KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104680286Help
Entry
104680286         CDS       T03989                                 

Gene name
STAT3
Definition
(RefSeq) signal transducer and activator of transcription 3
  KO
K04692  signal transducer and activator of transcription 3
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01521  EGFR tyrosine kinase inhibitor resistance
rro04062  Chemokine signaling pathway
rro04066  HIF-1 signaling pathway
rro04068  FoxO signaling pathway
rro04217  Necroptosis
rro04550  Signaling pathways regulating pluripotency of stem cells
rro04630  Jak-STAT signaling pathway
rro04659  Th17 cell differentiation
rro04917  Prolactin signaling pathway
rro04920  Adipocytokine signaling pathway
rro04931  Insulin resistance
rro04933  AGE-RAGE signaling pathway in diabetic complications
rro05145  Toxoplasmosis
rro05160  Hepatitis C
rro05161  Hepatitis B
rro05162  Measles
rro05163  Human cytomegalovirus infection
rro05167  Kaposi sarcoma-associated herpesvirus infection
rro05169  Epstein-Barr virus infection
rro05200  Pathways in cancer
rro05203  Viral carcinogenesis
rro05205  Proteoglycans in cancer
rro05206  MicroRNAs in cancer
rro05212  Pancreatic cancer
rro05221  Acute myeloid leukemia
rro05223  Non-small cell lung cancer
rro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
rro05321  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 Jak-STAT signaling pathway
    104680286 (STAT3)
   04066 HIF-1 signaling pathway
    104680286 (STAT3)
   04068 FoxO signaling pathway
    104680286 (STAT3)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    104680286 (STAT3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    104680286 (STAT3)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    104680286 (STAT3)
   04062 Chemokine signaling pathway
    104680286 (STAT3)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    104680286 (STAT3)
   04917 Prolactin signaling pathway
    104680286 (STAT3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104680286 (STAT3)
   05206 MicroRNAs in cancer
    104680286 (STAT3)
   05205 Proteoglycans in cancer
    104680286 (STAT3)
   05203 Viral carcinogenesis
    104680286 (STAT3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    104680286 (STAT3)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    104680286 (STAT3)
   05221 Acute myeloid leukemia
    104680286 (STAT3)
   05223 Non-small cell lung cancer
    104680286 (STAT3)
  09163 Immune disease
   05321 Inflammatory bowel disease (IBD)
    104680286 (STAT3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    104680286 (STAT3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    104680286 (STAT3)
  09172 Infectious disease: viral
   05162 Measles
    104680286 (STAT3)
   05161 Hepatitis B
    104680286 (STAT3)
   05160 Hepatitis C
    104680286 (STAT3)
   05163 Human cytomegalovirus infection
    104680286 (STAT3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    104680286 (STAT3)
   05169 Epstein-Barr virus infection
    104680286 (STAT3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    104680286 (STAT3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104680286 (STAT3)
Transcription factors [BR:rro03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    104680286 (STAT3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: STAT_alpha STAT_int STAT_bind SH2 E2R135 Fib_alpha
Motif
Other DBs
NCBI-GeneID: 104680286
NCBI-ProteinID: XP_010384484
LinkDB All DBs
Position
Un
AA seq 864 aa AA seqDB search
MTACLGQAGAGRGLAEGAVIQRFPELRRRRPGGGAGGSDVAAEGTSPNRILDRHPGSALS
LPLGSEKPFGLREPRRPPPAHAQPRPLGLCWRNSRMAQWNQLQQLDTRYLEQLHQLYSDS
FPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRR
IKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLE
QHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQ
MLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLEN
WITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVER
QPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFN
ILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEV
YHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVA
EVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWL
DNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVE
KDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGK
YCRPESQEHPEADPGAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEP
SAGGQFESLTFDMELTSECATSPM
NT seq 2595 nt NT seq  +upstreamnt  +downstreamnt
atgacggcgtgcctcggccaggctggggctgggcggggattggctgaaggggctgtaatt
cagcggtttccggagctgcggcggcgtagacccggagggggagccgggggttccgacgtc
gcagccgagggaacaagccccaaccggatcctggacaggcaccccggctcggcgctgtct
ctccccctcggctcggagaagcccttcggcctgagggagccccgccgcccgcccccggcg
cacgcgcagccccggcctctcggcctctgctggagaaacagcaggatggcccaatggaat
cagctacagcagcttgacacacggtacctggagcagctccatcagctctacagtgacagc
ttcccaatggagctgcggcagtttctggccccttggattgagagtcaagattgggcatat
gcggccagcaaagaatcacatgccactttggtgtttcataatctccttggcgagattgac
cagcagtatagccgcttcctgcaagagtcgaatgttctctatcagcacaatctacgaaga
atcaagcagtttcttcagagcaggtatcttgagaagccaatggagattgcccggattgtg
gcccggtgcctgtgggaagagtcacgcctcctacagactgcagccactgcggcccagcaa
gggggccaggccaaccaccccacagcagctgtggtgacggagaagcagcagatgctggag
cagcaccttcaggatgtccggaagagagtgcaggatctagaacagaaaatgaaagtggta
gagaatctccaggatgactttgatttcaactataaaaccctcaagagtcaaggagacatg
caagatctgaatggaaacaaccagtcagtgaccaggcagaagatgcagcagctggaacag
atgctcactgcgctggaccagatgcggagaagcatcgtgagtgagctggcggggcttttg
tcagcgatggagtacgtgcagaaaactctcacagacgaggagctggctgactggaagagg
cggcaacagattgcctgcattggaggtccgcccaacatctgcctagatcggctagaaaac
tggataacgtcattagcagaatctcaacttcagacccgtcaacaaattaagaaactggag
gagttgcagcaaaaagtttcctacaaaggggaccccattgtacagcaccggccgatgctg
gaggagagaattgtggagctattcagaaacttaatgaaaagtgcctttgtggtggagcgg
cagccttgcatgcccatgcatcccgaccggcccctcgtcatcaagactggagtccagttc
actaccaaagtcaggttactggtcaaattccctgagttaaattatcagcttaaaattaaa
gtgtgcattgacaaagactctggggatgttgcagctctcagaggatcccggaaatttaac
attctgggcacaaacacaaaagtgatgaacatggaagagtccaacaacggcagcctctct
gcagaattcaaacacttgaccctgagggagcagagatgtgggaatgggggccgagccaat
tgtgatgcttccctgattgtgactgaagagctgcacctgatcacctttgagacagaggtg
tatcaccaaggcctcaagattgacctagagacacactccttgccagttgtggtgatctcc
aacatctgtcagatgccaaatgcctgggcgtccatcctgtggtacaacatgctgaccaac
aatcccaagaacgtaaacttttttaccaagcccccaatcggaacctgggatcaagtggcc
gaggtcctgagctggcagttctcctccaccaccaagcgaggactgagcatcgagcagctg
actacactggcagagaaactcttgggacctggcgtgaattattcagggtgtcagatcaca
tgggctaaattttgcaaagaaaacatggctggcaagggcttctccttctgggtctggctg
gacaatatcattgaccttgtgaaaaagtacatcctggccctttggaacgaagggtacatc
atgggctttatcagtaaggaacgggagcgggccatcttgagcaccaagcctccaggcacc
tttctgctaagattcagtgaaagcagcaaagaaggcggcgtcactttcacttgggtggag
aaggacatcagcggtaagacccagatccagtccgtggaaccatacaccaagcagcagttg
aacaacatgtcatttgctgaaatcatcatgggctataagatcatggatgctaccaatatt
ctggtgtctccgctggtctatctctaccctgacattcccaaggaggaggcatttggaaag
tattgtcggccagagagccaggagcatcctgaagctgacccaggcgccgccccatacctg
aagaccaagtttatctgtgtgacaccaacgacctgcagcaataccattgacctgccgatg
tccccccgcactttagattcattgatgcagtttggaaataatggtgaaggtgctgaaccc
tcagcaggagggcagtttgagtccctcacctttgacatggagttgacctcggagtgtgct
acctcccccatgtga

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