KEGG T04350: 101040507

KEGG Orthology (KO) [BR:sbq00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101040507 (CDK6)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101040507 (CDK6)
   04115 p53 signaling pathway
    101040507 (CDK6)
   04218 Cellular senescence
    101040507 (CDK6)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101040507 (CDK6)
   05206 MicroRNAs in cancer
    101040507 (CDK6)
   05203 Viral carcinogenesis
    101040507 (CDK6)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101040507 (CDK6)
   05225 Hepatocellular carcinoma
    101040507 (CDK6)
   05214 Glioma
    101040507 (CDK6)
   05220 Chronic myeloid leukemia
    101040507 (CDK6)
   05218 Melanoma
    101040507 (CDK6)
   05224 Breast cancer
    101040507 (CDK6)
   05222 Small cell lung cancer
    101040507 (CDK6)
   05223 Non-small cell lung cancer
    101040507 (CDK6)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101040507 (CDK6)
  09172 Infectious disease: viral
   05160 Hepatitis C
    101040507 (CDK6)
   05164 Influenza A
    101040507 (CDK6)
   05162 Measles
    101040507 (CDK6)
   05163 Human cytomegalovirus infection
    101040507 (CDK6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101040507 (CDK6)
   05169 Epstein-Barr virus infection
    101040507 (CDK6)
   05165 Human papillomavirus infection
    101040507 (CDK6)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sbq01001]
    101040507 (CDK6)
Enzymes [BR:sbq01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     101040507 (CDK6)
Protein kinases [BR:sbq01001]
Serine/threonine kinases: CMGC group
  CDK family
   101040507 (CDK6)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr APH Kdo Kinase-like RIO1 FTA2 Seadorna_VP7

Other DBs

NCBI-GeneID:

101040507

NCBI-ProteinID:

XP_010343625

UniProt:

A0A2K6V0N9

LinkDB

Position

Unknown

AA seq 326 aa
MEKDGLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSNGQIKLADFGLARIYSFQMALTSVV
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
EDWPRDVALPRQAFHAKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
QDLERCRESLDSHLPPSQNTSEMNTA

NT seq 981 nt +upstreamnt +downstreamnt
atggagaaggacggcctgagccgcgcggaccagcagtacgaatgcgtggcggagatcggg
gagggcgcctatggaaaggtgttcaaggcccgagacttgaagaacggaggccgtttcgtg
gcgttgaagcgcgtgcgggtgcagaccggcgaggagggcatgcctctctccaccatccgc
gaggtggcagtgctgaggcacctggagaccttcgagcaccccaacgtggtcaggttgttt
gatgtgtgcacagtgtcacgaactgacagagaaaccaaactaactttagtgtttgaacat
gtcgatcaagacttgaccacttacttggataaagttccagagcctggagtgcccactgaa
actataaaggatatgatgtttcagcttctccgaggtctggactttcttcattcacaccga
gtagtgcatcgtgatctaaaaccacaaaacattctggtgaccagcaacggacaaataaaa
ctcgctgactttggccttgcccgcatctacagtttccagatggctctaacttcagtggtc
gtcacgctgtggtacagagcgcccgaagtcttgctccagtccagctacgccacccccgtg
gatctctggagtgttggctgcatatttgcagaaatgtttcgtagaaagcctctttttcgt
ggaagttcagatgtcgatcaactaggaaaaatcttggacgtaattggactcccaggagaa
gaagactggcctagagatgttgcccttcccaggcaggcttttcatgcaaaatctgcccaa
ccaattgagaagtttgtgacagatatcgatgaactaggcaaagacctacttctgaagtgt
ttgacatttaacccagccaaaagaatatctgcctacagcgccctgtctcacccatacttc
caggacctggagaggtgcagagaaagcctggattcccacctgcctcccagccagaacacc
tcggagatgaatacagcctga

Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101040767

Entry

101040767 CDS T04350

Gene name

CDK4

Definition

(RefSeq) cyclin-dependent kinase 4

K02089

cyclin-dependent kinase 4 [EC:2.7.11.22]

Organism

sbq Saimiri boliviensis boliviensis (Bolivian squirrel monkey)

Pathway

sbq01522

Endocrine resistance

sbq04110

Cell cycle

sbq04115

p53 signaling pathway

sbq04151

PI3K-Akt signaling pathway

sbq04218

Cellular senescence

sbq04530

Tight junction

sbq04660

T cell receptor signaling pathway

sbq04933

AGE-RAGE signaling pathway in diabetic complications

sbq04934

Cushing syndrome

sbq05160

Hepatitis C

sbq05162

Measles

sbq05163

Human cytomegalovirus infection

sbq05164

Influenza A

sbq05165

Human papillomavirus infection

sbq05166

Human T-cell leukemia virus 1 infection

sbq05167

Kaposi sarcoma-associated herpesvirus infection

sbq05169

Epstein-Barr virus infection

sbq05200

Pathways in cancer

sbq05203

Viral carcinogenesis

sbq05212

Pancreatic cancer

sbq05214

Glioma

sbq05218

Melanoma

sbq05219

Bladder cancer

sbq05220

Chronic myeloid leukemia

sbq05222

Small cell lung cancer

sbq05223

Non-small cell lung cancer

sbq05224

Breast cancer

sbq05225

Hepatocellular carcinoma

Brite

KEGG Orthology (KO) [BR:sbq00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    101040767 (CDK4)
09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    101040767 (CDK4)
   04115 p53 signaling pathway
    101040767 (CDK4)
   04218 Cellular senescence
    101040767 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    101040767 (CDK4)
09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    101040767 (CDK4)
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101040767 (CDK4)
   05203 Viral carcinogenesis
    101040767 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    101040767 (CDK4)
   05225 Hepatocellular carcinoma
    101040767 (CDK4)
   05214 Glioma
    101040767 (CDK4)
   05220 Chronic myeloid leukemia
    101040767 (CDK4)
   05218 Melanoma
    101040767 (CDK4)
   05219 Bladder cancer
    101040767 (CDK4)
   05224 Breast cancer
    101040767 (CDK4)
   05222 Small cell lung cancer
    101040767 (CDK4)
   05223 Non-small cell lung cancer
    101040767 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101040767 (CDK4)
   04934 Cushing syndrome
    101040767 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101040767 (CDK4)
   05160 Hepatitis C
    101040767 (CDK4)
   05164 Influenza A
    101040767 (CDK4)
   05162 Measles
    101040767 (CDK4)
   05163 Human cytomegalovirus infection
    101040767 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101040767 (CDK4)
   05169 Epstein-Barr virus infection
    101040767 (CDK4)
   05165 Human papillomavirus infection
    101040767 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101040767 (CDK4)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sbq01001]
    101040767 (CDK4)
Enzymes [BR:sbq01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     101040767 (CDK4)
Protein kinases [BR:sbq01001]
Serine/threonine kinases: CMGC group
  CDK family
   101040767 (CDK4)

SSDB

Motif

Pfam:

Pkinase PK_Tyr_Ser-Thr APH Kdo Kinase-like FTA2

Other DBs

NCBI-GeneID:

101040767

NCBI-ProteinID:

XP_003926545

UniProt:

A0A2K6V2B6

LinkDB

Position

Unknown

AA seq 302 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAGGGLPVSTVREVALLR
RLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLM
RQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYR
APEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRD
VSLPRGAFHPRGPRPVQSVVPEMEELGAHLLLEMLTFNPHKRISAFRALQHSYLHKDEGN
QE

NT seq 909 nt +upstreamnt +downstreamnt
atggctacctctcgatatgagccagtggctgaaattggtgtcggtgcctatgggacagtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtcccc
aatggaggagctggaggaggccttcccgtcagcacagttcgtgaagtggctttactgagg
cgactggaggcttttgagcatcccaacgtagtccggctgatggatgtctgtgccacatcc
cgaactgaccgagagatcaaggtaaccctggtgtttgagcatgtagaccaagatctaagg
acgtatctggacaaggcacccccaccaggcttgccagctgagaccatcaaggatctgatg
cgccagtttctaagaggcctagattttcttcatgccaattgcatcgttcaccgagatctg
aagccagagaacattctggtgacaagtggtggaacagtcaagctggctgactttggcctg
gcgagaatctacagctaccagatggcacttacacccgtggttgttacactctggtaccga
gctcccgaagttcttctgcagtccacatatgcaacacctgtggacatgtggagtgttggc
tgtatctttgctgagatgtttcgtcgaaagcctctcttctgcggaaactctgaagctgac
cagttgggcaaaatctttgacctgattgggctgcctccagaggatgactggcctcgagat
gtatctctgccccgtggagcctttcacccccgagggccccgcccagtgcagtcggtggta
cccgagatggaggagttgggagcacatctgctgctggaaatgctgacttttaacccacac
aagcgaatctctgcctttcgagctctgcagcactcttatctacataaggatgaaggtaat
caagagtga

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