KEGG   Saimiri boliviensis boliviensis (Bolivian squirrel monkey): 101053608
Entry
101053608         CDS       T04350                                 

Gene name
TBK1
Definition
(RefSeq) serine/threonine-protein kinase TBK1
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
sbq  Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Pathway
sbq04014  Ras signaling pathway
sbq04137  Mitophagy - animal
sbq04140  Autophagy - animal
sbq04620  Toll-like receptor signaling pathway
sbq04621  NOD-like receptor signaling pathway
sbq04622  RIG-I-like receptor signaling pathway
sbq04623  Cytosolic DNA-sensing pathway
sbq04657  IL-17 signaling pathway
sbq05014  Amyotrophic lateral sclerosis
sbq05022  Pathways of neurodegeneration - multiple diseases
sbq05135  Yersinia infection
sbq05160  Hepatitis C
sbq05161  Hepatitis B
sbq05162  Measles
sbq05163  Human cytomegalovirus infection
sbq05164  Influenza A
sbq05165  Human papillomavirus infection
sbq05167  Kaposi sarcoma-associated herpesvirus infection
sbq05168  Herpes simplex virus 1 infection
sbq05169  Epstein-Barr virus infection
sbq05170  Human immunodeficiency virus 1 infection
sbq05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:sbq00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101053608 (TBK1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101053608 (TBK1)
   04137 Mitophagy - animal
    101053608 (TBK1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101053608 (TBK1)
   04621 NOD-like receptor signaling pathway
    101053608 (TBK1)
   04622 RIG-I-like receptor signaling pathway
    101053608 (TBK1)
   04623 Cytosolic DNA-sensing pathway
    101053608 (TBK1)
   04657 IL-17 signaling pathway
    101053608 (TBK1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101053608 (TBK1)
   05022 Pathways of neurodegeneration - multiple diseases
    101053608 (TBK1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101053608 (TBK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101053608 (TBK1)
   05161 Hepatitis B
    101053608 (TBK1)
   05160 Hepatitis C
    101053608 (TBK1)
   05171 Coronavirus disease - COVID-19
    101053608 (TBK1)
   05164 Influenza A
    101053608 (TBK1)
   05162 Measles
    101053608 (TBK1)
   05168 Herpes simplex virus 1 infection
    101053608 (TBK1)
   05163 Human cytomegalovirus infection
    101053608 (TBK1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101053608 (TBK1)
   05169 Epstein-Barr virus infection
    101053608 (TBK1)
   05165 Human papillomavirus infection
    101053608 (TBK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:sbq01001]
    101053608 (TBK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:sbq04131]
    101053608 (TBK1)
Enzymes [BR:sbq01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     101053608 (TBK1)
Protein kinases [BR:sbq01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   101053608 (TBK1)
Membrane trafficking [BR:sbq04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    101053608 (TBK1)
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal Kinase-like DUF713 CEP63 ubiquitin
Other DBs
NCBI-GeneID: 101053608
NCBI-ProteinID: XP_003926572
UniProt: A0A2K6U0D9
LinkDB
Position
Unknown
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATIFHELVYKQTKILSSNQELIYEGRRLI
LEPGKLAQHFPKTTEENPIFVVSREPLNTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIDSRLSPGGLLADTWAHQE
GTHPKDRNVEKLQVLLNCMTEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLSKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNDLQETLPQ
KMFAASSGIKHTMTPIYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLHNVDCL
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcagatgagggaatttgaagtgttgaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgtggaagtttatacactgttttagaagag
ccatctaatgcctatggactaccagaatctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctgcgagagaatggcatagtgcaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtatacaagctcacagattttggtgca
gctagagaattagaagatgacgaacagtttgtttctctgtatggcacagaagaatatttg
caccctgatatgtatgagagagcagtgctgaggaaagatcatcagaagaaatatggagcg
acagttgatctttggagcattggggtaacattttaccatgccgctactggatcactgcca
tttagaccctttgaagggcctcgtaggaataaagaagtgatgtataaaataattacagga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctgtttcttgcagtctttctcggggtcttcaggttctacttactcctgtt
cttgcaaacatccttgaagcggatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcaccgtatgataattcatgttttttcgctacaacaaatgaca
gctcataagatttatattcatagctataatactgctactatatttcatgaactggtgtat
aaacaaaccaaaattctttcttcaaatcaagaacttatctatgaaggacgacgcttaata
ttagaacctggaaaactagcacagcatttccctaaaactactgaggaaaatcccatcttt
gtagtaagccgggaacctttgaataccataggattaatatatgaaaaaatttccctccct
aaagtgcatccacggtatgatttagatggggatgctagcatggctaaggcaataacaggg
gttgtgtgttatgcctgcagaattgccagtaccttactgctttatcaggaattaatgcga
aaggggatacgatggctgattgaattagttaaagatgattacaatgaaactgttcacaaa
aagacagaagttgtgatcacattggatttctgtatcagaaacattgaaaaaactgtgaaa
gtttacgaaaagttgatgaagatcaacctagaagcggcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgacagcagactgtctccaggcggattgctggcagatacatgggcacatcaagaa
ggcactcatccaaaagacagaaatgtagaaaaactacaagtcctgttaaattgcatgaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcgtataatgaagaa
caaatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacacac
tttacagatgagtgtgttaaaaagtatgaggcatttttgagtaagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatctctgactaatcagtgttttgatatt
gaagaagaagtatcaaagtatcaagactatactaatgatttacaagaaactttgcctcag
aaaatgtttgcagcttccagtggaatcaaacataccatgaccccaatttatccaagttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagagatggaaggagtg
gttaaagaacttgctgaaaataaccacattttagaaaggtttggctctttaaccatggat
ggtggccttcacaatgttgactgtctttag

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