Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA): SAV2059
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Entry
SAV2059 CDS
T00052
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sav
Staphylococcus aureus subsp. aureus Mu50 (MRSA/VISA)
Pathway
sav00290
Valine, leucine and isoleucine biosynthesis
sav00660
C5-Branched dibasic acid metabolism
sav01100
Metabolic pathways
sav01110
Biosynthesis of secondary metabolites
sav01210
2-Oxocarboxylic acid metabolism
sav01230
Biosynthesis of amino acids
Module
sav_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
SAV2059 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SAV2059 (leuC)
Enzymes [BR:
sav01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
SAV2059 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
SAV2059 (leuC)
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GFIT
Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
BAB58221
UniProt:
P63435
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All DBs
Position
2181527..2182897
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AA seq
456 aa
AA seq
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MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFAT
LDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPG
KTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAK
DIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFE
YVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPF
PEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNI
TAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRN
FEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
NT seq
1371 nt
NT seq
+upstream
nt +downstream
nt
atgggtcaaacattatttgacaaggtgtggaacagacatgtgttatacgggaaattgggc
gaaccgcaactattatacattgatttacaccttatacatgaagttacttctcctcaagca
tttgaaggacttaggcttcaaaacagaaaattaagacgcccagatttaacatttgcaaca
ctcgatcacaatgttcctactattgatattttcaatattaaagatgaaattgcaaacaaa
caaatcacaacattacaaaaaaacgccatagattttggggtgcatatttttgatatgggc
tctgatgaacaaggtattgttcacatggtaggacctgagacaggacttacacagcccggc
aaaacaatcgtttgtggtgactctcacacagcaacacatggagcatttggtgctattgca
tttggaattggaacaagtgaagttgaacatgttttcgcaactcaaacgctatggcaaaca
aaacccaaaaacttaaaaatcgatattaatggtaccttaccaacaggcgtctatgctaag
gacattattctgcatttaattaaaacgtatggtgttgattttggtacaggctatgctttg
gaatttactggcgaaacaattaaaaacctttcaatggacggtcgaatgactatttgtaac
atggctatcgaaggtggtgccaaatacggcataatccaacctgatgatataacatttgaa
tatgttaaagggagaccatttgccgataacttcgctaaatcagttgataagtggcgtgag
ctatattctgatgacgacgcgatatttgatcgtgtaattgaacttgatgtttcaacatta
gaaccacaagtgacatggggaactaatcctgaaatgggtgttaatttcagtgaaccattc
cctgaaatcaatgatatcaacgatcaacgtgcgtatgattatatggggttagaaccaggt
caaaaagctgaagacatcgacttagggtatgtttttctcggttcatgtacaaatgctaga
ctatcagatttgattgaagctagtcatattgttaaaggaaataaagttcatccaaatatt
acagctattgtcgtaccaggttctcgtacagtaaaaaaagaagcagaaaaattaggtcta
gatactatctttaaaaatgcaggatttgaatggcgtgaaccaggatgttcaatgtgttta
ggcatgaatcctgaccaagtacctgagggcgtacattgtgcatctacaagtaatcgaaac
tttgaaggacgacaaggcaaaggtgcaagaacacatttagtatcccctgctatggcagca
gcagcagctattcatggtaaatttgtggacgtaagaaaggtggttgtttaa
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