Streptomyces bingchenggensis: SBI_06012
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Entry
SBI_06012 CDS
T01678
Symbol
hemD
Name
(GenBank) putative uroporphyrin-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sbh
Streptomyces bingchenggensis
Pathway
sbh00860
Porphyrin metabolism
sbh01100
Metabolic pathways
sbh01110
Biosynthesis of secondary metabolites
sbh01120
Microbial metabolism in diverse environments
sbh01240
Biosynthesis of cofactors
Module
sbh_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
sbh_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
sbh_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
sbh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SBI_06012 (hemD)
Enzymes [BR:
sbh01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
SBI_06012 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SBI_06012 (hemD)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
ADI09132
UniProt:
D7CHT2
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All DBs
Position
7306651..7308198
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AA seq
515 aa
AA seq
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MLIADPQVLDVVRTHVRPGVAADAQGTPEQARADASSSTADVALLRDTANLVMGAARSGK
RVVRAVAGDPGLDGYAADEMVACAAEGIVFEVVPGVAAAVGVPAYAGVPLRDAQGTDVRF
VDARTADDRCWSEVGSSDATAVVSATLETVAAAAGELVAAGRKPDTPLTVTVAGTTTRQR
TWTATLGTIAQVLKAAKVLPSPQGAQPVIAVVGERSAAAQRDQLAWFESKPLFGWHVLVP
RTKEQAVSLSDQLRSYGAVPSEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAV
KAVREKFEEYGLDARAFAGIKVAAVGEQTAKSLIEFGVKPDLVPSGEQSAAGLLEDWPPY
DPVFDPIDRVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGF
DAVLFTSSSTVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVLSPEPSVHKLAEA
LAEFGAARRRAATQAGEPVTRPSERRPGSRRRARS
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
gtgctgatcgccgatccacaagtgctcgacgtggtacgtacgcacgtcaggccgggcgtg
gccgcggacgctcagggcacaccggagcaggcgagagctgacgcgtcgtcaagcaccgcc
gacgtggccctactcagggacacggccaatcttgtcatgggcgccgcgcggagcggcaag
cgggtcgtccgcgcggtcgcgggcgaccctggcctggacggatacgccgccgacgagatg
gtcgcgtgcgccgccgagggcatcgtcttcgaagtggtgcccggtgtggccgccgcggtg
ggcgtgcccgcgtatgcgggggtgccgctgcgggacgcacaaggcaccgatgtgcgcttc
gtggacgcccgtacggccgacgaccgctgctggagcgaggtcggctcctcggacgcgacc
gccgtggtctccgcgaccctggagacggtcgcggccgccgccggcgagctggtggccgcc
gggcgcaagcccgacaccccgctgaccgtcaccgtcgccggtacgaccacccggcagcgc
acctggacggcgacgctggggaccatcgcgcaggtgctgaaggcggcgaaggtgctgccg
tcgccgcagggcgcccagccggtgatagccgtcgtcggcgagcgcagcgcggccgcgcag
cgcgaccagctggcgtggttcgagtccaagccgctgttcggctggcatgtgctggtgccg
cgcaccaaggagcaggccgtctcgctctcggaccagctgcgctcgtacggcgcggtgccc
agcgaggtgccgaccatcgccgtggagccgccgcgcaccccgcagcagatggagcgcgcg
gtcaagggcctggtgaccggccgctacgagtggatcgccttcacctcggtcaacgcggtc
aaggcggtgcgggagaagttcgaggagtacgggctcgacgcccgcgccttcgccgggatc
aaggtcgcggcggtgggcgagcagaccgccaagtcgctcatcgagttcggggtcaagccg
gacctggtgcccagcggcgagcagtccgcggccgggctgctggaggactggccgccgtac
gacccggtcttcgacccgatcgaccgggtgttcctgccgcgcgccgatatcgccacggag
acgctggttgccgggctgatcgagctgggctgggaggtcgacgacgtcacggcgtaccgc
accgtgcgcgcctcgccgccgccggccgagacccgcgaggcgatcaagggcggcggcttc
gacgcggtgctcttcacctcgtcgtcgaccgtgcggaacctcgtcggcatcgcgggcaag
ccgcacaacgtcacggtcatcgcctgtatcggcccggccaccgcgaagaccgcggaggag
cacggcctgcgggtggatgtactctcgcccgagccctcggtgcacaagctggccgaggcg
ctcgcggagttcggggcggcccggcggcgggccgcgacccaggcaggggagccggtcacc
cgcccgagcgagcgccggcccggttcacgcaggagggcacgatcttga
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