Streptomyces aquilus: EJC51_34020
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Entry
EJC51_34020 CDS
T07011
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
saqu
Streptomyces aquilus
Pathway
saqu00290
Valine, leucine and isoleucine biosynthesis
saqu00660
C5-Branched dibasic acid metabolism
saqu01100
Metabolic pathways
saqu01110
Biosynthesis of secondary metabolites
saqu01210
2-Oxocarboxylic acid metabolism
saqu01230
Biosynthesis of amino acids
Module
saqu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
saqu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
EJC51_34020 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EJC51_34020 (leuC)
Enzymes [BR:
saqu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
EJC51_34020 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
EJC51_34020 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
AZP20646
UniProt:
A0A3S9I8F5
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Position
7357484..7358908
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKSGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNAAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPLVRPKTMAITVNGELPEGVTA
KDLILAIIAKIGTGGGQGYVLEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDQTTF
DYLEGRVHAPKGEDWDAAVAYWKTLKTDEDAEFDAEVVIEAAELSPFVTWGTNPGQGAPL
SADVPDPASYEDASERLAAEKALEYMGLEAGQPLRSIKVDTVFVGSCTNGRIEDLRAAAE
LLKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKDAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDAPVAAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcatctgctgcacgaggtgaccagcccgcaggcc
ttcgacggcctccgcaagagcggtcgccaggtgcgccgcctcgacctcaccatcgcgacc
gaggaccacaacaccccgaccctcgacatcgacaagcccatcgccgacccggtctcccgg
gtccagctggagacgctgcgcaagaacgccgccgagttcggcgtgcgcctgcacccgctg
ggcgacgtcgagcagggcgtcgtgcacgtcgtcggcccccagctggggctgacccagccc
ggcatgacggtcgtctgcggcgactcccacacctccacgcacggcgccttcggcggtctg
gctttcggcatcggcacctcccaggtcgagcacgtgctggccacccagacgctgccgctg
gtccgcccgaagaccatggccatcacggtcaacggcgaactgcccgagggcgtcaccgcc
aaggacctgatcctggcgatcatcgccaagatcggcaccggcggcggccagggctacgtc
ctggagtaccgcggctccgccatcgagaaactctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggtgcccgcgcgggcatgatcgcccccgaccagaccaccttc
gactacctcgagggccgcgtgcacgcccccaagggcgaggactgggacgcggccgtcgcg
tactggaagaccctgaagacggacgaggacgcggagttcgacgccgaggtcgtcatcgag
gccgccgaactgtcgccgttcgtcacctggggcaccaaccccggtcagggcgcgccgctt
tcggcggacgtccccgatcctgcttcgtacgaagacgcttcggagcgcctcgccgccgaa
aaggccctggaatacatggggttggaggccgggcagccgctgcgctccatcaaggtggac
accgtcttcgtaggttcgtgcaccaacggccgtatcgaggacctgcgcgccgccgccgag
ctcctcaagggccgcaaagtcgccgacggcgtacggatgctggtcgttcccggctccgcg
cgggtcggtctccaggccgtctccgagggtctggacgtggtcttcaaggacgccggcgcc
gaatggcggcacgcgggctgctcgatgtgtctgggcatgaaccccgaccagctggccccg
ggtgagcgctccgcctccacctccaaccgcaacttcgagggacggcagggcaagggcggc
cgtacgcacctggtctcgccgcaggtcgccgccgcgaccgccgtgctgggccacctggcc
tcgcccgccgacctgtccgacgcccctgtcgccgctggagtctga
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