Staphylococcus aureus subsp. aureus SA268 (CA-MRSA): SA268_1971
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Entry
SA268_1971 CDS
T03790
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
saug
Staphylococcus aureus subsp. aureus SA268 (CA-MRSA)
Pathway
saug00290
Valine, leucine and isoleucine biosynthesis
saug00660
C5-Branched dibasic acid metabolism
saug01100
Metabolic pathways
saug01110
Biosynthesis of secondary metabolites
saug01210
2-Oxocarboxylic acid metabolism
saug01230
Biosynthesis of amino acids
Module
saug_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
saug00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SA268_1971 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SA268_1971 (leuC)
Enzymes [BR:
saug01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SA268_1971 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SA268_1971 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AII56538
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Position
2102979..2104349
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AA seq
456 aa
AA seq
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MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFAT
LDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPG
KTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAK
DIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFE
YVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPF
PEISDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNI
TAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRN
FEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgggtcaaacattatttgacaaggtgtggaacagacatgtgttatacggaaaattgggc
gaaccgcaactattatacattgatttacaccttatacatgaagttacttctcctcaagca
tttgaaggacttaggcttcaaaacagaaaattaagacgcccagatttaacatttgcaaca
ctcgatcacaatgttcctactattgatattttcaatattaaagatgaaattgcaaacaaa
caaatcacaacattacaaaaaaacgccatagattttggggtgcatatttttgatatgggt
tctgatgaacaaggtattgttcacatggtaggacctgagacaggacttacacagcctggc
aaaacgatcgtttgtggtgactctcacacagcaacacatggcgcatttggtgctattgca
tttggaattggaacaagtgaagttgaacatgttttcgcaactcaaacgctatggcaaaca
aaacccaaaaacttaaaaatcgatattaatggtaccttaccaacaggcgtctatgctaag
gacattattctgcatttaattaaaacgtatggtgttgattttggtacaggctatgctttg
gaatttactggcgaaacaattaaaaacctttcaatggacggtcgaatgactatttgtaac
atggctatcgaaggtggtgccaaatacggcataatccaacctgatgatataacatttgaa
tatgttaaagggagaccatttgccgataacttcgctaaatcagttgataagtggcgtgag
ctatattctgatgacgacgcgatatttgatcgtgtaattgaacttgatgtttcaacatta
gaaccacaagtgacatgggggactaatcctgaaatgggtgttaatttcagtgaaccattc
cctgaaatcagtgatatcaatgatcaacgtgcgtatgattatatggggttagaaccagga
caaaaagctgaagatatcgatttagggtatgttttcctcggttcatgtacaaatgctaga
ctatcagatttgattgaagctagtcatattgttaaaggaaataaagttcacccaaatatt
acagctattgtcgtaccaggttctcgtacagtaaaaaaagaagctgaaaaattaggtcta
gatactatctttaaaaatgcaggatttgaatggcgtgaaccaggatgttcaatgtgttta
ggcatgaatcctgaccaagtacctgagggtgtacattgtgcatctacaagtaatcgaaac
ttcgaaggacgacaaggcaaaggtgctagaacacatttagtatcccctgctatggcagca
gcagcagctattcatggtaaatttgtggacgtaagaaaggtggttgtttaa
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