Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101030999
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Entry
101030999 CDS
T04350
Gene name
PLCG2
Definition
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
KO
K05859
phosphatidylinositol phospholipase C, gamma-2 [EC:
3.1.4.11
]
Organism
sbq
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq00562
Inositol phosphate metabolism
sbq01100
Metabolic pathways
sbq01521
EGFR tyrosine kinase inhibitor resistance
sbq04012
ErbB signaling pathway
sbq04014
Ras signaling pathway
sbq04020
Calcium signaling pathway
sbq04062
Chemokine signaling pathway
sbq04064
NF-kappa B signaling pathway
sbq04066
HIF-1 signaling pathway
sbq04070
Phosphatidylinositol signaling system
sbq04072
Phospholipase D signaling pathway
sbq04360
Axon guidance
sbq04370
VEGF signaling pathway
sbq04380
Osteoclast differentiation
sbq04611
Platelet activation
sbq04613
Neutrophil extracellular trap formation
sbq04625
C-type lectin receptor signaling pathway
sbq04650
Natural killer cell mediated cytotoxicity
sbq04662
B cell receptor signaling pathway
sbq04664
Fc epsilon RI signaling pathway
sbq04666
Fc gamma R-mediated phagocytosis
sbq04670
Leukocyte transendothelial migration
sbq04722
Neurotrophin signaling pathway
sbq04750
Inflammatory mediator regulation of TRP channels
sbq04919
Thyroid hormone signaling pathway
sbq04933
AGE-RAGE signaling pathway in diabetic complications
sbq04935
Growth hormone synthesis, secretion and action
sbq05167
Kaposi sarcoma-associated herpesvirus infection
sbq05169
Epstein-Barr virus infection
sbq05170
Human immunodeficiency virus 1 infection
sbq05171
Coronavirus disease - COVID-19
sbq05200
Pathways in cancer
sbq05205
Proteoglycans in cancer
sbq05206
MicroRNAs in cancer
sbq05214
Glioma
sbq05223
Non-small cell lung cancer
sbq05225
Hepatocellular carcinoma
Module
sbq_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
sbq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101030999 (PLCG2)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101030999 (PLCG2)
04014 Ras signaling pathway
101030999 (PLCG2)
04370 VEGF signaling pathway
101030999 (PLCG2)
04064 NF-kappa B signaling pathway
101030999 (PLCG2)
04066 HIF-1 signaling pathway
101030999 (PLCG2)
04020 Calcium signaling pathway
101030999 (PLCG2)
04070 Phosphatidylinositol signaling system
101030999 (PLCG2)
04072 Phospholipase D signaling pathway
101030999 (PLCG2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101030999 (PLCG2)
04613 Neutrophil extracellular trap formation
101030999 (PLCG2)
04625 C-type lectin receptor signaling pathway
101030999 (PLCG2)
04650 Natural killer cell mediated cytotoxicity
101030999 (PLCG2)
04662 B cell receptor signaling pathway
101030999 (PLCG2)
04664 Fc epsilon RI signaling pathway
101030999 (PLCG2)
04666 Fc gamma R-mediated phagocytosis
101030999 (PLCG2)
04670 Leukocyte transendothelial migration
101030999 (PLCG2)
04062 Chemokine signaling pathway
101030999 (PLCG2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
101030999 (PLCG2)
04919 Thyroid hormone signaling pathway
101030999 (PLCG2)
09156 Nervous system
04722 Neurotrophin signaling pathway
101030999 (PLCG2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
101030999 (PLCG2)
09158 Development and regeneration
04360 Axon guidance
101030999 (PLCG2)
04380 Osteoclast differentiation
101030999 (PLCG2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101030999 (PLCG2)
05206 MicroRNAs in cancer
101030999 (PLCG2)
05205 Proteoglycans in cancer
101030999 (PLCG2)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101030999 (PLCG2)
05214 Glioma
101030999 (PLCG2)
05223 Non-small cell lung cancer
101030999 (PLCG2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101030999 (PLCG2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101030999 (PLCG2)
05171 Coronavirus disease - COVID-19
101030999 (PLCG2)
05167 Kaposi sarcoma-associated herpesvirus infection
101030999 (PLCG2)
05169 Epstein-Barr virus infection
101030999 (PLCG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101030999 (PLCG2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
sbq04131
]
101030999 (PLCG2)
Enzymes [BR:
sbq01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101030999 (PLCG2)
Membrane trafficking [BR:
sbq04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101030999 (PLCG2)
Endocytosis
Macropinocytosis
Phospholipase C
101030999 (PLCG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
SH2
PI-PLC-Y
C2
SH3_1
SH3_9
PH
SH3_2
PH_12
PH_14
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
101030999
NCBI-ProteinID:
XP_003938111
UniProt:
A0A2K6TJJ5
LinkDB
All DBs
Position
Unknown
AA seq
1265 aa
AA seq
DB search
MSTMASVDSLAEYEKSQIKRALELGTVMTVFSFRKSTPERRTVQVIMETRQVAWSKTADK
IEGFLDIMEIKEIRPGKNSKDFERAKAVRQKEDCCFTILYGNQFVLSTLSLAADSKEDAV
NWLSGLKILHQEAMNASTPTIIESWLRKQIYSVDQTRRNSISLRELKTILPLVNFKVSSA
KFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASA
VYLHDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENS
IWDEKYDAVDMQDMNNPLSHYWISSSHNTYLTGDQLRSESSTEAYIRCLRMGCRCIELDC
WDGPDGRPVIYHGWTRTTKIKFDDVVQAIKDHAFVTSSFPVILSIEEHCSVEQQRHMAKV
FKDIFGDLLLMKPTEASADQLPSPSQLREKIIIKHKKLGPRGDVDVNVEDKKDEHKQQGE
LYMWDSIDQKWTRHYCAIADAKLSFSDDIEQTMEEEVPQDIPPTELHFGEKWFHKKVEKR
TSAEKLLQEYCMETGGKDGTFLVRESETFPNDYTLSFWRSGRVQHCRIRSTMENGTLKYY
LTDNLTFNSIYALIQHYRETHLRCAEFELRLTDPVPNPNPHESKPWYYDSLSRGEAEDML
MRIPRDGAFLIRKREGSDSYAITFRARGKVKHCRINRDGRHFVLGTSAYFESLVELVSYY
EKHSLYRKMRLRYPVTPELLERYNMERDINSLYDVSRMYVDPSEINPSMPQRTVKALYDY
KAKRSDELSFCRGALIHNVSKEPGGWWKGDYGTRIQQYFPSNYVEDISTADVEELEKQII
EDNPLGSLCRGILDLNTYNVVKAPQGKNQKPFVFILEPKKQGDPPVEFATDRVEELFEWF
QSIREITWKIDTKENNMKYWEKNQSIAIELSDLVVYCKPTSKTKDNLENPDFREIRSFVE
TKADSIVRQKPVDLLKYNQKGLTRIYPKGQRVDSSNYDPFRLWLCGSQMVALNFQTADKY
MQMNHALFSLNGRTGYVLQPESMRTEKYDPMPPESQRKILLTLTVKVLGARHLPKPGRSI
ACPFVEVEICGAEYDNNKFKTTVVNDNGLNPIWAPTQEKVTFEIYDPNLAFLRFVVYEED
MFSDPNFLAHATYPIKAIKSGFRSVPLKNGYSEDIELASLLVFCEMRPVLESEEELYSSC
RQLRRRQEELNNQLFLYDTHQNLRNANRDALVKEFNVNENQLQLYQEKCNKRLREKRVSN
SKFYS
NT seq
3798 nt
NT seq
+upstream
nt +downstream
nt
atgtccaccatggctagtgtggattcccttgcggaatacgagaagagccagatcaagaga
gccctggagctggggacggtgatgactgtgttcagctttcgtaagtctactcctgagcga
aggaccgtccaggtgatcatggaaacgaggcaggtggcctggagcaagaccgccgacaag
attgagggcttcctggatatcatggaaataaaagaaatccgcccagggaagaactccaaa
gatttcgagcgtgcaaaagcagttcgccagaaagaagactgctgcttcaccatcctatat
ggcaatcagtttgtcctcagcacactcagcttggcagctgactctaaagaggatgcagtt
aactggctctctggcctgaaaatcttacaccaagaagcaatgaatgcatccacacccacc
attatcgagagttggctgagaaagcagatatattctgtggatcaaaccagaagaaacagc
atcagcctccgagagttgaagaccatcttgcccctcgtcaactttaaagtgagcagtgcc
aagttccttaaagataagtttgtggaaataggagcacacaaagatgagctgagctttgag
cagttccatctcttctataaaaaacttatgtttgaacagcaaaaatcgattctcgatgaa
ttcaaaaaggattcgtctgtgttcatcctggggaacacggacaggccggatgcctctgct
gtttaccttcatgactttcagaggtttctcatacatgaacagcaggagcactgggctcag
gatctgaacaaagtccgtgagcggatgacaaagttcatcgatgacaccatgcgtgaaacc
gctgagcctttcttgtttgtggatgagttcctcacgtacctgttttcacgagaaaacagc
atctgggatgagaagtatgacgcggtggatatgcaggacatgaacaaccccctgtctcat
tactggatctcctcgtcacataacacgtacctcacaggtgaccagctgcggagtgagtcg
tccacagaggcctacatccgctgcctgcgcatgggctgtcgctgcatcgaactggactgc
tgggacgggcccgatgggaggccggtcatctaccacggctggacgcggaccactaagatc
aagtttgatgacgtcgtgcaggccatcaaggaccacgcctttgtgacctcgagcttccca
gtgatcctgtccattgaggagcattgcagcgtggagcagcagcgccacatggccaaggtc
ttcaaagacatatttggcgatcttcttctgatgaagcccacggaggccagcgctgaccag
ctgccctcacccagccagctgcgggagaagatcatcatcaagcataagaagctgggcccc
cgaggtgacgtggatgtcaacgtggaggataagaaggatgagcacaagcaacagggagag
ctgtacatgtgggattccatcgaccagaaatggactcggcactactgcgccatcgccgat
gccaagctgtccttcagtgatgacattgaacagactatggaggaggaagtgccccaggat
atacctcccacagagctgcattttggggagaaatggttccacaagaaggtggagaagagg
acgagtgctgagaagttgctgcaggaatactgcatggagacagggggcaaggatggcacc
ttcctggtccgggagagcgagaccttccccaatgactacactctgtccttctggcggtca
ggccgggtccagcactgccggatacgctccaccatggagaatgggaccctgaagtactac
ctgactgacaacctcaccttcaacagcatctacgccctcatccagcactaccgcgagacg
cacctgcgctgtgccgaattcgagctgcggctcaccgaccctgtgcccaaccccaacccc
cacgagtccaagccgtggtactatgacagcctgagtcgcggagaggcagaggacatgctg
atgaggatcccccgggacggagccttcctaatccggaagcgagagggcagcgactcctac
gccatcaccttcagggctaggggcaaggtgaagcactgtcgcatcaaccgggatggccga
cactttgttctgggaacctccgcctattttgagagcctggtggagctcgtcagttactat
gagaagcattcactctaccgaaagatgagactgcgctaccccgtgacgcccgagctcctg
gagcgctacaatatggaaagagatataaactccctctatgacgtcagcagaatgtatgtg
gatcccagtgaaatcaatccgtccatgcctcagagaactgtgaaagccctgtatgactac
aaagccaagcgaagcgatgagctgagcttctgccggggcgccctcatccacaatgtctcc
aaggagcccgggggctggtggaaaggtgactatggaaccaggatccagcagtacttccca
tccaactacgtggaggacatctcaactgcagatgtcgaggagctggaaaagcagatcatt
gaagacaatcccttagggtctctttgcagaggcatattggacctcaatacctataacgtc
gtgaaagccccacaggggaaaaaccagaagccctttgtctttatcctggagcccaagaag
cagggtgatcctccggtggagtttgccacagacagggtggaggagctcttcgagtggttt
cagagcatccgagagatcacctggaagatcgacaccaaggagaacaacatgaagtattgg
gagaagaaccagtctatcgccatcgagctctctgacctggttgtctactgcaaaccaacc
agcaaaaccaaggacaacttagaaaatcctgacttcagagaaatccgctcctttgtggag
acaaaggctgacagcatcgtcagacagaagcccgtcgacctcctcaagtacaatcaaaag
ggactgacccgcatctacccaaagggacaaagagttgactcttccaactatgaccccttc
cgcctctggctgtgcggttctcagatggtggcactcaatttccagacggcagataagtac
atgcagatgaatcacgcattgttttctctgaatgggcgcacgggctacgttctgcagcct
gagagcatgaggacagagaaatacgacccgatgccacccgagtcccagaggaagatcctg
ctgacgctgactgtcaaggttctcggtgctcgccatctccccaaacctggacgaagtatt
gcctgtccctttgtagaggtggagatctgtggagctgagtatgacaacaacaagttcaaa
acgacggttgtgaatgataatggcctcaatcctatctgggctccaacacaggagaaggtg
acatttgaaatttatgacccaaacctggcatttctgcgcttcgtggtttacgaagaagat
atgttcagtgatcccaacttccttgctcatgccacttaccccattaaagcaatcaagtca
ggattcagatctgttcctctgaagaatgggtacagtgaggacatcgagctggcttccctc
ctggttttctgtgaaatgcggccagtcctggagagcgaagaggaactttactcctcctgt
cgccagctgaggcggcggcaagaagaactgaacaaccagctttttctatatgacacacac
cagaacttgcgcaatgccaaccgggatgccctggttaaagagttcaacgttaacgagaac
cagctccagttgtaccaggagaaatgcaacaagaggttaagagagaagagagtcagcaac
agcaagttttactcgtag
DBGET
integrated database retrieval system
