KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101053601
Entry
101053601         CDS       T04350                                 

Gene name
CASP8
Definition
(RefSeq) caspase-8 isoform X1
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq01524  Platinum drug resistance
sbq04115  p53 signaling pathway
sbq04210  Apoptosis
sbq04215  Apoptosis - multiple species
sbq04217  Necroptosis
sbq04620  Toll-like receptor signaling pathway
sbq04621  NOD-like receptor signaling pathway
sbq04622  RIG-I-like receptor signaling pathway
sbq04625  C-type lectin receptor signaling pathway
sbq04657  IL-17 signaling pathway
sbq04668  TNF signaling pathway
sbq04932  Non-alcoholic fatty liver disease
sbq05010  Alzheimer disease
sbq05016  Huntington disease
sbq05022  Pathways of neurodegeneration - multiple diseases
sbq05132  Salmonella infection
sbq05134  Legionellosis
sbq05142  Chagas disease
sbq05145  Toxoplasmosis
sbq05152  Tuberculosis
sbq05160  Hepatitis C
sbq05161  Hepatitis B
sbq05162  Measles
sbq05163  Human cytomegalovirus infection
sbq05164  Influenza A
sbq05165  Human papillomavirus infection
sbq05167  Kaposi sarcoma-associated herpesvirus infection
sbq05168  Herpes simplex virus 1 infection
sbq05169  Epstein-Barr virus infection
sbq05170  Human immunodeficiency virus 1 infection
sbq05200  Pathways in cancer
sbq05203  Viral carcinogenesis
sbq05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    101053601 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101053601 (CASP8)
   04215 Apoptosis - multiple species
    101053601 (CASP8)
   04217 Necroptosis
    101053601 (CASP8)
   04115 p53 signaling pathway
    101053601 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101053601 (CASP8)
   04621 NOD-like receptor signaling pathway
    101053601 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    101053601 (CASP8)
   04625 C-type lectin receptor signaling pathway
    101053601 (CASP8)
   04657 IL-17 signaling pathway
    101053601 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101053601 (CASP8)
   05203 Viral carcinogenesis
    101053601 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101053601 (CASP8)
   05016 Huntington disease
    101053601 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    101053601 (CASP8)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    101053601 (CASP8)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    101053601 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101053601 (CASP8)
   05134 Legionellosis
    101053601 (CASP8)
   05152 Tuberculosis
    101053601 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101053601 (CASP8)
   05161 Hepatitis B
    101053601 (CASP8)
   05160 Hepatitis C
    101053601 (CASP8)
   05164 Influenza A
    101053601 (CASP8)
   05162 Measles
    101053601 (CASP8)
   05168 Herpes simplex virus 1 infection
    101053601 (CASP8)
   05163 Human cytomegalovirus infection
    101053601 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101053601 (CASP8)
   05169 Epstein-Barr virus infection
    101053601 (CASP8)
   05165 Human papillomavirus infection
    101053601 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101053601 (CASP8)
   05142 Chagas disease
    101053601 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101053601 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:sbq01002]
    101053601 (CASP8)
Enzymes [BR:sbq01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     101053601 (CASP8)
Peptidases and inhibitors [BR:sbq01002]
 Cysteine peptidases
  Family C14: caspase family
   101053601 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED PYRIN
Other DBs
NCBI-GeneID: 101053601
NCBI-ProteinID: XP_003925706
UniProt: A0A2K6TPK0
LinkDB
Position
Unknown
AA seq 494 aa
MVPGKGGEDYILLPFEKMAFSRMLFNIGEELGSEELAALKFLSLDYIQQRKQEPIKDALM
LFQRLQEKRMLEESNLSFLKEMLFRINRLDLLNKYLDTSKEEMERELQTPGSAQISAYRV
MLYQISEDVSKTELRSFKFLLKKEISKCKLDDDMNLLDIFIEMEKRVILGEEKLDVLKRV
CDQINKSLLKIINDYECSRERMSLERSSDESSNGEELFGVMAISDSPREQDSESQTSDKV
YQMKSKPRGYCLIINNHDFRKAREEVPKHHRIKDRNGTHLDAEALSKTFKELHFEIKPYN
DCTAERIYEILQIYQRMDHSNKDCFICCILSHGDKGIIYGTDGREAPIYELTSQFTGLKC
PSLAGKPKVFFIQACQGDNYQKGIPVETDSEKQPYLEMDLSSPQTRYIPDEADFLLGMAT
VNNCVSYRNPVEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQ
PTFTLRKKLVFSSD
NT seq 1485 nt   +upstreamnt  +downstreamnt
atggtgcccggaaagggtggagaggattacatcctcctaccttttgaaaagatggccttc
agcagaatgctttttaatattggagaagaactgggaagtgaagaactggccgccctcaag
ttcctgagcctggactacatccaacaaaggaagcaagaacccatcaaggatgccttgatg
ttattccagagactccaggaaaagagaatgttggaggaaagtaatctgtcctttctgaag
gagatgctcttccgaattaatagattggatttgctgaataaatatctagacactagcaag
gaggagatggaaagggaacttcagacaccgggcagcgctcagatttctgcctacagggtc
atgctctatcagatttcagaagatgtgagcaaaacagaattgaggtcttttaagtttctt
ttgaaaaaggagatctccaaatgcaaactggatgacgatatgaacctgctggatattttc
atagagatggagaagagggtcatcctgggagaagaaaagttggacgtcctgaaaagagtc
tgtgaccaaatcaacaagagcctgctgaagataatcaacgactatgaatgcagcagagag
agaatgagccttgaaagaagttcagatgaatcttcaaatggggaggagttgtttggggta
atggcaatctcggactctccaagagaacaggatagtgaatcacagacttcggacaaagtt
taccaaatgaaaagcaaacctcggggatattgtctgatcatcaacaatcatgattttcgc
aaagcacgggaggaagtgcccaaacaccaccgcattaaggacaggaatggaacacacctg
gatgcagaggctttgagcaagacctttaaagagcttcattttgagatcaagccctacaat
gactgcacagcagagagaatctatgagattttgcaaatctaccaacgcatggaccacagt
aacaaggactgcttcatctgctgtatcctctcccatggagacaagggcatcatctacggc
acggatggacgtgaggcccccatatatgagctgacatctcagttcactggtttgaagtgc
ccttcccttgctggaaaaccgaaagtgttttttattcaggcttgtcagggggataactac
cagaaaggtatacctgttgagactgattcagagaagcaaccttatttggaaatggactta
tcatcacctcagacgagatacatcccagatgaggctgactttctactggggatggccact
gtgaataactgtgtttcctaccgaaaccctgtggagggaacctggtatatccagtcactt
tgccagagcctgagagaacgatgtcctcgaggcgatgatattctcaccatcctgactgaa
gtgaactatgaagtcagcaacaaagacgataagaaaaacatggggaagcagatgccgcag
cctactttcacactaagaaaaaaacttgttttctcttctgactga

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