KEGG T03989: 104671624

KEGG Orthology (KO) [BR:rro00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    104671624 (PLCG2)
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    104671624 (PLCG2)
   04014 Ras signaling pathway
    104671624 (PLCG2)
   04370 VEGF signaling pathway
    104671624 (PLCG2)
   04064 NF-kappa B signaling pathway
    104671624 (PLCG2)
   04066 HIF-1 signaling pathway
    104671624 (PLCG2)
   04020 Calcium signaling pathway
    104671624 (PLCG2)
   04070 Phosphatidylinositol signaling system
    104671624 (PLCG2)
   04072 Phospholipase D signaling pathway
    104671624 (PLCG2)
09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    104671624 (PLCG2)
   04613 Neutrophil extracellular trap formation
    104671624 (PLCG2)
   04625 C-type lectin receptor signaling pathway
    104671624 (PLCG2)
   04650 Natural killer cell mediated cytotoxicity
    104671624 (PLCG2)
   04662 B cell receptor signaling pathway
    104671624 (PLCG2)
   04664 Fc epsilon RI signaling pathway
    104671624 (PLCG2)
   04666 Fc gamma R-mediated phagocytosis
    104671624 (PLCG2)
   04670 Leukocyte transendothelial migration
    104671624 (PLCG2)
   04062 Chemokine signaling pathway
    104671624 (PLCG2)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    104671624 (PLCG2)
   04919 Thyroid hormone signaling pathway
    104671624 (PLCG2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    104671624 (PLCG2)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    104671624 (PLCG2)
  09158 Development and regeneration
   04360 Axon guidance
    104671624 (PLCG2)
   04380 Osteoclast differentiation
    104671624 (PLCG2)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104671624 (PLCG2)
   05206 MicroRNAs in cancer
    104671624 (PLCG2)
   05205 Proteoglycans in cancer
    104671624 (PLCG2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    104671624 (PLCG2)
   05214 Glioma
    104671624 (PLCG2)
   05223 Non-small cell lung cancer
    104671624 (PLCG2)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    104671624 (PLCG2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    104671624 (PLCG2)
   05171 Coronavirus disease - COVID-19
    104671624 (PLCG2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104671624 (PLCG2)
   05169 Epstein-Barr virus infection
    104671624 (PLCG2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104671624 (PLCG2)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rro04131]
    104671624 (PLCG2)
Enzymes [BR:rro01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     104671624 (PLCG2)
Membrane trafficking [BR:rro04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    104671624 (PLCG2)
Endocytosis
  Macropinocytosis
   Phospholipase C
    104671624 (PLCG2)

SSDB

Motif

Pfam:

PI-PLC-X SH2 PI-PLC-Y SH3_1 C2 SH3_9 PH SH3_2 PH_12 PH_14 EF-hand_like GDPD

Other DBs

NCBI-GeneID:

104671624

NCBI-ProteinID:

XP_010373447

UniProt:

A0A2K6RT65

LinkDB

Position

AA seq 1265 aa
MSTMVNVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGTQFVLSTLSLAADSKEDAL
NWLSGLKILHQEAMSASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLINFKVSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLSKVRERMTKFIDDTMRETAEPFLFVDEFLMYLFSRENS
IWDEKYDVVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSPEAYIRCLRMGCRCIELDC
WDGPDGKPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKT
FKEVFGDLLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEQKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTTEEEGPQDIPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTTEGGTLKYY
LTDNLTFSSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYESLSRGEAEDML
MRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKQSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSISRQKPVDLLRYNQKGLTRVYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKF
MQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILMTLTVKVLGARHLPKLGRSI
ACPFVEVEICGADYDNNKFKTTVVNDNGLSPIWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKAIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNKRLREKRVSN
SKFYS

NT seq 3798 nt +upstreamnt +downstreamnt
atgtccactatggtcaatgtggattcccttgcggaatatgagaagagccagatcaagaga
gccctggagctggggacggtgatgactgtgttcagcttccgcaagtccacccctgagcgg
aggaccgtccaggtgatcatggagacgcggcaggtggcctggagcaagaccgctgacaag
atcgagggcttcttggatatcatggaaataaaagaaatccgcccagggaagaactccaaa
gattttgaacgtgcaaaagcagttcgccagaaagaagattgctgcttcaccatcctgtat
ggcactcagttcgtcctcagcacactcagcttggcagctgactctaaagaagacgcactt
aattggctctctggcttgaaaatcttacaccaagaagcgatgagtgcgtccacacccacc
attatcgagagttggctgagaaagcagatatattctgtggatcaaaccagaagaaacagc
atcagtctccgagagttgaagaccatcttgcccctgatcaactttaaagtgagcagtgcc
aagttccttaaagataagtttgtggaaataggagcacacaaagatgagctcagctttgaa
cagttccatctcttctataaaaaacttatgtttgagcagcaaaaatcgattctcgatgaa
ttcaaaaaggattcgtccgtgttcatcctggggaacactgacaggccggatgcctccgct
gtttacctgcatgacttccagaggtttctcatacatgaacagcaggagcattgggctcag
gatctgagcaaagtccgtgagcggatgacaaagttcatcgatgacaccatgcgtgaaact
gctgagcctttcttgtttgtggatgagttcctcatgtacctgttttcacgagaaaacagc
atctgggatgagaagtatgacgtggtggacatgcaggacatgaacaaccccttgtctcat
tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagcgagtcg
tccccggaagcttacatccgctgcctgcgcatgggctgtcgctgcattgaactggactgc
tgggacgggcctgatgggaagccggtcatctaccacggctggacgcggaccaccaagatc
aagtttgatgacgtcgtacaggccatcaaagaccacgcctttgttacctcaagcttccca
gtgatcctgtccatcgaggagcactgcagcgtggagcagcagcgtcacatggccaagacc
ttcaaggaagtgtttggcgacctgctgctgatgaagcccacggaggccagcgctgaccag
ctgccctcgcccagccagctgcgggagaagatcatcatcaagcacaagaagctgggtccc
cgaggcgacgtggatgtcaacgtggaggacaagaaggatgagcagaagcaacagggagag
ctgtacatgtgggattccatcgaccagaaatggactcggcactactgcgccattgccgac
gccaagctgtccttcagtgatgacattgaacagactacggaggaggaagggccccaggat
ataccccctacagagctacattttggggagaaatggttccacaagaaggtggagaagagg
acgagtgccgagaagttgctgcaggaatactgcatggagacagggggcaaggacggcacc
ttcctggttcgggagagcgagaccttccccaatgactacaccctgtccttctggcggtca
ggccgggtccagcactgccggatccgttccaccacggagggtggaaccctgaagtactac
ctgactgacaacctcaccttcagcagcatctacgccctcatccagcactaccgcgagacg
cacctgcgctgcgccgagtttgagttgcggctcacggaccctgtgcccaaccccaacccc
cacgagtccaagccgtggtactatgagagcctgagccgcggagaggcagaggacatgctg
atgaggatcccccgggacggagccttcctgatccggaagcgagagggaagcgactcctat
gccatcaccttcagggctaggggcaaggtgaagcattgtcgcatcaaccgggatggccgg
cactttgtgctggggacctctgcctattttgagagtctggtggagctcgtcagttactac
gagaagcattcactctaccgaaagatgagactgcgctatcccgtgacccccgagctcctg
gagcgctacaacatggaaagagatataaactccctctacgatgtcagcagaatgtatgtg
gatcccagtgaaatcaatccgtccatgcctcagagaaccgtgaaagctctgtatgactac
aaagccaagcaaagcgatgagctgagcttctgccgcggtgccctcatccacaatgtctcc
aaggagcccgggggctggtggaaaggagactatggaaccaggatccagcagtacttccca
tccaactacgtcgaggacatctcaactgcagatgttgaggagctggaaaaacagattatt
gaagacaatcccttagggtctctttgcagaggaatattggacctcaacacctataacgtc
gtgaaagccccacagggaaaaaaccagaagccctttgtctttatcctggagcccaagaag
cagggcgaccctccggtggagtttgccacagacagggtggaggagctcttcgagtggttt
cagagcatccgagagatcacctggaagattgacaccaaggagaacaacatgaagtactgg
gagaagaaccagtccatcgccatcgagctctctgatctggtggtctactgcaaaccaacc
agcaaaaccaaggacaacttagaaaatcctgacttccgagaaatccgctcctttgtggag
acgaaggctgacagcatcagcaggcagaagcccgtcgacctcctgaggtacaatcaaaag
ggcctgacccgcgtctacccaaagggacaaagagttgactcttcaaactacgaccccttc
cgcctctggctgtgcggttctcagatggtggcactcaatttccagacggcagataagttc
atgcagatgaatcacgcgctgttttctctcaatgggcgcacgggctacgttctgcagcct
gagagcatgaggacagagaaatatgacccaatgccacccgagtcccagaggaagatcctg
atgacgctgacggtcaaggttctcggtgctcgccatctccccaaacttggacgaagtatt
gcctgtccctttgtagaggtagagatctgtggcgccgactatgacaacaacaagttcaag
acgacggttgtgaatgataatggcctcagccctatctgggctccaacacaggagaaggtg
acatttgaaatttatgacccaaacctggcatttctgcgctttgtggtttacgaagaagat
atgttcagtgatcccaactttcttgctcatgccacttaccccattaaagcaatcaaatca
ggattcaggtctgttcctctgaagaatgggtacagcgaggacatagagctggcttccctc
ctggttttctgtgagatgcggccagtcctggagagcgaagaggaactttactcctcctgt
cgccagctaaggaggcggcaagaagaactgaacaaccagctctttctgtatgacacacac
cagaacttgcgcaatgccaaccgggatgccctggttaaagagttcaatgttaatgagaac
cagctccagctgtaccaggagaaatgcaacaagaggttaagagagaagagagtcagcaac
agcaagttttactcatag

Rhinopithecus roxellana (golden snub-nosed monkey): 104672220

Entry

104672220 CDS T03989

Gene name

PLCG1

Definition

(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

K01116

phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]

Organism

rro Rhinopithecus roxellana (golden snub-nosed monkey)

Pathway

rro00562

Inositol phosphate metabolism

rro01100

Metabolic pathways

rro01521

EGFR tyrosine kinase inhibitor resistance

rro04012

ErbB signaling pathway

rro04014

Ras signaling pathway

rro04015

Rap1 signaling pathway

rro04020

Calcium signaling pathway

rro04062

Chemokine signaling pathway

rro04064

NF-kappa B signaling pathway

rro04066

HIF-1 signaling pathway

rro04070

Phosphatidylinositol signaling system

rro04072

Phospholipase D signaling pathway

rro04360

Axon guidance

rro04370

VEGF signaling pathway

rro04613

Neutrophil extracellular trap formation

rro04650

Natural killer cell mediated cytotoxicity

rro04658

Th1 and Th2 cell differentiation

rro04659

Th17 cell differentiation

rro04660

T cell receptor signaling pathway

rro04664

Fc epsilon RI signaling pathway

rro04666

Fc gamma R-mediated phagocytosis

rro04670

Leukocyte transendothelial migration

rro04722

Neurotrophin signaling pathway

rro04750

Inflammatory mediator regulation of TRP channels

rro04919

Thyroid hormone signaling pathway

rro04933

AGE-RAGE signaling pathway in diabetic complications

rro04935

Growth hormone synthesis, secretion and action

rro05012

Parkinson disease

rro05022

Pathways of neurodegeneration - multiple diseases

rro05135

Yersinia infection

rro05167

Kaposi sarcoma-associated herpesvirus infection

rro05170

Human immunodeficiency virus 1 infection

rro05171

Coronavirus disease - COVID-19

rro05200

Pathways in cancer

rro05205

Proteoglycans in cancer

rro05206

MicroRNAs in cancer

rro05214

Glioma

rro05223

Non-small cell lung cancer

rro05225

Hepatocellular carcinoma

rro05231

Choline metabolism in cancer

rro05235

PD-L1 expression and PD-1 checkpoint pathway in cancer

Module

rro_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Brite

KEGG Orthology (KO) [BR:rro00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    104672220 (PLCG1)
09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    104672220 (PLCG1)
   04014 Ras signaling pathway
    104672220 (PLCG1)
   04015 Rap1 signaling pathway
    104672220 (PLCG1)
   04370 VEGF signaling pathway
    104672220 (PLCG1)
   04064 NF-kappa B signaling pathway
    104672220 (PLCG1)
   04066 HIF-1 signaling pathway
    104672220 (PLCG1)
   04020 Calcium signaling pathway
    104672220 (PLCG1)
   04070 Phosphatidylinositol signaling system
    104672220 (PLCG1)
   04072 Phospholipase D signaling pathway
    104672220 (PLCG1)
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    104672220 (PLCG1)
   04650 Natural killer cell mediated cytotoxicity
    104672220 (PLCG1)
   04660 T cell receptor signaling pathway
    104672220 (PLCG1)
   04658 Th1 and Th2 cell differentiation
    104672220 (PLCG1)
   04659 Th17 cell differentiation
    104672220 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    104672220 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    104672220 (PLCG1)
   04670 Leukocyte transendothelial migration
    104672220 (PLCG1)
   04062 Chemokine signaling pathway
    104672220 (PLCG1)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    104672220 (PLCG1)
   04919 Thyroid hormone signaling pathway
    104672220 (PLCG1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    104672220 (PLCG1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    104672220 (PLCG1)
  09158 Development and regeneration
   04360 Axon guidance
    104672220 (PLCG1)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104672220 (PLCG1)
   05206 MicroRNAs in cancer
    104672220 (PLCG1)
   05205 Proteoglycans in cancer
    104672220 (PLCG1)
   05231 Choline metabolism in cancer
    104672220 (PLCG1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104672220 (PLCG1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    104672220 (PLCG1)
   05214 Glioma
    104672220 (PLCG1)
   05223 Non-small cell lung cancer
    104672220 (PLCG1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    104672220 (PLCG1)
   05022 Pathways of neurodegeneration - multiple diseases
    104672220 (PLCG1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    104672220 (PLCG1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    104672220 (PLCG1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    104672220 (PLCG1)
   05171 Coronavirus disease - COVID-19
    104672220 (PLCG1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104672220 (PLCG1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104672220 (PLCG1)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rro04131]
    104672220 (PLCG1)
Enzymes [BR:rro01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     104672220 (PLCG1)
Membrane trafficking [BR:rro04131]
Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    104672220 (PLCG1)
Endocytosis
  Macropinocytosis
   Phospholipase C
    104672220 (PLCG1)

SSDB

Motif

Pfam:

PI-PLC-X SH2 PI-PLC-Y C2 SH3_1 PH SH3_9 SH3_2 PH_12 GDPD PH_9

Other DBs

NCBI-GeneID:

104672220

NCBI-ProteinID:

XP_010374254

UniProt:

A0A2K6Q7Y9

LinkDB

Position

AA seq 1291 aa
MAGAASPCANGCGPGAPSDAEVLHLCRSLEVGTVMTLFYSKKSQRPERKTFQVKLETRQI
TWSRGADKIEGAIDIREIKEIRPGKTSRDFDRYQEDPAFRPDQSHCFVILYGMEFRLKTL
SLQATSEDEVNMWIKGLTWLMEDTLQAPTPLQIERWLRKQFYSVDRNREDRISAKDLKNM
LSQVNYRVPNMRFLRERLTDLEQRSGDITYGQFAQLYRSLMYSAQKTMDLPFLEASTLRA
GERPELCRVSLPEFQQFLLDYQGELWAVDRLQVQEFMLSFLRDPLREIEEPYFFLDEFVT
FLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEAYARCLRMG
CRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLQTIKEHAFVASEYPVILSIEDHCSIA
QQRNMAQHFKKVLGDTLLTKPVEISADGLPSPNQLKRKILIKHKKLAEGSAYEEVPTSMM
YSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETSSDQGNEDEEEPKEVSS
STELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFVGDYTLSFW
RNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMRLSEPVPQT
NAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQE
GQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYGALYEGRNP
GFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGDYGGKKQLW
FPSNYVEEMVNPVALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNNRLFVFSIS
MASVAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKIMERRKKIALELSELVVYC
RPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIYPKGQRLDS
SNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMTGRHCGYVLQPSTMRDEAFDPFDKS
SLRGLEPCAISVEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVVDNGLNPVW
PAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATYPVKGLKTGYRAVPLKNNYSEDL
ELASLLIKIDIFPAKQENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFESRYQQPFED
FRISQEHLADHFDSRERRAPRRTRVNGDNRL

NT seq 3876 nt +upstreamnt +downstreamnt
atggcgggcgccgcgtccccctgcgccaacggctgcgggcccggcgcgccctcggacgcc
gaggtgctgcacctctgccgcagcctcgaggtgggcaccgtcatgactttgttctactcc
aagaagtcgcagcgacccgagcggaagaccttccaggtcaagctggagacgcgccagatc
acgtggagccggggcgccgacaagatagagggggccattgatattcgtgaaatcaaggag
atccgcccagggaagacctcacgggactttgatcgctatcaagaggaccccgctttccgg
ccggaccagtcacactgctttgtcattctctatggaatggaattccgcctgaagacgctg
agcctgcaagccacatctgaggatgaagtgaacatgtggatcaagggcttaacttggctg
atggaggatactttgcaggcacccacacccctgcagattgagaggtggctccggaagcag
ttttactcagtggatcggaatcgtgaggatcgtatatcagccaaggacctaaagaacatg
ctgtcccaggtcaactaccgggtccccaacatgcgcttcctccgagagcggctgacggac
ctggagcagcgcagcggggacatcacctacgggcagtttgctcagctgtaccgcagcctc
atgtacagcgcccagaagacgatggacctccccttcttggaagccagtactctgagggct
ggggagcggccggagctttgccgagtgtcccttcctgagttccagcagttccttcttgac
taccagggggagctgtgggctgttgatcgcctccaggtgcaggagttcatgctcagcttc
ctccgagaccccttgcgagagatcgaggagccatacttcttcctggatgagtttgtcacc
ttcctgttctccaaagagaatagtgtgtggaactcgcagctggatgcagtatgcccggac
accatgaacaaccccctttcccactattggatctcttcctcacacaacacgtacctgacc
ggggaccagttctccagtgagtcctccttggaagcctatgctcgctgcctgcggatgggc
tgtcgctgcattgagttggactgctgggacggcccagatgggatgccagttatttaccat
gggcacacccttaccaccaagatcaagttctcagatgtcctgcaaaccatcaaggagcat
gcctttgtggcctcagagtacccagtcatcctgtccattgaggaccactgcagcattgcc
cagcagaggaacatggcccagcacttcaagaaggtgctaggggacacactcctcaccaag
cccgtggagatctccgctgatgggctcccctcacccaaccagcttaagaggaagatcctc
atcaagcacaagaagctggcggagggcagtgcctacgaggaggtgcctacatccatgatg
tactctgagaacgacatcagcaactccatcaagaatggcatcctctacctggaggaccct
gtgaaccacgaatggtatccccactacttcgttctgaccagcagcaagatctactactct
gaggagaccagcagtgaccagggcaacgaggatgaggaggagcccaaggaggtcagcagc
agcacagagctgcactccaatgagaagtggttccatgggaagctaggggcagggcgtgac
gggcggcacatcgctgagcgcctgctcactgagtactgcatcgagaccggggcccctgac
ggctccttcctcgtgcgagagagtgagaccttcgtgggcgactacacgctctctttctgg
cggaatgggaaagtccagcactgccgtatccactcacggcaagatgctgggacccccaag
ttcttcttgacagacaacctcgtctttgactccctctatgacctcatcacacactaccag
caggtgcctctgcgctgcaatgagtttgagatgcgactttcagagcctgtcccacagacg
aatgcccacgagagcaaagagtggtaccacgcgagcctgaccagagcacaggctgagcac
atgctgatgcgtgtccctcgtgatggggccttcctggtgcggaagcggaatgagcccaac
tcatatgccatctctttccgggctgaaggcaagatcaagcattgccgtgtccagcaagag
ggccagactgtgatgctagggaactcggagttcgacagccttgttgacctcatcagctac
tatgagaagcacccgctataccgcaagatgaaactgcgctatcccatcaacgaggaggcg
ctggagaagattggcacagctgagcctgactacggggccctgtatgagggacgcaaccct
ggcttctatgtagaggcaaaccctatgccaactttcaagtgtgcagtcaaagctctcttt
gactacaaggcccagagagaggatgagctgaccttcaccaagagcgccatcatccagaat
gtggagaagcaagagggaggctggtggcgaggggactacggagggaagaagcagctgtgg
ttcccatcaaactacgtggaagagatggtcaaccccgtggccctggagccagagagggag
cacttggacgagaacagccccctaggggacttgctgcggggggtcttggatgtgccggct
tgtcagattgccatccgtcctgagggcaagaacaaccggctcttcgtcttctccatcagc
atggcgtcggtggcccactggtccctggatgttgctgctgactcacaggaggagctgcag
gactgggtgaaaaagatccgtgaagtggcccagaccgcagatgccaggctcactgaaggg
aagataatggaacggaggaagaagatcgccctggagctctctgaacttgttgtctactgc
cggcctgttcccttcgatgaagagaagattggcacagaacgtgcttgctaccgggacatg
tcatccttcccggaaaccaaggctgagaaatacgtgaacaaggccaaaggcaagaagttc
cttcagtacaatcgactgcagctctcccgcatctaccccaagggccagcgactggattcc
tccaactacgatcctttgcccatgtggatctgtggcagtcagctggtggccctcaacttc
cagacccctgacaagcctatgcagatgaaccaggctctcttcatgacgggcaggcactgt
ggctacgtgctgcagccaagcaccatgcgggatgaggccttcgacccctttgacaagagc
agcctccgcgggctggagccatgtgccatctctgttgaggtgctgggtgccagacatttg
ccaaagaatggccgaggcattgtgtgcccttttgtggagattgaggtggctggagctgag
tatgacagcaccaagcagaagacagagtttgtggtggacaatggactcaaccctgtatgg
ccggccaagcccttccacttccagatcagtaaccctgaatttgcctttctgcgctttgtg
gtgtatgaggaagacatgtttagtgaccagaatttcctggctcaggctacttacccggta
aaaggcctgaagacaggatacagagcagtgcctttgaagaacaactacagtgaggacctg
gagttggcctccctgctgatcaagattgacattttccctgccaagcaggagaatggtgac
ctcagtcccttcagtggtacgtccctgcgggagcggggctcagatgcctcaggccagctg
tttcacggccgagcccgggaaggctcctttgaatcccgctaccagcagccatttgaggac
ttccgcatctcccaggagcatcttgcagaccattttgacagtcgagaacgaagggcccca
agaaggactcgggtcaatggagacaaccgcctctag

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