KEGG   Rhinolophus sinicus (Chinese rufous horseshoe bat): 109447403Help
Entry
109447403         CDS       T04863                                 

Gene name
HK1
Definition
(RefSeq) hexokinase-1 isoform X1
  KO
K00844  hexokinase [EC:2.7.1.1]
Organism
rss  Rhinolophus sinicus (Chinese rufous horseshoe bat)
Pathway
rss00010  Glycolysis / Gluconeogenesis
rss00051  Fructose and mannose metabolism
rss00052  Galactose metabolism
rss00500  Starch and sucrose metabolism
rss00520  Amino sugar and nucleotide sugar metabolism
rss00524  Neomycin, kanamycin and gentamicin biosynthesis
rss01100  Metabolic pathways
rss01200  Carbon metabolism
rss04066  HIF-1 signaling pathway
rss04910  Insulin signaling pathway
rss04930  Type II diabetes mellitus
rss04973  Carbohydrate digestion and absorption
rss05230  Central carbon metabolism in cancer
Module
rss_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rss_M00549  Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:rss00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    109447403 (HK1)
   00051 Fructose and mannose metabolism
    109447403 (HK1)
   00052 Galactose metabolism
    109447403 (HK1)
   00500 Starch and sucrose metabolism
    109447403 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    109447403 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    109447403 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    109447403 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    109447403 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    109447403 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    109447403 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    109447403 (HK1)
Enzymes [BR:rss01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     109447403 (HK1)
Membrane trafficking [BR:rss04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    109447403 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Hexokinase_2 Hexokinase_1 CSD
Motif
Other DBs
NCBI-GeneID: 109447403
NCBI-ProteinID: XP_019587278
LinkDB All DBs
Position
Unknown
AA seq 917 aa AA seqDB search
MIAAQLLAYYFTELKDDQIKKIDKYLYAMRLSDETLIDIMIRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNQEKNQNVHMESEMYDTPENIMH
GSGSQLFDHVAECLGDFMEKKKIKDKKLPVGLTFSFPCRQSKIDEGILITWTKRFKVSGV
EGSDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTNDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVAVQHVCTIVSFRSANLVAATLGTILNRLRNNKGTPRLRTTVGVDGSLYKTH
PQYARRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFRLT
KEMLLEVKRRMRTEMDLGLQKQTNDKAVVKMLPSFVRSTPDGTEHGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPVEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCKQTSLDAGILITWTKGFKATDCVGHDVATLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMLEGNQGRMCINMEWGAFGDNGCLDD
IRTNYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRG
IFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSKRAAQLCGAGMAA
VVDKIRENRGLDHLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLREESSS
NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt
atgatcgccgcgcagctcctagcctattacttcactgagctgaaggatgaccaaataaaa
aagattgacaagtatctctatgccatgcggctctccgatgaaactctgatcgatatcatg
atccgtttcaagaaggagatgaagaatggtctttcccgggattttaatccgacagccaca
gtcaagatgttgccaacgtttgtaaggtccattcctgatggttcagaaaagggagatttc
attgccctggatcttggtgggtcttcctttcgaattttgcgggtccaagtgaatcaagag
aaaaaccagaatgttcacatggaatctgagatgtatgacaccccggagaacatcatgcac
ggcagtggaagccagctttttgatcatgttgctgagtgcctgggagacttcatggagaaa
aagaaaatcaaagacaagaaattacctgtgggacttacattttctttcccttgtcgacaa
tccaaaatcgatgagggtatcctcattacctggacaaagcgatttaaagtgagcggagtg
gagggatcggatgtggtgaagctgctcaacaaagccatcaaaaagcgtggggattatgac
gccaacattgtggctgtggtgaatgacacggtggggaccatgatgacctgtggctatgac
gaccagcagtgtgaagttggcctcatcattggcaccggcaccaacgcgtgttacatggag
gagttgaggcacattgacctggtggaaggcgacgagggcaggatgtgcatcaacaccgag
tggggggcgtttggggacgacggcgccctggaggacatccgcaccgagtttgaccgggag
atagaccggggatctctcaaccctggaaagcagctgtttgagaagatggtcagcggcatg
tacctgggggagctggttcgactgatcctagtcaagatggccaaggagggccttttattt
gaagggcggatcaccccagagctgctcaccagagggaagtttaacactaatgacgtctcg
gccatcgaaaagaataaagaaggccttcacaatgccaaagagatcctgacccgcctgggc
gtggagccgtctgacgacgactgtgttgccgtccagcacgtgtgcaccattgtgtcgttt
cgctctgccaacctggtggcagccacgctgggcaccatcctgaatcgccttcgaaataac
aagggcacccccaggctgcggaccacggttggtgtcgacgggtctctttacaagacacac
ccacagtatgcccggcgtttccacaagactctgaggcgcttggtgcctgactctgatgta
cgtttcctcctctcggagagtggcagcggcaagggggctgccatggtgacggccgtggcc
taccgcctggctgagcagcaccggcaaatagaagagaccctggcccacttccgcctcacc
aaagaaatgctgctggaggtgaagaggaggatgaggactgagatggacctggggctgcag
aagcagacaaacgataaggctgtagtcaagatgctgccctccttcgtccggagtactcca
gacgggactgagcatggtgacttcttggccttggatcttggaggaacaaatttccgtgtc
ctgctggtgaaaatccgtagtgggaaaaagaggacggtggaaatgcacaataagatctat
gccattcctgttgaaatcatgcagggcactggggaagagctatttgaccacatcgtctcc
tgcatctctgatttcctggactacatggggatcaaaggccccagaatgcctctgggcttc
acgttctccttcccctgcaagcagacaagtttggatgcgggaatcttgatcacctggacg
aagggatttaaggccacggattgcgtgggacacgatgtagccaccttactaagggatgcg
atcaaaaggagagaggagttcgacctggacgtggtggctgtcgtcaatgacacggtgggc
accatgatgacctgcgcctatgaggagcccacctgtgaggttggactcattgtagggact
ggcagcaatgcctgctacatggaagaaatgaagaacgtggagatgctggaggggaaccag
gggcgaatgtgtatcaatatggagtggggtgcctttggggacaacgggtgtctggatgat
atcagaaccaactatgaccgactggtggatgaatattctttaaacgctgggaaacaaagg
tatgagaagatgatcagcggcatgtacctgggcgagattgttcgcaatatcctcatcgac
ttcaccaagaaggggttcctcttccgagggcagatctctgagccactgaagacacggggc
atctttcagaccaagtatctctctcagatcgagagtgaccgattagcgctgctccaggtc
cgggccatcctccagcagctgggcctgaatagcacctgtgatgacagtatcctcgtcaag
accgtgtgcggggtagtgtccaagagggccgcgcagctgtgtggcgcaggcatggctgcc
gtggtggataagatccgagagaacagagggctggaccatctcaacgtgacagtgggagtg
gatggaacgctctacaagcttcatccacacttctccagaatcatgcaccaaaccgtgaag
gaactgtcaccaaagtgtaatgtgtcctttctgctgtcagaagacggtagtggcaagggg
gctgccctcatcacggcagtgggcgtacggctccgagaagaatcgagcagctaa

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