KEGG   Rhinopithecus roxellana (golden snub-nosed monkey): 104681311
Entry
104681311         CDS       T03989                                 

Gene name
GRB2
Definition
(RefSeq) growth factor receptor-bound protein 2
  KO
K04364  growth factor receptor-bound protein 2
Organism
rro  Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro01521  EGFR tyrosine kinase inhibitor resistance
rro01522  Endocrine resistance
rro04010  MAPK signaling pathway
rro04012  ErbB signaling pathway
rro04014  Ras signaling pathway
rro04062  Chemokine signaling pathway
rro04068  FoxO signaling pathway
rro04072  Phospholipase D signaling pathway
rro04150  mTOR signaling pathway
rro04151  PI3K-Akt signaling pathway
rro04380  Osteoclast differentiation
rro04510  Focal adhesion
rro04540  Gap junction
rro04550  Signaling pathways regulating pluripotency of stem cells
rro04630  JAK-STAT signaling pathway
rro04650  Natural killer cell mediated cytotoxicity
rro04660  T cell receptor signaling pathway
rro04662  B cell receptor signaling pathway
rro04664  Fc epsilon RI signaling pathway
rro04714  Thermogenesis
rro04722  Neurotrophin signaling pathway
rro04910  Insulin signaling pathway
rro04912  GnRH signaling pathway
rro04915  Estrogen signaling pathway
rro04917  Prolactin signaling pathway
rro04926  Relaxin signaling pathway
rro04935  Growth hormone synthesis, secretion and action
rro05034  Alcoholism
rro05160  Hepatitis C
rro05161  Hepatitis B
rro05163  Human cytomegalovirus infection
rro05165  Human papillomavirus infection
rro05200  Pathways in cancer
rro05203  Viral carcinogenesis
rro05205  Proteoglycans in cancer
rro05206  MicroRNAs in cancer
rro05210  Colorectal cancer
rro05211  Renal cell carcinoma
rro05213  Endometrial cancer
rro05214  Glioma
rro05215  Prostate cancer
rro05220  Chronic myeloid leukemia
rro05221  Acute myeloid leukemia
rro05223  Non-small cell lung cancer
rro05224  Breast cancer
rro05225  Hepatocellular carcinoma
rro05226  Gastric cancer
rro05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:rro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    104681311 (GRB2)
   04012 ErbB signaling pathway
    104681311 (GRB2)
   04014 Ras signaling pathway
    104681311 (GRB2)
   04630 JAK-STAT signaling pathway
    104681311 (GRB2)
   04068 FoxO signaling pathway
    104681311 (GRB2)
   04072 Phospholipase D signaling pathway
    104681311 (GRB2)
   04151 PI3K-Akt signaling pathway
    104681311 (GRB2)
   04150 mTOR signaling pathway
    104681311 (GRB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    104681311 (GRB2)
   04540 Gap junction
    104681311 (GRB2)
   04550 Signaling pathways regulating pluripotency of stem cells
    104681311 (GRB2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    104681311 (GRB2)
   04660 T cell receptor signaling pathway
    104681311 (GRB2)
   04662 B cell receptor signaling pathway
    104681311 (GRB2)
   04664 Fc epsilon RI signaling pathway
    104681311 (GRB2)
   04062 Chemokine signaling pathway
    104681311 (GRB2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    104681311 (GRB2)
   04912 GnRH signaling pathway
    104681311 (GRB2)
   04915 Estrogen signaling pathway
    104681311 (GRB2)
   04917 Prolactin signaling pathway
    104681311 (GRB2)
   04926 Relaxin signaling pathway
    104681311 (GRB2)
   04935 Growth hormone synthesis, secretion and action
    104681311 (GRB2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    104681311 (GRB2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    104681311 (GRB2)
  09159 Environmental adaptation
   04714 Thermogenesis
    104681311 (GRB2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    104681311 (GRB2)
   05206 MicroRNAs in cancer
    104681311 (GRB2)
   05205 Proteoglycans in cancer
    104681311 (GRB2)
   05203 Viral carcinogenesis
    104681311 (GRB2)
   05231 Choline metabolism in cancer
    104681311 (GRB2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    104681311 (GRB2)
   05225 Hepatocellular carcinoma
    104681311 (GRB2)
   05226 Gastric cancer
    104681311 (GRB2)
   05214 Glioma
    104681311 (GRB2)
   05221 Acute myeloid leukemia
    104681311 (GRB2)
   05220 Chronic myeloid leukemia
    104681311 (GRB2)
   05211 Renal cell carcinoma
    104681311 (GRB2)
   05215 Prostate cancer
    104681311 (GRB2)
   05213 Endometrial cancer
    104681311 (GRB2)
   05224 Breast cancer
    104681311 (GRB2)
   05223 Non-small cell lung cancer
    104681311 (GRB2)
  09165 Substance dependence
   05034 Alcoholism
    104681311 (GRB2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    104681311 (GRB2)
   05160 Hepatitis C
    104681311 (GRB2)
   05163 Human cytomegalovirus infection
    104681311 (GRB2)
   05165 Human papillomavirus infection
    104681311 (GRB2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    104681311 (GRB2)
   01522 Endocrine resistance
    104681311 (GRB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rro04131]
    104681311 (GRB2)
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:rro04990]
    104681311 (GRB2)
Membrane trafficking [BR:rro04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    104681311 (GRB2)
Domain-containing proteins not elsewhere classified [BR:rro04990]
 Src homology (SH) domain-containing proteins
  Signal transducing adaptor proteins
   104681311 (GRB2)
SSDB
Motif
Pfam: SH3_1 SH3_9 SH3_2 SH2 SH3_10 SH2_2 SH3_3 DUF5093 hSH3 SH3_4
Other DBs
NCBI-GeneID: 104681311
NCBI-ProteinID: XP_010385914
UniProt: A0A2K6QZE3
LinkDB
Position
19
AA seq 217 aa
MEAIAKYDFKATADDELSFKRGDILKVLNEECDQNWYKAELNGKDGFIPKNYIEMKPHPW
FFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYFL
WVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDPQEDGELGFRRG
DFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 654 nt   +upstreamnt  +downstreamnt
atggaagccatcgccaaatatgacttcaaagctactgcagacgacgagctgagcttcaaa
aggggggacatcctcaaggttttgaacgaagaatgtgatcagaactggtacaaggcagag
cttaatggaaaagacggcttcattcccaagaactacatagaaatgaaaccacatccgtgg
ttttttggcaaaatccccagagccaaggcagaagaaatgcttagcaaacagcggcacgat
ggggcctttcttatccgagagagtgagagcgctcctggggacttctccctctctgtcaag
tttggaaacgatgtgcagcacttcaaggtgctccgagacggagccggcaagtacttcctc
tgggtggtgaagttcaattctttgaatgagctggtggattatcacagatctacatctgtc
tccagaaaccagcagatattcctgcgggacatagaacaggtgccacagcagccgacatac
gtccaggccctctttgactttgatccccaggaggatggagagctgggcttccgccgggga
gattttatccatgtcatggataactcagaccccaactggtggaaaggagcttgccacggg
cagaccggcatgtttccccgcaattacgtcacccctgtgaaccggaacgtctaa

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