulin signaling pathway
rro04920  Adipocytokine signaling pathway
rro04930  Type II diabetes mellitus
rro04931  Insulin resistance
rro04932  Non-alcoholic fatty liver disease
rro05010  Alzheimer disease
rro05132  Salmonella infection
rro05135  Yersinia infection
rro05142  Chagas disease
rro05145  Toxoplasmosis
rro05160  Hepatitis C
rro05161  Hepatitis B
rro05162  Measles
rro05163  Human cytomegalovirus infection
rro05164  Influenza A
rro05165  Human papillomavirus infection
rro05166  Human T-cell leukemia virus 1 infection
rro05167  Kaposi sarcoma-associated herpesvirus infection
rro05168  Herpes simplex virus 1 infection
rro05169  Epstein-Barr virus infection
rro05170  Human immunodeficiency virus 1 infection
rro05171  Coronavirus disease - COVID-19
rro05200  Pathways in cancer
rro05206  MicroRNAs in cancer
rro05212  Pancreatic cancer
rro05215  Prostate cancer
rro05220  Chronic myeloid leukemia
rro05221  Acute myeloid leukemia
rro05222  Small cell lung cancer
rro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rro05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104666046 (IKBKB)
   04014 Ras signaling pathway
    104666046 (IKBKB)
   04064 NF-kappa B signaling pathway
    104666046 (IKBKB)
   04668 TNF signaling pathway
    104666046 (IKBKB)
   04068 FoxO signaling pathway
    104666046 (IKBKB)
   04151 PI3K-Akt signaling pathway
    104666046 (IKBKB)
   04150 mTOR signaling pathway
    104666046 (IKBKB)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    104666046 (IKBKB)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    104666046 (IKBKB)
   04621 NOD-like receptor signaling pathway
    104666046 (IKBKB)
   04622 RIG-I-like receptor signaling pathway
    104666046 (IKBKB)
   04623 Cytosolic DNA-sensing pathway
    104666046 (IKBKB)
   04625 C-type lectin receptor signaling pathway
    104666046 (IKBKB)
   04660 T cell receptor signaling pathway
    104666046 (IKBKB)
   04658 Th1 and Th2 cell differentiation
    104666046 (IKBKB)
   04659 Th17 cell differentiation
    104666046 (IKBKB)
   04657 IL-17 signaling pathway
    104666046 (IKBKB)
   04662 B cell receptor signaling pathway
    104666046 (IKBKB)
   04062 Chemokine signaling pathway
    104666046 (IKBKB)
  09152 Endocrine system
   04910 Insulin signaling pathway
    104666046 (IKBKB)
   04920 Adipocytokine signaling pathway
    104666046 (IKBKB)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    104666046 (IKBKB)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104666046 (IKBKB)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104666046 (IKBKB)
   05206 MicroRNAs in cancer
    104666046 (IKBKB)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104666046 (IKBKB)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104666046 (IKBKB)
   05221 Acute myeloid leukemia
    104666046 (IKBKB)
   05220 Chronic myeloid leukemia
    104666046 (IKBKB)
   05215 Prostate cancer
    104666046 (IKBKB)
   05222 Small cell lung cancer
    104666046 (IKBKB)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104666046 (IKBKB)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    104666046 (IKBKB)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    104666046 (IKBKB)
   04932 Non-alcoholic fatty liver disease
    104666046 (IKBKB)
   04931 Insulin resistance
    104666046 (IKBKB)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104666046 (IKBKB)
   05135 Yersinia infection
    104666046 (IKBKB)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104666046 (IKBKB)
   05170 Human immunodeficiency virus 1 infection
    104666046 (IKBKB)
   05161 Hepatitis B
    104666046 (IKBKB)
   05160 Hepatitis C
    104666046 (IKBKB)
   05171 Coronavirus disease - COVID-19
    104666046 (IKBKB)
   05164 Influenza A
    104666046 (IKBKB)
   05162 Measles
    104666046 (IKBKB)
   05168 Herpes simplex virus 1 infection
    104666046 (IKBKB)
   05163 Human cytomegalovirus infection
    104666046 (IKBKB)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104666046 (IKBKB)
   05169 Epstein-Barr virus infection
    104666046 (IKBKB)
   05165 Human papillomavirus infection
    104666046 (IKBKB)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104666046 (IKBKB)
   05142 Chagas disease
    104666046 (IKBKB)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    104666046 (IKBKB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rro01001]
    104666046 (IKBKB)
Enzymes [BR:rro01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     104666046 (IKBKB)
Protein kinases [BR:rro01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   104666046 (IKBKB)
SSDB
Motif
Pfam: IKBKB_SDD Pkinase PK_Tyr_Ser-Thr IKKbetaNEMObind Pkinase_fungal Kdo ubiquitin APH YrbL-PhoP_reg Med20 Glyco_hydro_65m
Other DBs
NCBI-GeneID: 104666046
NCBI-ProteinID: XP_010366341
UniProt: A0A2K6Q8Q7
LinkDB
Position
9
AA seq 756 aa
MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCL
EIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREG
AILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCT
SFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSE
VDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCF
KALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLA
LIPDKPATQCISDGKLNEGRTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRN
LAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLK
AKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMAL
QTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQS
FEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKI
ACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLE
NAIQDTVREQDQSFTALDWSWLQTEEEEHNCLEQAS
NT seq 2271 nt   +upstreamnt  +downstreamnt
atgagctggtcaccttccctgacaacccagacatgtggggcctgggaaatgaaagagcgc
cttgggacagggggatttggaaatgtcatccgatggcacaatcaggaaacaggtgagcag
attgccatcaagcagtgccggcaggagctcagcccccggaaccgagagcggtggtgcctg
gagatccagatcatgagaaggctgacccaccccaatgtggtggctgcccgagatgtccct
gaggggatgcagaacttggcgcccaatgacttgcccctgctggccatggagtattgccaa
ggaggagatctccggaagtacctgaaccagtttgagaattgctgtggtctgcgggaaggt
gccatcctcaccttgctgagtgacattgcctctgcacttagataccttcatgaaaacaga
atcatccatcgggatctaaagccagaaaacatcgtcctgcagcaaggagaacagaggtta
atacacaaaattattgacctaggatatgccaaggagctggatcagggcagtctttgcaca
tcattcgtggggaccctgcagtacctggccccagagctgctggagcagcagaagtacacg
gtgactgtcgactactggagctttggcaccctggccttcgagtgcatcacgggcttccgg
cccttcctccccaactggcagcctgtgcagtggcattcgaaagtccggcagaagagtgag
gtggatattgttgtcagcgaagacttgaatggaacagtgaagttttcaagctctttaccc
taccccaataatcttaacagcgtcctggctgagcgactggagaagtggctgcaactgatg
ctgatgtggcacccccgacagaggggcacagatcccacgtatgggcccaatggctgcttc
aaggccctggatgacatcttaaacttaaagctggttcatatcttgaacatggtcacaggc
accatccacacctaccctgtgacagaggacgagagtctgcagagcttgaaggccagaatc
cagcaggacacgggcatcccagaggaggaccaggagctgctgcaggaagcgggcctggca
ttgatccccgataaacctgccactcagtgtatttcagatggcaagttaaatgagggccgc
acattggacatggatcttgtttttctctttgacaacagtaaaatcacctatgagactcag
atctccccacggccccaacctgaaagtgtcagctgtatccttcaagagcccaagaggaac
ctcgccttcttccagctgaggaaggtgtggggccaggtctggcacagcatccagaccctg
aaggaggattgcaaccggctgcagcagggacagcgagccgccatgatgaatctcctccgg
aacaacagctgcctctccaagatgaagaattccatggcttccatgtctcagcagctcaag
gccaagttggatttcttcaaaaccagcatccagattgacctggagaagtacagcgagcaa
actgagtttgggatcacatcagataaactgctgctggcctggagggaaatggagcaggcc
gtggagctctgtgggcgggagaatgaagtgaaactcctggtagaacggatgatggctcta
cagacggacatcgtggacttgcagaggagccccatgggccggaagcaggggggaacgttg
gacgacctagaggagcaagcaagggagctgtacaggagactaagggaaaagcctcgagac
cagcgaactgagggtgacagtcaggaaatggtacggctgctgcttcaggcaattcagagc
ttcgagaagaaagtgcgagtgatctatacacagctcagtaaaactgtggtttgcaagcag
aaggcactggaactgttgcccaaggtggaagaggtggtgagcttaatgaatgaggatgag
aagactgttgtccggctgcaggagaagcggcagaaggagctctggaatctcctgaagatt
gcttgtagcaaggtccgtggtcctgtcagtggaagcccggatagcatgaatgcctctcga
cttagccagcctgggcagctgatgtctcagccctccacggcctccaacagcttacccgag
ccagccaagaagagtgaagaactggtggccgaagcacataacctgtgtaccctgctagaa
aatgccatacaggacaccgtgagggagcaagaccagagtttcacggccctagactggagc
tggttacagacggaagaagaagagcacaactgcctggagcaggcctcctga

KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104667046
Entry
104667046         CDS       T03989                                 

Gene name
IKBKG
Definition
(RefSeq) NF-kappa-B essential modulator isoform X1
  KO
K07210  inhibitor of nuclear factor kappa-B kinase subunit gamma
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01523  Antifolate resistance
rro04010  MAPK signaling pathway
rro04014  Ras signaling pathway
rro04062  Chemokine signaling pathway
rro04064  NF-kappa B signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04210  Apoptosis
rro04380  Osteoclast differentiation
rro04620  Toll-like receptor signaling pathway
rro04621  NOD-like receptor signaling pathway
rro04622  RIG-I-like receptor signaling pathway
rro04623  Cytosolic DNA-sensing pathway
rro04625  C-type lectin receptor signaling pathway
rro04657  IL-17 signaling pathway
rro04658  Th1 and Th2 cell differentiation
rro04659  Th17 cell differentiation
rro04660  T cell receptor signaling pathway
rro04662  B cell receptor signaling pathway
rro04668  TNF signaling pathway
rro04920  Adipocytokine signaling pathway
rro05132  Salmonella infection
rro05135  Yersinia infection
rro05142  Chagas disease
rro05145  Toxoplasmosis
rro05160  Hepatitis C
rro05161  Hepatitis B
rro05162  Measles
rro05163  Human cytomegalovirus infection
rro05164  Influenza A
rro05165  Human papillomavirus infection
rro05166  Human T-cell leukemia virus 1 infection
rro05167  Kaposi sarcoma-associated herpesvirus infection
rro05168  Herpes simplex virus 1 infection
rro05169  Epstein-Barr virus infection
rro05170  Human immunodeficiency virus 1 infection
rro05171  Coronavirus disease - COVID-19
rro05200  Pathways in cancer
rro05203  Viral carcinogenesis
rro05212  Pancreatic cancer
rro05215  Prostate cancer
rro05220  Chronic myeloid leukemia
rro05221  Acute myeloid leukemia
rro05222  Small cell lung cancer
rro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rro05340  Primary immunodeficiency
rro05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104667046 (IKBKG)
   04014 Ras signaling pathway
    104667046 (IKBKG)
   04064 NF-kappa B signaling pathway
    104667046 (IKBKG)
   04668 TNF signaling pathway
    104667046 (IKBKG)
   04151 PI3K-Akt signaling pathway
    104667046 (IKBKG)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    104667046 (IKBKG)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    104667046 (IKBKG)
   04621 NOD-like receptor signaling pathway
    104667046 (IKBKG)
   04622 RIG-I-like receptor signaling pathway
    104667046 (IKBKG)
   04623 Cytosolic DNA-sensing pathway
    104667046 (IKBKG)
   04625 C-type lectin receptor signaling pathway
    104667046 (IKBKG)
   04660 T cell receptor signaling pathway
    104667046 (IKBKG)
   04658 Th1 and Th2 cell differentiation
    104667046 (IKBKG)
   04659 Th17 cell differentiation
    104667046 (IKBKG)
   04657 IL-17 signaling pathway
    104667046 (IKBKG)
   04662 B cell receptor signaling pathway
    104667046 (IKBKG)
   04062 Chemokine signaling pathway
    104667046 (IKBKG)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    104667046 (IKBKG)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104667046 (IKBKG)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104667046 (IKBKG)
   05203 Viral carcinogenesis
    104667046 (IKBKG)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104667046 (IKBKG)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104667046 (IKBKG)
   05221 Acute myeloid leukemia
    104667046 (IKBKG)
   05220 Chronic myeloid leukemia
    104667046 (IKBKG)
   05215 Prostate cancer
    104667046 (IKBKG)
   05222 Small cell lung cancer
    104667046 (IKBKG)
  09163 Immune disease
   05340 Primary immunodeficiency
    104667046 (IKBKG)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    104667046 (IKBKG)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    104667046 (IKBKG)
   05135 Yersinia infection
    104667046 (IKBKG)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    104667046 (IKBKG)
   05170 Human immunodeficiency virus 1 infection
    104667046 (IKBKG)
   05161 Hepatitis B
    104667046 (IKBKG)
   05160 Hepatitis C
    104667046 (IKBKG)
   05171 Coronavirus disease - COVID-19
    104667046 (IKBKG)
   05164 Influenza A
    104667046 (IKBKG)
   05162 Measles
    104667046 (IKBKG)
   05168 Herpes simplex virus 1 infection
    104667046 (IKBKG)
   05163 Human cytomegalovirus infection
    104667046 (IKBKG)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104667046 (IKBKG)
   05169 Epstein-Barr virus infection
    104667046 (IKBKG)
   05165 Human papillomavirus infection
    104667046 (IKBKG)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104667046 (IKBKG)
   05142 Chagas disease
    104667046 (IKBKG)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    104667046 (IKBKG)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rro01001]
    104667046 (IKBKG)
Protein kinases [BR:rro01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   104667046 (IKBKG)
SSDB
Motif
Pfam: CC2-LZ NEMO zf_C2H2_10 Bacillus_HBL LLC1
Other DBs
NCBI-GeneID: 104667046
NCBI-ProteinID: XP_010367530
UniProt: A0A2K6ND13
LinkDB
Position
7
AA seq 419 aa
MSRHLWKSQLCEMVQPSGGPAADQDVLGEESPLGKPAMLHLPSEQGAPETLQRCLEENQE
LRDAIRQSNQMLRERCEELLHFQASQREEKEFLMCKFQEARKLVERLSLEKLNLKRQKEQ
ALREVEHLKRCQQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQTLEGRARAASEQ
ARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQE
YDNHIKSSLVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPV
LKAQADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRH
VEVSQAPLPPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE
NT seq 1260 nt   +upstreamnt  +downstreamnt
atgagcaggcacctctggaagagccaactgtgtgagatggtgcaacccagtggtggcccg
gcagcagatcaggacgtgctgggtgaagagtctcctctggggaagccagccatgctgcac
ctgccttcagagcagggcgctcctgagactctccagcgctgcctggaggagaatcaagag
ctccgagatgccatccggcagagcaaccagatgctgcgagagcgctgcgaggagcttctg
catttccaagccagccagagggaggagaaggagttcctcatgtgcaaattccaagaggcc
aggaaactggtggagagactcagcctggagaagctcaacctgaagaggcagaaagagcag
gctctgcgggaggtagagcacctgaagagatgccagcagcagatggctgaggacaaggcc
tctgtgaaagcccaggtgacatccttgctcggggagctgcaggagagccagagtcgcttg
gaggctgccactaaggaatgccagactctggagggtcgggcccgggcggccagcgagcag
gcgcggcagctggagagtgagcgcgaggcactgcagcagcagcacagcgtgcaggtggac
cagctgcgcatgcagggccagagcgtggaggccgcactccgcatggagcgccaggctgcc
tcggaggagaagcggaagctggcccagttgcaggtggcctatcaccagctcttccaagaa
tacgacaaccacatcaagagcagcctggtgggcagcgagcggaagcgaggaatgcagctg
gaagatctcaaacagcagctccagcaggctgaagaggccctggtggccaaacaggaggtg
atcgataagctgaaggaggaggccgagcagcacaagattgtgatggagaccgttccggtg
ctgaaggcccaggcggacatctacaaggcggacttccaggctgagaggcaggctcgggag
aagctggccgagaagaaggagctcttgcaggagcagctggagcagctgcagagggagtac
agcaaactgaaggccagctgtcaggagtcggccaggatcgaggacatgaggaagcggcat
gttgaggtctcccaggcccccttgccccccgcccccgcctacctctcctctcccctggcc
ctgcccagccagaggaggagcccccctgaggagccacctgacttctgctgtcccaagtgc
cagtatcaggcccctgatatggacaccctgcagatacatgtcatggagtgcattgagtag

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