KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104659017
Entry
104659017         CDS       T03989                                 

Gene name
CACNA1C
Definition
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04010  MAPK signaling pathway
rro04020  Calcium signaling pathway
rro04022  cGMP-PKG signaling pathway
rro04024  cAMP signaling pathway
rro04260  Cardiac muscle contraction
rro04261  Adrenergic signaling in cardiomyocytes
rro04270  Vascular smooth muscle contraction
rro04713  Circadian entrainment
rro04720  Long-term potentiation
rro04723  Retrograde endocannabinoid signaling
rro04724  Glutamatergic synapse
rro04725  Cholinergic synapse
rro04726  Serotonergic synapse
rro04727  GABAergic synapse
rro04728  Dopaminergic synapse
rro04742  Taste transduction
rro04911  Insulin secretion
rro04912  GnRH signaling pathway
rro04921  Oxytocin signaling pathway
rro04924  Renin secretion
rro04925  Aldosterone synthesis and secretion
rro04927  Cortisol synthesis and secretion
rro04929  GnRH secretion
rro04930  Type II diabetes mellitus
rro04934  Cushing syndrome
rro04935  Growth hormone synthesis, secretion and action
rro05010  Alzheimer disease
rro05020  Prion disease
rro05022  Pathways of neurodegeneration - multiple diseases
rro05031  Amphetamine addiction
rro05410  Hypertrophic cardiomyopathy
rro05412  Arrhythmogenic right ventricular cardiomyopathy
rro05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104659017 (CACNA1C)
   04020 Calcium signaling pathway
    104659017 (CACNA1C)
   04024 cAMP signaling pathway
    104659017 (CACNA1C)
   04022 cGMP-PKG signaling pathway
    104659017 (CACNA1C)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    104659017 (CACNA1C)
   04929 GnRH secretion
    104659017 (CACNA1C)
   04912 GnRH signaling pathway
    104659017 (CACNA1C)
   04921 Oxytocin signaling pathway
    104659017 (CACNA1C)
   04935 Growth hormone synthesis, secretion and action
    104659017 (CACNA1C)
   04924 Renin secretion
    104659017 (CACNA1C)
   04925 Aldosterone synthesis and secretion
    104659017 (CACNA1C)
   04927 Cortisol synthesis and secretion
    104659017 (CACNA1C)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    104659017 (CACNA1C)
   04261 Adrenergic signaling in cardiomyocytes
    104659017 (CACNA1C)
   04270 Vascular smooth muscle contraction
    104659017 (CACNA1C)
  09156 Nervous system
   04724 Glutamatergic synapse
    104659017 (CACNA1C)
   04727 GABAergic synapse
    104659017 (CACNA1C)
   04725 Cholinergic synapse
    104659017 (CACNA1C)
   04728 Dopaminergic synapse
    104659017 (CACNA1C)
   04726 Serotonergic synapse
    104659017 (CACNA1C)
   04720 Long-term potentiation
    104659017 (CACNA1C)
   04723 Retrograde endocannabinoid signaling
    104659017 (CACNA1C)
  09157 Sensory system
   04742 Taste transduction
    104659017 (CACNA1C)
  09159 Environmental adaptation
   04713 Circadian entrainment
    104659017 (CACNA1C)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    104659017 (CACNA1C)
   05020 Prion disease
    104659017 (CACNA1C)
   05022 Pathways of neurodegeneration - multiple diseases
    104659017 (CACNA1C)
  09165 Substance dependence
   05031 Amphetamine addiction
    104659017 (CACNA1C)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    104659017 (CACNA1C)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    104659017 (CACNA1C)
   05414 Dilated cardiomyopathy
    104659017 (CACNA1C)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    104659017 (CACNA1C)
   04934 Cushing syndrome
    104659017 (CACNA1C)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rro04040]
    104659017 (CACNA1C)
Ion channels [BR:rro04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   104659017 (CACNA1C)
SSDB
Motif
Pfam: Ion_trans CAC1F_C GPHH Ca_chan_IQ PKD_channel DUF4834
Other DBs
NCBI-GeneID: 104659017
NCBI-ProteinID: XP_030795087
LinkDB
Position
10
AA seq 2157 aa
MVNENTRMYIPEENHQGSNYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIA
YGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFR
VLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYN
QEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCI
TMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKARGD
FQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTENVA
GGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLT
IASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFVVCGGI
LETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFL
FIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYG
GPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLAR
TASPEKKQEMVEKPAVEESKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPYPNP
ETTGEEDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSSNNRFRLQCHRIVNDT
IFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKMTAYGAFLH
KGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLRPLRAINRAKGLKHVVQ
CVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQTEAECKGNYITYKDGE
VDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTEDRGPIYNYRV
EISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQRQCVEYALKARPLR
RYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQSCLFKIAMNILNMLFTG
LFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPSMNAEEN
SRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQ
VFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNS
TEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRI
WAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNA
TLFALVRTALRIKTEEGPSPSEAHQGAEDHFRPAGNLEQANEELRAIIKKIWKRTSMKLL
DQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALSLQAGLRTLHDI
GPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYYQSDGRSAFPQT
FTTQRPLHINKAGSSQGDTESPSHEKLVDSTFTPSSYSSTGSNANINNANNTALGRPPRP
AGYPSTVSTVEGHGPPLSPAIRVQEVAWKLSSNRCHSGESQAAMVGPEETSQDETYEVKM
NHDTEACSEPSLLSTEMLSYQDDENRQLTLPEEDKRDIRQSPKRGFLRSASLGRRASFHL
ECLKRQKDRGGDISQKTVLPLHLVHHQALAVAGLSPLLQRSHSPASFPRPFATPPATPGS
RGWPPQPIPTLRLEGAESSEKLNSSFPSIHCGSWAETTPGGGDSSATRRARPVSLMVPSQ
AGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDMTIEEMESAADNI
LSGGAPQSPNGALLPFVNCRDAGQDRAGGEEDAGCARARGRLSEEELQDSRIYVSSL
NT seq 6474 nt   +upstreamnt  +downstreamnt
atggtcaatgagaatacgaggatgtacattccagaggaaaaccaccaaggttccaactat
gggagcccacgccccgcccatgccaacatgaatgccaatgcggccgcgggactggcccct
gagcacatccccaccccgggggccgccctgtcctggcaggcggccattgacgcagcccgg
caggctaagctgatgggcagtgctggcaatgcgaccatctccacagtcagctccacgcag
cggaagcgacagcaatacgggaagcccaagaagcagggcagcaccacggccacacgcccg
ccccgagccctgctctgcctgaccctgaagaaccccatccggagggcctgcatcagcatt
gtcgaatggaaaccatttgaaataattattttactgactatttttgccaattgtgtggcc
ttagcgatctatattccctttccagaagatgattccaacgccactaattccaacctggaa
cgagtggaatatctctttctcataatttttacggtggaagcatttttaaaagtcatcgcc
tatggactcctctttcaccccaatgcctacctccgcaacggctggaatctgctcgatttt
atcattgtggttgtggggctttttagtgcaattttagaacaagcaaccaaagcagacggg
gcaaatgctctcggagggaaaggggccggatttgatgtgaaagcgctgagggccttccgc
gtgctgcgacccctgcggctggtgtccggagtcccaagtctccaggtggtcctgaattcc
atcatcaaggccatggtccccctgctgcacatcgccctgctcgtgctgtttgtcatcatc
atctacgccatcatcggcctggagctcttcatggggaagatgcacaagacctgctacaac
caggagggcatagcagatgttccagcagaagatgacccttccccttgtgcgctggaaaca
ggccatgggcggcagtgccagaacggcacggtgtgcaagcccggctgggatggtcccaag
cacggcatcaccaactttgacaactttgccttcgccatgctcacggtgttccagtgcatc
accatggagggctggacggacgtgctgtactgggtcaatgatgccgtaggaagggactgg
ccctggatctattttgttacactaatcatcatagggtcattttttgtacttaacttggtt
ctcggtgtgcttagcggagagttttccaaagagagggagaaggccaaggcccggggagat
ttccagaagctgcgggagaagcagcagctagaagaggatctcaaaggctacctggactgg
atcactcaggccgaagacatcgatcccgagaacgaggacgaaggcatggatgaggagaag
ccccgaaacatgagcatgcccaccagtgagaccgagtccgtcaacaccgaaaacgtggct
ggaggtgacatcgagggagaaaactgcggggccaggctggcccaccggatctccaagtca
aagttcagccgctactggcgtcggtggaatcggttctgcagaagaaagtgccgtgctgca
gtcaagtctaatgtcttctactggttggtgattttcctggtgttcctcaacacgctcacc
attgcctctgagcactacaaccagccccactggctcacagaagtccaagacacagcgaac
aaggccctgctcgccctgttcacggcagagatgctcctgaagatgtacagcctgggcctg
caggcctacttcgtgtccctcttcaaccgctttgactgcttcgtcgtgtgtggcggcatc
ctggagaccatcctggtggagaccaagatcatgtccccgctgggcatctccgtgctcaga
tgtgtccggttgctgaggatattcaagatcacgaggtactggaactccttgagcaacctg
gtggcatccttgctgaactctgtgcgctccatcgcctccctgctccttctcctcttcctc
ttcatcatcatcttctccctcctggggatgcagctctttggaggaaagttcaactttgat
gagatgcagacccggaggagcacatttgataacttcccccagtccctcctcactgtgttt
cagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatggcttatggc
ggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttcatctgtgga
aactatatcctactgaatgtgttcttggccattgctgtggacaacctggctgacgctgag
agcctcacatctgcccaaaaggaggaggaagaggagaaggagagaaagaagctggccagg
actgccagcccagagaagaaacaagagatggtagagaagccggcagtggaggaatccaag
gaggagaagattgagctgaaatccatcacggctgacggagagtctccacccactaccaag
atcaacatggatgacctccagcccaatgaaaatgaggataagagcccctaccccaaccca
gaaactacaggagaagaggatgaggaggagccagagatgcctgtcggccctcgcccacga
ccactctctgagcttcaccttaaggaaaaggcagtgcccatgccagaagccagcgcgttt
ttcatcttcagctctaacaacaggtttcgcctccagtgccaccgcattgtcaacgacacg
atcttcaccaacctgatcctcttcttcattctgctcagcagcatttccctggctgctgag
gacccggtccagcacacctccttcaggaaccatattctgttttattttgatattgttttt
accaccattttcaccattgaaattgctctgaagatgacggcttatggggcgtttctgcac
aagggctccttctgccggaactacttcaacatcctggacctgctggtggtcagcgtgtcc
ctcatctcctttggcatccagtccagtgcaatcaatgtcgtgaagatcttgcgagtcctg
cgagtactcaggcccctgagggctatcaacagggccaagggactaaagcatgtggttcag
tgtgtgtttgtcgccatccggaccatcgggaacatcgtgattgtcaccaccctgctgcag
ttcatgttcgcctgcatcggggtccagctcttcaagggaaagctgtacacctgttcagac
agttccaagcagacagaggcggaatgcaagggcaactacatcacgtacaaagacggggag
gttgaccaccccatcatccaaccccgcagctgggagaacagcaagtttgactttgacaat
gttctggcagccatgatggccctcttcaccgtctccaccttcgaagggtggccagagctg
ctgtaccgctccatcgactcccacactgaagacaggggtcccatctacaactaccgcgtg
gagatctccatcttcttcatcatctacatcatcatcatcgccttcttcatgatgaacatc
ttcgtgggcttcgtcatcgtcaccttccaggagcagggggagcaggagtacaagaactgt
gagctggacaagaaccagcgacagtgtgtggaatacgccctcaaggcccggcccctgcgg
aggtatatccccaagaaccagcaccagtacaaagtgtggtacgtggtcaactccacctat
ttcgagtacctgatgttcgtcctcatcctgctcaacaccatctgcctggccatgcagcac
tatggccagagctgcctgttcaaaattgccatgaacatcctcaacatgctcttcactggc
ctcttcaccgtggagatgatcctgaagctcattgccttcaaacccaagcactatttctgt
gatgcatggaatacatttgacgccttgattgttgtgggtagcattgttgatatagcaatc
accgaggtaaacccagctgaacatacccaatgctctccctctatgaacgcagaggaaaac
tcgcgcatctccatcaccttcttccgcctattccgggtcatgcgcctggtgaagctgctg
agccgcggggagggcatccggacgctgctgtggaccttcatcaagtccttccaggccctg
ccctatgtggccctcctgatcgtgatgctgttcttcatctacgcggtgatcgggatgcag
gtgtttgggaaaattgccctgaatgataccacagagatcaaccggaacaacaactttcag
accttcccccaggccgtgctgctcctcttcaggtgtgccaccggggaggcctggcaggac
atcatgctggcctgcatgccaggcaagaagtgtgccccggagtccgagcccagcaacagc
acggagggtgaaacaccctgtggcagcagctttgccgtcttctacttcatcagcttctac
atgctctgtgccttcctgatcatcaacctctttgtagctgtcatcatggacaactttgac
tacctgacaagggactggtccatccttggtccccaccacctggatgagtttaaaagaatc
tgggcagagtatgaccctgaagccaagggtcgtatcaaacacctggatgtggtgaccctc
ctccggcggattcagcccccactaggttttgggaagctgtgccctcaccgcgtggcttgc
aaacgcctggtctccatgaacatgcctctgaacagcgacgggacggttatgttcaatgcc
accctgtttgccctggtcaggacagccctgaggatcaaaacagaagagggacccagccca
tcagaggcccaccaaggggctgaggatcatttccgccctgcagggaacctcgaacaggcc
aatgaggagctgcgggccatcatcaagaagatctggaagcggaccagcatgaagctgctg
gaccaggtggtgccccctgcaggcgatgatgaggtcaccgttggcaagttctacgccacg
ttcctgatccaggagtacttccggaagttcaagaagcgcaaagagcagggccttgtgggc
aaaccctcccagaggaacgcgctgtctctgcaggctggcttgcgcacactgcatgacatc
gggcctgagatccgacgggccatctctggagatctcaccgctgaggaggagctggacaag
gccatgaaggaggctgtgtccgctgcttctgaagatgacatcttcaggagggccggtggc
ctgttcggcaaccacgtcagctactaccaaagcgacggccggagcgccttcccccagacc
ttcaccactcagcgcccgctgcacatcaacaaggcgggcagcagccagggcgacactgag
tcgccgtcccatgagaagctggtggactccaccttcacccccagcagctactcgtccacc
ggctccaacgccaacatcaacaacgccaacaacaccgcgctgggtcgcccccctcgcccc
gccggctaccccagcacagtcagcactgtggagggccatgggccccccttgtcccctgcc
atccgggtgcaggaggtggcgtggaagctaagctccaacaggtgccactccggggagagc
caggcagccatggtgggtccagaggagacgtctcaggatgagacctatgaagtgaagatg
aaccatgacacagaggcctgcagtgagcccagcctgctctccacagagatgctgtcctac
caggatgacgaaaatcggcaactgacgctcccagaggaggacaagagggacatccggcaa
tccccaaagaggggtttcctccgctccgcctcactaggtcgaagggcctccttccacctg
gaatgtctgaagcgacagaaggaccgagggggagacatctctcagaagacagtcctgccc
ttgcatctggttcatcatcaggcattggcagtggcaggcctgagccccctcctccagaga
agccattcccctgcctcattccccaggccttttgccaccccgccggccacacctggcagc
cgaggctggccgccacagcccatccccaccctgcggctggagggcgccgagtccagtgag
aaactcaacagcagcttcccgtccatccactgcggctcctgggctgagaccacccccggt
ggcggggacagcagcgccacccggagagcccggcccgtctccctcatggtgcccagccag
gctggggccccagggaggcagttccacggcagtgccagcagcctggtggaagcggtcttg
atttctgaaggactggggcagttcgctcaagatcccaagttcatcgaggtcaccacccag
gagctggcggacgcctgcgacatgaccatagaggagatggagagcgcggccgacaacatc
ctcagcgggggcgccccacagagccccaatggcgccctcttaccgtttgtgaactgcagg
gacgcggggcaggaccgagccgggggcgaagaggacgcgggctgtgcgcgcgcgcggggg
cgcctgagcgaggaggagctccaggacagcaggatctacgtcagcagcctgtag

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