Rhinopithecus roxellana (golden snub-nosed monkey): 104679749
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Entry
104679749 CDS
T03989
Gene name
PTK2
Definition
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01522
Endocrine resistance
rro04012
ErbB signaling pathway
rro04062
Chemokine signaling pathway
rro04151
PI3K-Akt signaling pathway
rro04360
Axon guidance
rro04370
VEGF signaling pathway
rro04510
Focal adhesion
rro04670
Leukocyte transendothelial migration
rro04810
Regulation of actin cytoskeleton
rro04935
Growth hormone synthesis, secretion and action
rro05100
Bacterial invasion of epithelial cells
rro05135
Yersinia infection
rro05146
Amoebiasis
rro05163
Human cytomegalovirus infection
rro05165
Human papillomavirus infection
rro05170
Human immunodeficiency virus 1 infection
rro05200
Pathways in cancer
rro05202
Transcriptional misregulation in cancer
rro05205
Proteoglycans in cancer
rro05222
Small cell lung cancer
rro05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
104679749 (PTK2)
04370 VEGF signaling pathway
104679749 (PTK2)
04151 PI3K-Akt signaling pathway
104679749 (PTK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
104679749 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
104679749 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
104679749 (PTK2)
04062 Chemokine signaling pathway
104679749 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
104679749 (PTK2)
09158 Development and regeneration
04360 Axon guidance
104679749 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104679749 (PTK2)
05202 Transcriptional misregulation in cancer
104679749 (PTK2)
05205 Proteoglycans in cancer
104679749 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
104679749 (PTK2)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
104679749 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
104679749 (PTK2)
05100 Bacterial invasion of epithelial cells
104679749 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
104679749 (PTK2)
05163 Human cytomegalovirus infection
104679749 (PTK2)
05165 Human papillomavirus infection
104679749 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
104679749 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
104679749 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rro01001
]
104679749 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
rro01009
]
104679749 (PTK2)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
104679749 (PTK2)
Protein kinases [BR:
rro01001
]
Non-receptor tyrosine kinases
FAK family
104679749 (PTK2)
Protein phosphatases and associated proteins [BR:
rro01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
104679749 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_N_2
FERM_M
Kinase-like
FERM_F2
Motif
Other DBs
NCBI-GeneID:
104679749
NCBI-ProteinID:
XP_030793268
LinkDB
All DBs
Position
9
AA seq
1105 aa
AA seq
DB search
MLLELAGQEALKPAGAIYMEKSGCSPFPVCWAKEYDRYLASSKIMAAAYLDPNLNHTPNS
STKTHLGTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGASQSFIIRPQKEGERALPSIPKL
ANSEKQGMRTHTVSVSDEISGDETDDYAEIIDEEDTYTMPSTRDYEIQRERIELGRCIGE
GQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVI
TENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAAR
NVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGV
CMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFT
ELKAQLSTILEEEKAQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFY
PSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQTSLLDQTDSWNHRPQEIAMWQPNVED
STALDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGS
LQGPIGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLSSPADSYNEGVKPWRLQPQ
EISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLAT
VDETIPLLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHAL
AVDAKNLLDVIDQARLKMLGQTRPH
NT seq
3318 nt
NT seq
+upstream
nt +downstream
nt
atgttgttggaactggcaggccaagaggccctgaaaccagcaggtgccatctatatggag
aaaagcggctgtagtccatttccggtgtgttgggctaaagaatatgacagatacctagca
tctagcaaaataatggcagctgcttaccttgaccccaacttgaatcacacgccaaattcg
agtactaagactcacctgggtactggtatggaacgttctcctggtgcgatggagcgagta
ttaaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcatgtggcctgctatggattccgcctcagtcacctgcggtcagaggaggttcac
tggcttcacgtggatatgggcgtctccagtgtgagggagaagtatgagcttgcccaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagataagccaactttgaatttcttctatcaacaggtgaagagcgattatatg
ttagagatagctgatcaagtggaccaggaaattgctttgaagttgggttgtctagaaata
cggcgatcatactgggagatgcggggcaatgcactagaaaagaagtctaactatgaagta
ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaacactaagaaaattgatccaacaaacatttagacaattcgccaaccttaataga
gaagaaagtattctgaaattctttgagatcctgtctccagtctacagatttgataaggaa
tgcttcaagtgtgctcttggttcaagctggattatttcagtggaattggcaatcggccca
gaagaagggatcagttacttgacggacaagggctgcaatcccacacatcttgctgacttt
actcaagtgcagaccattcagtattcaaacagtgaagataaggacagaaaaggaatgcta
caactaaaaatagcaggtgcacctgagcctctgacagtgacggcaccatccctaaccatt
gcggagaatatggctgacctgatagatgggtattgccggctggtgaatggagcctcgcag
tcatttatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagttg
gccaacagcgaaaagcaaggcatgcggacacacaccgtctctgtgtcagatgaaattagt
ggggacgaaacagatgattatgctgagattatagatgaagaagatacttacaccatgccc
tcaaccagggattatgagattcaaagagaaagaatagaacttggacgatgtattggagaa
ggccaatttggagatgtacatcaaggcgtttatatgagtccagagaatccagctttggcg
gttgcaattaaaacatgtaaaaactgtacttcggacagcgtgagagagaaatttcttcaa
gaagccttaacaatgcgtcagtttgaccatcctcatattgtgaagctgattggagtcatc
acagagaatcctgtctggataatcatggagctgtgcacacttggagagctgaggtcattt
ttgcaagtaaggaaatacagtttggatctagcatctttgatcttgtatgcctatcagctt
agtacagctcttgcatatctagagagcaaaagatttgtacacagggacattgctgctcgg
aatgttctggtgtcctcaaatgattgtgtaaagttaggagactttggattatcccgatat
atggaagatagtacttactacaaagcttccaaaggaaaattgcctattaaatggatggct
ccagagtcaatcaattttcgacgttttacctcagctagtgacgtatggatgtttggtgtg
tgtatgtgggagatactgatgcatggtgtgaagccttttcaaggagtgaagaacaatgat
gtgatcggtcgaattgaaaatggggaaagattaccaatgcctccaaattgtcctcctacc
ctctacagccttatgacgaaatgctgggcctatgaccccagcaggcggcccaggtttact
gaacttaaagctcagctcagcacaatcctggaggaagagaaggctcagcaagaagaacgc
atgaggatggagtccagaagacaggccacagtgtcctgggactccggagggtctgatgaa
gcgccacccaagcccagcagaccgggttatcctagtccgaggtccagcgaaggattttat
cccagcccacagcacatggtacaaaccaatcattaccaggtttctggctaccctggttca
catggaatcacagccatggctggcagcatctatccaggtcagacatctcttttggaccaa
acagattcatggaatcatagacctcaggagatagcaatgtggcagcccaatgtggaggac
tctacagcattggacctgcgagggattgggcaagtgttgccaacccacctgatggaagag
cggctaatccgacaacaacaggaaatggaagaagatcagcgctggctggaaaaagaggaa
agatttctgaaacctgatgtgagactctctcgaggcagtattgacagggaggatggaagt
cttcagggtccgattggaaaccaacatatatatcagcctgtgggtaaaccagatcctgca
gctccaccaaagaaaccgcctcgccctggagctcccggtcacctgggaagccttgccagc
ctcagcagccctgctgacagctacaacgagggtgtcaagccatggaggcttcagccccag
gaaatcagcccccctcctactgccaacctggaccggtcaaatgataaggtgtacgagaat
gtgacgggcctggtgaaagctgtcatcgagatgtccagtaaaatccagccagccccacca
gaggagtatgtccctatggtgaaggaagtcggcttggccctgaggacgttattggccact
gtggatgagaccattcccctcctaccagccagcacccaccgagagattgagatggcacag
aaactattgaactctgacctgggtgagctcatcaacaagatgaaactggcccagcagtat
gtcatgaccagtctccagcaagagtacaaaaagcaaatgctgactgctgctcacgccctg
gctgtggatgccaaaaacttactcgatgtcattgaccaagcaagactgaaaatgcttggg
cagacgagaccacactga
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integrated database retrieval system
